Pereiti prie turinio
Naudokite savo HSA ar FSA lėšas

Požymis

Enlarged male breast

Klinikinis pavadinimas: Gynecomastia

Abnormal development of large mammary glands in males resulting in breast enlargement.

HPO HP:0000771

Santrauka

Taip pat vadinama
Gynaecomastia
Kūno sistema
Abnormality of the breast

73 condition reports read genes linked to this trait

Dante Labs condition reports look at the genes behind groups of inherited conditions, read from one whole-genome test. Each page says which conditions and genes a report covers, how it is read and what it cannot tell you.

Show 69 more reports

Every condition report

Vienu tyrimu sužinokite genus, susijusius su Enlarged male breast, ir kitą jūsų genomo dalį.

Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites

Įsigyti savo Genome Test

99 genų susiję su Enlarged male breast

Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Enlarged male breast. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.

GenasKaip dažnai pasireiškiaLigos
PLAAT3phospholipase A and acyltransferase 3Visada1 ligoje
RFC4replication factor C subunit 4Visada1 ligoje
SCN4Asodium voltage-gated channel alpha subunit 4Visada1 ligoje
AKT2AKT serine/threonine kinase 2Labai dažnai (80–99%)2 ligose
ARandrogen receptorLabai dažnai (80–99%)5 ligose
CYP11A1cytochrome P450 family 11 subfamily A member 1Labai dažnai (80–99%)2 ligose
CYP19A1cytochrome P450 family 19 subfamily A member 1Labai dažnai (80–99%)1 ligoje
DHX37DEAH-box helicase 37Labai dažnai (80–99%)1 ligoje
GATA4GATA binding protein 4Labai dažnai (80–99%)1 ligoje
HDAC8histone deacetylase 8Labai dažnai (80–99%)1 ligoje
LAS1LLAS1 like ribosome biogenesis factorLabai dažnai (80–99%)2 ligose
LEPleptinLabai dažnai (80–99%)2 ligose
LEPRleptin receptorLabai dažnai (80–99%)1 ligoje
MAP3K1mitogen-activated protein kinase kinase kinase 1Labai dažnai (80–99%)1 ligoje
NR0B1nuclear receptor subfamily 0 group B member 1Labai dažnai (80–99%)1 ligoje
NR5A1nuclear receptor subfamily 5 group A member 1Labai dažnai (80–99%)1 ligoje
PHF6PHD finger protein 6Labai dažnai (80–99%)2 ligose
PNPLA6patatin like domain 6, lysophospholipaseLabai dažnai (80–99%)1 ligoje
RBM28RNA binding motif protein 28Labai dažnai (80–99%)2 ligose
RNF216ring finger protein 216Labai dažnai (80–99%)1 ligoje
SOX9SRY-box transcription factor 9Labai dažnai (80–99%)1 ligoje
SRYsex determining region YLabai dažnai (80–99%)3 ligose
VAMP7vesicle associated membrane protein 7Labai dažnai (80–99%)1 ligoje
WT1WT1 transcription factorLabai dažnai (80–99%)1 ligoje
WWOXWW domain containing oxidoreductaseLabai dažnai (80–99%)1 ligoje
ZFPM2zinc finger protein, FOG family member 2Labai dažnai (80–99%)1 ligoje
AIPAHR interacting HSP90 co-chaperoneDažnai (30–79%)1 ligoje
CDH23cadherin related 23Dažnai (30–79%)2 ligose
CHD7chromodomain helicase DNA binding protein 7Dažnai (30–79%)2 ligose
CPEcarboxypeptidase EDažnai (30–79%)1 ligoje
CUL4Bcullin 4BDažnai (30–79%)1 ligoje
CYP17A1cytochrome P450 family 17 subfamily A member 1Dažnai (30–79%)3 ligose
DESdesminDažnai (30–79%)1 ligoje
DUSP6dual specificity phosphatase 6Dažnai (30–79%)2 ligose
EMX2empty spiracles homeobox 2Dažnai (30–79%)2 ligose
FGF17fibroblast growth factor 17Dažnai (30–79%)2 ligose
FGF8fibroblast growth factor 8Dažnai (30–79%)2 ligose
FGFR1fibroblast growth factor receptor 1Dažnai (30–79%)3 ligose
FMR1fragile X messenger ribonucleoprotein 1Dažnai (30–79%)1 ligoje
GNRH1gonadotropin releasing hormone 1Dažnai (30–79%)1 ligoje
Rodyti dar 59 genų
GenasKaip dažnai pasireiškiaLigos
GNRHRgonadotropin releasing hormone receptorDažnai (30–79%)1 ligoje
HS6ST1heparan sulfate 6-O-sulfotransferase 1Dažnai (30–79%)2 ligose
HSD3B2hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2Dažnai (30–79%)1 ligoje
KISS1KiSS-1 metastasis suppressorDažnai (30–79%)1 ligoje
KISS1RKISS1 receptorDažnai (30–79%)2 ligose
LHBluteinizing hormone subunit betaDažnai (30–79%)1 ligoje
MEN1menin 1Dažnai (30–79%)1 ligoje
NHLH2nescient helix-loop-helix 2Dažnai (30–79%)1 ligoje
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factorDažnai (30–79%)2 ligose
PROK2prokineticin 2Dažnai (30–79%)2 ligose
PROKR2prokineticin receptor 2Dažnai (30–79%)2 ligose
SLC29A3solute carrier family 29 member 3Dažnai (30–79%)2 ligose
SMCHD1structural maintenance of chromosomes flexible hinge domain containing 1Dažnai (30–79%)1 ligoje
SPRY4sprouty RTK signaling antagonist 4Dažnai (30–79%)2 ligose
TAC3tachykinin precursor 3Dažnai (30–79%)1 ligoje
TACR3tachykinin receptor 3Dažnai (30–79%)2 ligose
TCF20transcription factor 20Dažnai (30–79%)1 ligoje
TTI1TELO2 interacting protein 1Dažnai (30–79%)1 ligoje
WDR11WD repeat domain 11Dažnai (30–79%)2 ligose
ZBTB20zinc finger and BTB domain containing 20Dažnai (30–79%)2 ligose
AFF4ALF transcription elongation factor 4Kartais (5–29%)1 ligoje
ALMS1ALMS1 centrosome and basal body associated proteinKartais (5–29%)2 ligose
ANOS1anosmin 1Kartais (5–29%)2 ligose
BCL11ABCL11 transcription factor AKartais (5–29%)1 ligoje
BMP6bone morphogenetic protein 6Kartais (5–29%)1 ligoje
CCDC141coiled-coil domain containing 141Kartais (5–29%)1 ligoje
CYB5Acytochrome b5 type AKartais (5–29%)1 ligoje
CYP11B1cytochrome P450 family 11 subfamily B member 1Kartais (5–29%)1 ligoje
DCCDCC netrin 1 receptorKartais (5–29%)1 ligoje
ERMARDER membrane associated RNA degradationKartais (5–29%)1 ligoje
FEZF1FEZ family zinc finger 1Kartais (5–29%)1 ligoje
FLRT3fibronectin leucine rich transmembrane protein 3Kartais (5–29%)1 ligoje
HESX1HESX homeobox 1Kartais (5–29%)1 ligoje
HFEhomeostatic iron regulatorKartais (5–29%)1 ligoje
HPGD15-hydroxyprostaglandin dehydrogenaseKartais (5–29%)1 ligoje
HSD17B3hydroxysteroid 17-beta dehydrogenase 3Kartais (5–29%)2 ligose
IL17RDinterleukin 17 receptor DKartais (5–29%)1 ligoje
MECP2methyl-CpG binding protein 2Kartais (5–29%)1 ligoje
NDNFneuron derived neurotrophic factorKartais (5–29%)1 ligoje
PDE11Aphosphodiesterase 11AKartais (5–29%)1 ligoje
POLR3ARNA polymerase III subunit AKartais (5–29%)2 ligose
PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alphaKartais (5–29%)1 ligoje
PSMB8proteasome 20S subunit beta 8Kartais (5–29%)1 ligoje
PTENphosphatase and tensin homologKartais (5–29%)2 ligose
RELREL proto-oncogene, NF-kB subunitKartais (5–29%)1 ligoje
SEMA3Asemaphorin 3AKartais (5–29%)1 ligoje
SH3PXD2BSH3 and PX domains 2BKartais (5–29%)1 ligoje
SLCO2A1solute carrier organic anion transporter family member 2A1Kartais (5–29%)1 ligoje
SMC5structural maintenance of chromosomes 5Kartais (5–29%)1 ligoje
SOX10SRY-box transcription factor 10Kartais (5–29%)1 ligoje
TMEM53transmembrane protein 53Kartais (5–29%)1 ligoje
XPO1exportin 1Kartais (5–29%)1 ligoje
COQ8Acoenzyme Q8ARetai (1–4 %)1 ligoje
SPTBN1spectrin beta, non-erythrocytic 1Retai (1–4 %)1 ligoje
CYP21A2cytochrome P450 family 21 subfamily A member 2Neužfiksuota1 ligoje
ITGA3integrin subunit alpha 3Neužfiksuota1 ligoje
PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alphaNeužfiksuota1 ligoje
RSPO1R-spondin 1Neužfiksuota1 ligoje
STK11serine/threonine kinase 11Neužfiksuota1 ligoje

Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.

Platesni požymiai

Abnormal breast morphology

Iš kur tai žinoma

  • Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
  • Duomenų leidimas 2026.10.19-9814e911.

From traits to your genome

Read the genes behind these traits in your own DNA.

The Genome Test sequences nearly all of your DNA, not a preset panel, so every gene on these pages is in your data. Premium adds 810+ physician-ready reports.

Nuo 449 $

Nemokamas pristatymas · Rezultatai per 6–8 savaites

Get my Genome TestSee the condition reports