Træk
Dementia
A loss of global cognitive ability of sufficient amount to interfere with normal social or occupational function. Dementia represents a loss of previously present cognitive abilities, generally in adults, and can affect memory, thinking, language, judgment, and behavior.
Resumé
- Også kaldet
- Dementia, progressive, Progressive dementia
- Kropssystem
- Abnormality of the nervous system
ReferencegenomGRCh38hg38
Positioner på gen- og variantsider følger dette valg i denne browser.
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Bestil min Genome Test195 gener knyttet til Dementia
Ændringer i disse gener forårsager sjældne tilstande, hvor Dementia ses. De fleste med dette træk har ingen af disse tilstande, og et gen på denne liste siger intet om nogens eget genom.
| Gen | Hvor ofte det ses | Tilstande |
|---|---|---|
| AARS1alanyl-tRNA synthetase 1 | Altid | I 1 tilstand |
| ABCB7ATP binding cassette subfamily B member 7 | Altid | I 1 tilstand |
| ATP13A2ATPase cation transporting 13A2 | Altid | I 4 tilstande |
| CERS1ceramide synthase 1 | Altid | I 1 tilstand |
| CTSFcathepsin F | Altid | I 1 tilstand |
| CYLDCYLD lysine 63 deubiquitinase | Altid | I 1 tilstand |
| DNAJC5DnaJ heat shock protein family (Hsp40) member C5 | Altid | I 1 tilstand |
| GBA2glucosylceramidase beta 2 | Altid | I 2 tilstande |
| GPRC5BG protein-coupled receptor class C group 5 member B | Altid | I 1 tilstand |
| PRKAR1Bprotein kinase cAMP-dependent type I regulatory subunit beta | Altid | I 1 tilstand |
| PRNPprion protein (Kanno blood group) | Altid | I 9 tilstande |
| SPG21SPG21 abhydrolase domain containing, maspardin | Altid | I 2 tilstande |
| TBPTATA-box binding protein | Altid | I 2 tilstande |
| TREM2triggering receptor expressed on myeloid cells 2 | Altid | I 5 tilstande |
| TYROBPtransmembrane immune signaling adaptor TYROBP | Altid | I 1 tilstand |
| VPS13Cvacuolar protein sorting 13 homolog C | Altid | I 2 tilstande |
| WDR45WD repeat domain 45 | Altid | I 2 tilstande |
| APPamyloid beta precursor protein | Meget ofte (80–99 %) | I 7 tilstande |
| ATP6V0A2ATPase H+ transporting V0 subunit a2 | Meget ofte (80–99 %) | I 1 tilstand |
| ATP6V1AATPase H+ transporting V1 subunit A | Meget ofte (80–99 %) | I 1 tilstand |
| ATP6V1E1ATPase H+ transporting V1 subunit E1 | Meget ofte (80–99 %) | I 1 tilstand |
| FMR1fragile X messenger ribonucleoprotein 1 | Meget ofte (80–99 %) | I 2 tilstande |
| HTRA1HtrA serine peptidase 1 | Meget ofte (80–99 %) | I 3 tilstande |
| MT-CO1mitochondrially encoded cytochrome c oxidase I | Meget ofte (80–99 %) | I 2 tilstande |
| MT-CO2mitochondrially encoded cytochrome c oxidase II | Meget ofte (80–99 %) | I 2 tilstande |
| MT-CO3mitochondrially encoded cytochrome c oxidase III | Meget ofte (80–99 %) | I 2 tilstande |
| MT-ND1mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | Meget ofte (80–99 %) | I 2 tilstande |
| MT-ND4mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | Meget ofte (80–99 %) | I 1 tilstand |
| MT-ND5mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | Meget ofte (80–99 %) | I 2 tilstande |
| MT-ND6mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | Meget ofte (80–99 %) | I 2 tilstande |
| MT-TFmitochondrially encoded tRNA-Phe (UUU/C) | Meget ofte (80–99 %) | I 2 tilstande |
| MT-THmitochondrially encoded tRNA-His (CAU/C) | Meget ofte (80–99 %) | I 2 tilstande |
| MT-TL1mitochondrially encoded tRNA-Leu (UUA/G) 1 | Meget ofte (80–99 %) | I 3 tilstande |
| MT-TQmitochondrially encoded tRNA-Gln (CAA/G) | Meget ofte (80–99 %) | I 2 tilstande |
| MT-TS1mitochondrially encoded tRNA-Ser (UCN) 1 | Meget ofte (80–99 %) | I 2 tilstande |
| MT-TS2mitochondrially encoded tRNA-Ser (AGU/C) 2 | Meget ofte (80–99 %) | I 2 tilstande |
| MT-TWmitochondrially encoded tRNA-Trp (UGA/G) | Meget ofte (80–99 %) | I 2 tilstande |
| PSEN1presenilin 1 | Meget ofte (80–99 %) | I 4 tilstande |
| PSEN2presenilin 2 | Meget ofte (80–99 %) | I 3 tilstande |
| ROGDIrogdi atypical leucine zipper | Meget ofte (80–99 %) | I 2 tilstande |
Vis 155 gener mere
| Gen | Hvor ofte det ses | Tilstande |
|---|---|---|
| SLC13A5solute carrier family 13 member 5 | Meget ofte (80–99 %) | I 1 tilstand |
| SORL1sortilin related receptor 1 | Meget ofte (80–99 %) | I 1 tilstand |
| TOMM40translocase of outer mitochondrial membrane 40 | Meget ofte (80–99 %) | I 1 tilstand |
| WFS1wolframin ER transmembrane glycoprotein | Meget ofte (80–99 %) | I 2 tilstande |
| ADA2adenosine deaminase 2 | Ofte (30–79 %) | I 1 tilstand |
| APOEapolipoprotein E | Ofte (30–79 %) | I 3 tilstande |
| ARSAarylsulfatase A | Ofte (30–79 %) | I 1 tilstand |
| ATN1atrophin 1 | Ofte (30–79 %) | I 2 tilstande |
| ATXN2ataxin 2 | Ofte (30–79 %) | I 3 tilstande |
| CBLIFcobalamin binding intrinsic factor | Ofte (30–79 %) | I 1 tilstand |
| CHMP2Bcharged multivesicular body protein 2B | Ofte (30–79 %) | I 1 tilstand |
| CLN6CLN6 transmembrane ER protein | Ofte (30–79 %) | I 1 tilstand |
| CMPK2cytidine/uridine monophosphate kinase 2 | Ofte (30–79 %) | I 1 tilstand |
| CSTBcystatin B | Ofte (30–79 %) | I 2 tilstande |
| DNMT1DNA methyltransferase 1 | Ofte (30–79 %) | I 2 tilstande |
| EPG5ectopic P-granules 5 autophagy tethering factor | Ofte (30–79 %) | I 1 tilstand |
| EPM2AEPM2A glucan phosphatase, laforin | Ofte (30–79 %) | I 2 tilstande |
| GBA1glucosylceramidase beta 1 | Ofte (30–79 %) | I 5 tilstande |
| GRNgranulin precursor | Ofte (30–79 %) | I 1 tilstand |
| HTThuntingtin | Ofte (30–79 %) | I 2 tilstande |
| JAM2junctional adhesion molecule 2 | Ofte (30–79 %) | I 1 tilstand |
| MAPTmicrotubule associated protein tau | Ofte (30–79 %) | I 5 tilstande |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Ofte (30–79 %) | I 1 tilstand |
| MT-ATP6mitochondrially encoded ATP synthase membrane subunit 6 | Ofte (30–79 %) | I 2 tilstande |
| MYORGmyogenesis regulating glycosidase | Ofte (30–79 %) | I 1 tilstand |
| NAA60N-alpha-acetyltransferase 60, NatF catalytic subunit | Ofte (30–79 %) | I 1 tilstand |
| NDUFA1NADH:ubiquinone oxidoreductase subunit A1 | Ofte (30–79 %) | I 1 tilstand |
| NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1 | Ofte (30–79 %) | I 2 tilstande |
| NOTCH2NLCnotch 2 N-terminal like C | Ofte (30–79 %) | I 2 tilstande |
| NOTCH3notch receptor 3 | Ofte (30–79 %) | I 2 tilstande |
| PANK2pantothenate kinase 2 | Ofte (30–79 %) | I 1 tilstand |
| PDGFBplatelet derived growth factor subunit B | Ofte (30–79 %) | I 2 tilstande |
| PDGFRBplatelet derived growth factor receptor beta | Ofte (30–79 %) | I 2 tilstande |
| PSAPprosaposin | Ofte (30–79 %) | I 1 tilstand |
| RNF216ring finger protein 216 | Ofte (30–79 %) | I 2 tilstande |
| RRP12ribosomal RNA processing 12 homolog | Ofte (30–79 %) | I 1 tilstand |
| SLC20A2solute carrier family 20 member 2 | Ofte (30–79 %) | I 1 tilstand |
| TMEM106Btransmembrane protein 106B | Ofte (30–79 %) | I 1 tilstand |
| TREX1three prime repair exonuclease 1 | Ofte (30–79 %) | I 1 tilstand |
| TRPM7transient receptor potential cation channel subfamily M member 7 | Ofte (30–79 %) | I 1 tilstand |
| VCPvalosin containing protein | Ofte (30–79 %) | I 2 tilstande |
| XPR1xenotropic and polytropic retrovirus receptor 1 | Ofte (30–79 %) | I 2 tilstande |
| AARS2alanyl-tRNA synthetase 2, mitochondrial | Nogle gange (5–29 %) | I 1 tilstand |
| ALDH18A1aldehyde dehydrogenase 18 family member A1 | Nogle gange (5–29 %) | I 2 tilstande |
| AUHAU RNA binding methylglutaconyl-CoA hydratase | Nogle gange (5–29 %) | I 1 tilstand |
| CISD2CDGSH iron sulfur domain 2 | Nogle gange (5–29 %) | I 1 tilstand |
| CLN8CLN8 transmembrane ER and ERGIC protein | Nogle gange (5–29 %) | I 1 tilstand |
| COL4A1collagen type IV alpha 1 chain | Nogle gange (5–29 %) | I 1 tilstand |
| DCTN1dynactin subunit 1 | Nogle gange (5–29 %) | I 1 tilstand |
| DGUOKdeoxyguanosine kinase | Nogle gange (5–29 %) | I 2 tilstande |
| DLATdihydrolipoamide S-acetyltransferase | Nogle gange (5–29 %) | I 1 tilstand |
| DNAJC6DnaJ heat shock protein family (Hsp40) member C6 | Nogle gange (5–29 %) | I 1 tilstand |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Nogle gange (5–29 %) | I 1 tilstand |
| FBXO7F-box protein 7 | Nogle gange (5–29 %) | I 1 tilstand |
| GALCgalactosylceramidase | Nogle gange (5–29 %) | I 1 tilstand |
| GBE11,4-alpha-glucan branching enzyme 1 | Nogle gange (5–29 %) | I 1 tilstand |
| GCDHglutaryl-CoA dehydrogenase | Nogle gange (5–29 %) | I 1 tilstand |
| HTRA2HtrA serine peptidase 2 | Nogle gange (5–29 %) | I 1 tilstand |
| JPH3junctophilin 3 | Nogle gange (5–29 %) | I 2 tilstande |
| KCTD7potassium channel tetramerization domain containing 7 | Nogle gange (5–29 %) | I 1 tilstand |
| LRRK2leucine rich repeat kinase 2 | Nogle gange (5–29 %) | I 3 tilstande |
| LYSTlysosomal trafficking regulator | Nogle gange (5–29 %) | I 1 tilstand |
| MATR3matrin 3 | Nogle gange (5–29 %) | I 2 tilstande |
| MT-ATP8mitochondrially encoded ATP synthase membrane subunit 8 | Nogle gange (5–29 %) | I 1 tilstand |
| PARK7Parkinsonism associated deglycase | Nogle gange (5–29 %) | I 1 tilstand |
| PINK1PTEN induced kinase 1 | Nogle gange (5–29 %) | I 2 tilstande |
| PNPLA6patatin like domain 6, lysophospholipase | Nogle gange (5–29 %) | I 1 tilstand |
| PODXLpodocalyxin like | Nogle gange (5–29 %) | I 1 tilstand |
| POLGDNA polymerase gamma, catalytic subunit | Nogle gange (5–29 %) | I 3 tilstande |
| PPP2R2Bprotein phosphatase 2 regulatory subunit Bbeta | Nogle gange (5–29 %) | I 2 tilstande |
| PRICKLE1prickle planar cell polarity protein 1 | Nogle gange (5–29 %) | I 1 tilstand |
| PRKNparkin RBR E3 ubiquitin protein ligase | Nogle gange (5–29 %) | I 1 tilstand |
| RAB39BRAB39B, member RAS oncogene family | Nogle gange (5–29 %) | I 1 tilstand |
| RRM2Bribonucleotide reductase regulatory TP53 inducible subunit M2B | Nogle gange (5–29 %) | I 2 tilstande |
| SCARB2scavenger receptor class B member 2 | Nogle gange (5–29 %) | I 1 tilstand |
| SMPD1sphingomyelin phosphodiesterase 1 | Nogle gange (5–29 %) | I 1 tilstand |
| SNCAsynuclein alpha | Nogle gange (5–29 %) | I 6 tilstande |
| SPG11SPG11 vesicle trafficking associated, spatacsin | Nogle gange (5–29 %) | I 1 tilstand |
| SYNJ1synaptojanin 1 | Nogle gange (5–29 %) | I 1 tilstand |
| TIMM8Atranslocase of inner mitochondrial membrane 8A | Nogle gange (5–29 %) | I 1 tilstand |
| TUBA4Atubulin alpha 4a | Nogle gange (5–29 %) | I 1 tilstand |
| TUBB4Atubulin beta 4A class IVa | Nogle gange (5–29 %) | I 1 tilstand |
| TWNKtwinkle mtDNA helicase | Nogle gange (5–29 %) | I 2 tilstande |
| UCHL1ubiquitin C-terminal hydrolase L1 | Nogle gange (5–29 %) | I 1 tilstand |
| VPS13Avacuolar protein sorting 13 homolog A | Nogle gange (5–29 %) | I 1 tilstand |
| ZFYVE26zinc finger FYVE-type containing 26 | Nogle gange (5–29 %) | I 1 tilstand |
| ATRXATRX chromatin remodeler | Sjældent (1–4%) | I 1 tilstand |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Sjældent (1–4%) | I 1 tilstand |
| CDH23cadherin related 23 | Sjældent (1–4%) | I 1 tilstand |
| DNAJC13DnaJ heat shock protein family (Hsp40) member C13 | Sjældent (1–4%) | I 1 tilstand |
| DNM1Ldynamin 1L | Sjældent (1–4%) | I 1 tilstand |
| EIF4G1eukaryotic translation initiation factor 4 gamma 1 | Sjældent (1–4%) | I 1 tilstand |
| GIGYF2GRB10 interacting GYF protein 2 | Sjældent (1–4%) | I 1 tilstand |
| LIG3DNA ligase 3 | Sjældent (1–4%) | I 1 tilstand |
| LMNB1lamin B1 | Sjældent (1–4%) | I 1 tilstand |
| MMACHCmetabolism of cobalamin associated C | Sjældent (1–4%) | I 2 tilstande |
| MT-TEmitochondrially encoded tRNA-Glu (GAA/G) | Sjældent (1–4%) | I 1 tilstand |
| NR3C1nuclear receptor subfamily 3 group C member 1 | Sjældent (1–4%) | I 1 tilstand |
| OPA1OPA1 mitochondrial dynamin like GTPase | Sjældent (1–4%) | I 1 tilstand |
| PPIBpeptidylprolyl isomerase B | Sjældent (1–4%) | I 1 tilstand |
| SDHAsuccinate dehydrogenase complex flavoprotein subunit A | Sjældent (1–4%) | I 1 tilstand |
| SDHAF1succinate dehydrogenase complex assembly factor 1 | Sjældent (1–4%) | I 1 tilstand |
| SDHBsuccinate dehydrogenase complex iron sulfur subunit B | Sjældent (1–4%) | I 1 tilstand |
| SDHDsuccinate dehydrogenase complex subunit D | Sjældent (1–4%) | I 1 tilstand |
| STARD7StAR related lipid transfer domain containing 7 | Sjældent (1–4%) | I 1 tilstand |
| TP53tumor protein p53 | Sjældent (1–4%) | I 1 tilstand |
| TYMPthymidine phosphorylase | Sjældent (1–4%) | I 1 tilstand |
| USP48ubiquitin specific peptidase 48 | Sjældent (1–4%) | I 1 tilstand |
| USP8ubiquitin specific peptidase 8 | Sjældent (1–4%) | I 1 tilstand |
| VPS35VPS35 retromer complex component | Sjældent (1–4%) | I 1 tilstand |
| ABCD1ATP binding cassette subfamily D member 1 | Ikke registreret | I 1 tilstand |
| ADH1Calcohol dehydrogenase 1C (class I), gamma polypeptide | Ikke registreret | I 1 tilstand |
| APTXaprataxin | Ikke registreret | I 1 tilstand |
| ASAH1N-acylsphingosine amidohydrolase 1 | Ikke registreret | I 1 tilstand |
| ATP7BATPase copper transporting beta | Ikke registreret | I 1 tilstand |
| ATXN10ataxin 10 | Ikke registreret | I 1 tilstand |
| ATXN3ataxin 3 | Ikke registreret | I 2 tilstande |
| ATXN8OSATXN8 opposite strand lncRNA | Ikke registreret | I 1 tilstand |
| C19orf12chromosome 19 open reading frame 12 | Ikke registreret | I 1 tilstand |
| C9orf72C9orf72-SMCR8 complex subunit | Ikke registreret | I 1 tilstand |
| CFAP43cilia and flagella associated protein 43 | Ikke registreret | I 1 tilstand |
| CLN3CLN3 lysosomal/endosomal transmembrane protein, battenin | Ikke registreret | I 1 tilstand |
| CPceruloplasmin | Ikke registreret | I 1 tilstand |
| CPT1Ccarnitine palmitoyltransferase 1C | Ikke registreret | I 1 tilstand |
| CST3cystatin C | Ikke registreret | I 1 tilstand |
| CUBNcubilin | Ikke registreret | I 1 tilstand |
| CYP27A1cytochrome P450 family 27 subfamily A member 1 | Ikke registreret | I 1 tilstand |
| ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Ikke registreret | I 1 tilstand |
| FTLferritin light chain | Ikke registreret | I 1 tilstand |
| GM2Aganglioside GM2 activator | Ikke registreret | I 1 tilstand |
| HEXAhexosaminidase subunit alpha | Ikke registreret | I 1 tilstand |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Ikke registreret | I 1 tilstand |
| IRF6interferon regulatory factor 6 | Ikke registreret | I 1 tilstand |
| ITM2Bintegral membrane protein 2B | Ikke registreret | I 2 tilstande |
| MMEmembrane metalloendopeptidase | Ikke registreret | I 1 tilstand |
| MPOmyeloperoxidase | Ikke registreret | I 1 tilstand |
| MT-CYBmitochondrially encoded cytochrome b | Ikke registreret | I 1 tilstand |
| MT-TCmitochondrially encoded tRNA-Cys (UGU/C) | Ikke registreret | I 1 tilstand |
| MT-TKmitochondrially encoded tRNA-Lys (AAA/G) | Ikke registreret | I 1 tilstand |
| MT-TL2mitochondrially encoded tRNA-Leu (CUN) 2 | Ikke registreret | I 1 tilstand |
| MT-TTmitochondrially encoded tRNA-Thr (ACN) | Ikke registreret | I 1 tilstand |
| MT-TVmitochondrially encoded tRNA-Val (GUN) | Ikke registreret | I 1 tilstand |
| NDPnorrin cystine knot growth factor NDP | Ikke registreret | I 1 tilstand |
| NPC1NPC intracellular cholesterol transporter 1 | Ikke registreret | I 1 tilstand |
| NPC2NPC intracellular cholesterol transporter 2 | Ikke registreret | I 1 tilstand |
| NR4A2nuclear receptor subfamily 4 group A member 2 | Ikke registreret | I 1 tilstand |
| PDE10Aphosphodiesterase 10A | Ikke registreret | I 1 tilstand |
| PLAUplasminogen activator, urokinase | Ikke registreret | I 1 tilstand |
| PRDM8PR/SET domain 8 | Ikke registreret | I 1 tilstand |
| PRDX1peroxiredoxin 1 | Ikke registreret | I 1 tilstand |
| SERPINI1serpin family I member 1 | Ikke registreret | I 1 tilstand |
| SNCAIPsynuclein alpha interacting protein | Ikke registreret | I 1 tilstand |
| SNCBsynuclein beta | Ikke registreret | I 1 tilstand |
| SPASTspastin | Ikke registreret | I 1 tilstand |
| TTRtransthyretin | Ikke registreret | I 1 tilstand |
Hvor hyppigt det ses hos personer med en af genets tilstande, den hyppigste værdi på tværs af dem, sådan som Human Phenotype Ontology registrerer det. Disse sider beskriver egenskaber og den forskning, der ligger bag dem. De er ikke en diagnose, og hvis du har spørgsmål om symptomer, bør du spørge en læge eller genetisk rådgiver.
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Hvor oplysningerne kommer fra
- Human Phenotype Ontology, udgivelse 2026-09-01: egenskaben, dens navne, definition og de gener, der er knyttet til den. Læs mere på hpo.jax.org.
- Dataudgivelse 2026.10.16-c6eea6bf.
Én test. Svar for hele livet.
Fra 449 $Gratis forsendelse · Resultater på 6–8 uger