Træk
Mental deterioration
Loss of previously present mental abilities, generally in adults.
Resumé
- Også kaldet
- Cognitive decline, Cognitive decline, progressive, Intellectual deterioration, Progressive cognitive decline
- Kropssystem
- Abnormality of the nervous system
ReferencegenomGRCh38hg38
Positioner på gen- og variantsider følger dette valg i denne browser.
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Bestil min Genome Test189 gener knyttet til Mental deterioration
Ændringer i disse gener forårsager sjældne tilstande, hvor Mental deterioration ses. De fleste med dette træk har ingen af disse tilstande, og et gen på denne liste siger intet om nogens eget genom.
| Gen | Hvor ofte det ses | Tilstande |
|---|---|---|
| AARS1alanyl-tRNA synthetase 1 | Altid | I 2 tilstande |
| ARHGEF15Rho guanine nucleotide exchange factor 15 | Altid | I 1 tilstand |
| ATP13A2ATPase cation transporting 13A2 | Altid | I 2 tilstande |
| CARS2cysteinyl-tRNA synthetase 2, mitochondrial | Altid | I 1 tilstand |
| CLN6CLN6 transmembrane ER protein | Altid | I 1 tilstand |
| COX6B1cytochrome c oxidase subunit 6B1 | Altid | I 1 tilstand |
| CTSAcathepsin A | Altid | I 1 tilstand |
| CTSDcathepsin D | Altid | I 1 tilstand |
| CTSFcathepsin F | Altid | I 1 tilstand |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Altid | I 1 tilstand |
| FMR1fragile X messenger ribonucleoprotein 1 | Altid | I 1 tilstand |
| FUCA1alpha-L-fucosidase 1 | Altid | I 1 tilstand |
| KARS1lysyl-tRNA synthetase 1 | Altid | I 1 tilstand |
| PLA2G6phospholipase A2 group VI | Altid | I 3 tilstande |
| PLP1proteolipid protein 1 | Altid | I 2 tilstande |
| POLR3KRNA polymerase III subunit K | Altid | I 1 tilstand |
| RPS6KC1ribosomal protein S6 kinase C1 | Altid | I 1 tilstand |
| STUB1STIP1 homology and U-box containing protein 1 | Altid | I 1 tilstand |
| TSPOAP1TSPO associated protein 1 | Altid | I 2 tilstande |
| VPS13Cvacuolar protein sorting 13 homolog C | Altid | I 1 tilstand |
| WDR45WD repeat domain 45 | Altid | I 1 tilstand |
| XPAXPA, DNA damage recognition and repair factor | Altid | I 1 tilstand |
| ABCD1ATP binding cassette subfamily D member 1 | Meget ofte (80–99 %) | I 2 tilstande |
| ACTBactin beta | Meget ofte (80–99 %) | I 1 tilstand |
| APPamyloid beta precursor protein | Meget ofte (80–99 %) | I 2 tilstande |
| CHMP2Bcharged multivesicular body protein 2B | Meget ofte (80–99 %) | I 2 tilstande |
| DCAF17DDB1 and CUL4 associated factor 17 | Meget ofte (80–99 %) | I 1 tilstand |
| FA2Hfatty acid 2-hydroxylase | Meget ofte (80–99 %) | I 3 tilstande |
| GALCgalactosylceramidase | Meget ofte (80–99 %) | I 3 tilstande |
| GRNgranulin precursor | Meget ofte (80–99 %) | I 3 tilstande |
| HEPACAMhepatic and glial cell adhesion molecule | Meget ofte (80–99 %) | I 2 tilstande |
| HTThuntingtin | Meget ofte (80–99 %) | I 1 tilstand |
| MAPTmicrotubule associated protein tau | Meget ofte (80–99 %) | I 6 tilstande |
| NBNnibrin | Meget ofte (80–99 %) | I 1 tilstand |
| PSAPprosaposin | Meget ofte (80–99 %) | I 2 tilstande |
| PSEN1presenilin 1 | Meget ofte (80–99 %) | I 2 tilstande |
| ROGDIrogdi atypical leucine zipper | Meget ofte (80–99 %) | I 1 tilstand |
| SLC13A5solute carrier family 13 member 5 | Meget ofte (80–99 %) | I 2 tilstande |
| SLC2A3solute carrier family 2 member 3 | Meget ofte (80–99 %) | I 1 tilstand |
| SLC44A1solute carrier family 44 member 1 | Meget ofte (80–99 %) | I 1 tilstand |
Vis 149 gener mere
| Gen | Hvor ofte det ses | Tilstande |
|---|---|---|
| SPG11SPG11 vesicle trafficking associated, spatacsin | Meget ofte (80–99 %) | I 2 tilstande |
| SQSTM1sequestosome 1 | Meget ofte (80–99 %) | I 2 tilstande |
| TMEM106Btransmembrane protein 106B | Meget ofte (80–99 %) | I 2 tilstande |
| TREM2triggering receptor expressed on myeloid cells 2 | Meget ofte (80–99 %) | I 2 tilstande |
| VCPvalosin containing protein | Meget ofte (80–99 %) | I 2 tilstande |
| ADA2adenosine deaminase 2 | Ofte (30–79 %) | I 2 tilstande |
| AGKacylglycerol kinase | Ofte (30–79 %) | I 1 tilstand |
| AQP4aquaporin 4 | Ofte (30–79 %) | I 1 tilstand |
| ATXN7ataxin 7 | Ofte (30–79 %) | I 2 tilstande |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Ofte (30–79 %) | I 2 tilstande |
| CHD2chromodomain helicase DNA binding protein 2 | Ofte (30–79 %) | I 1 tilstand |
| CNTNAP2contactin associated protein 2 | Ofte (30–79 %) | I 1 tilstand |
| CPLX1complexin 1 | Ofte (30–79 %) | I 1 tilstand |
| CST3cystatin C | Ofte (30–79 %) | I 1 tilstand |
| CSTBcystatin B | Ofte (30–79 %) | I 1 tilstand |
| CUX2cut like homeobox 2 | Ofte (30–79 %) | I 1 tilstand |
| DNM1dynamin 1 | Ofte (30–79 %) | I 2 tilstande |
| EPG5ectopic P-granules 5 autophagy tethering factor | Ofte (30–79 %) | I 1 tilstand |
| EPM2AEPM2A glucan phosphatase, laforin | Ofte (30–79 %) | I 1 tilstand |
| FTH1ferritin heavy chain 1 | Ofte (30–79 %) | I 1 tilstand |
| GABRB3gamma-aminobutyric acid type A receptor subunit beta3 | Ofte (30–79 %) | I 1 tilstand |
| GALTgalactose-1-phosphate uridylyltransferase | Ofte (30–79 %) | I 1 tilstand |
| GDAP2ganglioside induced differentiation associated protein 2 | Ofte (30–79 %) | I 1 tilstand |
| GOSR2golgi SNAP receptor complex member 2 | Ofte (30–79 %) | I 1 tilstand |
| GPRC5BG protein-coupled receptor class C group 5 member B | Ofte (30–79 %) | I 1 tilstand |
| HEXBhexosaminidase subunit beta | Ofte (30–79 %) | I 1 tilstand |
| HMBShydroxymethylbilane synthase | Ofte (30–79 %) | I 1 tilstand |
| JAM2junctional adhesion molecule 2 | Ofte (30–79 %) | I 2 tilstande |
| KCNC1potassium voltage-gated channel subfamily C member 1 | Ofte (30–79 %) | I 1 tilstand |
| MAPK10mitogen-activated protein kinase 10 | Ofte (30–79 %) | I 1 tilstand |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Ofte (30–79 %) | I 1 tilstand |
| MLC1modulator of VRAC current 1 | Ofte (30–79 %) | I 1 tilstand |
| MT-TKmitochondrially encoded tRNA-Lys (AAA/G) | Ofte (30–79 %) | I 1 tilstand |
| MTHFRmethylenetetrahydrofolate reductase | Ofte (30–79 %) | I 1 tilstand |
| NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1 | Ofte (30–79 %) | I 1 tilstand |
| PANK2pantothenate kinase 2 | Ofte (30–79 %) | I 1 tilstand |
| PRNPprion protein (Kanno blood group) | Ofte (30–79 %) | I 2 tilstande |
| RRP12ribosomal RNA processing 12 homolog | Ofte (30–79 %) | I 1 tilstand |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Ofte (30–79 %) | I 3 tilstande |
| SCN8Asodium voltage-gated channel alpha subunit 8 | Ofte (30–79 %) | I 2 tilstande |
| SLC7A6OSsolute carrier family 7 member 6 opposite strand | Ofte (30–79 %) | I 1 tilstand |
| SLC9A6solute carrier family 9 member A6 | Ofte (30–79 %) | I 1 tilstand |
| SMPD1sphingomyelin phosphodiesterase 1 | Ofte (30–79 %) | I 1 tilstand |
| SNORD118small nucleolar RNA, C/D box 118 | Ofte (30–79 %) | I 2 tilstande |
| SPG21SPG21 abhydrolase domain containing, maspardin | Ofte (30–79 %) | I 1 tilstand |
| SYNJ1synaptojanin 1 | Ofte (30–79 %) | I 2 tilstande |
| TBC1D24TBC1 domain family member 24 | Ofte (30–79 %) | I 1 tilstand |
| TBPTATA-box binding protein | Ofte (30–79 %) | I 1 tilstand |
| TIMM8Atranslocase of inner mitochondrial membrane 8A | Ofte (30–79 %) | I 2 tilstande |
| TMEM240transmembrane protein 240 | Ofte (30–79 %) | I 1 tilstand |
| AASSaminoadipate-semialdehyde synthase | Nogle gange (5–29 %) | I 1 tilstand |
| ACTL6Bactin like 6B | Nogle gange (5–29 %) | I 1 tilstand |
| AMACRalpha-methylacyl-CoA racemase | Nogle gange (5–29 %) | I 1 tilstand |
| AP3B2adaptor related protein complex 3 subunit beta 2 | Nogle gange (5–29 %) | I 1 tilstand |
| APTXaprataxin | Nogle gange (5–29 %) | I 1 tilstand |
| ASAH1N-acylsphingosine amidohydrolase 1 | Nogle gange (5–29 %) | I 1 tilstand |
| ATP1A2ATPase Na+/K+ transporting subunit alpha 2 | Nogle gange (5–29 %) | I 1 tilstand |
| ATP1A3ATPase Na+/K+ transporting subunit alpha 3 | Nogle gange (5–29 %) | I 2 tilstande |
| ATP6V1AATPase H+ transporting V1 subunit A | Nogle gange (5–29 %) | I 1 tilstand |
| CACNA1Bcalcium voltage-gated channel subunit alpha1 B | Nogle gange (5–29 %) | I 1 tilstand |
| CACNA2D1calcium voltage-gated channel auxiliary subunit alpha2delta 1 | Nogle gange (5–29 %) | I 1 tilstand |
| CDK19cyclin dependent kinase 19 | Nogle gange (5–29 %) | I 1 tilstand |
| CELF2CUGBP Elav-like family member 2 | Nogle gange (5–29 %) | I 1 tilstand |
| CLTCclathrin heavy chain | Nogle gange (5–29 %) | I 1 tilstand |
| CNKSR2connector enhancer of kinase suppressor of Ras 2 | Nogle gange (5–29 %) | I 1 tilstand |
| CYFIP2cytoplasmic FMR1 interacting protein 2 | Nogle gange (5–29 %) | I 1 tilstand |
| DALRD3DALR anticodon binding domain containing 3 | Nogle gange (5–29 %) | I 1 tilstand |
| DARS2aspartyl-tRNA synthetase 2, mitochondrial | Nogle gange (5–29 %) | I 1 tilstand |
| DEPDC5DEP domain containing 5, GATOR1 subcomplex subunit | Nogle gange (5–29 %) | I 1 tilstand |
| DHDDSdehydrodolichyl diphosphate synthase subunit | Nogle gange (5–29 %) | I 1 tilstand |
| DNAJC13DnaJ heat shock protein family (Hsp40) member C13 | Nogle gange (5–29 %) | I 1 tilstand |
| DNMT1DNA methyltransferase 1 | Nogle gange (5–29 %) | I 1 tilstand |
| EEF1A2eukaryotic translation elongation factor 1 alpha 2 | Nogle gange (5–29 %) | I 1 tilstand |
| EIF4G1eukaryotic translation initiation factor 4 gamma 1 | Nogle gange (5–29 %) | I 1 tilstand |
| FBXO28F-box protein 28 | Nogle gange (5–29 %) | I 1 tilstand |
| FGF12fibroblast growth factor 12 | Nogle gange (5–29 %) | I 1 tilstand |
| FOXG1forkhead box G1 | Nogle gange (5–29 %) | I 1 tilstand |
| FZR1fizzy and cell division cycle 20 related 1 | Nogle gange (5–29 %) | I 1 tilstand |
| GABBR2gamma-aminobutyric acid type B receptor subunit 2 | Nogle gange (5–29 %) | I 1 tilstand |
| GABRA2gamma-aminobutyric acid type A receptor subunit alpha2 | Nogle gange (5–29 %) | I 1 tilstand |
| GABRA5gamma-aminobutyric acid type A receptor subunit alpha5 | Nogle gange (5–29 %) | I 1 tilstand |
| GABRB2gamma-aminobutyric acid type A receptor subunit beta2 | Nogle gange (5–29 %) | I 1 tilstand |
| GABRG2gamma-aminobutyric acid type A receptor subunit gamma2 | Nogle gange (5–29 %) | I 1 tilstand |
| GBA1glucosylceramidase beta 1 | Nogle gange (5–29 %) | I 1 tilstand |
| GIGYF2GRB10 interacting GYF protein 2 | Nogle gange (5–29 %) | I 1 tilstand |
| GRIN2Dglutamate ionotropic receptor NMDA type subunit 2D | Nogle gange (5–29 %) | I 1 tilstand |
| HCN1hyperpolarization activated cyclic nucleotide gated potassium channel 1 | Nogle gange (5–29 %) | I 1 tilstand |
| HTRA1HtrA serine peptidase 1 | Nogle gange (5–29 %) | I 2 tilstande |
| KCNA2potassium voltage-gated channel subfamily A member 2 | Nogle gange (5–29 %) | I 1 tilstand |
| KCNB1potassium voltage-gated channel subfamily B member 1 | Nogle gange (5–29 %) | I 1 tilstand |
| KCNC2potassium voltage-gated channel subfamily C member 2 | Nogle gange (5–29 %) | I 1 tilstand |
| KCNH5potassium voltage-gated channel subfamily H member 5 | Nogle gange (5–29 %) | I 1 tilstand |
| L1CAML1 cell adhesion molecule | Nogle gange (5–29 %) | I 1 tilstand |
| LIG3DNA ligase 3 | Nogle gange (5–29 %) | I 1 tilstand |
| LRRK2leucine rich repeat kinase 2 | Nogle gange (5–29 %) | I 1 tilstand |
| MAP2K1mitogen-activated protein kinase kinase 1 | Nogle gange (5–29 %) | I 1 tilstand |
| MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2 | Nogle gange (5–29 %) | I 1 tilstand |
| MFN2mitofusin 2 | Nogle gange (5–29 %) | I 1 tilstand |
| MMACHCmetabolism of cobalamin associated C | Nogle gange (5–29 %) | I 1 tilstand |
| MYORGmyogenesis regulating glycosidase | Nogle gange (5–29 %) | I 2 tilstande |
| NECAP1NECAP endocytosis associated 1 | Nogle gange (5–29 %) | I 1 tilstand |
| NRASNRAS proto-oncogene, GTPase | Nogle gange (5–29 %) | I 2 tilstande |
| NTRK2neurotrophic receptor tyrosine kinase 2 | Nogle gange (5–29 %) | I 1 tilstand |
| NUS1NUS1 dehydrodolichyl diphosphate synthase subunit | Nogle gange (5–29 %) | I 1 tilstand |
| PACS2phosphofurin acidic cluster sorting protein 2 | Nogle gange (5–29 %) | I 1 tilstand |
| PARS2prolyl-tRNA synthetase 2, mitochondrial | Nogle gange (5–29 %) | I 1 tilstand |
| PPP3CAprotein phosphatase 3 catalytic subunit alpha | Nogle gange (5–29 %) | I 1 tilstand |
| PRDM8PR/SET domain 8 | Nogle gange (5–29 %) | I 1 tilstand |
| SCN3Asodium voltage-gated channel alpha subunit 3 | Nogle gange (5–29 %) | I 1 tilstand |
| SLC1A2solute carrier family 1 member 2 | Nogle gange (5–29 %) | I 1 tilstand |
| SLC38A3solute carrier family 38 member 3 | Nogle gange (5–29 %) | I 1 tilstand |
| SNCAsynuclein alpha | Nogle gange (5–29 %) | I 2 tilstande |
| SYNGAP1synaptic Ras GTPase activating protein 1 | Nogle gange (5–29 %) | I 1 tilstand |
| SZT2SZT2 subunit of KICSTOR complex | Nogle gange (5–29 %) | I 1 tilstand |
| TRAK1trafficking kinesin protein 1 | Nogle gange (5–29 %) | I 1 tilstand |
| TTPAalpha tocopherol transfer protein | Nogle gange (5–29 %) | I 1 tilstand |
| UBA5ubiquitin like modifier activating enzyme 5 | Nogle gange (5–29 %) | I 1 tilstand |
| UBAP1ubiquitin associated protein 1 | Nogle gange (5–29 %) | I 1 tilstand |
| UFSP2UFM1 specific peptidase 2 | Nogle gange (5–29 %) | I 1 tilstand |
| VPS13Avacuolar protein sorting 13 homolog A | Nogle gange (5–29 %) | I 1 tilstand |
| VPS35VPS35 retromer complex component | Nogle gange (5–29 %) | I 1 tilstand |
| YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma | Nogle gange (5–29 %) | I 1 tilstand |
| KCNQ2potassium voltage-gated channel subfamily Q member 2 | Sjældent (1–4%) | I 1 tilstand |
| SCN2Asodium voltage-gated channel alpha subunit 2 | Sjældent (1–4%) | I 1 tilstand |
| TLR3toll like receptor 3 | Sjældent (1–4%) | I 1 tilstand |
| AP5Z1adaptor related protein complex 5 subunit zeta 1 | Ikke registreret | I 1 tilstand |
| ARSAarylsulfatase A | Ikke registreret | I 1 tilstand |
| BSCL2BSCL2 lipid droplet biogenesis associated, seipin | Ikke registreret | I 1 tilstand |
| C19orf12chromosome 19 open reading frame 12 | Ikke registreret | I 1 tilstand |
| CLN8CLN8 transmembrane ER and ERGIC protein | Ikke registreret | I 1 tilstand |
| COASYCoenzyme A synthase | Ikke registreret | I 1 tilstand |
| CSF1Rcolony stimulating factor 1 receptor | Ikke registreret | I 2 tilstande |
| CTC1CST telomere replication complex component 1 | Ikke registreret | I 1 tilstand |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Ikke registreret | I 1 tilstand |
| GBA2glucosylceramidase beta 2 | Ikke registreret | I 1 tilstand |
| GNASGNAS complex locus | Ikke registreret | I 1 tilstand |
| MFSD8major facilitator superfamily domain containing 8 | Ikke registreret | I 1 tilstand |
| NAA60N-alpha-acetyltransferase 60, NatF catalytic subunit | Ikke registreret | I 1 tilstand |
| PDE10Aphosphodiesterase 10A | Ikke registreret | I 1 tilstand |
| PDE11Aphosphodiesterase 11A | Ikke registreret | I 1 tilstand |
| PDGFBplatelet derived growth factor subunit B | Ikke registreret | I 1 tilstand |
| PDGFRBplatelet derived growth factor receptor beta | Ikke registreret | I 1 tilstand |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Ikke registreret | I 1 tilstand |
| PRKCGprotein kinase C gamma | Ikke registreret | I 1 tilstand |
| SGPL1sphingosine-1-phosphate lyase 1 | Ikke registreret | I 1 tilstand |
| SLC20A2solute carrier family 20 member 2 | Ikke registreret | I 1 tilstand |
| TBK1TANK binding kinase 1 | Ikke registreret | I 1 tilstand |
| UBTFupstream binding transcription factor | Ikke registreret | I 1 tilstand |
| XPR1xenotropic and polytropic retrovirus receptor 1 | Ikke registreret | I 1 tilstand |
Hvor hyppigt det ses hos personer med en af genets tilstande, den hyppigste værdi på tværs af dem, sådan som Human Phenotype Ontology registrerer det. Disse sider beskriver egenskaber og den forskning, der ligger bag dem. De er ikke en diagnose, og hvis du har spørgsmål om symptomer, bør du spørge en læge eller genetisk rådgiver.
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Hvor oplysningerne kommer fra
- Human Phenotype Ontology, udgivelse 2026-09-01: egenskaben, dens navne, definition og de gener, der er knyttet til den. Læs mere på hpo.jax.org.
- Dataudgivelse 2026.10.16-c6eea6bf.
Én test. Svar for hele livet.
Fra 449 $Gratis forsendelse · Resultater på 6–8 uger