Požymis
Broad forehead
Width of the forehead or distance between the frontotemporales is more than two standard deviations above the mean (objective); or apparently increased distance between the two sides of the forehead.
Santrauka
- Taip pat vadinama
- Increased width of the forehead, Wide forehead, Bitemporal widening, Increased bitemporal dimension, Increased bitemporal width, Intertemporal widening
- Kūno sistema
- Abnormality of head or neck
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Broad forehead, and the rest of your genome, with one test.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites
Įsigyti savo Genome Test224 genų susiję su Broad forehead
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Broad forehead. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| ALDH18A1aldehyde dehydrogenase 18 family member A1 | Visada | 2 ligose |
| ALPK3alpha kinase 3 | Visada | 1 ligoje |
| AMOTL1angiomotin like 1 | Visada | 1 ligoje |
| ANKHANKH inorganic pyrophosphate transport regulator | Visada | 1 ligoje |
| ANTXR1ANTXR cell adhesion molecule 1 | Visada | 2 ligose |
| BUD13BUD13 spliceosome associated protein | Visada | 1 ligoje |
| CCDC22CCC complex scaffolding subunit CCDC22 | Visada | 1 ligoje |
| CHD8chromodomain helicase DNA binding protein 8 | Visada | 1 ligoje |
| DMRT2doublesex and mab-3 related transcription factor 2 | Visada | 1 ligoje |
| EMC10ER membrane protein complex subunit 10 | Visada | 1 ligoje |
| ESAMendothelial cell adhesion molecule | Visada | 1 ligoje |
| FBN1fibrillin 1 | Visada | 1 ligoje |
| IFIH1interferon induced with helicase C domain 1 | Visada | 1 ligoje |
| IGBP1immunoglobulin binding protein 1 | Visada | 1 ligoje |
| INPP4Ainositol polyphosphate-4-phosphatase type I A | Visada | 1 ligoje |
| JAG1jagged canonical Notch ligand 1 | Visada | 3 ligose |
| KDM6Blysine demethylase 6B | Visada | 1 ligoje |
| MKS1MKS transition zone complex subunit 1 | Visada | 2 ligose |
| NSD1nuclear receptor binding SET domain protein 1 | Visada | 2 ligose |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Visada | 1 ligoje |
| POLR1ARNA polymerase I subunit A | Visada | 1 ligoje |
| PSMD12proteasome 26S subunit, non-ATPase 12 | Visada | 1 ligoje |
| PTDSS1phosphatidylserine synthase 1 | Visada | 2 ligose |
| PYCR1pyrroline-5-carboxylate reductase 1 | Visada | 1 ligoje |
| RLIMring finger protein, LIM domain interacting | Visada | 1 ligoje |
| ROBO1roundabout guidance receptor 1 | Visada | 1 ligoje |
| SATB2SATB homeobox 2 | Visada | 1 ligoje |
| SHOC2SHOC2 leucine rich repeat scaffold protein | Visada | 1 ligoje |
| SKIC3SKI3 subunit of superkiller complex | Visada | 2 ligose |
| SLC25A24solute carrier family 25 member 24 | Visada | 2 ligose |
| TAFAZZINtafazzin, phospholipid-lysophospholipid transacylase | Visada | 2 ligose |
| TBC1D32TBC1 domain family member 32 | Visada | 1 ligoje |
| TBC1D7TBC1 domain family member 7 | Visada | 1 ligoje |
| TOMM7translocase of outer mitochondrial membrane 7 | Visada | 1 ligoje |
| UBAP2Lubiquitin associated protein 2 like | Visada | 1 ligoje |
| UNC13Aunc-13 homolog A | Visada | 1 ligoje |
| WASHC5WASH complex subunit 5 | Visada | 1 ligoje |
| YY1YY1 transcription factor | Visada | 2 ligose |
| AIPAHR interacting HSP90 co-chaperone | Labai dažnai (80–99%) | 1 ligoje |
| B4GALT7beta-1,4-galactosyltransferase 7 | Labai dažnai (80–99%) | 1 ligoje |
Rodyti dar 184 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| BAZ1Bbromodomain adjacent to zinc finger domain 1B | Labai dažnai (80–99%) | 1 ligoje |
| BUD23BUD23 rRNA methyltransferase and ribosome maturation factor | Labai dažnai (80–99%) | 1 ligoje |
| CAMTA1calmodulin binding transcription activator 1 | Labai dažnai (80–99%) | 1 ligoje |
| CCDC8coiled-coil domain containing 8 subunit of 3M complex | Labai dažnai (80–99%) | 1 ligoje |
| CITED2Cbp/p300 interacting transactivator with ED-rich tail 2 | Labai dažnai (80–99%) | 1 ligoje |
| CLIP2CAP-Gly domain containing linker protein 2 | Labai dažnai (80–99%) | 1 ligoje |
| CUL7cullin 7 | Labai dažnai (80–99%) | 1 ligoje |
| DNAJC30DnaJ heat shock protein family (Hsp40) member C30 | Labai dažnai (80–99%) | 1 ligoje |
| EIF4Heukaryotic translation initiation factor 4H | Labai dažnai (80–99%) | 1 ligoje |
| ELNelastin | Labai dažnai (80–99%) | 2 ligose |
| EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit | Labai dažnai (80–99%) | 1 ligoje |
| FGFR2fibroblast growth factor receptor 2 | Labai dažnai (80–99%) | 3 ligose |
| FGFR3fibroblast growth factor receptor 3 | Labai dažnai (80–99%) | 1 ligoje |
| FKBP6FKBP prolyl isomerase family member 6 (inactive) | Labai dažnai (80–99%) | 1 ligoje |
| FLNAfilamin A | Labai dažnai (80–99%) | 1 ligoje |
| FLT4fms related receptor tyrosine kinase 4 | Labai dažnai (80–99%) | 1 ligoje |
| GATA4GATA binding protein 4 | Labai dažnai (80–99%) | 2 ligose |
| GATA5GATA binding protein 5 | Labai dažnai (80–99%) | 1 ligoje |
| GATA6GATA binding protein 6 | Labai dažnai (80–99%) | 2 ligose |
| GDF1growth differentiation factor 1 | Labai dažnai (80–99%) | 1 ligoje |
| GJA5gap junction protein alpha 5 | Labai dažnai (80–99%) | 1 ligoje |
| GPC3glypican 3 | Labai dažnai (80–99%) | 1 ligoje |
| GPC4glypican 4 | Labai dažnai (80–99%) | 1 ligoje |
| GPR101G protein-coupled receptor 101 | Labai dažnai (80–99%) | 1 ligoje |
| GTF2Igeneral transcription factor IIi | Labai dažnai (80–99%) | 1 ligoje |
| GTF2IRD1GTF2I repeat domain containing 1 | Labai dažnai (80–99%) | 1 ligoje |
| GTF2IRD2GTF2I repeat domain containing 2 | Labai dažnai (80–99%) | 1 ligoje |
| KDRkinase insert domain receptor | Labai dažnai (80–99%) | 1 ligoje |
| LIMK1LIM domain kinase 1 | Labai dažnai (80–99%) | 1 ligoje |
| LRP5LDL receptor related protein 5 | Labai dažnai (80–99%) | 1 ligoje |
| MEF2Cmyocyte enhancer factor 2C | Labai dažnai (80–99%) | 2 ligose |
| METTL27methyltransferase like 27 | Labai dažnai (80–99%) | 1 ligoje |
| NCF1neutrophil cytosolic factor 1 | Labai dažnai (80–99%) | 1 ligoje |
| NKX2-5NK2 homeobox 5 | Labai dažnai (80–99%) | 2 ligose |
| NKX2-6NK2 homeobox 6 | Labai dažnai (80–99%) | 1 ligoje |
| OBSL1obscurin like cytoskeletal adaptor 1 | Labai dažnai (80–99%) | 1 ligoje |
| PIGNphosphatidylinositol glycan anchor biosynthesis class N | Labai dažnai (80–99%) | 1 ligoje |
| POLR3ARNA polymerase III subunit A | Labai dažnai (80–99%) | 1 ligoje |
| RAI1retinoic acid induced 1 | Labai dažnai (80–99%) | 3 ligose |
| RFC2replication factor C subunit 2 | Labai dažnai (80–99%) | 1 ligoje |
| RNF135ring finger protein 135 | Labai dažnai (80–99%) | 1 ligoje |
| SETBP1SET binding protein 1 | Labai dažnai (80–99%) | 1 ligoje |
| STX1Asyntaxin 1A | Labai dažnai (80–99%) | 1 ligoje |
| SUZ12SUZ12 polycomb repressive complex 2 subunit | Labai dažnai (80–99%) | 1 ligoje |
| TBL2transducin beta like 2 | Labai dažnai (80–99%) | 1 ligoje |
| TBX1T-box transcription factor 1 | Labai dažnai (80–99%) | 2 ligose |
| TCF12transcription factor 12 | Labai dažnai (80–99%) | 1 ligoje |
| TMEM270transmembrane protein 270 | Labai dažnai (80–99%) | 1 ligoje |
| TWIST1twist family bHLH transcription factor 1 | Labai dažnai (80–99%) | 1 ligoje |
| VPS37DVPS37D subunit of ESCRT-I | Labai dažnai (80–99%) | 1 ligoje |
| ZBTB20zinc finger and BTB domain containing 20 | Labai dažnai (80–99%) | 1 ligoje |
| ZFPM2zinc finger protein, FOG family member 2 | Labai dažnai (80–99%) | 2 ligose |
| ZIC1Zic family zinc finger 1 | Labai dažnai (80–99%) | 1 ligoje |
| ACTL6Bactin like 6B | Dažnai (30–79%) | 1 ligoje |
| ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3 | Dažnai (30–79%) | 1 ligoje |
| AHDC1AT-hook DNA binding motif containing 1 | Dažnai (30–79%) | 1 ligoje |
| B3GAT3beta-1,3-glucuronyltransferase 3 | Dažnai (30–79%) | 1 ligoje |
| BMP1bone morphogenetic protein 1 | Dažnai (30–79%) | 1 ligoje |
| BMP2bone morphogenetic protein 2 | Dažnai (30–79%) | 1 ligoje |
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Dažnai (30–79%) | 1 ligoje |
| CASKcalcium/calmodulin dependent serine protein kinase | Dažnai (30–79%) | 1 ligoje |
| CBLCbl proto-oncogene | Dažnai (30–79%) | 1 ligoje |
| CCBE1collagen and calcium binding EGF domains 1 | Dažnai (30–79%) | 2 ligose |
| CDH11cadherin 11 | Dažnai (30–79%) | 1 ligoje |
| CDKL5cyclin dependent kinase like 5 | Dažnai (30–79%) | 2 ligose |
| CHST3carbohydrate sulfotransferase 3 | Dažnai (30–79%) | 3 ligose |
| CKAP2Lcytoskeleton associated protein 2L | Dažnai (30–79%) | 2 ligose |
| DPH5diphthamide biosynthesis 5 | Dažnai (30–79%) | 1 ligoje |
| FAT4FAT atypical cadherin 4 | Dažnai (30–79%) | 1 ligoje |
| FGD1FYVE, RhoGEF and PH domain containing 1 | Dažnai (30–79%) | 1 ligoje |
| FUT8fucosyltransferase 8 | Dažnai (30–79%) | 1 ligoje |
| GATAD2BGATA zinc finger domain containing 2B | Dažnai (30–79%) | 2 ligose |
| HBA1hemoglobin subunit alpha 1 | Dažnai (30–79%) | 1 ligoje |
| HBA2hemoglobin subunit alpha 2 | Dažnai (30–79%) | 1 ligoje |
| HOXB1homeobox B1 | Dažnai (30–79%) | 1 ligoje |
| KANSL1KAT8 regulatory NSL complex subunit 1 | Dažnai (30–79%) | 1 ligoje |
| KIF7kinesin family member 7 | Dažnai (30–79%) | 1 ligoje |
| LRP2LDL receptor related protein 2 | Dažnai (30–79%) | 1 ligoje |
| MAP2K1mitogen-activated protein kinase kinase 1 | Dažnai (30–79%) | 1 ligoje |
| MBD5methyl-CpG binding domain protein 5 | Dažnai (30–79%) | 2 ligose |
| NFIXnuclear factor I X | Dažnai (30–79%) | 1 ligoje |
| NRASNRAS proto-oncogene, GTPase | Dažnai (30–79%) | 2 ligose |
| PAN2poly(A) specific ribonuclease subunit PAN2 | Dažnai (30–79%) | 1 ligoje |
| POGZpogo transposable element derived with ZNF domain | Dažnai (30–79%) | 1 ligoje |
| POLEDNA polymerase epsilon, catalytic subunit | Dažnai (30–79%) | 1 ligoje |
| PPM1Dprotein phosphatase, Mg2+/Mn2+ dependent 1D | Dažnai (30–79%) | 1 ligoje |
| PRIM1DNA primase subunit 1 | Dažnai (30–79%) | 1 ligoje |
| PTBP1polypyrimidine tract binding protein 1 | Dažnai (30–79%) | 1 ligoje |
| PTPN11protein tyrosine phosphatase non-receptor type 11 | Dažnai (30–79%) | 1 ligoje |
| RBM8ARNA binding motif protein 8A | Dažnai (30–79%) | 1 ligoje |
| RYR3ryanodine receptor 3 | Dažnai (30–79%) | 1 ligoje |
| SH3PXD2BSH3 and PX domains 2B | Dažnai (30–79%) | 1 ligoje |
| SIN3ASIN3 transcription regulator family member A | Dažnai (30–79%) | 1 ligoje |
| SKIC2SKI2 subunit of superkiller complex | Dažnai (30–79%) | 1 ligoje |
| SMAD2SMAD family member 2 | Dažnai (30–79%) | 1 ligoje |
| STEEP1STING1 ER exit protein 1 | Dažnai (30–79%) | 1 ligoje |
| TCEAL1transcription elongation factor A like 1 | Dažnai (30–79%) | 1 ligoje |
| TRPM3transient receptor potential cation channel subfamily M member 3 | Dažnai (30–79%) | 1 ligoje |
| ZRSR2zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2 | Dažnai (30–79%) | 1 ligoje |
| ACTG2actin gamma 2, smooth muscle | Kartais (5–29%) | 1 ligoje |
| CDC42BPBCDC42 binding protein kinase beta | Kartais (5–29%) | 1 ligoje |
| CDH2cadherin 2 | Kartais (5–29%) | 1 ligoje |
| CUX1cut like homeobox 1 | Kartais (5–29%) | 1 ligoje |
| DLK1delta like non-canonical Notch ligand 1 | Kartais (5–29%) | 1 ligoje |
| DLL3delta like canonical Notch ligand 3 | Kartais (5–29%) | 1 ligoje |
| DPP9dipeptidyl peptidase 9 | Kartais (5–29%) | 1 ligoje |
| EBF3EBF transcription factor 3 | Kartais (5–29%) | 2 ligose |
| FBLN5fibulin 5 | Kartais (5–29%) | 1 ligoje |
| FBXO11F-box protein 11 | Kartais (5–29%) | 1 ligoje |
| HECTD4HECT domain E3 ubiquitin protein ligase 4 | Kartais (5–29%) | 1 ligoje |
| HES7hes family bHLH transcription factor 7 | Kartais (5–29%) | 1 ligoje |
| HIVEP2HIVEP zinc finger 2 | Kartais (5–29%) | 1 ligoje |
| IDH1isocitrate dehydrogenase (NADP(+)) 1 | Kartais (5–29%) | 1 ligoje |
| JARID2jumonji and AT-rich interaction domain containing 2 | Kartais (5–29%) | 1 ligoje |
| KCNH1potassium voltage-gated channel subfamily H member 1 | Kartais (5–29%) | 1 ligoje |
| KCNJ2potassium inwardly rectifying channel subfamily J member 2 | Kartais (5–29%) | 2 ligose |
| KCNJ5potassium inwardly rectifying channel subfamily J member 5 | Kartais (5–29%) | 1 ligoje |
| KDM2Blysine demethylase 2B | Kartais (5–29%) | 1 ligoje |
| LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | Kartais (5–29%) | 1 ligoje |
| MADDMAP kinase activating death domain | Kartais (5–29%) | 1 ligoje |
| MAN2B1mannosidase alpha class 2B member 1 | Kartais (5–29%) | 2 ligose |
| MARK2microtubule affinity regulating kinase 2 | Kartais (5–29%) | 1 ligoje |
| MED13Lmediator complex subunit 13L | Kartais (5–29%) | 1 ligoje |
| MEG3maternally expressed 3 | Kartais (5–29%) | 1 ligoje |
| MESP2mesoderm posterior bHLH transcription factor 2 | Kartais (5–29%) | 1 ligoje |
| NAA10N-alpha-acetyltransferase 10, NatA catalytic subunit | Kartais (5–29%) | 1 ligoje |
| NALCNsodium leak channel, non-selective | Kartais (5–29%) | 1 ligoje |
| NARS1asparaginyl-tRNA synthetase 1 | Kartais (5–29%) | 1 ligoje |
| NF1neurofibromin 1 | Kartais (5–29%) | 1 ligoje |
| NIPA1NIPA magnesium transporter 1 | Kartais (5–29%) | 1 ligoje |
| NIPA2NIPA magnesium transporter 2 | Kartais (5–29%) | 1 ligoje |
| ODC1ornithine decarboxylase 1 | Kartais (5–29%) | 1 ligoje |
| PIGUphosphatidylinositol glycan anchor biosynthesis class U | Kartais (5–29%) | 1 ligoje |
| PPP2CAprotein phosphatase 2 catalytic subunit alpha | Kartais (5–29%) | 1 ligoje |
| PRKACBprotein kinase cAMP-activated catalytic subunit beta | Kartais (5–29%) | 1 ligoje |
| PSPHphosphoserine phosphatase | Kartais (5–29%) | 1 ligoje |
| RAB34RAB34, member RAS oncogene family | Kartais (5–29%) | 1 ligoje |
| RECQL4RecQ like helicase 4 | Kartais (5–29%) | 1 ligoje |
| RIPPLY2ripply transcriptional repressor 2 | Kartais (5–29%) | 1 ligoje |
| RPL10ribosomal protein L10 | Kartais (5–29%) | 1 ligoje |
| RTL1retrotransposon Gag like 1 | Kartais (5–29%) | 1 ligoje |
| RUNX2RUNX family transcription factor 2 | Kartais (5–29%) | 1 ligoje |
| SCNM1sodium channel modifier 1 | Kartais (5–29%) | 1 ligoje |
| SH2B1SH2B adaptor protein 1 | Kartais (5–29%) | 1 ligoje |
| SIM1SIM bHLH transcription factor 1 | Kartais (5–29%) | 1 ligoje |
| SLC26A2solute carrier family 26 member 2 | Kartais (5–29%) | 1 ligoje |
| TBCBtubulin folding cofactor B | Kartais (5–29%) | 1 ligoje |
| TBCKTBC1 domain containing kinase | Kartais (5–29%) | 2 ligose |
| TBX6T-box transcription factor 6 | Kartais (5–29%) | 1 ligoje |
| TCTN2tectonic family member 2 | Kartais (5–29%) | 1 ligoje |
| THOC2THO complex subunit 2 | Kartais (5–29%) | 1 ligoje |
| THOC6THO complex subunit 6 | Kartais (5–29%) | 1 ligoje |
| TTC5tetratricopeptide repeat domain 5 | Kartais (5–29%) | 1 ligoje |
| TUBG1tubulin gamma 1 | Kartais (5–29%) | 1 ligoje |
| WACWW domain containing adaptor with coiled-coil | Kartais (5–29%) | 2 ligose |
| WBP11WW domain binding protein 11 | Kartais (5–29%) | 1 ligoje |
| WDR83OSWD repeat domain 83 opposite strand | Kartais (5–29%) | 1 ligoje |
| ZFXzinc finger protein X-linked | Kartais (5–29%) | 1 ligoje |
| ZIC2Zic family zinc finger 2 | Kartais (5–29%) | 1 ligoje |
| CNTNAP2contactin associated protein 2 | Retai (1–4 %) | 1 ligoje |
| SPTBN1spectrin beta, non-erythrocytic 1 | Retai (1–4 %) | 1 ligoje |
| ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase | Neužfiksuota | 1 ligoje |
| AMMECR1AMMECR nuclear protein 1 | Neužfiksuota | 1 ligoje |
| CCNQcyclin Q | Neužfiksuota | 1 ligoje |
| CHST14carbohydrate sulfotransferase 14 | Neužfiksuota | 1 ligoje |
| COLEC11collectin subfamily member 11 | Neužfiksuota | 1 ligoje |
| DNMT3ADNA methyltransferase 3 alpha | Neužfiksuota | 1 ligoje |
| EEDembryonic ectoderm development | Neužfiksuota | 1 ligoje |
| FLCNfolliculin | Neužfiksuota | 1 ligoje |
| HRASHRas proto-oncogene, GTPase | Neužfiksuota | 1 ligoje |
| KRASKRas proto-oncogene, GTPase | Neužfiksuota | 1 ligoje |
| NFIAnuclear factor I A | Neužfiksuota | 1 ligoje |
| NOTCH2notch receptor 2 | Neužfiksuota | 1 ligoje |
| PAK1p21 (RAC1) activated kinase 1 | Neužfiksuota | 1 ligoje |
| PCGF2polycomb group ring finger 2 | Neužfiksuota | 1 ligoje |
| PEX3peroxisomal biogenesis factor 3 | Neužfiksuota | 1 ligoje |
| PIGBphosphatidylinositol glycan anchor biosynthesis class B | Neužfiksuota | 1 ligoje |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Neužfiksuota | 1 ligoje |
| PTENphosphatase and tensin homolog | Neužfiksuota | 1 ligoje |
| SLC6A8solute carrier family 6 member 8 | Neužfiksuota | 1 ligoje |
| TENT5Aterminal nucleotidyltransferase 5A | Neužfiksuota | 1 ligoje |
| TET3tet methylcytosine dioxygenase 3 | Neužfiksuota | 1 ligoje |
| TFAP2Btranscription factor AP-2 beta | Neužfiksuota | 1 ligoje |
| UNC80unc-80 subunit of NALCN channel complex | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
Platesni požymiai
Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
Vienas testas. Atsakymai visam gyvenimui.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites