Požymis
Delayed puberty
Passing the age when puberty normally occurs with no physical or hormonal signs of the onset of puberty.
Santrauka
- Taip pat vadinama
- Delayed pubertal development, Delayed pubertal growth, Pubertal delay
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Delayed puberty, and the rest of your genome, with one test.
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Įsigyti savo Genome Test199 genų susiję su Delayed puberty
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Delayed puberty. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| BMP15bone morphogenetic protein 15 | Visada | 2 ligose |
| BTKBruton tyrosine kinase | Visada | 1 ligoje |
| DCAF17DDB1 and CUL4 associated factor 17 | Visada | 2 ligose |
| ESR1estrogen receptor 1 | Visada | 1 ligoje |
| FAM111BFAM111 trypsin like peptidase B | Visada | 1 ligoje |
| GTF3C3general transcription factor IIIC subunit 3 | Visada | 1 ligoje |
| HROBhomologous recombination factor with OB-fold | Visada | 1 ligoje |
| LEPRleptin receptor | Visada | 1 ligoje |
| PRDM13PR/SET domain 13 | Visada | 1 ligoje |
| PSMC3IPPSMC3 interacting protein | Visada | 2 ligose |
| RBM28RNA binding motif protein 28 | Visada | 2 ligose |
| RNU2-2RNA, U2 small nuclear 2 | Visada | 1 ligoje |
| RNU6ATACRNA, U6atac small nuclear | Visada | 1 ligoje |
| SPIDRscaffold protein involved in DNA repair | Visada | 2 ligose |
| TAF13TATA-box binding protein associated factor 13 | Visada | 1 ligoje |
| TRA2Btransformer 2 beta homolog | Visada | 1 ligoje |
| ZSWIM7zinc finger SWIM-type containing 7 | Visada | 2 ligose |
| ANOS1anosmin 1 | Labai dažnai (80–99%) | 1 ligoje |
| ATMATM serine/threonine kinase | Labai dažnai (80–99%) | 2 ligose |
| BNC1basonuclin zinc finger protein 1 | Labai dažnai (80–99%) | 1 ligoje |
| CCDC141coiled-coil domain containing 141 | Labai dažnai (80–99%) | 1 ligoje |
| CHD7chromodomain helicase DNA binding protein 7 | Labai dažnai (80–99%) | 4 ligose |
| CYB5Acytochrome b5 type A | Labai dažnai (80–99%) | 1 ligoje |
| CYP11A1cytochrome P450 family 11 subfamily A member 1 | Labai dažnai (80–99%) | 2 ligose |
| CYP17A1cytochrome P450 family 17 subfamily A member 1 | Labai dažnai (80–99%) | 2 ligose |
| DCCDCC netrin 1 receptor | Labai dažnai (80–99%) | 1 ligoje |
| DUSP6dual specificity phosphatase 6 | Labai dažnai (80–99%) | 2 ligose |
| EMX2empty spiracles homeobox 2 | Labai dažnai (80–99%) | 2 ligose |
| FEZF1FEZ family zinc finger 1 | Labai dažnai (80–99%) | 1 ligoje |
| FGF17fibroblast growth factor 17 | Labai dažnai (80–99%) | 3 ligose |
| FGF8fibroblast growth factor 8 | Labai dažnai (80–99%) | 3 ligose |
| FGFR1fibroblast growth factor receptor 1 | Labai dažnai (80–99%) | 3 ligose |
| FIGLAfolliculogenesis specific bHLH transcription factor | Labai dažnai (80–99%) | 1 ligoje |
| FLRT3fibronectin leucine rich transmembrane protein 3 | Labai dažnai (80–99%) | 2 ligose |
| FSHBfollicle stimulating hormone subunit beta | Labai dažnai (80–99%) | 1 ligoje |
| FSHRfollicle stimulating hormone receptor | Labai dažnai (80–99%) | 1 ligoje |
| GBA1glucosylceramidase beta 1 | Labai dažnai (80–99%) | 2 ligose |
| HESX1HESX homeobox 1 | Labai dažnai (80–99%) | 3 ligose |
| HS6ST1heparan sulfate 6-O-sulfotransferase 1 | Labai dažnai (80–99%) | 2 ligose |
| IL17RDinterleukin 17 receptor D | Labai dažnai (80–99%) | 1 ligoje |
Rodyti dar 159 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| INSRinsulin receptor | Labai dažnai (80–99%) | 1 ligoje |
| LMNAlamin A/C | Labai dažnai (80–99%) | 1 ligoje |
| MRPS22mitochondrial ribosomal protein S22 | Labai dažnai (80–99%) | 2 ligose |
| MSH4mutS homolog 4 | Labai dažnai (80–99%) | 1 ligoje |
| NDNFneuron derived neurotrophic factor | Labai dažnai (80–99%) | 1 ligoje |
| NR5A1nuclear receptor subfamily 5 group A member 1 | Labai dažnai (80–99%) | 2 ligose |
| NUP107nucleoporin 107 | Labai dažnai (80–99%) | 1 ligoje |
| POLR3ARNA polymerase III subunit A | Labai dažnai (80–99%) | 2 ligose |
| POLR3BRNA polymerase III subunit B | Labai dažnai (80–99%) | 1 ligoje |
| POLR3HRNA polymerase III subunit H | Labai dažnai (80–99%) | 1 ligoje |
| PROK2prokineticin 2 | Labai dažnai (80–99%) | 2 ligose |
| PROKR2prokineticin receptor 2 | Labai dažnai (80–99%) | 3 ligose |
| RAB18RAB18, member RAS oncogene family | Labai dažnai (80–99%) | 1 ligoje |
| RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1 | Labai dažnai (80–99%) | 1 ligoje |
| RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2 | Labai dažnai (80–99%) | 1 ligoje |
| SCARB2scavenger receptor class B member 2 | Labai dažnai (80–99%) | 1 ligoje |
| SEMA3Asemaphorin 3A | Labai dažnai (80–99%) | 1 ligoje |
| SEMA3Esemaphorin 3E | Labai dažnai (80–99%) | 1 ligoje |
| SLC29A3solute carrier family 29 member 3 | Labai dažnai (80–99%) | 1 ligoje |
| SOX10SRY-box transcription factor 10 | Labai dažnai (80–99%) | 1 ligoje |
| SPRY4sprouty RTK signaling antagonist 4 | Labai dažnai (80–99%) | 2 ligose |
| TACR3tachykinin receptor 3 | Labai dažnai (80–99%) | 2 ligose |
| TBC1D20TBC1 domain family member 20 | Labai dažnai (80–99%) | 1 ligoje |
| WDR11WD repeat domain 11 | Labai dažnai (80–99%) | 3 ligose |
| ARandrogen receptor | Dažnai (30–79%) | 1 ligoje |
| BRCC3BRCA1/BRCA2-containing complex subunit 3 | Dažnai (30–79%) | 1 ligoje |
| CDONcell adhesion associated, oncogene regulated | Dažnai (30–79%) | 1 ligoje |
| CPEcarboxypeptidase E | Dažnai (30–79%) | 1 ligoje |
| DHX37DEAH-box helicase 37 | Dažnai (30–79%) | 1 ligoje |
| ENTPD1ectonucleoside triphosphate diphosphohydrolase 1 | Dažnai (30–79%) | 2 ligose |
| GALTgalactose-1-phosphate uridylyltransferase | Dažnai (30–79%) | 1 ligoje |
| GATA4GATA binding protein 4 | Dažnai (30–79%) | 1 ligoje |
| GHRgrowth hormone receptor | Dažnai (30–79%) | 2 ligose |
| GLAgalactosidase alpha | Dažnai (30–79%) | 2 ligose |
| GNRH1gonadotropin releasing hormone 1 | Dažnai (30–79%) | 2 ligose |
| GNRHRgonadotropin releasing hormone receptor | Dažnai (30–79%) | 1 ligoje |
| GPR161G protein-coupled receptor 161 | Dažnai (30–79%) | 1 ligoje |
| HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2 | Dažnai (30–79%) | 1 ligoje |
| IGFALSinsulin like growth factor binding protein acid labile subunit | Dažnai (30–79%) | 2 ligose |
| KISS1KiSS-1 metastasis suppressor | Dažnai (30–79%) | 1 ligoje |
| KISS1RKISS1 receptor | Dažnai (30–79%) | 1 ligoje |
| LHX4LIM homeobox 4 | Dažnai (30–79%) | 2 ligose |
| LPIN2lipin 2 | Dažnai (30–79%) | 1 ligoje |
| MAGEL2MAGE family member L2 | Dažnai (30–79%) | 4 ligose |
| MAP3K1mitogen-activated protein kinase kinase kinase 1 | Dažnai (30–79%) | 1 ligoje |
| MKRN3makorin ring finger protein 3 | Dažnai (30–79%) | 1 ligoje |
| NDNnecdin, MAGE family member | Dažnai (30–79%) | 3 ligose |
| NHLH2nescient helix-loop-helix 2 | Dažnai (30–79%) | 1 ligoje |
| NONOnon-POU domain containing octamer binding | Dažnai (30–79%) | 2 ligose |
| NPAP1nuclear pore associated protein 1 | Dažnai (30–79%) | 1 ligoje |
| NR0B1nuclear receptor subfamily 0 group B member 1 | Dažnai (30–79%) | 3 ligose |
| NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor | Dažnai (30–79%) | 1 ligoje |
| OCA2OCA2 melanosomal transmembrane protein | Dažnai (30–79%) | 3 ligose |
| POLR3GLRNA polymerase III subunit GL | Dažnai (30–79%) | 1 ligoje |
| PPP1R15Bprotein phosphatase 1 regulatory subunit 15B | Dažnai (30–79%) | 2 ligose |
| PUS1pseudouridine synthase 1 | Dažnai (30–79%) | 2 ligose |
| PWAR1Prader Willi/Angelman region RNA 1 | Dažnai (30–79%) | 1 ligoje |
| PWRN1Prader-Willi region non-protein coding RNA 1 | Dažnai (30–79%) | 1 ligoje |
| PYGLglycogen phosphorylase L | Dažnai (30–79%) | 1 ligoje |
| ROBO1roundabout guidance receptor 1 | Dažnai (30–79%) | 1 ligoje |
| SMPD1sphingomyelin phosphodiesterase 1 | Dažnai (30–79%) | 1 ligoje |
| SNORD115-1small nucleolar RNA, C/D box 115-1 | Dažnai (30–79%) | 1 ligoje |
| SNORD116-1small nucleolar RNA, C/D box 116-1 | Dažnai (30–79%) | 1 ligoje |
| SNRPNsmall nuclear ribonucleoprotein polypeptide N | Dažnai (30–79%) | 3 ligose |
| SOX11SRY-box transcription factor 11 | Dažnai (30–79%) | 1 ligoje |
| SOX9SRY-box transcription factor 9 | Dažnai (30–79%) | 1 ligoje |
| SRYsex determining region Y | Dažnai (30–79%) | 2 ligose |
| STAT1signal transducer and activator of transcription 1 | Dažnai (30–79%) | 2 ligose |
| STAT5Bsignal transducer and activator of transcription 5B | Dažnai (30–79%) | 2 ligose |
| TAC3tachykinin precursor 3 | Dažnai (30–79%) | 1 ligoje |
| TBX3T-box transcription factor 3 | Dažnai (30–79%) | 2 ligose |
| TRMT10AtRNA methyltransferase 10A | Dažnai (30–79%) | 2 ligose |
| VAMP7vesicle associated membrane protein 7 | Dažnai (30–79%) | 1 ligoje |
| VPS13Bvacuolar protein sorting 13 homolog B | Dažnai (30–79%) | 2 ligose |
| WFS1wolframin ER transmembrane glycoprotein | Dažnai (30–79%) | 2 ligose |
| WT1WT1 transcription factor | Dažnai (30–79%) | 1 ligoje |
| WWOXWW domain containing oxidoreductase | Dažnai (30–79%) | 1 ligoje |
| YARS2tyrosyl-tRNA synthetase 2 | Dažnai (30–79%) | 1 ligoje |
| ZBTB20zinc finger and BTB domain containing 20 | Dažnai (30–79%) | 1 ligoje |
| ZFPM2zinc finger protein, FOG family member 2 | Dažnai (30–79%) | 1 ligoje |
| AIPAHR interacting HSP90 co-chaperone | Kartais (5–29%) | 1 ligoje |
| ALX4ALX homeobox 4 | Kartais (5–29%) | 1 ligoje |
| ATAD3AATPase family AAA domain containing 3A | Kartais (5–29%) | 1 ligoje |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Kartais (5–29%) | 1 ligoje |
| BRD4bromodomain containing 4 | Kartais (5–29%) | 1 ligoje |
| CARS1cysteinyl-tRNA synthetase 1 | Kartais (5–29%) | 1 ligoje |
| CDH23cadherin related 23 | Kartais (5–29%) | 2 ligose |
| CISD2CDGSH iron sulfur domain 2 | Kartais (5–29%) | 1 ligoje |
| CLCNKBchloride voltage-gated channel Kb | Kartais (5–29%) | 1 ligoje |
| COL7A1collagen type VII alpha 1 chain | Kartais (5–29%) | 2 ligose |
| CTNNB1catenin beta 1 | Kartais (5–29%) | 1 ligoje |
| DACT1dishevelled binding antagonist of beta catenin 1 | Kartais (5–29%) | 1 ligoje |
| DIAPH1diaphanous related formin 1 | Kartais (5–29%) | 1 ligoje |
| EIF5Aeukaryotic translation initiation factor 5A | Kartais (5–29%) | 1 ligoje |
| EXT2exostosin glycosyltransferase 2 | Kartais (5–29%) | 1 ligoje |
| FOXA2forkhead box A2 | Kartais (5–29%) | 1 ligoje |
| GHSRgrowth hormone secretagogue receptor | Kartais (5–29%) | 1 ligoje |
| GLI2GLI family zinc finger 2 | Kartais (5–29%) | 1 ligoje |
| HBBhemoglobin subunit beta | Kartais (5–29%) | 2 ligose |
| HDAC8histone deacetylase 8 | Kartais (5–29%) | 1 ligoje |
| MAP3K7mitogen-activated protein kinase kinase kinase 7 | Kartais (5–29%) | 1 ligoje |
| MAU2MAU2 sister chromatid cohesion factor | Kartais (5–29%) | 1 ligoje |
| MEN1menin 1 | Kartais (5–29%) | 1 ligoje |
| MMP1matrix metallopeptidase 1 | Kartais (5–29%) | 1 ligoje |
| MT-ATP8mitochondrially encoded ATP synthase membrane subunit 8 | Kartais (5–29%) | 1 ligoje |
| MT-TL1mitochondrially encoded tRNA-Leu (UUA/G) 1 | Kartais (5–29%) | 1 ligoje |
| NDPnorrin cystine knot growth factor NDP | Kartais (5–29%) | 1 ligoje |
| NF1neurofibromin 1 | Kartais (5–29%) | 1 ligoje |
| NIPBLNIPBL cohesin loading factor | Kartais (5–29%) | 1 ligoje |
| NLRP3NLR family pyrin domain containing 3 | Kartais (5–29%) | 1 ligoje |
| NOTCH2notch receptor 2 | Kartais (5–29%) | 1 ligoje |
| OCRLOCRL inositol polyphosphate-5-phosphatase | Kartais (5–29%) | 1 ligoje |
| OTX2orthodenticle homeobox 2 | Kartais (5–29%) | 1 ligoje |
| PCSK1proprotein convertase subtilisin/kexin type 1 | Kartais (5–29%) | 1 ligoje |
| PGM1phosphoglucomutase 1 | Kartais (5–29%) | 1 ligoje |
| PHF21APHD finger protein 21A | Kartais (5–29%) | 1 ligoje |
| PHKA2phosphorylase kinase regulatory subunit alpha 2 | Kartais (5–29%) | 1 ligoje |
| PHKG2phosphorylase kinase catalytic subunit gamma 2 | Kartais (5–29%) | 1 ligoje |
| POMCproopiomelanocortin | Kartais (5–29%) | 1 ligoje |
| PORcytochrome p450 oxidoreductase | Kartais (5–29%) | 1 ligoje |
| POU1F1POU class 1 homeobox 1 | Kartais (5–29%) | 1 ligoje |
| PROP1PROP paired-like homeobox 1 | Kartais (5–29%) | 2 ligose |
| PTRH2peptidyl-tRNA hydrolase 2 | Kartais (5–29%) | 2 ligose |
| RAD21RAD21 cohesin complex component | Kartais (5–29%) | 1 ligoje |
| RAI1retinoic acid induced 1 | Kartais (5–29%) | 1 ligoje |
| RPL10ribosomal protein L10 | Kartais (5–29%) | 1 ligoje |
| RRM2Bribonucleotide reductase regulatory TP53 inducible subunit M2B | Kartais (5–29%) | 1 ligoje |
| SALL1spalt like transcription factor 1 | Kartais (5–29%) | 1 ligoje |
| SLC12A3solute carrier family 12 member 3 | Kartais (5–29%) | 2 ligose |
| SLC37A4solute carrier family 37 member 4 | Kartais (5–29%) | 3 ligose |
| SMC1Astructural maintenance of chromosomes 1A | Kartais (5–29%) | 1 ligoje |
| SMC3structural maintenance of chromosomes 3 | Kartais (5–29%) | 1 ligoje |
| SOX3SRY-box transcription factor 3 | Kartais (5–29%) | 1 ligoje |
| STAT3signal transducer and activator of transcription 3 | Kartais (5–29%) | 1 ligoje |
| TGFB1transforming growth factor beta 1 | Kartais (5–29%) | 2 ligose |
| TRIP4thyroid hormone receptor interactor 4 | Kartais (5–29%) | 1 ligoje |
| USP9Xubiquitin specific peptidase 9 X-linked | Kartais (5–29%) | 1 ligoje |
| ZFXzinc finger protein X-linked | Kartais (5–29%) | 1 ligoje |
| ZMPSTE24zinc metallopeptidase STE24 | Kartais (5–29%) | 1 ligoje |
| SPTBN1spectrin beta, non-erythrocytic 1 | Retai (1–4 %) | 1 ligoje |
| ALDOAaldolase, fructose-bisphosphate A | Neužfiksuota | 1 ligoje |
| CENPTcentromere protein T | Neužfiksuota | 1 ligoje |
| CTNScystinosin, lysosomal cystine transporter | Neužfiksuota | 1 ligoje |
| CUL4Bcullin 4B | Neužfiksuota | 1 ligoje |
| EIF2S3eukaryotic translation initiation factor 2 subunit gamma | Neužfiksuota | 1 ligoje |
| FGD1FYVE, RhoGEF and PH domain containing 1 | Neužfiksuota | 1 ligoje |
| G6PC1glucose-6-phosphatase catalytic subunit 1 | Neužfiksuota | 1 ligoje |
| GMNNgeminin DNA replication inhibitor | Neužfiksuota | 1 ligoje |
| HLA-DQA1major histocompatibility complex, class II, DQ alpha 1 | Neužfiksuota | 1 ligoje |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Neužfiksuota | 1 ligoje |
| LGR4leucine rich repeat containing G protein-coupled receptor 4 | Neužfiksuota | 1 ligoje |
| LHBluteinizing hormone subunit beta | Neužfiksuota | 1 ligoje |
| MSMO1methylsterol monooxygenase 1 | Neužfiksuota | 1 ligoje |
| PHF6PHD finger protein 6 | Neužfiksuota | 1 ligoje |
| PNPLA6patatin like domain 6, lysophospholipase | Neužfiksuota | 1 ligoje |
| POF1BPOF1B actin binding protein | Neužfiksuota | 1 ligoje |
| PTPN11protein tyrosine phosphatase non-receptor type 11 | Neužfiksuota | 1 ligoje |
| TCF12transcription factor 12 | Neužfiksuota | 1 ligoje |
| TGFB2transforming growth factor beta 2 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
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- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
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