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PrisijungtiKlaustiSekvenuokite savo genomą↗
Požymis
Decreased activity of gonads
Klinikinis pavadinimas: Hypogonadism
A decreased functionality of the gonad.
Santrauka
AtlasKam padedameMūsų mokslasProduktaiRezultatai
PrisijungtiKlaustiSekvenuokite savo genomą↗
Ši puslapis kaip duomenys
Norėdami perskaityti jį kaip JSON, pridėkite .json prie puslapio adreso arba nurodykite application/json.
library(jsonlite)
url <- "https://dantelabs.com/traits/hypogonadism.json"
page <- fromJSON(url)
page$trait$nameDecreased activity of gonadsHP:0000135
AtlasKam padedameMūsų mokslasProduktaiRezultatai
PrisijungtiKlaustiSekvenuokite savo genomą↗
Vienu tyrimu sužinokite genus, susijusius su Decreased activity of gonads, ir kitą jūsų genomo dalį.
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Įsigyti savo Genome Test171 genas susijęs su Decreased activity of gonads
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Decreased activity of gonads. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| ALG1ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase | Visada | 1 ligoje |
| BBS12Bardet-Biedl syndrome 12 | Visada | 2 ligose |
| BBS2Bardet-Biedl syndrome 2 | Visada | 2 ligose |
| BBS5Bardet-Biedl syndrome 5 | Visada | 2 ligose |
| BBS7Bardet-Biedl syndrome 7 | Visada | 2 ligose |
| DCAF17DDB1 and CUL4 associated factor 17 | Visada | 2 ligose |
| FANCBFA complementation group B | Visada | 2 ligose |
| FEZF1FEZ family zinc finger 1 | Visada | 1 ligoje |
| HAMPhepcidin antimicrobial peptide | Visada | 2 ligose |
| IFT74intraflagellar transport 74 | Visada | 2 ligose |
| LZTFL1leucine zipper transcription factor like 1 | Visada | 2 ligose |
| MDM2MDM2 proto-oncogene | Visada | 1 ligoje |
| PNPLA6patatin like domain 6, lysophospholipase | Visada | 3 ligose |
| SLC30A7solute carrier family 30 member 7 | Visada | 1 ligoje |
| STEAP3STEAP3 metalloreductase | Visada | 2 ligose |
| TP53tumor protein p53 | Visada | 1 ligoje |
| AIPAHR interacting HSP90 co-chaperone | Labai dažnai (80–99%) | 1 ligoje |
| ALX4ALX homeobox 4 | Labai dažnai (80–99%) | 1 ligoje |
| ANK1ankyrin 1 | Labai dažnai (80–99%) | 1 ligoje |
| CAMKMTcalmodulin-lysine N-methyltransferase | Labai dažnai (80–99%) | 1 ligoje |
| CDH23cadherin related 23 | Labai dažnai (80–99%) | 2 ligose |
| CDKN1Ccyclin dependent kinase inhibitor 1C | Labai dažnai (80–99%) | 1 ligoje |
| DDB2damage specific DNA binding protein 2 | Labai dažnai (80–99%) | 1 ligoje |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Labai dažnai (80–99%) | 3 ligose |
| ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit | Labai dažnai (80–99%) | 2 ligose |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Labai dažnai (80–99%) | 2 ligose |
| ERCC5ERCC excision repair 5, endonuclease | Labai dažnai (80–99%) | 2 ligose |
| FMR1fragile X messenger ribonucleoprotein 1 | Labai dažnai (80–99%) | 1 ligoje |
| LMNAlamin A/C | Labai dažnai (80–99%) | 1 ligoje |
| MEN1menin 1 | Labai dažnai (80–99%) | 1 ligoje |
| PEX1peroxisomal biogenesis factor 1 | Labai dažnai (80–99%) | 1 ligoje |
| PEX6peroxisomal biogenesis factor 6 | Labai dažnai (80–99%) | 1 ligoje |
| PHF6PHD finger protein 6 | Labai dažnai (80–99%) | 1 ligoje |
| POLEDNA polymerase epsilon, catalytic subunit | Labai dažnai (80–99%) | 1 ligoje |
| PPM1Bprotein phosphatase, Mg2+/Mn2+ dependent 1B | Labai dažnai (80–99%) | 1 ligoje |
| PREPLprolyl endopeptidase like | Labai dažnai (80–99%) | 1 ligoje |
| RNF216ring finger protein 216 | Labai dažnai (80–99%) | 1 ligoje |
| SIL1SIL1 nucleotide exchange factor | Labai dažnai (80–99%) | 1 ligoje |
| SIM1SIM bHLH transcription factor 1 | Labai dažnai (80–99%) | 1 ligoje |
| SLC3A1solute carrier family 3 member 1 | Labai dažnai (80–99%) | 1 ligoje |
Rodyti dar 131 geną
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| SMCHD1structural maintenance of chromosomes flexible hinge domain containing 1 | Labai dažnai (80–99%) | 1 ligoje |
| TTC8tetratricopeptide repeat domain 8 | Labai dažnai (80–99%) | 2 ligose |
| WRNWRN RecQ like helicase | Labai dažnai (80–99%) | 2 ligose |
| XPAXPA, DNA damage recognition and repair factor | Labai dažnai (80–99%) | 1 ligoje |
| XPCXPC complex subunit, DNA damage recognition and repair factor | Labai dažnai (80–99%) | 1 ligoje |
| ZBTB20zinc finger and BTB domain containing 20 | Labai dažnai (80–99%) | 1 ligoje |
| AIREautoimmune regulator | Dažnai (30–79%) | 2 ligose |
| ARL6ARF like GTPase 6 | Dažnai (30–79%) | 2 ligose |
| BBIP1BBSome interacting protein 1 | Dažnai (30–79%) | 1 ligoje |
| BBS1Bardet-Biedl syndrome 1 | Dažnai (30–79%) | 2 ligose |
| BBS10Bardet-Biedl syndrome 10 | Dažnai (30–79%) | 2 ligose |
| BBS4Bardet-Biedl syndrome 4 | Dažnai (30–79%) | 2 ligose |
| BBS9Bardet-Biedl syndrome 9 | Dažnai (30–79%) | 1 ligoje |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Dažnai (30–79%) | 2 ligose |
| CEP19centrosomal protein 19 | Dažnai (30–79%) | 1 ligoje |
| CEP290centrosomal protein 290 | Dažnai (30–79%) | 1 ligoje |
| CFAP418cilia and flagella associated protein 418 | Dažnai (30–79%) | 1 ligoje |
| CHRNGcholinergic receptor nicotinic gamma subunit | Dažnai (30–79%) | 1 ligoje |
| CTNNB1catenin beta 1 | Dažnai (30–79%) | 1 ligoje |
| ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit | Dažnai (30–79%) | 1 ligoje |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Dažnai (30–79%) | 1 ligoje |
| HJVhemojuvelin BMP co-receptor | Dažnai (30–79%) | 1 ligoje |
| IFT172intraflagellar transport 172 | Dažnai (30–79%) | 1 ligoje |
| IFT27intraflagellar transport 27 | Dažnai (30–79%) | 2 ligose |
| IGF1insulin like growth factor 1 | Dažnai (30–79%) | 1 ligoje |
| MAGEL2MAGE family member L2 | Dažnai (30–79%) | 2 ligose |
| MKKSMKKS centrosomal shuttling protein | Dažnai (30–79%) | 1 ligoje |
| MKS1MKS transition zone complex subunit 1 | Dažnai (30–79%) | 1 ligoje |
| MYH3myosin heavy chain 3 | Dažnai (30–79%) | 1 ligoje |
| NECTIN1nectin cell adhesion molecule 1 | Dažnai (30–79%) | 1 ligoje |
| NPHP1nephrocystin 1 | Dažnai (30–79%) | 1 ligoje |
| SCAPERS-phase cyclin A associated protein in the ER | Dažnai (30–79%) | 1 ligoje |
| SCLT1sodium channel and clathrin linker 1 | Dažnai (30–79%) | 1 ligoje |
| SDCCAG8SHH signaling and ciliogenesis regulator SDCCAG8 | Dažnai (30–79%) | 2 ligose |
| SEMA3Asemaphorin 3A | Dažnai (30–79%) | 1 ligoje |
| SOX10SRY-box transcription factor 10 | Dažnai (30–79%) | 2 ligose |
| TRIM32tripartite motif containing 32 | Dažnai (30–79%) | 2 ligose |
| USP7ubiquitin specific peptidase 7 | Dažnai (30–79%) | 1 ligoje |
| WDPCPWD repeat containing planar cell polarity effector | Dažnai (30–79%) | 1 ligoje |
| AMACRalpha-methylacyl-CoA racemase | Kartais (5–29%) | 1 ligoje |
| ANAPC1anaphase promoting complex subunit 1 | Kartais (5–29%) | 1 ligoje |
| ANTXR1ANTXR cell adhesion molecule 1 | Kartais (5–29%) | 1 ligoje |
| ATP5F1AATP synthase F1 subunit alpha | Kartais (5–29%) | 1 ligoje |
| ATP5F1DATP synthase F1 subunit delta | Kartais (5–29%) | 1 ligoje |
| ATP5F1EATP synthase F1 subunit epsilon | Kartais (5–29%) | 1 ligoje |
| ATP5MKATP synthase membrane subunit k | Kartais (5–29%) | 1 ligoje |
| ATP5POATP synthase peripheral stalk subunit OSCP | Kartais (5–29%) | 1 ligoje |
| ATPAF2ATP synthase mitochondrial F1 complex assembly factor 2 | Kartais (5–29%) | 1 ligoje |
| BCL11ABCL11 transcription factor A | Kartais (5–29%) | 1 ligoje |
| BCS1LBCS1 ubiquinol-cytochrome c reductase complex chaperone | Kartais (5–29%) | 1 ligoje |
| BRCA1BRCA1 DNA repair associated | Kartais (5–29%) | 1 ligoje |
| BRCA2BRCA2 DNA repair associated | Kartais (5–29%) | 1 ligoje |
| BRIP1BRCA1 interacting DNA helicase 1 | Kartais (5–29%) | 1 ligoje |
| CASZ1castor zinc finger 1 | Kartais (5–29%) | 1 ligoje |
| CISD2CDGSH iron sulfur domain 2 | Kartais (5–29%) | 1 ligoje |
| CUL4Bcullin 4B | Kartais (5–29%) | 2 ligose |
| FAAP100FA core complex associated protein 100 | Kartais (5–29%) | 1 ligoje |
| FANCAFA complementation group A | Kartais (5–29%) | 1 ligoje |
| FANCCFA complementation group C | Kartais (5–29%) | 1 ligoje |
| FANCD2FA complementation group D2 | Kartais (5–29%) | 1 ligoje |
| FANCEFA complementation group E | Kartais (5–29%) | 1 ligoje |
| FANCFFA complementation group F | Kartais (5–29%) | 1 ligoje |
| FANCGFA complementation group G | Kartais (5–29%) | 1 ligoje |
| FANCIFA complementation group I | Kartais (5–29%) | 1 ligoje |
| FANCLFA complementation group L | Kartais (5–29%) | 1 ligoje |
| FANCMFA complementation group M | Kartais (5–29%) | 1 ligoje |
| GABRDgamma-aminobutyric acid type A receptor subunit delta | Kartais (5–29%) | 1 ligoje |
| HSPG2heparan sulfate proteoglycan 2 | Kartais (5–29%) | 1 ligoje |
| IER3IP1immediate early response 3 interacting protein 1 | Kartais (5–29%) | 1 ligoje |
| IFT54intraflagellar transport 54 | Kartais (5–29%) | 1 ligoje |
| KCNAB2potassium voltage-gated channel subfamily A regulatory beta subunit 2 | Kartais (5–29%) | 1 ligoje |
| LUZP1leucine zipper protein 1 | Kartais (5–29%) | 1 ligoje |
| MAD2L2mitotic arrest deficient 2 like 2 | Kartais (5–29%) | 1 ligoje |
| MAP2K1mitogen-activated protein kinase kinase 1 | Kartais (5–29%) | 1 ligoje |
| MMP23Bmatrix metallopeptidase 23B | Kartais (5–29%) | 1 ligoje |
| MT-ATP6mitochondrially encoded ATP synthase membrane subunit 6 | Kartais (5–29%) | 1 ligoje |
| MT-ATP8mitochondrially encoded ATP synthase membrane subunit 8 | Kartais (5–29%) | 1 ligoje |
| PALB2partner and localizer of BRCA2 | Kartais (5–29%) | 1 ligoje |
| PDE4Dphosphodiesterase 4D | Kartais (5–29%) | 1 ligoje |
| PDPNpodoplanin | Kartais (5–29%) | 1 ligoje |
| PHGDHphosphoglycerate dehydrogenase | Kartais (5–29%) | 1 ligoje |
| PRDM16PR/SET domain 16 | Kartais (5–29%) | 1 ligoje |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Kartais (5–29%) | 2 ligose |
| PRKCZprotein kinase C zeta | Kartais (5–29%) | 1 ligoje |
| PTDSS1phosphatidylserine synthase 1 | Kartais (5–29%) | 1 ligoje |
| PTPN11protein tyrosine phosphatase non-receptor type 11 | Kartais (5–29%) | 1 ligoje |
| RAD51RAD51 recombinase | Kartais (5–29%) | 1 ligoje |
| RAD51CRAD51 paralog C | Kartais (5–29%) | 1 ligoje |
| RELREL proto-oncogene, NF-kB subunit | Kartais (5–29%) | 1 ligoje |
| REREarginine-glutamic acid dipeptide repeats | Kartais (5–29%) | 1 ligoje |
| RFWD3ring finger and WD repeat domain 3 | Kartais (5–29%) | 1 ligoje |
| SKISKI proto-oncogene | Kartais (5–29%) | 1 ligoje |
| SLC29A3solute carrier family 29 member 3 | Kartais (5–29%) | 1 ligoje |
| SLX4SLX4 structure-specific endonuclease subunit | Kartais (5–29%) | 1 ligoje |
| SMAD4SMAD family member 4 | Kartais (5–29%) | 1 ligoje |
| SNAP29synaptosome associated protein 29 | Kartais (5–29%) | 1 ligoje |
| SPENspen family transcriptional repressor | Kartais (5–29%) | 1 ligoje |
| STSsteroid sulfatase | Kartais (5–29%) | 1 ligoje |
| STUB1STIP1 homology and U-box containing protein 1 | Kartais (5–29%) | 2 ligose |
| TGFB1transforming growth factor beta 1 | Kartais (5–29%) | 1 ligoje |
| TWNKtwinkle mtDNA helicase | Kartais (5–29%) | 1 ligoje |
| UBE2Tubiquitin conjugating enzyme E2 T | Kartais (5–29%) | 1 ligoje |
| UBE4Bubiquitination factor E4B | Kartais (5–29%) | 1 ligoje |
| VPS4Avacuolar protein sorting 4 homolog A | Kartais (5–29%) | 1 ligoje |
| WFS1wolframin ER transmembrane glycoprotein | Kartais (5–29%) | 1 ligoje |
| XPO1exportin 1 | Kartais (5–29%) | 1 ligoje |
| XRCC2X-ray repair cross complementing 2 | Kartais (5–29%) | 1 ligoje |
| DNM1Ldynamin 1L | Retai (1–4 %) | 1 ligoje |
| HBBhemoglobin subunit beta | Retai (1–4 %) | 1 ligoje |
| MYT1Lmyelin transcription factor 1 like | Retai (1–4 %) | 1 ligoje |
| OPA1OPA1 mitochondrial dynamin like GTPase | Retai (1–4 %) | 1 ligoje |
| PPIBpeptidylprolyl isomerase B | Retai (1–4 %) | 1 ligoje |
| ABCD1ATP binding cassette subfamily D member 1 | Neužfiksuota | 1 ligoje |
| ARandrogen receptor | Neužfiksuota | 1 ligoje |
| ARSLarylsulfatase L | Neužfiksuota | 1 ligoje |
| ATRXATRX chromatin remodeler | Neužfiksuota | 1 ligoje |
| CCDC28Bcoiled-coil domain containing 28B | Neužfiksuota | 1 ligoje |
| CNBPCCHC-type zinc finger nucleic acid binding protein | Neužfiksuota | 1 ligoje |
| DMPKDM1 protein kinase | Neužfiksuota | 1 ligoje |
| ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Neužfiksuota | 1 ligoje |
| FGF17fibroblast growth factor 17 | Neužfiksuota | 1 ligoje |
| FSHBfollicle stimulating hormone subunit beta | Neužfiksuota | 1 ligoje |
| GNASGNAS complex locus | Neužfiksuota | 2 ligose |
| HDAC8histone deacetylase 8 | Neužfiksuota | 1 ligoje |
| IL17RDinterleukin 17 receptor D | Neužfiksuota | 1 ligoje |
| LEPleptin | Neužfiksuota | 1 ligoje |
| PROP1PROP paired-like homeobox 1 | Neužfiksuota | 1 ligoje |
| RECQL4RecQ like helicase 4 | Neužfiksuota | 1 ligoje |
| SGPL1sphingosine-1-phosphate lyase 1 | Neužfiksuota | 1 ligoje |
| SLC39A4solute carrier family 39 member 4 | Neužfiksuota | 1 ligoje |
| TGFB2transforming growth factor beta 2 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
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- Duomenų leidimas 2026.10.17-8666dff2.
AtlasKam padedameMūsų mokslasProduktaiRezultatai
PrisijungtiKlaustiSekvenuokite savo genomą↗
Vienas testas. Atsakymai visam gyvenimui.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites