Pereiti prie turinio
Naudokite savo HSA ar FSA lėšas

Požymis

Zygomatic flattening

Klinikinis pavadinimas: Malar flattening

Underdevelopment of the malar prominence of the jugal bone (zygomatic bone in mammals), appreciated in profile, frontal view, and/or by palpation.

HPO HP:0000272

Santrauka

Taip pat vadinama
Decreased size of malar bone, Depressed malar region, Flat cheekbone, Malar hypoplasia, Underdevelopment of malar bone
Kūno sistema
Abnormality of head or neckAbnormality of the musculoskeletal system

128 condition reports read genes linked to this trait

Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.

Show 124 more reports

Every condition report

Vienu tyrimu sužinokite genus, susijusius su Zygomatic flattening, ir kitą jūsų genomo dalį.

Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites

Įsigyti savo Genome Test

217 genų susiję su Zygomatic flattening

Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Zygomatic flattening. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.

GenasKaip dažnai pasireiškiaLigos
ACANaggrecanVisada1 ligoje
ASPHaspartate beta-hydroxylaseVisada1 ligoje
BBS7Bardet-Biedl syndrome 7Visada1 ligoje
CANT1calcium activated nucleotidase 1Visada1 ligoje
COL11A2collagen type XI alpha 2 chainVisada4 ligose
COL2A1collagen type II alpha 1 chainVisada6 ligose
FGFR1fibroblast growth factor receptor 1Visada2 ligose
FLVCR1FLVCR choline and heme transporter 1Visada1 ligoje
FOXP1forkhead box P1Visada1 ligoje
HNRNPH1heterogeneous nuclear ribonucleoprotein H1Visada1 ligoje
HS6ST2heparan sulfate 6-O-sulfotransferase 2Visada1 ligoje
KDM6Blysine demethylase 6BVisada1 ligoje
KIF7kinesin family member 7Visada1 ligoje
MECP2methyl-CpG binding protein 2Visada1 ligoje
NONOnon-POU domain containing octamer bindingVisada2 ligose
NOTCH2notch receptor 2Visada1 ligoje
NOTCH3notch receptor 3Visada2 ligose
OBSL1obscurin like cytoskeletal adaptor 1Visada1 ligoje
PIGUphosphatidylinositol glycan anchor biosynthesis class UVisada1 ligoje
PLOD3procollagen-lysine,2-oxoglutarate 5-dioxygenase 3Visada1 ligoje
POLR1BRNA polymerase I subunit BVisada2 ligose
POLR1CRNA polymerase I and III subunit CVisada2 ligose
PSMC3proteasome 26S subunit, ATPase 3Visada1 ligoje
RDH11retinol dehydrogenase 11Visada2 ligose
TBL1XR1TBL1X/Y related 1Visada2 ligose
TMEM165transmembrane protein 165Visada1 ligoje
ACSL4acyl-CoA synthetase long chain family member 4Labai dažnai (80–99%)1 ligoje
AMMECR1AMMECR nuclear protein 1Labai dažnai (80–99%)1 ligoje
ATP6V0A2ATPase H+ transporting V0 subunit a2Labai dažnai (80–99%)2 ligose
ATP6V1AATPase H+ transporting V1 subunit ALabai dažnai (80–99%)1 ligoje
ATP6V1E1ATPase H+ transporting V1 subunit E1Labai dažnai (80–99%)2 ligose
BGNbiglycanLabai dažnai (80–99%)1 ligoje
COG4component of oligomeric golgi complex 4Labai dažnai (80–99%)1 ligoje
COL11A1collagen type XI alpha 1 chainLabai dažnai (80–99%)4 ligose
DHODHdihydroorotate dehydrogenase (quinone)Labai dažnai (80–99%)2 ligose
EFTUD2elongation factor Tu GTP binding domain containing 2Labai dažnai (80–99%)2 ligose
ESCO2establishment of sister chromatid cohesion N-acetyltransferase 2Labai dažnai (80–99%)2 ligose
FGFR2fibroblast growth factor receptor 2Labai dažnai (80–99%)8 ligose
FLNAfilamin ALabai dažnai (80–99%)4 ligose
FLNBfilamin BLabai dažnai (80–99%)4 ligose
Rodyti dar 177 genų
GenasKaip dažnai pasireiškiaLigos
HDAC4histone deacetylase 4Labai dažnai (80–99%)1 ligoje
INPPL1inositol polyphosphate phosphatase like 1Labai dažnai (80–99%)1 ligoje
KCNE5potassium voltage-gated channel subfamily E regulatory subunit 5Labai dažnai (80–99%)1 ligoje
LARP7La ribonucleoprotein 7, transcriptional regulatorLabai dažnai (80–99%)2 ligose
NSDHLNAD(P) dependent 3-beta-hydroxysteroid dehydrogenase NSDHLLabai dažnai (80–99%)2 ligose
PDE4Dphosphodiesterase 4DLabai dažnai (80–99%)2 ligose
POLR1DRNA polymerase I and III subunit DLabai dažnai (80–99%)2 ligose
POLR3ARNA polymerase III subunit ALabai dažnai (80–99%)2 ligose
PQBP1polyglutamine binding protein 1Labai dažnai (80–99%)2 ligose
PTH1Rparathyroid hormone 1 receptorLabai dažnai (80–99%)2 ligose
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1Labai dažnai (80–99%)1 ligoje
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2Labai dažnai (80–99%)1 ligoje
RAI1retinoic acid induced 1Labai dažnai (80–99%)1 ligoje
RSPRY1ring finger and SPRY domain containing 1Labai dažnai (80–99%)2 ligose
SCARF2scavenger receptor class F member 2Labai dažnai (80–99%)2 ligose
SF3B4splicing factor 3b subunit 4Labai dažnai (80–99%)2 ligose
SLC35D1solute carrier family 35 member D1Labai dažnai (80–99%)2 ligose
TBX22T-box transcription factor 22Labai dažnai (80–99%)1 ligoje
TCOF1treacle ribosome biogenesis factor 1Labai dažnai (80–99%)2 ligose
TFAP2Btranscription factor AP-2 betaLabai dažnai (80–99%)1 ligoje
TGDSTDP-glucose 4,6-dehydrataseLabai dažnai (80–99%)1 ligoje
YY1YY1 transcription factorLabai dažnai (80–99%)2 ligose
ZNHIT3zinc finger HIT-type containing 3Labai dažnai (80–99%)1 ligoje
ADAMTSL4ADAMTS like 4Dažnai (30–79%)1 ligoje
ARID1BAT-rich interaction domain 1BDažnai (30–79%)1 ligoje
ARVCFARVCF delta catenin family memberDažnai (30–79%)1 ligoje
BLMBLM RecQ like helicaseDažnai (30–79%)2 ligose
BMP2bone morphogenetic protein 2Dažnai (30–79%)1 ligoje
CDH11cadherin 11Dažnai (30–79%)1 ligoje
CHD6chromodomain helicase DNA binding protein 6Dažnai (30–79%)1 ligoje
COL9A1collagen type IX alpha 1 chainDažnai (30–79%)1 ligoje
COL9A2collagen type IX alpha 2 chainDažnai (30–79%)1 ligoje
COL9A3collagen type IX alpha 3 chainDažnai (30–79%)1 ligoje
COMTcatechol-O-methyltransferaseDažnai (30–79%)1 ligoje
DLG3discs large MAGUK scaffold protein 3Dažnai (30–79%)1 ligoje
DVL1dishevelled segment polarity protein 1Dažnai (30–79%)1 ligoje
EHMT1euchromatic histone lysine methyltransferase 1Dažnai (30–79%)1 ligoje
FBN1fibrillin 1Dažnai (30–79%)2 ligose
FGFR3fibroblast growth factor receptor 3Dažnai (30–79%)5 ligose
FOXC1forkhead box C1Dažnai (30–79%)1 ligoje
FZD2frizzled class receptor 2Dažnai (30–79%)1 ligoje
GLI2GLI family zinc finger 2Dažnai (30–79%)1 ligoje
GP1BBglycoprotein Ib platelet subunit betaDažnai (30–79%)1 ligoje
GSCgoosecoid homeoboxDažnai (30–79%)1 ligoje
HBA1hemoglobin subunit alpha 1Dažnai (30–79%)1 ligoje
HBA2hemoglobin subunit alpha 2Dažnai (30–79%)1 ligoje
HIRAhistone cell cycle regulatorDažnai (30–79%)1 ligoje
IPO8importin 8Dažnai (30–79%)1 ligoje
JMJD1Cjumonji domain containing 1CDažnai (30–79%)1 ligoje
LOXL3lysyl oxidase like 3Dažnai (30–79%)1 ligoje
LRP4LDL receptor related protein 4Dažnai (30–79%)2 ligose
MBD5methyl-CpG binding domain protein 5Dažnai (30–79%)1 ligoje
MED12mediator complex subunit 12Dažnai (30–79%)1 ligoje
NEK1NIMA related kinase 1Dažnai (30–79%)1 ligoje
NGFnerve growth factorDažnai (30–79%)1 ligoje
NTRK1neurotrophic receptor tyrosine kinase 1Dažnai (30–79%)1 ligoje
PCGF2polycomb group ring finger 2Dažnai (30–79%)1 ligoje
PDZD8PDZ domain containing 8Dažnai (30–79%)1 ligoje
PIGAphosphatidylinositol glycan anchor biosynthesis class ADažnai (30–79%)1 ligoje
POLEDNA polymerase epsilon, catalytic subunitDažnai (30–79%)1 ligoje
PRMT7protein arginine methyltransferase 7Dažnai (30–79%)1 ligoje
RHOAras homolog family member ADažnai (30–79%)1 ligoje
RNU12RNA, U12 small nuclearDažnai (30–79%)2 ligose
RNU4ATACRNA, U4atac small nuclearDažnai (30–79%)1 ligoje
RPL17ribosomal protein L17Dažnai (30–79%)1 ligoje
RPS26ribosomal protein S26Dažnai (30–79%)1 ligoje
RREB1ras responsive element binding protein 1Dažnai (30–79%)1 ligoje
RUNX2RUNX family transcription factor 2Dažnai (30–79%)1 ligoje
SEC24CSEC24 homolog C, COPII componentDažnai (30–79%)1 ligoje
SETD2SET domain containing 2, histone lysine methyltransferaseDažnai (30–79%)2 ligose
SHANK3SH3 and multiple ankyrin repeat domains 3Dažnai (30–79%)1 ligoje
SLC2A10solute carrier family 2 member 10Dažnai (30–79%)2 ligose
SLC6A8solute carrier family 6 member 8Dažnai (30–79%)2 ligose
SMAD2SMAD family member 2Dažnai (30–79%)1 ligoje
SMAD3SMAD family member 3Dažnai (30–79%)3 ligose
STAG2STAG2 cohesin complex componentDažnai (30–79%)1 ligoje
TBX1T-box transcription factor 1Dažnai (30–79%)1 ligoje
TFE3transcription factor binding to IGHM enhancer 3Dažnai (30–79%)1 ligoje
TGFB2transforming growth factor beta 2Dažnai (30–79%)1 ligoje
TGFB3transforming growth factor beta 3Dažnai (30–79%)1 ligoje
TGFBR1transforming growth factor beta receptor 1Dažnai (30–79%)2 ligose
TGFBR2transforming growth factor beta receptor 2Dažnai (30–79%)2 ligose
TRIM33tripartite motif containing 33Dažnai (30–79%)1 ligoje
UBE2Aubiquitin conjugating enzyme E2 ADažnai (30–79%)1 ligoje
UFD1ubiquitin recognition factor in ER associated degradation 1Dažnai (30–79%)1 ligoje
WNT5AWnt family member 5ADažnai (30–79%)1 ligoje
APCAPC regulator of Wnt signaling pathwayKartais (5–29%)1 ligoje
ASXL3ASXL transcriptional regulator 3Kartais (5–29%)1 ligoje
BCRBCR activator of RhoGEF and GTPaseKartais (5–29%)1 ligoje
CDK10cyclin dependent kinase 10Kartais (5–29%)1 ligoje
CNOT3CCR4-NOT transcription complex subunit 3Kartais (5–29%)1 ligoje
COL5A1collagen type V alpha 1 chainKartais (5–29%)1 ligoje
CRELD1CRELD disulfide isomerase 1Kartais (5–29%)1 ligoje
CRKLCRK like proto-oncogene, adaptor proteinKartais (5–29%)1 ligoje
ELNelastinKartais (5–29%)1 ligoje
ERFETS2 repressor factorKartais (5–29%)1 ligoje
FAM50Afamily with sequence similarity 50 member AKartais (5–29%)1 ligoje
GORABgolgin, RAB6 interactingKartais (5–29%)2 ligose
GRIA3glutamate ionotropic receptor AMPA type subunit 3Kartais (5–29%)1 ligoje
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1Kartais (5–29%)2 ligose
KCNH1potassium voltage-gated channel subfamily H member 1Kartais (5–29%)1 ligoje
LTBP4latent transforming growth factor beta binding protein 4Kartais (5–29%)1 ligoje
MAN1B1mannosidase alpha class 1B member 1Kartais (5–29%)2 ligose
MAPK1mitogen-activated protein kinase 1Kartais (5–29%)1 ligoje
MLXIPLMLX interacting protein likeKartais (5–29%)1 ligoje
NDPnorrin cystine knot growth factor NDPKartais (5–29%)1 ligoje
NF1neurofibromin 1Kartais (5–29%)2 ligose
NPR3natriuretic peptide receptor 3Kartais (5–29%)1 ligoje
PIGTphosphatidylinositol glycan anchor biosynthesis class TKartais (5–29%)1 ligoje
PIK3R1phosphoinositide-3-kinase regulatory subunit 1Kartais (5–29%)1 ligoje
POGZpogo transposable element derived with ZNF domainKartais (5–29%)2 ligose
PYCR1pyrroline-5-carboxylate reductase 1Kartais (5–29%)2 ligose
RBM8ARNA binding motif protein 8AKartais (5–29%)1 ligoje
RFX7regulatory factor X7Kartais (5–29%)1 ligoje
TATtyrosine aminotransferaseKartais (5–29%)1 ligoje
TBX4T-box transcription factor 4Kartais (5–29%)1 ligoje
ZFXzinc finger protein X-linkedKartais (5–29%)1 ligoje
GJA5gap junction protein alpha 5Retai (1–4 %)1 ligoje
GJA8gap junction protein alpha 8Retai (1–4 %)1 ligoje
TP63tumor protein p63Retai (1–4 %)2 ligose
AGLamylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferaseNeužfiksuota1 ligoje
AIFM1apoptosis inducing factor mitochondria associated 1Neužfiksuota1 ligoje
ATRXATRX chromatin remodelerNeužfiksuota2 ligose
B3GALT6beta-1,3-galactosyltransferase 6Neužfiksuota1 ligoje
BUB1BBUB1 mitotic checkpoint serine/threonine kinase BNeužfiksuota1 ligoje
CCBE1collagen and calcium binding EGF domains 1Neužfiksuota1 ligoje
CHD7chromodomain helicase DNA binding protein 7Neužfiksuota1 ligoje
COL1A1collagen type I alpha 1 chainNeužfiksuota1 ligoje
CUL7cullin 7Neužfiksuota1 ligoje
DCHS1dachsous cadherin-related 1Neužfiksuota1 ligoje
DDR2discoidin domain receptor tyrosine kinase 2Neužfiksuota1 ligoje
DNMT3BDNA methyltransferase 3 betaNeužfiksuota1 ligoje
EBPEBP cholestenol delta-isomeraseNeužfiksuota1 ligoje
FAM20CFAM20C golgi associated secretory pathway kinaseNeužfiksuota1 ligoje
FAT4FAT atypical cadherin 4Neužfiksuota1 ligoje
GPC6glypican 6Neužfiksuota1 ligoje
HSPG2heparan sulfate proteoglycan 2Neužfiksuota2 ligose
KCNJ2potassium inwardly rectifying channel subfamily J member 2Neužfiksuota1 ligoje
KIF22kinesin family member 22Neužfiksuota1 ligoje
LIFRLIF receptor subunit alphaNeužfiksuota1 ligoje
LMNAlamin A/CNeužfiksuota1 ligoje
LRP2LDL receptor related protein 2Neužfiksuota1 ligoje
LRPPRCleucine rich pentatricopeptide repeat containingNeužfiksuota1 ligoje
MAFMAF bZIP transcription factorNeužfiksuota1 ligoje
MAN2B1mannosidase alpha class 2B member 1Neužfiksuota1 ligoje
MGPmatrix Gla proteinNeužfiksuota1 ligoje
MYH3myosin heavy chain 3Neužfiksuota1 ligoje
NECTIN1nectin cell adhesion molecule 1Neužfiksuota1 ligoje
PAX3paired box 3Neužfiksuota1 ligoje
PEX1peroxisomal biogenesis factor 1Neužfiksuota1 ligoje
PEX12peroxisomal biogenesis factor 12Neužfiksuota1 ligoje
PEX7peroxisomal biogenesis factor 7Neužfiksuota1 ligoje
PIGBphosphatidylinositol glycan anchor biosynthesis class BNeužfiksuota1 ligoje
PIGVphosphatidylinositol glycan anchor biosynthesis class VNeužfiksuota1 ligoje
POMGNT1protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)Neužfiksuota1 ligoje
PORcytochrome p450 oxidoreductaseNeužfiksuota2 ligose
POU1F1POU class 1 homeobox 1Neužfiksuota1 ligoje
PYCR2pyrroline-5-carboxylate reductase 2Neužfiksuota1 ligoje
RAB23RAB23, member RAS oncogene familyNeužfiksuota1 ligoje
RLIMring finger protein, LIM domain interactingNeužfiksuota1 ligoje
ROR2ROR family WNT receptor 2Neužfiksuota1 ligoje
SATB2SATB homeobox 2Neužfiksuota1 ligoje
SEC23ASEC23 homolog A, COPII componentNeužfiksuota1 ligoje
SERPINH1serpin family H member 1Neužfiksuota1 ligoje
SETBP1SET binding protein 1Neužfiksuota1 ligoje
SF3B2splicing factor 3b subunit 2Neužfiksuota1 ligoje
SHHsonic hedgehog signaling moleculeNeužfiksuota1 ligoje
SIX3SIX homeobox 3Neužfiksuota1 ligoje
SLC26A2solute carrier family 26 member 2Neužfiksuota2 ligose
SMAD4SMAD family member 4Neužfiksuota1 ligoje
SNRPBsmall nuclear ribonucleoprotein polypeptides B and B1Neužfiksuota1 ligoje
SOSTsclerostinNeužfiksuota1 ligoje
TFAP2Atranscription factor AP-2 alphaNeužfiksuota1 ligoje
TMEM237transmembrane protein 237Neužfiksuota1 ligoje
TONSLtonsoku like, DNA repair proteinNeužfiksuota1 ligoje
TWIST1twist family bHLH transcription factor 1Neužfiksuota2 ligose
ZBTB20zinc finger and BTB domain containing 20Neužfiksuota1 ligoje

Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.

Platesni požymiai

Abnormality of the cheekbone

Iš kur tai žinoma

  • Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
  • Duomenų leidimas 2026.10.19-9814e911.

From traits to your genome

Read the genes behind these traits in your own DNA.

The Genome Test sequences nearly all of your DNA, not a preset panel, so every gene on these pages is in your data. Premium adds 810+ physician-ready reports.

Nuo 449 $

Nemokamas pristatymas · Rezultatai per 6–8 savaites

Get my Genome TestSee the condition reports