Požymis
Poor speech
Santrauka
- Taip pat vadinama
- Difficulty speaking, Problems speaking
- Kūno sistema
- Abnormality of the nervous system
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Poor speech, and the rest of your genome, with one test.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites
Įsigyti savo Genome Test198 genų susiję su Poor speech
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Poor speech. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| ADKadenosine kinase | Visada | 1 ligoje |
| AHDC1AT-hook DNA binding motif containing 1 | Visada | 1 ligoje |
| APC2APC regulator of Wnt signaling pathway 2 | Visada | 1 ligoje |
| CAMK2Gcalcium/calmodulin dependent protein kinase II gamma | Visada | 1 ligoje |
| CCDC22CCC complex scaffolding subunit CCDC22 | Visada | 1 ligoje |
| HEPHL1hephaestin like 1 | Visada | 1 ligoje |
| HS6ST2heparan sulfate 6-O-sulfotransferase 2 | Visada | 1 ligoje |
| ITPR1inositol 1,4,5-trisphosphate receptor type 1 | Visada | 1 ligoje |
| KMT2Blysine methyltransferase 2B | Visada | 1 ligoje |
| MRPS2mitochondrial ribosomal protein S2 | Visada | 1 ligoje |
| PIGCphosphatidylinositol glycan anchor biosynthesis class C | Visada | 1 ligoje |
| SASS6SAS-6 centriolar assembly protein | Visada | 1 ligoje |
| SGSM3small G protein signaling modulator 3 | Visada | 1 ligoje |
| SNAP25synaptosome associated protein 25 | Visada | 1 ligoje |
| AP1S2adaptor related protein complex 1 subunit sigma 2 | Labai dažnai (80–99%) | 1 ligoje |
| ATP6V0A2ATPase H+ transporting V0 subunit a2 | Labai dažnai (80–99%) | 1 ligoje |
| ATP6V1AATPase H+ transporting V1 subunit A | Labai dažnai (80–99%) | 1 ligoje |
| ATP6V1E1ATPase H+ transporting V1 subunit E1 | Labai dažnai (80–99%) | 1 ligoje |
| CASZ1castor zinc finger 1 | Labai dažnai (80–99%) | 1 ligoje |
| CHMP2Bcharged multivesicular body protein 2B | Labai dažnai (80–99%) | 1 ligoje |
| CTNNB1catenin beta 1 | Labai dažnai (80–99%) | 1 ligoje |
| FMN2formin 2 | Labai dažnai (80–99%) | 1 ligoje |
| GABRDgamma-aminobutyric acid type A receptor subunit delta | Labai dažnai (80–99%) | 1 ligoje |
| GRNgranulin precursor | Labai dažnai (80–99%) | 1 ligoje |
| HDAC8histone deacetylase 8 | Labai dažnai (80–99%) | 1 ligoje |
| HSPG2heparan sulfate proteoglycan 2 | Labai dažnai (80–99%) | 1 ligoje |
| KAT6Alysine acetyltransferase 6A | Labai dažnai (80–99%) | 1 ligoje |
| KCNAB2potassium voltage-gated channel subfamily A regulatory beta subunit 2 | Labai dažnai (80–99%) | 1 ligoje |
| LAS1LLAS1 like ribosome biogenesis factor | Labai dažnai (80–99%) | 1 ligoje |
| LUZP1leucine zipper protein 1 | Labai dažnai (80–99%) | 1 ligoje |
| MAPTmicrotubule associated protein tau | Labai dažnai (80–99%) | 2 ligose |
| MMP23Bmatrix metallopeptidase 23B | Labai dažnai (80–99%) | 1 ligoje |
| PAK3p21 (RAC1) activated kinase 3 | Labai dažnai (80–99%) | 1 ligoje |
| PDPNpodoplanin | Labai dažnai (80–99%) | 1 ligoje |
| PRDM16PR/SET domain 16 | Labai dažnai (80–99%) | 1 ligoje |
| PRKCZprotein kinase C zeta | Labai dažnai (80–99%) | 1 ligoje |
| PSEN1presenilin 1 | Labai dažnai (80–99%) | 1 ligoje |
| REREarginine-glutamic acid dipeptide repeats | Labai dažnai (80–99%) | 1 ligoje |
| SKISKI proto-oncogene | Labai dažnai (80–99%) | 1 ligoje |
| SPENspen family transcriptional repressor | Labai dažnai (80–99%) | 1 ligoje |
Rodyti dar 158 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| SQSTM1sequestosome 1 | Labai dažnai (80–99%) | 1 ligoje |
| TMEM106Btransmembrane protein 106B | Labai dažnai (80–99%) | 1 ligoje |
| TREM2triggering receptor expressed on myeloid cells 2 | Labai dažnai (80–99%) | 1 ligoje |
| TRIOtrio Rho guanine nucleotide exchange factor | Labai dažnai (80–99%) | 2 ligose |
| UBE2Aubiquitin conjugating enzyme E2 A | Labai dažnai (80–99%) | 2 ligose |
| UBE4Bubiquitination factor E4B | Labai dažnai (80–99%) | 1 ligoje |
| VCPvalosin containing protein | Labai dažnai (80–99%) | 1 ligoje |
| AP4B1adaptor related protein complex 4 subunit beta 1 | Dažnai (30–79%) | 1 ligoje |
| AP4E1adaptor related protein complex 4 subunit epsilon 1 | Dažnai (30–79%) | 1 ligoje |
| AP4M1adaptor related protein complex 4 subunit mu 1 | Dažnai (30–79%) | 1 ligoje |
| AP4S1adaptor related protein complex 4 subunit sigma 1 | Dažnai (30–79%) | 1 ligoje |
| ASPAaspartoacylase | Dažnai (30–79%) | 1 ligoje |
| ATAD3AATPase family AAA domain containing 3A | Dažnai (30–79%) | 1 ligoje |
| ATP1A1ATPase Na+/K+ transporting subunit alpha 1 | Dažnai (30–79%) | 1 ligoje |
| BRF1BRF1 general transcription factor IIIB subunit | Dažnai (30–79%) | 1 ligoje |
| CDONcell adhesion associated, oncogene regulated | Dažnai (30–79%) | 4 ligose |
| CNTNAP2contactin associated protein 2 | Dažnai (30–79%) | 2 ligose |
| COG8component of oligomeric golgi complex 8 | Dažnai (30–79%) | 1 ligoje |
| CRIPTOcripto, EGF-CFC family member | Dažnai (30–79%) | 4 ligose |
| DISP1dispatched RND transporter family member 1 | Dažnai (30–79%) | 4 ligose |
| DLL1delta like canonical Notch ligand 1 | Dažnai (30–79%) | 4 ligose |
| DOCK7dedicator of cytokinesis 7 | Dažnai (30–79%) | 1 ligoje |
| DYRK1Adual specificity tyrosine phosphorylation regulated kinase 1A | Dažnai (30–79%) | 1 ligoje |
| EBF3EBF transcription factor 3 | Dažnai (30–79%) | 1 ligoje |
| FDXRferredoxin reductase | Dažnai (30–79%) | 1 ligoje |
| FGF8fibroblast growth factor 8 | Dažnai (30–79%) | 4 ligose |
| FGFR1fibroblast growth factor receptor 1 | Dažnai (30–79%) | 2 ligose |
| FOXH1forkhead box H1 | Dažnai (30–79%) | 4 ligose |
| FOXP2forkhead box P2 | Dažnai (30–79%) | 1 ligoje |
| GAMTguanidinoacetate N-methyltransferase | Dažnai (30–79%) | 1 ligoje |
| GAS1growth arrest specific 1 | Dažnai (30–79%) | 4 ligose |
| GATA4GATA binding protein 4 | Dažnai (30–79%) | 1 ligoje |
| GATAD2BGATA zinc finger domain containing 2B | Dažnai (30–79%) | 2 ligose |
| GLI2GLI family zinc finger 2 | Dažnai (30–79%) | 4 ligose |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Dažnai (30–79%) | 1 ligoje |
| HNRNPKheterogeneous nuclear ribonucleoprotein K | Dažnai (30–79%) | 3 ligose |
| INPP5Einositol polyphosphate-5-phosphatase E | Dažnai (30–79%) | 1 ligoje |
| LRPPRCleucine rich pentatricopeptide repeat containing | Dažnai (30–79%) | 1 ligoje |
| MAB21L1mab-21 like 1 | Dažnai (30–79%) | 1 ligoje |
| MAN1B1mannosidase alpha class 1B member 1 | Dažnai (30–79%) | 1 ligoje |
| MED13Lmediator complex subunit 13L | Dažnai (30–79%) | 2 ligose |
| MED25mediator complex subunit 25 | Dažnai (30–79%) | 1 ligoje |
| MID2midline 2 | Dažnai (30–79%) | 1 ligoje |
| NGLY1N-glycanase 1 | Dažnai (30–79%) | 1 ligoje |
| NODALnodal growth differentiation factor | Dažnai (30–79%) | 4 ligose |
| OPHN1oligophrenin 1 | Dažnai (30–79%) | 1 ligoje |
| PPP1R15Bprotein phosphatase 1 regulatory subunit 15B | Dažnai (30–79%) | 1 ligoje |
| PPP2R1Aprotein phosphatase 2 scaffold subunit Aalpha | Dažnai (30–79%) | 1 ligoje |
| PPP2R5Dprotein phosphatase 2 regulatory subunit B'delta | Dažnai (30–79%) | 1 ligoje |
| PTCH1patched 1 | Dažnai (30–79%) | 4 ligose |
| PUS3pseudouridine synthase 3 | Dažnai (30–79%) | 1 ligoje |
| RAC1Rac family small GTPase 1 | Dažnai (30–79%) | 1 ligoje |
| RILPL1Rab interacting lysosomal protein like 1 | Dažnai (30–79%) | 1 ligoje |
| RTTNrotatin | Dažnai (30–79%) | 2 ligose |
| SHHsonic hedgehog signaling molecule | Dažnai (30–79%) | 4 ligose |
| SIX3SIX homeobox 3 | Dažnai (30–79%) | 4 ligose |
| SLC19A3solute carrier family 19 member 3 | Dažnai (30–79%) | 1 ligoje |
| SLC39A14solute carrier family 39 member 14 | Dažnai (30–79%) | 1 ligoje |
| SLC6A17solute carrier family 6 member 17 | Dažnai (30–79%) | 1 ligoje |
| STILSTIL centriolar assembly protein | Dažnai (30–79%) | 4 ligose |
| SYNGAP1synaptic Ras GTPase activating protein 1 | Dažnai (30–79%) | 1 ligoje |
| TAF2TATA-box binding protein associated factor 2 | Dažnai (30–79%) | 1 ligoje |
| TBCDtubulin folding cofactor D | Dažnai (30–79%) | 1 ligoje |
| TELO2telomere maintenance 2 | Dažnai (30–79%) | 1 ligoje |
| TGIF1TGFB induced factor homeobox 1 | Dažnai (30–79%) | 4 ligose |
| TRAPPC10trafficking protein particle complex subunit 10 | Dažnai (30–79%) | 1 ligoje |
| TRMT10AtRNA methyltransferase 10A | Dažnai (30–79%) | 1 ligoje |
| TRMT5tRNA methyltransferase 5 | Dažnai (30–79%) | 1 ligoje |
| TUBB3tubulin beta 3 class III | Dažnai (30–79%) | 1 ligoje |
| UBE3Aubiquitin protein ligase E3A | Dažnai (30–79%) | 3 ligose |
| VPS11VPS11 core subunit of CORVET and HOPS complexes | Dažnai (30–79%) | 2 ligose |
| WDR45WD repeat domain 45 | Dažnai (30–79%) | 2 ligose |
| YME1L1YME1 like 1 ATPase | Dažnai (30–79%) | 1 ligoje |
| ZIC2Zic family zinc finger 2 | Dažnai (30–79%) | 4 ligose |
| ALDH3A2aldehyde dehydrogenase 3 family member A2 | Kartais (5–29%) | 1 ligoje |
| ATP10AATPase phospholipid transporting 10A (putative) | Kartais (5–29%) | 1 ligoje |
| ATP6V1B2ATPase H+ transporting V1 subunit B2 | Kartais (5–29%) | 1 ligoje |
| CDC42cell division cycle 42 | Kartais (5–29%) | 1 ligoje |
| CHSY1chondroitin sulfate synthase 1 | Kartais (5–29%) | 1 ligoje |
| CLIC2CLIC family member 2 | Kartais (5–29%) | 1 ligoje |
| DAG1dystroglycan 1 | Kartais (5–29%) | 1 ligoje |
| DYMdymeclin | Kartais (5–29%) | 1 ligoje |
| FKRPfukutin related protein | Kartais (5–29%) | 1 ligoje |
| FRMD4AFERM domain containing 4A | Kartais (5–29%) | 1 ligoje |
| GMPPBGDP-mannose pyrophosphorylase B | Kartais (5–29%) | 1 ligoje |
| IFNGinterferon gamma | Kartais (5–29%) | 1 ligoje |
| KIF15kinesin family member 15 | Kartais (5–29%) | 1 ligoje |
| LARGE1LARGE xylosyl- and glucuronyltransferase 1 | Kartais (5–29%) | 1 ligoje |
| MID1midline 1 | Kartais (5–29%) | 1 ligoje |
| MTO1mitochondrial tRNA translation optimization 1 | Kartais (5–29%) | 2 ligose |
| NAA20N-alpha-acetyltransferase 20, NatB catalytic subunit | Kartais (5–29%) | 1 ligoje |
| NAGSN-acetylglutamate synthase | Kartais (5–29%) | 1 ligoje |
| NONOnon-POU domain containing octamer binding | Kartais (5–29%) | 1 ligoje |
| OCA2OCA2 melanosomal transmembrane protein | Kartais (5–29%) | 1 ligoje |
| ODC1ornithine decarboxylase 1 | Kartais (5–29%) | 1 ligoje |
| PLCH1phospholipase C eta 1 | Kartais (5–29%) | 1 ligoje |
| POMT1protein O-mannosyltransferase 1 | Kartais (5–29%) | 1 ligoje |
| POMT2protein O-mannosyltransferase 2 | Kartais (5–29%) | 1 ligoje |
| PYCR2pyrroline-5-carboxylate reductase 2 | Kartais (5–29%) | 1 ligoje |
| SARDHsarcosine dehydrogenase | Kartais (5–29%) | 1 ligoje |
| SATB2SATB homeobox 2 | Kartais (5–29%) | 1 ligoje |
| SLC39A8solute carrier family 39 member 8 | Kartais (5–29%) | 1 ligoje |
| SMC1Astructural maintenance of chromosomes 1A | Kartais (5–29%) | 2 ligose |
| SNRPNsmall nuclear ribonucleoprotein polypeptide N | Kartais (5–29%) | 1 ligoje |
| STAG2STAG2 cohesin complex component | Kartais (5–29%) | 2 ligose |
| SYT1synaptotagmin 1 | Kartais (5–29%) | 1 ligoje |
| TSC1TSC complex subunit 1 | Kartais (5–29%) | 1 ligoje |
| TSC2TSC complex subunit 2 | Kartais (5–29%) | 1 ligoje |
| ZNF148zinc finger protein 148 | Kartais (5–29%) | 1 ligoje |
| ZEB2zinc finger E-box binding homeobox 2 | Retai (1–4 %) | 2 ligose |
| ADPRSADP-ribosylserine hydrolase | Neužfiksuota | 1 ligoje |
| ALG9ALG9 alpha-1,2-mannosyltransferase | Neužfiksuota | 1 ligoje |
| CADcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | Neužfiksuota | 1 ligoje |
| CHKBcholine kinase beta | Neužfiksuota | 1 ligoje |
| CHMP1Acharged multivesicular body protein 1A | Neužfiksuota | 1 ligoje |
| CICcapicua transcriptional repressor | Neužfiksuota | 1 ligoje |
| CSF1Rcolony stimulating factor 1 receptor | Neužfiksuota | 1 ligoje |
| DIAPH1diaphanous related formin 1 | Neužfiksuota | 1 ligoje |
| DLATdihydrolipoamide S-acetyltransferase | Neužfiksuota | 1 ligoje |
| EIF2S3eukaryotic translation initiation factor 2 subunit gamma | Neužfiksuota | 1 ligoje |
| EXT2exostosin glycosyltransferase 2 | Neužfiksuota | 1 ligoje |
| FBXL3F-box and leucine rich repeat protein 3 | Neužfiksuota | 1 ligoje |
| FGF12fibroblast growth factor 12 | Neužfiksuota | 1 ligoje |
| FOXRED1FAD dependent oxidoreductase domain containing 1 | Neužfiksuota | 1 ligoje |
| GJC2gap junction protein gamma 2 | Neužfiksuota | 1 ligoje |
| GPR88G protein-coupled receptor 88 | Neužfiksuota | 1 ligoje |
| GUSBglucuronidase beta | Neužfiksuota | 1 ligoje |
| IQSEC2IQ motif and Sec7 domain ArfGEF 2 | Neužfiksuota | 1 ligoje |
| KANSL1KAT8 regulatory NSL complex subunit 1 | Neužfiksuota | 1 ligoje |
| KIF14kinesin family member 14 | Neužfiksuota | 1 ligoje |
| NALCNsodium leak channel, non-selective | Neužfiksuota | 1 ligoje |
| NDST1N-deacetylase and N-sulfotransferase 1 | Neužfiksuota | 1 ligoje |
| NDUFA13NADH:ubiquinone oxidoreductase subunit A13 | Neužfiksuota | 1 ligoje |
| NDUFA6NADH:ubiquinone oxidoreductase subunit A6 | Neužfiksuota | 1 ligoje |
| NDUFS1NADH:ubiquinone oxidoreductase core subunit S1 | Neužfiksuota | 1 ligoje |
| NUBPLNUBP iron-sulfur cluster assembly factor, mitochondrial | Neužfiksuota | 1 ligoje |
| PAK1p21 (RAC1) activated kinase 1 | Neužfiksuota | 1 ligoje |
| PIGHphosphatidylinositol glycan anchor biosynthesis class H | Neužfiksuota | 1 ligoje |
| PLPBPpyridoxal phosphate binding protein | Neužfiksuota | 1 ligoje |
| POMKprotein O-mannose kinase | Neužfiksuota | 1 ligoje |
| RAB39BRAB39B, member RAS oncogene family | Neužfiksuota | 1 ligoje |
| RLIMring finger protein, LIM domain interacting | Neužfiksuota | 1 ligoje |
| RNASET2ribonuclease T2 | Neužfiksuota | 1 ligoje |
| SETSET nuclear proto-oncogene | Neužfiksuota | 1 ligoje |
| SLC35A1solute carrier family 35 member A1 | Neužfiksuota | 1 ligoje |
| SMARCA2SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 | Neužfiksuota | 1 ligoje |
| SMC3structural maintenance of chromosomes 3 | Neužfiksuota | 1 ligoje |
| SOBPsine oculis binding protein homolog | Neužfiksuota | 1 ligoje |
| TAF6TATA-box binding protein associated factor 6 | Neužfiksuota | 1 ligoje |
| TBCKTBC1 domain containing kinase | Neužfiksuota | 1 ligoje |
| TRAPPC11trafficking protein particle complex subunit 11 | Neužfiksuota | 1 ligoje |
| TRRAPtransformation/transcription domain associated protein | Neužfiksuota | 1 ligoje |
| TUBB4Atubulin beta 4A class IVa | Neužfiksuota | 1 ligoje |
| UNC80unc-80 subunit of NALCN channel complex | Neužfiksuota | 1 ligoje |
| UQCC2ubiquinol-cytochrome c reductase complex assembly factor 2 | Neužfiksuota | 1 ligoje |
| VLDLRvery low density lipoprotein receptor | Neužfiksuota | 1 ligoje |
| WDR73WD repeat domain 73 | Neužfiksuota | 1 ligoje |
| WIPI2WD repeat domain, phosphoinositide interacting 2 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
Platesni požymiai
Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
Vienas testas. Atsakymai visam gyvenimui.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites