Tunnus
Bleeding tendency
Kliiniline nimetus: Abnormal bleeding
An abnormal susceptibility to bleeding, often referred to as a bleeding diathesis. A bleeding diathesis may be related to vascular, platelet and coagulation defects.
Kokkuvõte
- Teised nimetused
- Bleeding diathesis, Hemorrhagic diathesis
VõrdlusgenoomGRCh38hg38
Geeni- ja variandilehtede positsioonid järgivad seda valikut selles brauseris.
Read the genes linked to Bleeding tendency, and the rest of your genome, with one test.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast
Telli oma Genome Test140 geeni on seotud tunnusega Bleeding tendency
Nende geenide muutused põhjustavad haruldasi haigusi, mille puhul esineb Bleeding tendency. Enamikul selle tunnusega inimestest ei ole ühtegi neist haigustest. Selles loendis olev geen ei ütle midagi kellegi enda genoomi kohta.
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| ALG13ALG13 UDP-N-acetylglucosaminyltransferase subunit | Alati | Esineb 1 haiguses |
| F13A1coagulation factor XIII A chain | Alati | Esineb 1 haiguses |
| F13Bcoagulation factor XIII B chain | Alati | Esineb 1 haiguses |
| FGAfibrinogen alpha chain | Alati | Esineb 4 haiguses |
| FGBfibrinogen beta chain | Alati | Esineb 4 haiguses |
| FGGfibrinogen gamma chain | Alati | Esineb 4 haiguses |
| FYB1FYN binding protein 1 | Alati | Esineb 1 haiguses |
| GALEUDP-galactose-4-epimerase | Alati | Esineb 1 haiguses |
| GFI1Bgrowth factor independent 1B transcriptional repressor | Alati | Esineb 1 haiguses |
| HPS3HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 | Alati | Esineb 1 haiguses |
| HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 | Alati | Esineb 1 haiguses |
| ITGB3integrin subunit beta 3 | Alati | Esineb 3 haiguses |
| PRKACGprotein kinase cAMP-activated catalytic subunit gamma | Alati | Esineb 1 haiguses |
| PTPRJprotein tyrosine phosphatase receptor type J | Alati | Esineb 1 haiguses |
| ARF1ARF GTPase 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| ARFGEF2ARF guanine nucleotide exchange factor 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| BMPR1Abone morphogenetic protein receptor type 1A | Väga sageli (80–99%) | Esineb 3 haiguses |
| CHST14carbohydrate sulfotransferase 14 | Väga sageli (80–99%) | Esineb 1 haiguses |
| DSEdermatan sulfate epimerase | Väga sageli (80–99%) | Esineb 1 haiguses |
| ENGendoglin | Väga sageli (80–99%) | Esineb 1 haiguses |
| ERMARDER membrane associated RNA degradation | Väga sageli (80–99%) | Esineb 1 haiguses |
| F11coagulation factor XI | Väga sageli (80–99%) | Esineb 2 haiguses |
| F8coagulation factor VIII | Väga sageli (80–99%) | Esineb 2 haiguses |
| FLNAfilamin A | Väga sageli (80–99%) | Esineb 1 haiguses |
| GATA1GATA binding protein 1 | Väga sageli (80–99%) | Esineb 2 haiguses |
| GP1BAglycoprotein Ib platelet subunit alpha | Väga sageli (80–99%) | Esineb 3 haiguses |
| GP1BBglycoprotein Ib platelet subunit beta | Väga sageli (80–99%) | Esineb 3 haiguses |
| GP9glycoprotein IX platelet | Väga sageli (80–99%) | Esineb 2 haiguses |
| GREM1gremlin 1, DAN family BMP antagonist | Väga sageli (80–99%) | Esineb 1 haiguses |
| JAK2Janus kinase 2 | Väga sageli (80–99%) | Esineb 3 haiguses |
| MAP1Bmicrotubule associated protein 1B | Väga sageli (80–99%) | Esineb 1 haiguses |
| MPLMPL proto-oncogene, thrombopoietin receptor | Väga sageli (80–99%) | Esineb 3 haiguses |
| NBEAL2neurobeachin like 2 | Väga sageli (80–99%) | Esineb 2 haiguses |
| NEDD4LNEDD4 like E3 ubiquitin protein ligase | Väga sageli (80–99%) | Esineb 1 haiguses |
| SLC35A1solute carrier family 35 member A1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| SMAD4SMAD family member 4 | Väga sageli (80–99%) | Esineb 1 haiguses |
| THPOthrombopoietin | Väga sageli (80–99%) | Esineb 2 haiguses |
| TMTC3transmembrane O-mannosyltransferase targeting cadherins 3 | Väga sageli (80–99%) | Esineb 1 haiguses |
| ATRXATRX chromatin remodeler | Sageli (30–79%) | Esineb 1 haiguses |
| BCORBCL6 corepressor | Sageli (30–79%) | Esineb 1 haiguses |
Näita veel 100 geeni
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| BRAFB-Raf proto-oncogene, serine/threonine kinase | Sageli (30–79%) | Esineb 2 haiguses |
| CALRcalreticulin | Sageli (30–79%) | Esineb 2 haiguses |
| CASP10caspase 10 | Sageli (30–79%) | Esineb 1 haiguses |
| CBLCbl proto-oncogene | Sageli (30–79%) | Esineb 1 haiguses |
| CD109CD109 molecule | Sageli (30–79%) | Esineb 1 haiguses |
| F2coagulation factor II, thrombin | Sageli (30–79%) | Esineb 1 haiguses |
| FASFas cell surface death receptor | Sageli (30–79%) | Esineb 1 haiguses |
| FASLGFas ligand | Sageli (30–79%) | Esineb 1 haiguses |
| FIP1L1factor interacting with PAPOLA and CPSF1 | Sageli (30–79%) | Esineb 1 haiguses |
| FLI1Fli-1 proto-oncogene, ETS transcription factor | Sageli (30–79%) | Esineb 2 haiguses |
| GGCXgamma-glutamyl carboxylase | Sageli (30–79%) | Esineb 4 haiguses |
| IRF2BP2interferon regulatory factor 2 binding protein 2 | Sageli (30–79%) | Esineb 1 haiguses |
| ITGA2integrin subunit alpha 2 | Sageli (30–79%) | Esineb 1 haiguses |
| ITGA2Bintegrin subunit alpha 2b | Sageli (30–79%) | Esineb 2 haiguses |
| KRASKRas proto-oncogene, GTPase | Sageli (30–79%) | Esineb 1 haiguses |
| LYSTlysosomal trafficking regulator | Sageli (30–79%) | Esineb 1 haiguses |
| LZTR1leucine zipper like post translational regulator 1 | Sageli (30–79%) | Esineb 1 haiguses |
| MRASmuscle RAS oncogene homolog | Sageli (30–79%) | Esineb 1 haiguses |
| NABP1nucleic acid binding protein 1 | Sageli (30–79%) | Esineb 1 haiguses |
| NPM1nucleophosmin 1 | Sageli (30–79%) | Esineb 1 haiguses |
| NRASNRAS proto-oncogene, GTPase | Sageli (30–79%) | Esineb 1 haiguses |
| NUMA1nuclear mitotic apparatus protein 1 | Sageli (30–79%) | Esineb 1 haiguses |
| PMLPML nuclear body scaffold | Sageli (30–79%) | Esineb 1 haiguses |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Sageli (30–79%) | Esineb 1 haiguses |
| PTENphosphatase and tensin homolog | Sageli (30–79%) | Esineb 1 haiguses |
| PTPN11protein tyrosine phosphatase non-receptor type 11 | Sageli (30–79%) | Esineb 2 haiguses |
| RAF1Raf-1 proto-oncogene, serine/threonine kinase | Sageli (30–79%) | Esineb 1 haiguses |
| RARAretinoic acid receptor alpha | Sageli (30–79%) | Esineb 1 haiguses |
| RASA2RAS p21 protein activator 2 | Sageli (30–79%) | Esineb 1 haiguses |
| RFT1RFT1 glycolipid translocator homolog | Sageli (30–79%) | Esineb 1 haiguses |
| RIT1Ras like without CAAX 1 | Sageli (30–79%) | Esineb 1 haiguses |
| RRASRAS related | Sageli (30–79%) | Esineb 1 haiguses |
| RRAS2RAS related 2 | Sageli (30–79%) | Esineb 1 haiguses |
| SERPINF2serpin family F member 2 | Sageli (30–79%) | Esineb 1 haiguses |
| SH2B3SH2B adaptor protein 3 | Sageli (30–79%) | Esineb 1 haiguses |
| SLC7A7solute carrier family 7 member 7 | Sageli (30–79%) | Esineb 1 haiguses |
| SOS1SOS Ras/Rac guanine nucleotide exchange factor 1 | Sageli (30–79%) | Esineb 2 haiguses |
| SOS2SOS Ras/Rho guanine nucleotide exchange factor 2 | Sageli (30–79%) | Esineb 1 haiguses |
| SPRED2sprouty related EVH1 domain containing 2 | Sageli (30–79%) | Esineb 1 haiguses |
| STAT3signal transducer and activator of transcription 3 | Sageli (30–79%) | Esineb 1 haiguses |
| STAT5Bsignal transducer and activator of transcription 5B | Sageli (30–79%) | Esineb 1 haiguses |
| TBL1XR1TBL1X/Y related 1 | Sageli (30–79%) | Esineb 1 haiguses |
| TET2tet methylcytosine dioxygenase 2 | Sageli (30–79%) | Esineb 4 haiguses |
| TP53tumor protein p53 | Sageli (30–79%) | Esineb 1 haiguses |
| VKORC1vitamin K epoxide reductase complex subunit 1 | Sageli (30–79%) | Esineb 2 haiguses |
| ZBTB16zinc finger and BTB domain containing 16 | Sageli (30–79%) | Esineb 1 haiguses |
| ALKALK receptor tyrosine kinase | Mõnikord (5–29%) | Esineb 1 haiguses |
| AMNamnion associated transmembrane protein | Mõnikord (5–29%) | Esineb 1 haiguses |
| B4GALT1beta-1,4-galactosyltransferase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| CLPBClpB family mitochondrial disaggregase | Mõnikord (5–29%) | Esineb 1 haiguses |
| COG6component of oligomeric golgi complex 6 | Mõnikord (5–29%) | Esineb 1 haiguses |
| CUBNcubilin | Mõnikord (5–29%) | Esineb 1 haiguses |
| EPORerythropoietin receptor | Mõnikord (5–29%) | Esineb 1 haiguses |
| GBA1glucosylceramidase beta 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| HSD3B7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | Mõnikord (5–29%) | Esineb 1 haiguses |
| IPO8importin 8 | Mõnikord (5–29%) | Esineb 1 haiguses |
| LIN28Blin-28 RNA binding posttranscriptional regulator B | Mõnikord (5–29%) | Esineb 1 haiguses |
| LMO1LIM domain only 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MAP2K1mitogen-activated protein kinase kinase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MGAT2alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | Mõnikord (5–29%) | Esineb 1 haiguses |
| MYCNMYCN proto-oncogene, bHLH transcription factor | Mõnikord (5–29%) | Esineb 1 haiguses |
| PHOX2Bpaired like homeobox 2B | Mõnikord (5–29%) | Esineb 1 haiguses |
| PLOD1procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| RASA1RAS p21 protein activator 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| RPS14ribosomal protein S14 | Mõnikord (5–29%) | Esineb 1 haiguses |
| RYR1ryanodine receptor 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SCARB2scavenger receptor class B member 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SLC37A4solute carrier family 37 member 4 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SMAD2SMAD family member 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SMAD3SMAD family member 3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TGFB2transforming growth factor beta 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TGFB3transforming growth factor beta 3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TGFBR1transforming growth factor beta receptor 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TGFBR2transforming growth factor beta receptor 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| URODuroporphyrinogen decarboxylase | Mõnikord (5–29%) | Esineb 1 haiguses |
| UROSuroporphyrinogen III synthase | Mõnikord (5–29%) | Esineb 1 haiguses |
| VPS33BVPS33B late endosome and lysosome associated | Mõnikord (5–29%) | Esineb 1 haiguses |
| F12coagulation factor XII | Harva (1–4%) | Esineb 1 haiguses |
| MTTPmicrosomal triglyceride transfer protein | Harva (1–4%) | Esineb 1 haiguses |
| SF3B1splicing factor 3b subunit 1 | Harva (1–4%) | Esineb 1 haiguses |
| SLC25A13solute carrier family 25 member 13 | Harva (1–4%) | Esineb 1 haiguses |
| SMPD1sphingomyelin phosphodiesterase 1 | Harva (1–4%) | Esineb 1 haiguses |
| ABCG8ATP binding cassette subfamily G member 8 | Pole registreeritud | Esineb 1 haiguses |
| ANO6anoctamin 6 | Pole registreeritud | Esineb 1 haiguses |
| CD36CD36 molecule (CD36 blood group) | Pole registreeritud | Esineb 1 haiguses |
| CISD2CDGSH iron sulfur domain 2 | Pole registreeritud | Esineb 1 haiguses |
| F5coagulation factor V | Pole registreeritud | Esineb 1 haiguses |
| F7coagulation factor VII | Pole registreeritud | Esineb 1 haiguses |
| FERMT3FERM domain containing kindlin 3 | Pole registreeritud | Esineb 1 haiguses |
| G6PC1glucose-6-phosphatase catalytic subunit 1 | Pole registreeritud | Esineb 1 haiguses |
| LMAN1lectin, mannose binding 1 | Pole registreeritud | Esineb 1 haiguses |
| MPImannose phosphate isomerase | Pole registreeritud | Esineb 1 haiguses |
| MYH9myosin heavy chain 9 | Pole registreeritud | Esineb 1 haiguses |
| P2RY12purinergic receptor P2Y12 | Pole registreeritud | Esineb 1 haiguses |
| PEX12peroxisomal biogenesis factor 12 | Pole registreeritud | Esineb 1 haiguses |
| SERPINE1serpin family E member 1 | Pole registreeritud | Esineb 1 haiguses |
| SRCSRC proto-oncogene, non-receptor tyrosine kinase | Pole registreeritud | Esineb 1 haiguses |
| STIM1stromal interaction molecule 1 | Pole registreeritud | Esineb 1 haiguses |
| VWFvon Willebrand factor | Pole registreeritud | Esineb 1 haiguses |
Kui sageli see esineb geenist tulenevate seisunditega inimeste seas, kõige sagedamini nende kõigi seas, nagu on märgitud Inimese fenotüübi ontoloogias. Need lehed kirjeldavad tunnuseid ja nende taga olevaid uuringuid; need ei ole diagnoos ning sümptomite kohta tuleks küsida arstilt või geneetilt nõustajalt.
Kitsamad tunnused
- Bloody nose110 geeni
- Bleeding gums61 geeni
- Prolonged bleeding time48 geeni
- Abnormally heavy bleeding during menstruation43 geeni
- Oral cavity bleeding22 geeni
- Bleeding below the skin15 geeni
- Excessive bleeding after minor trauma15 geeni
- Cephalohematoma13 geeni
- Internal bleeding11 geeni
- Abnormal umbilical stump bleeding10 geeni
- Bleeding with minor or no trauma8 geeni
- Prolonged bleeding following procedure7 geeni
- Excessive bleeding from superficial cuts5 geeni
- Abnormal vaginal bleeding2 geeni
- Bleeding requiring red cell transfusion1 geen
- Excessive bleeding after a venipuncture1 geen
- Abnormal onset of bleeding
Laiemad tunnused
Allikas
- Inimese fenotüübi ontoloogia, versioon 2026-09-01: tunnus, selle nimetused, määratlus ja sellega seotud geenid. Lisateave leiab aadressilt hpo.jax.org.
- Andmeversioon 2026.10.16-c6eea6bf.
Üks test. Vastused kogu eluks.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast