Cecha
Brain degeneration
Nazwa kliniczna: Brain atrophy
Partial or complete wasting (loss) of brain tissue that was once present.
Podsumowanie
- Znana także jako
- Brain wasting
- Układ organizmu
- Abnormality of the nervous system
Genom referencyjnyGRCh38hg38
Pozycje na stronach genów i wariantów zależą od tego wyboru, w tej przeglądarce.
Read the genes linked to Brain degeneration, and the rest of your genome, with one test.
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Zamawiam Genome Test202 genów powiązanych z Brain degeneration
Zmiany w tych genach powodują rzadkie choroby, w których występuje Brain degeneration. Większość osób z tą cechą nie ma żadnej z tych chorób, a gen z tej listy nic nie mówi o czyimkolwiek własnym genomie.
| Gen | Jak często występuje | Choroby |
|---|---|---|
| ATP5POATP synthase peripheral stalk subunit OSCP | Zawsze | W 1 chorobie |
| CBScystathionine beta-synthase | Zawsze | W 1 chorobie |
| COX11cytochrome c oxidase copper chaperone COX11 | Zawsze | W 1 chorobie |
| COX8Acytochrome c oxidase subunit 8A | Zawsze | W 1 chorobie |
| DNAJB4DnaJ heat shock protein family (Hsp40) member B4 | Zawsze | W 1 chorobie |
| FBXO28F-box protein 28 | Zawsze | W 2 chorobach |
| GLULglutamate-ammonia ligase | Zawsze | W 1 chorobie |
| GOLGA2golgin A2 | Zawsze | W 1 chorobie |
| GTPBP2GTP binding protein 2 | Zawsze | W 1 chorobie |
| HTRA1HtrA serine peptidase 1 | Zawsze | W 1 chorobie |
| INTS11integrator complex subunit 11 | Zawsze | W 1 chorobie |
| KCNT1potassium sodium-activated channel subfamily T member 1 | Zawsze | W 1 chorobie |
| LRP12LDL receptor related protein 12 | Zawsze | W 1 chorobie |
| MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2 | Zawsze | W 2 chorobach |
| MRAPmelanocortin 2 receptor accessory protein | Zawsze | W 1 chorobie |
| MYORGmyogenesis regulating glycosidase | Zawsze | W 1 chorobie |
| NDUFA11NADH:ubiquinone oxidoreductase subunit A11 | Zawsze | W 1 chorobie |
| NDUFV1NADH:ubiquinone oxidoreductase core subunit V1 | Zawsze | W 1 chorobie |
| NECAP1NECAP endocytosis associated 1 | Zawsze | W 2 chorobach |
| NMNAT1nicotinamide nucleotide adenylyltransferase 1 | Zawsze | W 1 chorobie |
| NOTCH3notch receptor 3 | Zawsze | W 2 chorobach |
| NUP133nucleoporin 133 | Zawsze | W 1 chorobie |
| PHGDHphosphoglycerate dehydrogenase | Zawsze | W 1 chorobie |
| RFXANKregulatory factor X associated ankyrin containing protein | Zawsze | W 1 chorobie |
| RFXAPregulatory factor X associated protein | Zawsze | W 1 chorobie |
| RNU4-2RNA, U4 small nuclear 2 | Zawsze | W 1 chorobie |
| SCO1synthesis of cytochrome C oxidase 1 | Zawsze | W 1 chorobie |
| VCPvalosin containing protein | Zawsze | W 2 chorobach |
| VPS11VPS11 core subunit of CORVET and HOPS complexes | Zawsze | W 1 chorobie |
| AFF3ALF transcription elongation factor 3 | Bardzo często (80–99%) | W 1 chorobie |
| CHMP2Bcharged multivesicular body protein 2B | Bardzo często (80–99%) | W 1 chorobie |
| COG7component of oligomeric golgi complex 7 | Bardzo często (80–99%) | W 1 chorobie |
| EMC1ER membrane protein complex subunit 1 | Bardzo często (80–99%) | W 1 chorobie |
| FGFR3fibroblast growth factor receptor 3 | Bardzo często (80–99%) | W 1 chorobie |
| GRNgranulin precursor | Bardzo często (80–99%) | W 1 chorobie |
| MAPTmicrotubule associated protein tau | Bardzo często (80–99%) | W 1 chorobie |
| PSEN1presenilin 1 | Bardzo często (80–99%) | W 1 chorobie |
| SCO2synthesis of cytochrome C oxidase 2 | Bardzo często (80–99%) | W 1 chorobie |
| TMEM106Btransmembrane protein 106B | Bardzo często (80–99%) | W 1 chorobie |
| TREM2triggering receptor expressed on myeloid cells 2 | Bardzo często (80–99%) | W 1 chorobie |
Pokaż jeszcze 162 genów
| Gen | Jak często występuje | Choroby |
|---|---|---|
| ZNF335zinc finger protein 335 | Bardzo często (80–99%) | W 1 chorobie |
| ADARadenosine deaminase RNA specific | Często (30–79%) | W 1 chorobie |
| ARHGEF15Rho guanine nucleotide exchange factor 15 | Często (30–79%) | W 1 chorobie |
| BORCS5BLOC-1 related complex subunit 5 | Często (30–79%) | W 1 chorobie |
| COG1component of oligomeric golgi complex 1 | Często (30–79%) | W 1 chorobie |
| COX16cytochrome c oxidase assembly factor COX16 | Często (30–79%) | W 1 chorobie |
| DNAJC6DnaJ heat shock protein family (Hsp40) member C6 | Często (30–79%) | W 1 chorobie |
| DNM1dynamin 1 | Często (30–79%) | W 2 chorobach |
| ECHS1enoyl-CoA hydratase, short chain 1 | Często (30–79%) | W 1 chorobie |
| ELOVL4ELOVL fatty acid elongase 4 | Często (30–79%) | W 1 chorobie |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Często (30–79%) | W 2 chorobach |
| ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Często (30–79%) | W 1 chorobie |
| GEMIN4gem nuclear organelle associated protein 4 | Często (30–79%) | W 1 chorobie |
| GRID2glutamate ionotropic receptor delta type subunit 2 | Często (30–79%) | W 1 chorobie |
| HID1HID1 domain containing | Często (30–79%) | W 1 chorobie |
| HNRNPA1heterogeneous nuclear ribonucleoprotein A1 | Często (30–79%) | W 1 chorobie |
| HNRNPA2B1heterogeneous nuclear ribonucleoprotein A2/B1 | Często (30–79%) | W 1 chorobie |
| IFIH1interferon induced with helicase C domain 1 | Często (30–79%) | W 1 chorobie |
| LSM11LSM11, U7 small nuclear RNA associated | Często (30–79%) | W 1 chorobie |
| MED11mediator complex subunit 11 | Często (30–79%) | W 1 chorobie |
| MTRR5-methyltetrahydrofolate-homocysteine methyltransferase reductase | Często (30–79%) | W 1 chorobie |
| NKX6-2NK6 homeobox 2 | Często (30–79%) | W 1 chorobie |
| NTNG2netrin G2 | Często (30–79%) | W 1 chorobie |
| PGAP2post-GPI attachment to proteins 2 | Często (30–79%) | W 1 chorobie |
| PODXLpodocalyxin like | Często (30–79%) | W 1 chorobie |
| PURApurine rich element binding protein A | Często (30–79%) | W 1 chorobie |
| RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1 | Często (30–79%) | W 1 chorobie |
| RARS2arginyl-tRNA synthetase 2, mitochondrial | Często (30–79%) | W 1 chorobie |
| RBMXRNA binding motif protein X-linked | Często (30–79%) | W 1 chorobie |
| RNASEH2Aribonuclease H2 subunit A | Często (30–79%) | W 1 chorobie |
| RNASEH2Bribonuclease H2 subunit B | Często (30–79%) | W 1 chorobie |
| RNASEH2Cribonuclease H2 subunit C | Często (30–79%) | W 1 chorobie |
| RNU7-1RNA, U7 small nuclear 1 | Często (30–79%) | W 1 chorobie |
| RUSC2RUN and SH3 domain containing 2 | Często (30–79%) | W 1 chorobie |
| SAMHD1SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 | Często (30–79%) | W 1 chorobie |
| SERAC1serine active site containing 1 | Często (30–79%) | W 1 chorobie |
| SLC16A2solute carrier family 16 member 2 | Często (30–79%) | W 1 chorobie |
| SLC1A4solute carrier family 1 member 4 | Często (30–79%) | W 1 chorobie |
| SLC25A22solute carrier family 25 member 22 | Często (30–79%) | W 1 chorobie |
| SMG9SMG9 nonsense mediated mRNA decay factor | Często (30–79%) | W 1 chorobie |
| SYNGAP1synaptic Ras GTPase activating protein 1 | Często (30–79%) | W 2 chorobach |
| SYNJ1synaptojanin 1 | Często (30–79%) | W 2 chorobach |
| TPRKBTP53RK binding protein | Często (30–79%) | W 1 chorobie |
| TREX1three prime repair exonuclease 1 | Często (30–79%) | W 1 chorobie |
| TRMT5tRNA methyltransferase 5 | Często (30–79%) | W 1 chorobie |
| VPS33AVPS33A core subunit of CORVET and HOPS complexes | Często (30–79%) | W 2 chorobach |
| WDR73WD repeat domain 73 | Często (30–79%) | W 1 chorobie |
| ZNF592zinc finger protein 592 | Często (30–79%) | W 1 chorobie |
| ZNF668zinc finger protein 668 | Często (30–79%) | W 1 chorobie |
| AARS1alanyl-tRNA synthetase 1 | Czasami (5–29%) | W 1 chorobie |
| ACTL6Bactin like 6B | Czasami (5–29%) | W 1 chorobie |
| ADAT3adenosine deaminase tRNA specific 3 | Czasami (5–29%) | W 2 chorobach |
| AFG2AAAA ATPase AFG2A | Czasami (5–29%) | W 1 chorobie |
| ALDH7A1aldehyde dehydrogenase 7 family member A1 | Czasami (5–29%) | W 1 chorobie |
| ALG3ALG3 alpha-1,3- mannosyltransferase | Czasami (5–29%) | W 1 chorobie |
| AP3B2adaptor related protein complex 3 subunit beta 2 | Czasami (5–29%) | W 1 chorobie |
| ASAH1N-acylsphingosine amidohydrolase 1 | Czasami (5–29%) | W 1 chorobie |
| ATP1A2ATPase Na+/K+ transporting subunit alpha 2 | Czasami (5–29%) | W 1 chorobie |
| ATP1A3ATPase Na+/K+ transporting subunit alpha 3 | Czasami (5–29%) | W 1 chorobie |
| ATP6V1AATPase H+ transporting V1 subunit A | Czasami (5–29%) | W 1 chorobie |
| AXIN1axin 1 | Czasami (5–29%) | W 1 chorobie |
| BCAP31B cell receptor associated protein 31 | Czasami (5–29%) | W 1 chorobie |
| CACNA1Acalcium voltage-gated channel subunit alpha1 A | Czasami (5–29%) | W 1 chorobie |
| CACNA1Bcalcium voltage-gated channel subunit alpha1 B | Czasami (5–29%) | W 1 chorobie |
| CACNA1Icalcium voltage-gated channel subunit alpha1 I | Czasami (5–29%) | W 1 chorobie |
| CACNA2D1calcium voltage-gated channel auxiliary subunit alpha2delta 1 | Czasami (5–29%) | W 1 chorobie |
| CDK19cyclin dependent kinase 19 | Czasami (5–29%) | W 1 chorobie |
| CELF2CUGBP Elav-like family member 2 | Czasami (5–29%) | W 1 chorobie |
| CHAMP1chromosome alignment maintaining phosphoprotein 1 | Czasami (5–29%) | W 1 chorobie |
| CLTCclathrin heavy chain | Czasami (5–29%) | W 1 chorobie |
| CNKSR2connector enhancer of kinase suppressor of Ras 2 | Czasami (5–29%) | W 1 chorobie |
| COG5component of oligomeric golgi complex 5 | Czasami (5–29%) | W 1 chorobie |
| CYFIP2cytoplasmic FMR1 interacting protein 2 | Czasami (5–29%) | W 1 chorobie |
| DALRD3DALR anticodon binding domain containing 3 | Czasami (5–29%) | W 1 chorobie |
| DEPDC5DEP domain containing 5, GATOR1 subcomplex subunit | Czasami (5–29%) | W 1 chorobie |
| DHDDSdehydrodolichyl diphosphate synthase subunit | Czasami (5–29%) | W 1 chorobie |
| DIAPH1diaphanous related formin 1 | Czasami (5–29%) | W 1 chorobie |
| DOT1LDOT1 like histone lysine methyltransferase | Czasami (5–29%) | W 1 chorobie |
| DPH5diphthamide biosynthesis 5 | Czasami (5–29%) | W 1 chorobie |
| EEF1A2eukaryotic translation elongation factor 1 alpha 2 | Czasami (5–29%) | W 1 chorobie |
| EPM2AEPM2A glucan phosphatase, laforin | Czasami (5–29%) | W 1 chorobie |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Czasami (5–29%) | W 1 chorobie |
| FBXO22F-box protein 22 | Czasami (5–29%) | W 1 chorobie |
| FGF12fibroblast growth factor 12 | Czasami (5–29%) | W 1 chorobie |
| FOXG1forkhead box G1 | Czasami (5–29%) | W 1 chorobie |
| FTOFTO alpha-ketoglutarate dependent dioxygenase | Czasami (5–29%) | W 1 chorobie |
| FZR1fizzy and cell division cycle 20 related 1 | Czasami (5–29%) | W 1 chorobie |
| GABBR2gamma-aminobutyric acid type B receptor subunit 2 | Czasami (5–29%) | W 1 chorobie |
| GABRA2gamma-aminobutyric acid type A receptor subunit alpha2 | Czasami (5–29%) | W 1 chorobie |
| GABRA5gamma-aminobutyric acid type A receptor subunit alpha5 | Czasami (5–29%) | W 1 chorobie |
| GABRB2gamma-aminobutyric acid type A receptor subunit beta2 | Czasami (5–29%) | W 1 chorobie |
| GABRG2gamma-aminobutyric acid type A receptor subunit gamma2 | Czasami (5–29%) | W 1 chorobie |
| GLYCTKglycerate kinase | Czasami (5–29%) | W 1 chorobie |
| GRIN2Dglutamate ionotropic receptor NMDA type subunit 2D | Czasami (5–29%) | W 1 chorobie |
| HCN1hyperpolarization activated cyclic nucleotide gated potassium channel 1 | Czasami (5–29%) | W 1 chorobie |
| KCNA2potassium voltage-gated channel subfamily A member 2 | Czasami (5–29%) | W 1 chorobie |
| KCNB1potassium voltage-gated channel subfamily B member 1 | Czasami (5–29%) | W 1 chorobie |
| KCNC2potassium voltage-gated channel subfamily C member 2 | Czasami (5–29%) | W 1 chorobie |
| KCNH5potassium voltage-gated channel subfamily H member 5 | Czasami (5–29%) | W 1 chorobie |
| KCNQ5potassium voltage-gated channel subfamily Q member 5 | Czasami (5–29%) | W 1 chorobie |
| LYSTlysosomal trafficking regulator | Czasami (5–29%) | W 1 chorobie |
| MGAT2alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | Czasami (5–29%) | W 1 chorobie |
| MORC2MORC family CW-type zinc finger 2 | Czasami (5–29%) | W 1 chorobie |
| MT-CO1mitochondrially encoded cytochrome c oxidase I | Czasami (5–29%) | W 1 chorobie |
| MT-CO2mitochondrially encoded cytochrome c oxidase II | Czasami (5–29%) | W 1 chorobie |
| MT-CO3mitochondrially encoded cytochrome c oxidase III | Czasami (5–29%) | W 1 chorobie |
| MT-ND1mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | Czasami (5–29%) | W 1 chorobie |
| MT-ND4mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | Czasami (5–29%) | W 1 chorobie |
| MT-ND5mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | Czasami (5–29%) | W 1 chorobie |
| MT-ND6mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | Czasami (5–29%) | W 1 chorobie |
| MT-TFmitochondrially encoded tRNA-Phe (UUU/C) | Czasami (5–29%) | W 1 chorobie |
| MT-THmitochondrially encoded tRNA-His (CAU/C) | Czasami (5–29%) | W 1 chorobie |
| MT-TL1mitochondrially encoded tRNA-Leu (UUA/G) 1 | Czasami (5–29%) | W 1 chorobie |
| MT-TQmitochondrially encoded tRNA-Gln (CAA/G) | Czasami (5–29%) | W 1 chorobie |
| MT-TS1mitochondrially encoded tRNA-Ser (UCN) 1 | Czasami (5–29%) | W 1 chorobie |
| MT-TS2mitochondrially encoded tRNA-Ser (AGU/C) 2 | Czasami (5–29%) | W 1 chorobie |
| MT-TWmitochondrially encoded tRNA-Trp (UGA/G) | Czasami (5–29%) | W 1 chorobie |
| MTHFRmethylenetetrahydrofolate reductase | Czasami (5–29%) | W 1 chorobie |
| NARS1asparaginyl-tRNA synthetase 1 | Czasami (5–29%) | W 1 chorobie |
| NAXENAD(P)HX epimerase | Czasami (5–29%) | W 2 chorobach |
| NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1 | Czasami (5–29%) | W 1 chorobie |
| NTRK2neurotrophic receptor tyrosine kinase 2 | Czasami (5–29%) | W 1 chorobie |
| NUS1NUS1 dehydrodolichyl diphosphate synthase subunit | Czasami (5–29%) | W 1 chorobie |
| PACS2phosphofurin acidic cluster sorting protein 2 | Czasami (5–29%) | W 1 chorobie |
| PARS2prolyl-tRNA synthetase 2, mitochondrial | Czasami (5–29%) | W 1 chorobie |
| PEX16peroxisomal biogenesis factor 16 | Czasami (5–29%) | W 1 chorobie |
| PLPBPpyridoxal phosphate binding protein | Czasami (5–29%) | W 2 chorobach |
| PPP3CAprotein phosphatase 3 catalytic subunit alpha | Czasami (5–29%) | W 1 chorobie |
| PRKDCprotein kinase, DNA-activated, catalytic subunit | Czasami (5–29%) | W 1 chorobie |
| PUS7pseudouridine synthase 7 | Czasami (5–29%) | W 1 chorobie |
| SBF1SET binding factor 1 | Czasami (5–29%) | W 1 chorobie |
| SCN1Asodium voltage-gated channel alpha subunit 1 | Czasami (5–29%) | W 1 chorobie |
| SCN3Asodium voltage-gated channel alpha subunit 3 | Czasami (5–29%) | W 1 chorobie |
| SCN8Asodium voltage-gated channel alpha subunit 8 | Czasami (5–29%) | W 1 chorobie |
| SLC13A5solute carrier family 13 member 5 | Czasami (5–29%) | W 1 chorobie |
| SLC1A2solute carrier family 1 member 2 | Czasami (5–29%) | W 1 chorobie |
| SLC38A3solute carrier family 38 member 3 | Czasami (5–29%) | W 1 chorobie |
| SMG8SMG8 nonsense mediated mRNA decay factor | Czasami (5–29%) | W 1 chorobie |
| STAG1STAG1 cohesin complex component | Czasami (5–29%) | W 1 chorobie |
| SZT2SZT2 subunit of KICSTOR complex | Czasami (5–29%) | W 1 chorobie |
| TRAK1trafficking kinesin protein 1 | Czasami (5–29%) | W 1 chorobie |
| UBA5ubiquitin like modifier activating enzyme 5 | Czasami (5–29%) | W 1 chorobie |
| UFSP2UFM1 specific peptidase 2 | Czasami (5–29%) | W 1 chorobie |
| USP9Xubiquitin specific peptidase 9 X-linked | Czasami (5–29%) | W 1 chorobie |
| YME1L1YME1 like 1 ATPase | Czasami (5–29%) | W 1 chorobie |
| YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma | Czasami (5–29%) | W 1 chorobie |
| ACBD6acyl-CoA binding domain containing 6 | Rzadko (1–4%) | W 1 chorobie |
| ALDH3A2aldehyde dehydrogenase 3 family member A2 | Rzadko (1–4%) | W 1 chorobie |
| ASPAaspartoacylase | Nie odnotowano | W 1 chorobie |
| EXOC8exocyst complex component 8 | Nie odnotowano | W 1 chorobie |
| ITPAinosine triphosphatase | Nie odnotowano | W 1 chorobie |
| KIF7kinesin family member 7 | Nie odnotowano | W 1 chorobie |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Nie odnotowano | W 1 chorobie |
| NDUFS1NADH:ubiquinone oxidoreductase core subunit S1 | Nie odnotowano | W 1 chorobie |
| NDUFS2NADH:ubiquinone oxidoreductase core subunit S2 | Nie odnotowano | W 1 chorobie |
| NDUFV2NADH:ubiquinone oxidoreductase core subunit V2 | Nie odnotowano | W 1 chorobie |
| PDE10Aphosphodiesterase 10A | Nie odnotowano | W 1 chorobie |
| TBC1D32TBC1 domain family member 32 | Nie odnotowano | W 1 chorobie |
| TBCKTBC1 domain containing kinase | Nie odnotowano | W 1 chorobie |
| TRAPPC4trafficking protein particle complex subunit 4 | Nie odnotowano | W 1 chorobie |
| WDR81WD repeat domain 81 | Nie odnotowano | W 1 chorobie |
| ZC4H2zinc finger C4H2-type containing | Nie odnotowano | W 1 chorobie |
Jak często występuje wśród osób z jedną z chorób związanych z tym genem, najczęściej spośród wszystkich, według danych Human Phenotype Ontology. Te strony opisują cechy i badania, na których się opierają; nie są diagnozą, a w sprawie objawów należy zwrócić się do lekarza lub doradcy genetycznego.
Cechy podrzędne
Cechy nadrzędne
Skąd pochodzą te dane
- Human Phenotype Ontology, wydanie 2026-09-01: cecha, jej nazwy, definicja oraz geny z nią powiązane. Więcej informacji znajdą Państwo na stronie hpo.jax.org.
- Wydanie danych 2026.10.16-c6eea6bf.
Jeden test. Odpowiedzi na całe życie.
Od 449 $Bezpłatna wysyłka · Wyniki w ciągu 6–8 tygodni