Tunnus
Decreased immune function
Kliiniline nimetus: Immunodeficiency
Failure of the immune system to protect the body adequately from infection, due to the absence or insufficiency of some component process or substance.
Kokkuvõte
- Teised nimetused
- Immune deficiency
- Kehasüsteem
- Abnormality of the immune system
VõrdlusgenoomGRCh38hg38
Geeni- ja variandilehtede positsioonid järgivad seda valikut selles brauseris.
Read the genes linked to Decreased immune function, and the rest of your genome, with one test.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast
Telli oma Genome Test173 geeni on seotud tunnusega Decreased immune function
Nende geenide muutused põhjustavad haruldasi haigusi, mille puhul esineb Decreased immune function. Enamikul selle tunnusega inimestest ei ole ühtegi neist haigustest. Selles loendis olev geen ei ütle midagi kellegi enda genoomi kohta.
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| AK2adenylate kinase 2 | Alati | Esineb 1 haiguses |
| AP3D1adaptor related protein complex 3 subunit delta 1 | Alati | Esineb 1 haiguses |
| ARPC5actin related protein 2/3 complex subunit 5 | Alati | Esineb 1 haiguses |
| CARD11caspase recruitment domain family member 11 | Alati | Esineb 1 haiguses |
| CD3ECD3 epsilon subunit of T-cell receptor complex | Alati | Esineb 1 haiguses |
| CORO1Acoronin 1A | Alati | Esineb 1 haiguses |
| DCLRE1BDNA cross-link repair 1B | Alati | Esineb 1 haiguses |
| DCLRE1CDNA cross-link repair 1C | Alati | Esineb 1 haiguses |
| DPP9dipeptidyl peptidase 9 | Alati | Esineb 1 haiguses |
| GATA2GATA binding protein 2 | Alati | Esineb 1 haiguses |
| GUK1guanylate kinase 1 | Alati | Esineb 1 haiguses |
| HYOU1hypoxia up-regulated 1 | Alati | Esineb 1 haiguses |
| IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gamma | Alati | Esineb 2 haiguses |
| IKZF2IKAROS family zinc finger 2 | Alati | Esineb 1 haiguses |
| ITPR3inositol 1,4,5-trisphosphate receptor type 3 | Alati | Esineb 1 haiguses |
| LCKLCK proto-oncogene, Src family tyrosine kinase | Alati | Esineb 1 haiguses |
| LCP2lymphocyte cytosolic protein 2 | Alati | Esineb 1 haiguses |
| MALT1MALT1 paracaspase | Alati | Esineb 1 haiguses |
| MAN2B2mannosidase alpha class 2B member 2 | Alati | Esineb 1 haiguses |
| MCM10minichromosome maintenance 10 replication initiation factor | Alati | Esineb 1 haiguses |
| NHEJ1non-homologous end joining factor 1 | Alati | Esineb 2 haiguses |
| PTCRApre T cell antigen receptor alpha | Alati | Esineb 1 haiguses |
| RAG1recombination activating 1 | Alati | Esineb 2 haiguses |
| RAG2recombination activating 2 | Alati | Esineb 1 haiguses |
| RNF31ring finger protein 31 | Alati | Esineb 1 haiguses |
| SIK3SIK family kinase 3 | Alati | Esineb 1 haiguses |
| SLC19A1solute carrier family 19 member 1 | Alati | Esineb 1 haiguses |
| STAT1signal transducer and activator of transcription 1 | Alati | Esineb 3 haiguses |
| STIM1stromal interaction molecule 1 | Alati | Esineb 1 haiguses |
| STK4serine/threonine kinase 4 | Alati | Esineb 1 haiguses |
| ACDACD shelterin complex subunit and telomerase recruitment factor | Väga sageli (80–99%) | Esineb 1 haiguses |
| ACTBactin beta | Väga sageli (80–99%) | Esineb 1 haiguses |
| AGLamylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase | Väga sageli (80–99%) | Esineb 1 haiguses |
| ANTXR2ANTXR cell adhesion molecule 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| ARVCFARVCF delta catenin family member | Väga sageli (80–99%) | Esineb 1 haiguses |
| ATMATM serine/threonine kinase | Väga sageli (80–99%) | Esineb 1 haiguses |
| BLNKB cell linker | Väga sageli (80–99%) | Esineb 1 haiguses |
| BTKBruton tyrosine kinase | Väga sageli (80–99%) | Esineb 1 haiguses |
| CD79ACD79a molecule | Väga sageli (80–99%) | Esineb 1 haiguses |
| CD79BCD79b molecule | Väga sageli (80–99%) | Esineb 1 haiguses |
Näita veel 133 geeni
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| CDCA7cell division cycle associated 7 | Väga sageli (80–99%) | Esineb 1 haiguses |
| COMTcatechol-O-methyltransferase | Väga sageli (80–99%) | Esineb 1 haiguses |
| DKC1dyskerin pseudouridine synthase 1 | Väga sageli (80–99%) | Esineb 2 haiguses |
| DNMT3BDNA methyltransferase 3 beta | Väga sageli (80–99%) | Esineb 2 haiguses |
| FOXN1forkhead box N1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| GP1BBglycoprotein Ib platelet subunit beta | Väga sageli (80–99%) | Esineb 1 haiguses |
| HELLShelicase, lymphoid specific | Väga sageli (80–99%) | Esineb 1 haiguses |
| HIRAhistone cell cycle regulator | Väga sageli (80–99%) | Esineb 1 haiguses |
| IGHMimmunoglobulin heavy constant mu | Väga sageli (80–99%) | Esineb 1 haiguses |
| IGLL1immunoglobulin lambda like polypeptide 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| IL12RB1interleukin 12 receptor subunit beta 1 | Väga sageli (80–99%) | Esineb 2 haiguses |
| IRAK4interleukin 1 receptor associated kinase 4 | Väga sageli (80–99%) | Esineb 2 haiguses |
| JMJD1Cjumonji domain containing 1C | Väga sageli (80–99%) | Esineb 1 haiguses |
| LAMTOR2late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | Väga sageli (80–99%) | Esineb 2 haiguses |
| LIG4DNA ligase 4 | Väga sageli (80–99%) | Esineb 1 haiguses |
| LRRC8Aleucine rich repeat containing 8 VRAC subunit A | Väga sageli (80–99%) | Esineb 1 haiguses |
| LYSTlysosomal trafficking regulator | Väga sageli (80–99%) | Esineb 2 haiguses |
| MAN2B1mannosidase alpha class 2B member 1 | Väga sageli (80–99%) | Esineb 2 haiguses |
| MYD88MYD88 innate immune signal transduction adaptor | Väga sageli (80–99%) | Esineb 1 haiguses |
| PARNpoly(A)-specific ribonuclease | Väga sageli (80–99%) | Esineb 1 haiguses |
| PIK3CDphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Väga sageli (80–99%) | Esineb 2 haiguses |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Väga sageli (80–99%) | Esineb 2 haiguses |
| POLEDNA polymerase epsilon, catalytic subunit | Väga sageli (80–99%) | Esineb 2 haiguses |
| RAB27ARAB27A, member RAS oncogene family | Väga sageli (80–99%) | Esineb 1 haiguses |
| RAC2Rac family small GTPase 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| RNF168ring finger protein 168 | Väga sageli (80–99%) | Esineb 2 haiguses |
| RREB1ras responsive element binding protein 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| RTEL1regulator of telomere elongation helicase 1 | Väga sageli (80–99%) | Esineb 2 haiguses |
| SEC24CSEC24 homolog C, COPII component | Väga sageli (80–99%) | Esineb 1 haiguses |
| SKIC2SKI2 subunit of superkiller complex | Väga sageli (80–99%) | Esineb 2 haiguses |
| SKIC3SKI3 subunit of superkiller complex | Väga sageli (80–99%) | Esineb 1 haiguses |
| SPI1Spi-1 proto-oncogene | Väga sageli (80–99%) | Esineb 1 haiguses |
| TBX1T-box transcription factor 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| TCF3transcription factor 3 | Väga sageli (80–99%) | Esineb 1 haiguses |
| TERCtelomerase RNA component | Väga sageli (80–99%) | Esineb 1 haiguses |
| TERTtelomerase reverse transcriptase | Väga sageli (80–99%) | Esineb 1 haiguses |
| TINF2TERF1 interacting nuclear factor 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| UFD1ubiquitin recognition factor in ER associated degradation 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| UHRF1ubiquitin like with PHD and ring finger domains 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| WASWASP actin nucleation promoting factor | Väga sageli (80–99%) | Esineb 1 haiguses |
| XIAPX-linked inhibitor of apoptosis | Väga sageli (80–99%) | Esineb 3 haiguses |
| ZBTB24zinc finger and BTB domain containing 24 | Väga sageli (80–99%) | Esineb 2 haiguses |
| ADA2adenosine deaminase 2 | Sageli (30–79%) | Esineb 1 haiguses |
| AFG2AAAA ATPase AFG2A | Sageli (30–79%) | Esineb 2 haiguses |
| ATRXATRX chromatin remodeler | Sageli (30–79%) | Esineb 2 haiguses |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Sageli (30–79%) | Esineb 1 haiguses |
| CCDC47coiled-coil domain containing 47 | Sageli (30–79%) | Esineb 1 haiguses |
| CD28CD28 molecule | Sageli (30–79%) | Esineb 1 haiguses |
| CDH23cadherin related 23 | Sageli (30–79%) | Esineb 1 haiguses |
| CHD1chromodomain helicase DNA binding protein 1 | Sageli (30–79%) | Esineb 2 haiguses |
| CPLX1complexin 1 | Sageli (30–79%) | Esineb 1 haiguses |
| CTBP1C-terminal binding protein 1 | Sageli (30–79%) | Esineb 1 haiguses |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Sageli (30–79%) | Esineb 2 haiguses |
| FGFRL1fibroblast growth factor receptor like 1 | Sageli (30–79%) | Esineb 1 haiguses |
| LETM1leucine zipper and EF-hand containing transmembrane protein 1 | Sageli (30–79%) | Esineb 1 haiguses |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Sageli (30–79%) | Esineb 1 haiguses |
| MMUTmethylmalonyl-CoA mutase | Sageli (30–79%) | Esineb 1 haiguses |
| NR3C1nuclear receptor subfamily 3 group C member 1 | Sageli (30–79%) | Esineb 1 haiguses |
| NSD2nuclear receptor binding SET domain protein 2 | Sageli (30–79%) | Esineb 1 haiguses |
| PI4KAphosphatidylinositol 4-kinase alpha | Sageli (30–79%) | Esineb 2 haiguses |
| RNU6ATACRNA, U6atac small nuclear | Sageli (30–79%) | Esineb 1 haiguses |
| TNFRSF1BTNF receptor superfamily member 1B | Sageli (30–79%) | Esineb 1 haiguses |
| TOP2BDNA topoisomerase II beta | Sageli (30–79%) | Esineb 1 haiguses |
| TP53tumor protein p53 | Sageli (30–79%) | Esineb 1 haiguses |
| TTC7Atetratricopeptide repeat domain 7A | Sageli (30–79%) | Esineb 1 haiguses |
| USP48ubiquitin specific peptidase 48 | Sageli (30–79%) | Esineb 1 haiguses |
| USP8ubiquitin specific peptidase 8 | Sageli (30–79%) | Esineb 1 haiguses |
| ALG1ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase | Mõnikord (5–29%) | Esineb 1 haiguses |
| BCRBCR activator of RhoGEF and GTPase | Mõnikord (5–29%) | Esineb 1 haiguses |
| CDC42cell division cycle 42 | Mõnikord (5–29%) | Esineb 2 haiguses |
| CRKLCRK like proto-oncogene, adaptor protein | Mõnikord (5–29%) | Esineb 1 haiguses |
| CUL4Bcullin 4B | Mõnikord (5–29%) | Esineb 1 haiguses |
| LMNB2lamin B2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MAPK1mitogen-activated protein kinase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MEIS2Meis homeobox 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| POGZpogo transposable element derived with ZNF domain | Mõnikord (5–29%) | Esineb 1 haiguses |
| SLC46A1solute carrier family 46 member 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TBK1TANK binding kinase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TICAM1TIR domain containing adaptor molecule 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TLR3toll like receptor 3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TRAF3TNF receptor associated factor 3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| UNC93B1unc-93B1 regulator of TLR signaling | Mõnikord (5–29%) | Esineb 1 haiguses |
| ZNF699zinc finger protein 699 | Mõnikord (5–29%) | Esineb 1 haiguses |
| AMNamnion associated transmembrane protein | Harva (1–4%) | Esineb 1 haiguses |
| CUBNcubilin | Harva (1–4%) | Esineb 1 haiguses |
| DNAJC21DnaJ heat shock protein family (Hsp40) member C21 | Harva (1–4%) | Esineb 1 haiguses |
| EFL1elongation factor like GTPase 1 | Harva (1–4%) | Esineb 1 haiguses |
| SBDSSBDS ribosome maturation factor | Harva (1–4%) | Esineb 1 haiguses |
| AICDAactivation induced cytidine deaminase | Pole registreeritud | Esineb 1 haiguses |
| BCL10BCL10 immune signaling adaptor | Pole registreeritud | Esineb 1 haiguses |
| CARD9caspase recruitment domain family member 9 | Pole registreeritud | Esineb 1 haiguses |
| CD247CD247 molecule | Pole registreeritud | Esineb 1 haiguses |
| CD3GCD3 gamma subunit of T-cell receptor complex | Pole registreeritud | Esineb 1 haiguses |
| CD40CD40 molecule | Pole registreeritud | Esineb 1 haiguses |
| CD40LGCD40 ligand | Pole registreeritud | Esineb 1 haiguses |
| CTPS1CTP synthase 1 | Pole registreeritud | Esineb 1 haiguses |
| CYBAcytochrome b-245 alpha chain | Pole registreeritud | Esineb 1 haiguses |
| CYBBcytochrome b-245 beta chain | Pole registreeritud | Esineb 1 haiguses |
| EPG5ectopic P-granules 5 autophagy tethering factor | Pole registreeritud | Esineb 1 haiguses |
| FCGR3AFc gamma receptor IIIa | Pole registreeritud | Esineb 1 haiguses |
| ICOSinducible T cell costimulator | Pole registreeritud | Esineb 1 haiguses |
| IFNGR1interferon gamma receptor 1 | Pole registreeritud | Esineb 1 haiguses |
| IFNGR2interferon gamma receptor 2 | Pole registreeritud | Esineb 1 haiguses |
| IKBKBinhibitor of nuclear factor kappa B kinase subunit beta | Pole registreeritud | Esineb 1 haiguses |
| IL12Binterleukin 12B | Pole registreeritud | Esineb 1 haiguses |
| IL21Rinterleukin 21 receptor | Pole registreeritud | Esineb 1 haiguses |
| IL2RAinterleukin 2 receptor subunit alpha | Pole registreeritud | Esineb 1 haiguses |
| IL2RBinterleukin 2 receptor subunit beta | Pole registreeritud | Esineb 1 haiguses |
| IRF7interferon regulatory factor 7 | Pole registreeritud | Esineb 1 haiguses |
| IRF8interferon regulatory factor 8 | Pole registreeritud | Esineb 2 haiguses |
| ISG15ISG15 ubiquitin like modifier | Pole registreeritud | Esineb 1 haiguses |
| IVNS1ABPinfluenza virus NS1A binding protein | Pole registreeritud | Esineb 1 haiguses |
| LATlinker for activation of T cells | Pole registreeritud | Esineb 1 haiguses |
| LRBALPS responsive beige-like anchor protein | Pole registreeritud | Esineb 1 haiguses |
| MAGT1magnesium transporter 1 | Pole registreeritud | Esineb 1 haiguses |
| MYCMYC proto-oncogene, bHLH transcription factor | Pole registreeritud | Esineb 1 haiguses |
| NCF1neutrophil cytosolic factor 1 | Pole registreeritud | Esineb 1 haiguses |
| NCF2neutrophil cytosolic factor 2 | Pole registreeritud | Esineb 1 haiguses |
| NFE2L2NFE2 like bZIP transcription factor 2 | Pole registreeritud | Esineb 1 haiguses |
| ORAI1ORAI calcium release-activated calcium modulator 1 | Pole registreeritud | Esineb 1 haiguses |
| OTULINOTU deubiquitinase with linear linkage specificity | Pole registreeritud | Esineb 1 haiguses |
| PGM3phosphoglucomutase 3 | Pole registreeritud | Esineb 1 haiguses |
| PRPS1phosphoribosyl pyrophosphate synthetase 1 | Pole registreeritud | Esineb 1 haiguses |
| PSTPIP1proline-serine-threonine phosphatase interacting protein 1 | Pole registreeritud | Esineb 1 haiguses |
| RBCK1RANBP2-type and C3HC4-type zinc finger containing 1 | Pole registreeritud | Esineb 1 haiguses |
| SH2D1ASH2 domain containing 1A | Pole registreeritud | Esineb 1 haiguses |
| SP110SP110 nuclear body protein | Pole registreeritud | Esineb 1 haiguses |
| TFRCtransferrin receptor | Pole registreeritud | Esineb 1 haiguses |
| TNFRSF4TNF receptor superfamily member 4 | Pole registreeritud | Esineb 1 haiguses |
| TYK2tyrosine kinase 2 | Pole registreeritud | Esineb 1 haiguses |
| UNC119unc-119 lipid binding chaperone | Pole registreeritud | Esineb 1 haiguses |
| UNGuracil DNA glycosylase | Pole registreeritud | Esineb 1 haiguses |
| XRCC4X-ray repair cross complementing 4 | Pole registreeritud | Esineb 1 haiguses |
Kui sageli see esineb geenist tulenevate seisunditega inimeste seas, kõige sagedamini nende kõigi seas, nagu on märgitud Inimese fenotüübi ontoloogias. Need lehed kirjeldavad tunnuseid ja nende taga olevaid uuringuid; need ei ole diagnoos ning sümptomite kohta tuleks küsida arstilt või geneetilt nõustajalt.
Kitsamad tunnused
Laiemad tunnused
Allikas
- Inimese fenotüübi ontoloogia, versioon 2026-09-01: tunnus, selle nimetused, määratlus ja sellega seotud geenid. Lisateave leiab aadressilt hpo.jax.org.
- Andmeversioon 2026.10.16-c6eea6bf.
Üks test. Vastused kogu eluks.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast