Požymis
Joint stiffness
Joint stiffness is a perceived sensation of tightness in a joint or joints when attempting to move them after a period of inactivity. Joint stiffness typically subsides over time.
Santrauka
- Taip pat vadinama
- Stiff joint, Stiff joints
- Kūno sistema
- Abnormality of the musculoskeletal system
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
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Įsigyti savo Genome Test187 genų susiję su Joint stiffness
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Joint stiffness. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| ADAMTS10ADAM metallopeptidase with thrombospondin type 1 motif 10 | Visada | 2 ligose |
| ADAMTSL2ADAMTS like 2 | Visada | 1 ligoje |
| BANF1barrier to autointegration nuclear assembly factor 1 | Visada | 1 ligoje |
| COL2A1collagen type II alpha 1 chain | Visada | 4 ligose |
| GLB1galactosidase beta 1 | Visada | 3 ligose |
| GNPTGN-acetylglucosamine-1-phosphate transferase subunit gamma | Visada | 1 ligoje |
| IDUAalpha-L-iduronidase | Visada | 3 ligose |
| KRT83keratin 83 | Visada | 1 ligoje |
| LMNAlamin A/C | Visada | 4 ligose |
| SMAD4SMAD family member 4 | Visada | 2 ligose |
| UBAP2Lubiquitin associated protein 2 like | Visada | 1 ligoje |
| ADAMTSL4ADAMTS like 4 | Labai dažnai (80–99%) | 1 ligoje |
| ANTXR2ANTXR cell adhesion molecule 2 | Labai dažnai (80–99%) | 2 ligose |
| ATAD1ATPase family AAA domain containing 1 | Labai dažnai (80–99%) | 1 ligoje |
| BMPR1Bbone morphogenetic protein receptor type 1B | Labai dažnai (80–99%) | 1 ligoje |
| EMDemerin | Labai dažnai (80–99%) | 1 ligoje |
| EMG1EMG1 N1-specific pseudouridine methyltransferase | Labai dažnai (80–99%) | 1 ligoje |
| ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit | Labai dažnai (80–99%) | 1 ligoje |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Labai dažnai (80–99%) | 1 ligoje |
| ERCC5ERCC excision repair 5, endonuclease | Labai dažnai (80–99%) | 1 ligoje |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Labai dažnai (80–99%) | 1 ligoje |
| FBN1fibrillin 1 | Labai dažnai (80–99%) | 6 ligose |
| FBN2fibrillin 2 | Labai dažnai (80–99%) | 1 ligoje |
| FGF9fibroblast growth factor 9 | Labai dažnai (80–99%) | 1 ligoje |
| FHL1four and a half LIM domains 1 | Labai dažnai (80–99%) | 1 ligoje |
| FKBP10FKBP prolyl isomerase 10 | Labai dažnai (80–99%) | 2 ligose |
| GDF5growth differentiation factor 5 | Labai dažnai (80–99%) | 3 ligose |
| GDF6growth differentiation factor 6 | Labai dažnai (80–99%) | 1 ligoje |
| GLRA1glycine receptor alpha 1 | Labai dažnai (80–99%) | 1 ligoje |
| GLRBglycine receptor beta | Labai dažnai (80–99%) | 1 ligoje |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Labai dažnai (80–99%) | 1 ligoje |
| GPHNgephyrin | Labai dažnai (80–99%) | 1 ligoje |
| HGDhomogentisate 1,2-dioxygenase | Labai dažnai (80–99%) | 1 ligoje |
| HLA-Bmajor histocompatibility complex, class I, B | Labai dažnai (80–99%) | 2 ligose |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Labai dažnai (80–99%) | 1 ligoje |
| HSPG2heparan sulfate proteoglycan 2 | Labai dažnai (80–99%) | 2 ligose |
| IRF6interferon regulatory factor 6 | Labai dažnai (80–99%) | 1 ligoje |
| LSSlanosterol synthase | Labai dažnai (80–99%) | 1 ligoje |
| MACROH2A1macroH2A.1 histone | Labai dažnai (80–99%) | 1 ligoje |
| MFN2mitofusin 2 | Labai dažnai (80–99%) | 1 ligoje |
Rodyti dar 147 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| MMP13matrix metallopeptidase 13 | Labai dažnai (80–99%) | 1 ligoje |
| MMP9matrix metallopeptidase 9 | Labai dažnai (80–99%) | 1 ligoje |
| MYH3myosin heavy chain 3 | Labai dažnai (80–99%) | 3 ligose |
| NALCNsodium leak channel, non-selective | Labai dažnai (80–99%) | 3 ligose |
| NOGnoggin | Labai dažnai (80–99%) | 1 ligoje |
| P4HA2prolyl 4-hydroxylase subunit alpha 2 | Labai dažnai (80–99%) | 1 ligoje |
| PAX3paired box 3 | Labai dažnai (80–99%) | 1 ligoje |
| PIEZO2piezo type mechanosensitive ion channel component 2 | Labai dažnai (80–99%) | 2 ligose |
| PITX1paired like homeodomain 1 | Labai dažnai (80–99%) | 1 ligoje |
| PLOD2procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 | Labai dažnai (80–99%) | 1 ligoje |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Labai dažnai (80–99%) | 2 ligose |
| RAB18RAB18, member RAS oncogene family | Labai dažnai (80–99%) | 1 ligoje |
| RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1 | Labai dažnai (80–99%) | 1 ligoje |
| RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2 | Labai dažnai (80–99%) | 1 ligoje |
| SALL4spalt like transcription factor 4 | Labai dažnai (80–99%) | 1 ligoje |
| SHOXSHOX homeobox | Labai dažnai (80–99%) | 1 ligoje |
| SLC6A5solute carrier family 6 member 5 | Labai dažnai (80–99%) | 1 ligoje |
| SYNE1spectrin repeat containing nuclear envelope protein 1 | Labai dažnai (80–99%) | 1 ligoje |
| SYNE2spectrin repeat containing nuclear envelope protein 2 | Labai dažnai (80–99%) | 1 ligoje |
| TBC1D20TBC1 domain family member 20 | Labai dažnai (80–99%) | 1 ligoje |
| TBX5T-box transcription factor 5 | Labai dažnai (80–99%) | 1 ligoje |
| TMEM43transmembrane protein 43 | Labai dažnai (80–99%) | 1 ligoje |
| TNNI2troponin I2, fast skeletal type | Labai dažnai (80–99%) | 2 ligose |
| TNNT3troponin T3, fast skeletal type | Labai dažnai (80–99%) | 2 ligose |
| TPM2tropomyosin 2 | Labai dažnai (80–99%) | 2 ligose |
| TRPV4transient receptor potential cation channel subfamily V member 4 | Labai dažnai (80–99%) | 2 ligose |
| ACTBactin beta | Dažnai (30–79%) | 1 ligoje |
| ACTG1actin gamma 1 | Dažnai (30–79%) | 1 ligoje |
| ANKRD55ankyrin repeat domain 55 | Dažnai (30–79%) | 1 ligoje |
| ASPAaspartoacylase | Dažnai (30–79%) | 1 ligoje |
| BAZ1Bbromodomain adjacent to zinc finger domain 1B | Dažnai (30–79%) | 1 ligoje |
| BRD4bromodomain containing 4 | Dažnai (30–79%) | 1 ligoje |
| BUD23BUD23 rRNA methyltransferase and ribosome maturation factor | Dažnai (30–79%) | 1 ligoje |
| CBScystathionine beta-synthase | Dažnai (30–79%) | 1 ligoje |
| CD247CD247 molecule | Dažnai (30–79%) | 1 ligoje |
| CHST11carbohydrate sulfotransferase 11 | Dažnai (30–79%) | 1 ligoje |
| CLIP2CAP-Gly domain containing linker protein 2 | Dažnai (30–79%) | 1 ligoje |
| DNAJC30DnaJ heat shock protein family (Hsp40) member C30 | Dažnai (30–79%) | 1 ligoje |
| EIF4Heukaryotic translation initiation factor 4H | Dažnai (30–79%) | 1 ligoje |
| ELNelastin | Dažnai (30–79%) | 1 ligoje |
| EZH2enhancer of zeste 2 polycomb repressive complex 2 subunit | Dažnai (30–79%) | 1 ligoje |
| FKBP6FKBP prolyl isomerase family member 6 (inactive) | Dažnai (30–79%) | 1 ligoje |
| FUZfuzzy planar cell polarity protein | Dažnai (30–79%) | 1 ligoje |
| GTF2Igeneral transcription factor IIi | Dažnai (30–79%) | 1 ligoje |
| GTF2IRD1GTF2I repeat domain containing 1 | Dažnai (30–79%) | 1 ligoje |
| GTF2IRD2GTF2I repeat domain containing 2 | Dažnai (30–79%) | 1 ligoje |
| GUSBglucuronidase beta | Dažnai (30–79%) | 2 ligose |
| HDAC8histone deacetylase 8 | Dažnai (30–79%) | 1 ligoje |
| HPGD15-hydroxyprostaglandin dehydrogenase | Dažnai (30–79%) | 1 ligoje |
| IDH1isocitrate dehydrogenase (NADP(+)) 1 | Dažnai (30–79%) | 1 ligoje |
| IDH2isocitrate dehydrogenase (NADP(+)) 2 | Dažnai (30–79%) | 1 ligoje |
| IL2RAinterleukin 2 receptor subunit alpha | Dažnai (30–79%) | 1 ligoje |
| IL2RBinterleukin 2 receptor subunit beta | Dažnai (30–79%) | 1 ligoje |
| LIMK1LIM domain kinase 1 | Dažnai (30–79%) | 1 ligoje |
| LTBP2latent transforming growth factor beta binding protein 2 | Dažnai (30–79%) | 2 ligose |
| MAU2MAU2 sister chromatid cohesion factor | Dažnai (30–79%) | 1 ligoje |
| METTL27methyltransferase like 27 | Dažnai (30–79%) | 1 ligoje |
| MYBPC1myosin binding protein C1 | Dažnai (30–79%) | 1 ligoje |
| NCF1neutrophil cytosolic factor 1 | Dažnai (30–79%) | 1 ligoje |
| NIPBLNIPBL cohesin loading factor | Dažnai (30–79%) | 1 ligoje |
| NPR2natriuretic peptide receptor 2 | Dažnai (30–79%) | 1 ligoje |
| NSD1nuclear receptor binding SET domain protein 1 | Dažnai (30–79%) | 1 ligoje |
| POMT1protein O-mannosyltransferase 1 | Dažnai (30–79%) | 1 ligoje |
| PTH1Rparathyroid hormone 1 receptor | Dažnai (30–79%) | 1 ligoje |
| PTPN2protein tyrosine phosphatase non-receptor type 2 | Dažnai (30–79%) | 1 ligoje |
| RAD21RAD21 cohesin complex component | Dažnai (30–79%) | 1 ligoje |
| RFC2replication factor C subunit 2 | Dažnai (30–79%) | 1 ligoje |
| SCUBE3signal peptide, CUB domain and EGF like domain containing 3 | Dažnai (30–79%) | 1 ligoje |
| SF3B4splicing factor 3b subunit 4 | Dažnai (30–79%) | 1 ligoje |
| SH3PXD2BSH3 and PX domains 2B | Dažnai (30–79%) | 1 ligoje |
| SLC26A2solute carrier family 26 member 2 | Dažnai (30–79%) | 2 ligose |
| SMC1Astructural maintenance of chromosomes 1A | Dažnai (30–79%) | 1 ligoje |
| SMC3structural maintenance of chromosomes 3 | Dažnai (30–79%) | 1 ligoje |
| STAT4signal transducer and activator of transcription 4 | Dažnai (30–79%) | 1 ligoje |
| STING1stimulator of interferon response cGAMP interactor 1 | Dažnai (30–79%) | 1 ligoje |
| STX1Asyntaxin 1A | Dažnai (30–79%) | 1 ligoje |
| SUMF1sulfatase modifying factor 1 | Dažnai (30–79%) | 1 ligoje |
| SUZ12SUZ12 polycomb repressive complex 2 subunit | Dažnai (30–79%) | 1 ligoje |
| TBL2transducin beta like 2 | Dažnai (30–79%) | 1 ligoje |
| TGDSTDP-glucose 4,6-dehydratase | Dažnai (30–79%) | 1 ligoje |
| TMEM270transmembrane protein 270 | Dažnai (30–79%) | 1 ligoje |
| USB1U6 snRNA biogenesis phosphodiesterase 1 | Dažnai (30–79%) | 1 ligoje |
| VANGL1VANGL planar cell polarity protein 1 | Dažnai (30–79%) | 1 ligoje |
| VPS33AVPS33A core subunit of CORVET and HOPS complexes | Dažnai (30–79%) | 1 ligoje |
| VPS37DVPS37D subunit of ESCRT-I | Dažnai (30–79%) | 1 ligoje |
| ACTG2actin gamma 2, smooth muscle | Kartais (5–29%) | 1 ligoje |
| ADAMTS17ADAM metallopeptidase with thrombospondin type 1 motif 17 | Kartais (5–29%) | 1 ligoje |
| AGAaspartylglucosaminidase | Kartais (5–29%) | 1 ligoje |
| AKT1AKT serine/threonine kinase 1 | Kartais (5–29%) | 1 ligoje |
| ANKHANKH inorganic pyrophosphate transport regulator | Kartais (5–29%) | 1 ligoje |
| ATRXATRX chromatin remodeler | Kartais (5–29%) | 1 ligoje |
| BMP6bone morphogenetic protein 6 | Kartais (5–29%) | 1 ligoje |
| CASZ1castor zinc finger 1 | Kartais (5–29%) | 1 ligoje |
| CCN2cellular communication network factor 2 | Kartais (5–29%) | 1 ligoje |
| CHMP1Acharged multivesicular body protein 1A | Kartais (5–29%) | 1 ligoje |
| CISD2CDGSH iron sulfur domain 2 | Kartais (5–29%) | 1 ligoje |
| COMPcartilage oligomeric matrix protein | Kartais (5–29%) | 3 ligose |
| EPG5ectopic P-granules 5 autophagy tethering factor | Kartais (5–29%) | 1 ligoje |
| FGFR3fibroblast growth factor receptor 3 | Kartais (5–29%) | 1 ligoje |
| GABRDgamma-aminobutyric acid type A receptor subunit delta | Kartais (5–29%) | 1 ligoje |
| HFEhomeostatic iron regulator | Kartais (5–29%) | 1 ligoje |
| HGSNATheparan-alpha-glucosaminide N-acetyltransferase | Kartais (5–29%) | 1 ligoje |
| INPPL1inositol polyphosphate phosphatase like 1 | Kartais (5–29%) | 1 ligoje |
| KCNAB2potassium voltage-gated channel subfamily A regulatory beta subunit 2 | Kartais (5–29%) | 1 ligoje |
| L1CAML1 cell adhesion molecule | Kartais (5–29%) | 1 ligoje |
| LEMD3LEM domain containing 3 | Kartais (5–29%) | 2 ligose |
| LTBP3latent transforming growth factor beta binding protein 3 | Kartais (5–29%) | 1 ligoje |
| LUZP1leucine zipper protein 1 | Kartais (5–29%) | 1 ligoje |
| MAN2B1mannosidase alpha class 2B member 1 | Kartais (5–29%) | 1 ligoje |
| MATN3matrilin 3 | Kartais (5–29%) | 1 ligoje |
| MECP2methyl-CpG binding protein 2 | Kartais (5–29%) | 1 ligoje |
| MMP23Bmatrix metallopeptidase 23B | Kartais (5–29%) | 1 ligoje |
| MTX2metaxin 2 | Kartais (5–29%) | 1 ligoje |
| NAE1NEDD8 activating enzyme E1 subunit 1 | Kartais (5–29%) | 1 ligoje |
| OCRLOCRL inositol polyphosphate-5-phosphatase | Kartais (5–29%) | 1 ligoje |
| PDPNpodoplanin | Kartais (5–29%) | 1 ligoje |
| PNKDPNKD metallo-beta-lactamase domain containing | Kartais (5–29%) | 1 ligoje |
| PPP1R12Aprotein phosphatase 1 regulatory subunit 12A | Kartais (5–29%) | 1 ligoje |
| PRDM16PR/SET domain 16 | Kartais (5–29%) | 1 ligoje |
| PRKCZprotein kinase C zeta | Kartais (5–29%) | 1 ligoje |
| PRRT2proline rich transmembrane protein 2 | Kartais (5–29%) | 1 ligoje |
| RAI1retinoic acid induced 1 | Kartais (5–29%) | 1 ligoje |
| REREarginine-glutamic acid dipeptide repeats | Kartais (5–29%) | 1 ligoje |
| RNU4ATACRNA, U4atac small nuclear | Kartais (5–29%) | 1 ligoje |
| SKISKI proto-oncogene | Kartais (5–29%) | 2 ligose |
| SPENspen family transcriptional repressor | Kartais (5–29%) | 1 ligoje |
| TNFRSF11BTNF receptor superfamily member 11b | Kartais (5–29%) | 1 ligoje |
| UBE4Bubiquitination factor E4B | Kartais (5–29%) | 1 ligoje |
| VAPBVAMP associated protein B and C | Kartais (5–29%) | 1 ligoje |
| WFS1wolframin ER transmembrane glycoprotein | Kartais (5–29%) | 1 ligoje |
| WRNWRN RecQ like helicase | Kartais (5–29%) | 1 ligoje |
| ZMPSTE24zinc metallopeptidase STE24 | Kartais (5–29%) | 1 ligoje |
| FLNAfilamin A | Retai (1–4 %) | 1 ligoje |
| PTBP1polypyrimidine tract binding protein 1 | Retai (1–4 %) | 1 ligoje |
| ARSBarylsulfatase B | Neužfiksuota | 1 ligoje |
| ASPNasporin | Neužfiksuota | 1 ligoje |
| CCN6cellular communication network factor 6 | Neužfiksuota | 1 ligoje |
| CD244CD244 molecule | Neužfiksuota | 1 ligoje |
| CIITAclass II major histocompatibility complex transactivator | Neužfiksuota | 1 ligoje |
| GNSglucosamine (N-acetyl)-6-sulfatase | Neužfiksuota | 1 ligoje |
| IL10interleukin 10 | Neužfiksuota | 1 ligoje |
| NAGLUN-acetyl-alpha-glucosaminidase | Neužfiksuota | 1 ligoje |
| NFKBIL1NFKB inhibitor like 1 | Neužfiksuota | 1 ligoje |
| PCYT1Aphosphate cytidylyltransferase 1A, choline | Neužfiksuota | 1 ligoje |
| PTF1Apancreas associated transcription factor 1a | Neužfiksuota | 1 ligoje |
| SGSHN-sulfoglucosamine sulfohydrolase | Neužfiksuota | 1 ligoje |
| SLC22A4solute carrier family 22 member 4 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
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- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
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