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Egenskap
Mental deterioration
Loss of previously present mental abilities, generally in adults.
Sammendrag
- Også kalt
- Cognitive decline, Cognitive decline, progressive, Intellectual deterioration, Progressive cognitive decline
- Kroppssystem
- Abnormality of the nervous system
Mental deteriorationHP:0001268
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Read the genes linked to Mental deterioration, and the rest of your genome, with one test.
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Få mitt Genome Test189 gener knyttet til Mental deterioration
Endringer i disse genene forårsaker sjeldne tilstander der Mental deterioration forekommer. De fleste med denne egenskapen har ingen av disse tilstandene, og et gen på denne listen sier ingenting om noens eget genom.
| Gen | Hvor ofte den forekommer | Tilstander |
|---|---|---|
| AARS1alanyl-tRNA synthetase 1 | Alltid | I 2 tilstander |
| ARHGEF15Rho guanine nucleotide exchange factor 15 | Alltid | I 1 tilstand |
| ATP13A2ATPase cation transporting 13A2 | Alltid | I 2 tilstander |
| CARS2cysteinyl-tRNA synthetase 2, mitochondrial | Alltid | I 1 tilstand |
| CLN6CLN6 transmembrane ER protein | Alltid | I 1 tilstand |
| COX6B1cytochrome c oxidase subunit 6B1 | Alltid | I 1 tilstand |
| CTSAcathepsin A | Alltid | I 1 tilstand |
| CTSDcathepsin D | Alltid | I 1 tilstand |
| CTSFcathepsin F | Alltid | I 1 tilstand |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Alltid | I 1 tilstand |
| FMR1fragile X messenger ribonucleoprotein 1 | Alltid | I 1 tilstand |
| FUCA1alpha-L-fucosidase 1 | Alltid | I 1 tilstand |
| KARS1lysyl-tRNA synthetase 1 | Alltid | I 1 tilstand |
| PLA2G6phospholipase A2 group VI | Alltid | I 3 tilstander |
| PLP1proteolipid protein 1 | Alltid | I 2 tilstander |
| POLR3KRNA polymerase III subunit K | Alltid | I 1 tilstand |
| RPS6KC1ribosomal protein S6 kinase C1 | Alltid | I 1 tilstand |
| STUB1STIP1 homology and U-box containing protein 1 | Alltid | I 1 tilstand |
| TSPOAP1TSPO associated protein 1 | Alltid | I 2 tilstander |
| VPS13Cvacuolar protein sorting 13 homolog C | Alltid | I 1 tilstand |
| WDR45WD repeat domain 45 | Alltid | I 1 tilstand |
| XPAXPA, DNA damage recognition and repair factor | Alltid | I 1 tilstand |
| ABCD1ATP binding cassette subfamily D member 1 | Svært ofte (80–99 %) | I 2 tilstander |
| ACTBactin beta | Svært ofte (80–99 %) | I 1 tilstand |
| APPamyloid beta precursor protein | Svært ofte (80–99 %) | I 2 tilstander |
| CHMP2Bcharged multivesicular body protein 2B | Svært ofte (80–99 %) | I 2 tilstander |
| DCAF17DDB1 and CUL4 associated factor 17 | Svært ofte (80–99 %) | I 1 tilstand |
| FA2Hfatty acid 2-hydroxylase | Svært ofte (80–99 %) | I 3 tilstander |
| GALCgalactosylceramidase | Svært ofte (80–99 %) | I 3 tilstander |
| GRNgranulin precursor | Svært ofte (80–99 %) | I 3 tilstander |
| HEPACAMhepatic and glial cell adhesion molecule | Svært ofte (80–99 %) | I 2 tilstander |
| HTThuntingtin | Svært ofte (80–99 %) | I 1 tilstand |
| MAPTmicrotubule associated protein tau | Svært ofte (80–99 %) | I 6 tilstander |
| NBNnibrin | Svært ofte (80–99 %) | I 1 tilstand |
| PSAPprosaposin | Svært ofte (80–99 %) | I 2 tilstander |
| PSEN1presenilin 1 | Svært ofte (80–99 %) | I 2 tilstander |
| ROGDIrogdi atypical leucine zipper | Svært ofte (80–99 %) | I 1 tilstand |
| SLC13A5solute carrier family 13 member 5 | Svært ofte (80–99 %) | I 2 tilstander |
| SLC2A3solute carrier family 2 member 3 | Svært ofte (80–99 %) | I 1 tilstand |
| SLC44A1solute carrier family 44 member 1 | Svært ofte (80–99 %) | I 1 tilstand |
Vis 149 gener til
| Gen | Hvor ofte den forekommer | Tilstander |
|---|---|---|
| SPG11SPG11 vesicle trafficking associated, spatacsin | Svært ofte (80–99 %) | I 2 tilstander |
| SQSTM1sequestosome 1 | Svært ofte (80–99 %) | I 2 tilstander |
| TMEM106Btransmembrane protein 106B | Svært ofte (80–99 %) | I 2 tilstander |
| TREM2triggering receptor expressed on myeloid cells 2 | Svært ofte (80–99 %) | I 2 tilstander |
| VCPvalosin containing protein | Svært ofte (80–99 %) | I 2 tilstander |
| ADA2adenosine deaminase 2 | Ofte (30–79 %) | I 2 tilstander |
| AGKacylglycerol kinase | Ofte (30–79 %) | I 1 tilstand |
| AQP4aquaporin 4 | Ofte (30–79 %) | I 1 tilstand |
| ATXN7ataxin 7 | Ofte (30–79 %) | I 2 tilstander |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Ofte (30–79 %) | I 2 tilstander |
| CHD2chromodomain helicase DNA binding protein 2 | Ofte (30–79 %) | I 1 tilstand |
| CNTNAP2contactin associated protein 2 | Ofte (30–79 %) | I 1 tilstand |
| CPLX1complexin 1 | Ofte (30–79 %) | I 1 tilstand |
| CST3cystatin C | Ofte (30–79 %) | I 1 tilstand |
| CSTBcystatin B | Ofte (30–79 %) | I 1 tilstand |
| CUX2cut like homeobox 2 | Ofte (30–79 %) | I 1 tilstand |
| DNM1dynamin 1 | Ofte (30–79 %) | I 2 tilstander |
| EPG5ectopic P-granules 5 autophagy tethering factor | Ofte (30–79 %) | I 1 tilstand |
| EPM2AEPM2A glucan phosphatase, laforin | Ofte (30–79 %) | I 1 tilstand |
| FTH1ferritin heavy chain 1 | Ofte (30–79 %) | I 1 tilstand |
| GABRB3gamma-aminobutyric acid type A receptor subunit beta3 | Ofte (30–79 %) | I 1 tilstand |
| GALTgalactose-1-phosphate uridylyltransferase | Ofte (30–79 %) | I 1 tilstand |
| GDAP2ganglioside induced differentiation associated protein 2 | Ofte (30–79 %) | I 1 tilstand |
| GOSR2golgi SNAP receptor complex member 2 | Ofte (30–79 %) | I 1 tilstand |
| GPRC5BG protein-coupled receptor class C group 5 member B | Ofte (30–79 %) | I 1 tilstand |
| HEXBhexosaminidase subunit beta | Ofte (30–79 %) | I 1 tilstand |
| HMBShydroxymethylbilane synthase | Ofte (30–79 %) | I 1 tilstand |
| JAM2junctional adhesion molecule 2 | Ofte (30–79 %) | I 2 tilstander |
| KCNC1potassium voltage-gated channel subfamily C member 1 | Ofte (30–79 %) | I 1 tilstand |
| MAPK10mitogen-activated protein kinase 10 | Ofte (30–79 %) | I 1 tilstand |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Ofte (30–79 %) | I 1 tilstand |
| MLC1modulator of VRAC current 1 | Ofte (30–79 %) | I 1 tilstand |
| MT-TKmitochondrially encoded tRNA-Lys (AAA/G) | Ofte (30–79 %) | I 1 tilstand |
| MTHFRmethylenetetrahydrofolate reductase | Ofte (30–79 %) | I 1 tilstand |
| NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1 | Ofte (30–79 %) | I 1 tilstand |
| PANK2pantothenate kinase 2 | Ofte (30–79 %) | I 1 tilstand |
| PRNPprion protein (Kanno blood group) | Ofte (30–79 %) | I 2 tilstander |
| RRP12ribosomal RNA processing 12 homolog | Ofte (30–79 %) | I 1 tilstand |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Ofte (30–79 %) | I 3 tilstander |
| SCN8Asodium voltage-gated channel alpha subunit 8 | Ofte (30–79 %) | I 2 tilstander |
| SLC7A6OSsolute carrier family 7 member 6 opposite strand | Ofte (30–79 %) | I 1 tilstand |
| SLC9A6solute carrier family 9 member A6 | Ofte (30–79 %) | I 1 tilstand |
| SMPD1sphingomyelin phosphodiesterase 1 | Ofte (30–79 %) | I 1 tilstand |
| SNORD118small nucleolar RNA, C/D box 118 | Ofte (30–79 %) | I 2 tilstander |
| SPG21SPG21 abhydrolase domain containing, maspardin | Ofte (30–79 %) | I 1 tilstand |
| SYNJ1synaptojanin 1 | Ofte (30–79 %) | I 2 tilstander |
| TBC1D24TBC1 domain family member 24 | Ofte (30–79 %) | I 1 tilstand |
| TBPTATA-box binding protein | Ofte (30–79 %) | I 1 tilstand |
| TIMM8Atranslocase of inner mitochondrial membrane 8A | Ofte (30–79 %) | I 2 tilstander |
| TMEM240transmembrane protein 240 | Ofte (30–79 %) | I 1 tilstand |
| AASSaminoadipate-semialdehyde synthase | Noen ganger (5–29 %) | I 1 tilstand |
| ACTL6Bactin like 6B | Noen ganger (5–29 %) | I 1 tilstand |
| AMACRalpha-methylacyl-CoA racemase | Noen ganger (5–29 %) | I 1 tilstand |
| AP3B2adaptor related protein complex 3 subunit beta 2 | Noen ganger (5–29 %) | I 1 tilstand |
| APTXaprataxin | Noen ganger (5–29 %) | I 1 tilstand |
| ASAH1N-acylsphingosine amidohydrolase 1 | Noen ganger (5–29 %) | I 1 tilstand |
| ATP1A2ATPase Na+/K+ transporting subunit alpha 2 | Noen ganger (5–29 %) | I 1 tilstand |
| ATP1A3ATPase Na+/K+ transporting subunit alpha 3 | Noen ganger (5–29 %) | I 2 tilstander |
| ATP6V1AATPase H+ transporting V1 subunit A | Noen ganger (5–29 %) | I 1 tilstand |
| CACNA1Bcalcium voltage-gated channel subunit alpha1 B | Noen ganger (5–29 %) | I 1 tilstand |
| CACNA2D1calcium voltage-gated channel auxiliary subunit alpha2delta 1 | Noen ganger (5–29 %) | I 1 tilstand |
| CDK19cyclin dependent kinase 19 | Noen ganger (5–29 %) | I 1 tilstand |
| CELF2CUGBP Elav-like family member 2 | Noen ganger (5–29 %) | I 1 tilstand |
| CLTCclathrin heavy chain | Noen ganger (5–29 %) | I 1 tilstand |
| CNKSR2connector enhancer of kinase suppressor of Ras 2 | Noen ganger (5–29 %) | I 1 tilstand |
| CYFIP2cytoplasmic FMR1 interacting protein 2 | Noen ganger (5–29 %) | I 1 tilstand |
| DALRD3DALR anticodon binding domain containing 3 | Noen ganger (5–29 %) | I 1 tilstand |
| DARS2aspartyl-tRNA synthetase 2, mitochondrial | Noen ganger (5–29 %) | I 1 tilstand |
| DEPDC5DEP domain containing 5, GATOR1 subcomplex subunit | Noen ganger (5–29 %) | I 1 tilstand |
| DHDDSdehydrodolichyl diphosphate synthase subunit | Noen ganger (5–29 %) | I 1 tilstand |
| DNAJC13DnaJ heat shock protein family (Hsp40) member C13 | Noen ganger (5–29 %) | I 1 tilstand |
| DNMT1DNA methyltransferase 1 | Noen ganger (5–29 %) | I 1 tilstand |
| EEF1A2eukaryotic translation elongation factor 1 alpha 2 | Noen ganger (5–29 %) | I 1 tilstand |
| EIF4G1eukaryotic translation initiation factor 4 gamma 1 | Noen ganger (5–29 %) | I 1 tilstand |
| FBXO28F-box protein 28 | Noen ganger (5–29 %) | I 1 tilstand |
| FGF12fibroblast growth factor 12 | Noen ganger (5–29 %) | I 1 tilstand |
| FOXG1forkhead box G1 | Noen ganger (5–29 %) | I 1 tilstand |
| FZR1fizzy and cell division cycle 20 related 1 | Noen ganger (5–29 %) | I 1 tilstand |
| GABBR2gamma-aminobutyric acid type B receptor subunit 2 | Noen ganger (5–29 %) | I 1 tilstand |
| GABRA2gamma-aminobutyric acid type A receptor subunit alpha2 | Noen ganger (5–29 %) | I 1 tilstand |
| GABRA5gamma-aminobutyric acid type A receptor subunit alpha5 | Noen ganger (5–29 %) | I 1 tilstand |
| GABRB2gamma-aminobutyric acid type A receptor subunit beta2 | Noen ganger (5–29 %) | I 1 tilstand |
| GABRG2gamma-aminobutyric acid type A receptor subunit gamma2 | Noen ganger (5–29 %) | I 1 tilstand |
| GBA1glucosylceramidase beta 1 | Noen ganger (5–29 %) | I 1 tilstand |
| GIGYF2GRB10 interacting GYF protein 2 | Noen ganger (5–29 %) | I 1 tilstand |
| GRIN2Dglutamate ionotropic receptor NMDA type subunit 2D | Noen ganger (5–29 %) | I 1 tilstand |
| HCN1hyperpolarization activated cyclic nucleotide gated potassium channel 1 | Noen ganger (5–29 %) | I 1 tilstand |
| HTRA1HtrA serine peptidase 1 | Noen ganger (5–29 %) | I 2 tilstander |
| KCNA2potassium voltage-gated channel subfamily A member 2 | Noen ganger (5–29 %) | I 1 tilstand |
| KCNB1potassium voltage-gated channel subfamily B member 1 | Noen ganger (5–29 %) | I 1 tilstand |
| KCNC2potassium voltage-gated channel subfamily C member 2 | Noen ganger (5–29 %) | I 1 tilstand |
| KCNH5potassium voltage-gated channel subfamily H member 5 | Noen ganger (5–29 %) | I 1 tilstand |
| L1CAML1 cell adhesion molecule | Noen ganger (5–29 %) | I 1 tilstand |
| LIG3DNA ligase 3 | Noen ganger (5–29 %) | I 1 tilstand |
| LRRK2leucine rich repeat kinase 2 | Noen ganger (5–29 %) | I 1 tilstand |
| MAP2K1mitogen-activated protein kinase kinase 1 | Noen ganger (5–29 %) | I 1 tilstand |
| MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2 | Noen ganger (5–29 %) | I 1 tilstand |
| MFN2mitofusin 2 | Noen ganger (5–29 %) | I 1 tilstand |
| MMACHCmetabolism of cobalamin associated C | Noen ganger (5–29 %) | I 1 tilstand |
| MYORGmyogenesis regulating glycosidase | Noen ganger (5–29 %) | I 2 tilstander |
| NECAP1NECAP endocytosis associated 1 | Noen ganger (5–29 %) | I 1 tilstand |
| NRASNRAS proto-oncogene, GTPase | Noen ganger (5–29 %) | I 2 tilstander |
| NTRK2neurotrophic receptor tyrosine kinase 2 | Noen ganger (5–29 %) | I 1 tilstand |
| NUS1NUS1 dehydrodolichyl diphosphate synthase subunit | Noen ganger (5–29 %) | I 1 tilstand |
| PACS2phosphofurin acidic cluster sorting protein 2 | Noen ganger (5–29 %) | I 1 tilstand |
| PARS2prolyl-tRNA synthetase 2, mitochondrial | Noen ganger (5–29 %) | I 1 tilstand |
| PPP3CAprotein phosphatase 3 catalytic subunit alpha | Noen ganger (5–29 %) | I 1 tilstand |
| PRDM8PR/SET domain 8 | Noen ganger (5–29 %) | I 1 tilstand |
| SCN3Asodium voltage-gated channel alpha subunit 3 | Noen ganger (5–29 %) | I 1 tilstand |
| SLC1A2solute carrier family 1 member 2 | Noen ganger (5–29 %) | I 1 tilstand |
| SLC38A3solute carrier family 38 member 3 | Noen ganger (5–29 %) | I 1 tilstand |
| SNCAsynuclein alpha | Noen ganger (5–29 %) | I 2 tilstander |
| SYNGAP1synaptic Ras GTPase activating protein 1 | Noen ganger (5–29 %) | I 1 tilstand |
| SZT2SZT2 subunit of KICSTOR complex | Noen ganger (5–29 %) | I 1 tilstand |
| TRAK1trafficking kinesin protein 1 | Noen ganger (5–29 %) | I 1 tilstand |
| TTPAalpha tocopherol transfer protein | Noen ganger (5–29 %) | I 1 tilstand |
| UBA5ubiquitin like modifier activating enzyme 5 | Noen ganger (5–29 %) | I 1 tilstand |
| UBAP1ubiquitin associated protein 1 | Noen ganger (5–29 %) | I 1 tilstand |
| UFSP2UFM1 specific peptidase 2 | Noen ganger (5–29 %) | I 1 tilstand |
| VPS13Avacuolar protein sorting 13 homolog A | Noen ganger (5–29 %) | I 1 tilstand |
| VPS35VPS35 retromer complex component | Noen ganger (5–29 %) | I 1 tilstand |
| YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma | Noen ganger (5–29 %) | I 1 tilstand |
| KCNQ2potassium voltage-gated channel subfamily Q member 2 | Sjelden (1–4%) | I 1 tilstand |
| SCN2Asodium voltage-gated channel alpha subunit 2 | Sjelden (1–4%) | I 1 tilstand |
| TLR3toll like receptor 3 | Sjelden (1–4%) | I 1 tilstand |
| AP5Z1adaptor related protein complex 5 subunit zeta 1 | Ikke registrert | I 1 tilstand |
| ARSAarylsulfatase A | Ikke registrert | I 1 tilstand |
| BSCL2BSCL2 lipid droplet biogenesis associated, seipin | Ikke registrert | I 1 tilstand |
| C19orf12chromosome 19 open reading frame 12 | Ikke registrert | I 1 tilstand |
| CLN8CLN8 transmembrane ER and ERGIC protein | Ikke registrert | I 1 tilstand |
| COASYCoenzyme A synthase | Ikke registrert | I 1 tilstand |
| CSF1Rcolony stimulating factor 1 receptor | Ikke registrert | I 2 tilstander |
| CTC1CST telomere replication complex component 1 | Ikke registrert | I 1 tilstand |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Ikke registrert | I 1 tilstand |
| GBA2glucosylceramidase beta 2 | Ikke registrert | I 1 tilstand |
| GNASGNAS complex locus | Ikke registrert | I 1 tilstand |
| MFSD8major facilitator superfamily domain containing 8 | Ikke registrert | I 1 tilstand |
| NAA60N-alpha-acetyltransferase 60, NatF catalytic subunit | Ikke registrert | I 1 tilstand |
| PDE10Aphosphodiesterase 10A | Ikke registrert | I 1 tilstand |
| PDE11Aphosphodiesterase 11A | Ikke registrert | I 1 tilstand |
| PDGFBplatelet derived growth factor subunit B | Ikke registrert | I 1 tilstand |
| PDGFRBplatelet derived growth factor receptor beta | Ikke registrert | I 1 tilstand |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Ikke registrert | I 1 tilstand |
| PRKCGprotein kinase C gamma | Ikke registrert | I 1 tilstand |
| SGPL1sphingosine-1-phosphate lyase 1 | Ikke registrert | I 1 tilstand |
| SLC20A2solute carrier family 20 member 2 | Ikke registrert | I 1 tilstand |
| TBK1TANK binding kinase 1 | Ikke registrert | I 1 tilstand |
| UBTFupstream binding transcription factor | Ikke registrert | I 1 tilstand |
| XPR1xenotropic and polytropic retrovirus receptor 1 | Ikke registrert | I 1 tilstand |
Hvor ofte dette forekommer hos personer med en av genets tilstander, oppgitt som den hyppigste forekomsten blant dem, slik Human Phenotype Ontology registrerer den. Disse sidene beskriver egenskaper og forskningen bak dem. De er ikke en diagnose, og om symptomer bør du spørre lege eller genetisk rådgiver.
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Slik er informasjonen samlet
- Human Phenotype Ontology, versjon 2026-09-01: egenskapen, navnene på den, definisjonen og genene som er knyttet til den. Les mer på hpo.jax.org.
- Datautgave 2026.10.16-c6eea6bf.
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Fra 449 $Gratis frakt · Resultater på 6–8 uker