Tunnus
Poor nail formation
Kliiniline nimetus: Nail dystrophy
Onychodystrophy (nail dystrophy) refers to nail changes apart from changes of the color (nail dyschromia) and involves partial or complete disruption of the various keratinous layers of the nail plate.
Kokkuvõte
- Teised nimetused
- Dystrophic nails, Onychodystrophy
- Kehasüsteem
- Abnormality of the integument
VõrdlusgenoomGRCh38hg38
Geeni- ja variandilehtede positsioonid järgivad seda valikut selles brauseris.
Read the genes linked to Poor nail formation, and the rest of your genome, with one test.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast
Telli oma Genome Test130 geeni on seotud tunnusega Poor nail formation
Nende geenide muutused põhjustavad haruldasi haigusi, mille puhul esineb Poor nail formation. Enamikul selle tunnusega inimestest ei ole ühtegi neist haigustest. Selles loendis olev geen ei ütle midagi kellegi enda genoomi kohta.
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| ATP6V1B2ATPase H+ transporting V1 subunit B2 | Alati | Esineb 1 haiguses |
| COL17A1collagen type XVII alpha 1 chain | Alati | Esineb 5 haiguses |
| COL7A1collagen type VII alpha 1 chain | Alati | Esineb 13 haiguses |
| DKC1dyskerin pseudouridine synthase 1 | Alati | Esineb 3 haiguses |
| DSG1desmoglein 1 | Alati | Esineb 1 haiguses |
| GRHL2grainyhead like transcription factor 2 | Alati | Esineb 1 haiguses |
| HOXC13homeobox C13 | Alati | Esineb 1 haiguses |
| ITGA3integrin subunit alpha 3 | Alati | Esineb 1 haiguses |
| ITGB4integrin subunit beta 4 | Alati | Esineb 6 haiguses |
| KRT14keratin 14 | Alati | Esineb 7 haiguses |
| KRT16keratin 16 | Alati | Esineb 2 haiguses |
| KRT17keratin 17 | Alati | Esineb 2 haiguses |
| KRT5keratin 5 | Alati | Esineb 7 haiguses |
| KRT6Akeratin 6A | Alati | Esineb 3 haiguses |
| KRT6Bkeratin 6B | Alati | Esineb 3 haiguses |
| KRT85keratin 85 | Alati | Esineb 1 haiguses |
| LAMA3laminin subunit alpha 3 | Alati | Esineb 5 haiguses |
| LAMB3laminin subunit beta 3 | Alati | Esineb 4 haiguses |
| MARS1methionyl-tRNA synthetase 1 | Alati | Esineb 1 haiguses |
| MPLKIPM-phase specific PLK1 interacting protein | Alati | Esineb 1 haiguses |
| NHEJ1non-homologous end joining factor 1 | Alati | Esineb 1 haiguses |
| NHP2NHP2 ribonucleoprotein | Alati | Esineb 3 haiguses |
| NLRP1NLR family pyrin domain containing 1 | Alati | Esineb 1 haiguses |
| NOP10NOP10 ribonucleoprotein | Alati | Esineb 2 haiguses |
| PKP1plakophilin 1 | Alati | Esineb 2 haiguses |
| PLECplectin | Alati | Esineb 4 haiguses |
| RNU6ATACRNA, U6atac small nuclear | Alati | Esineb 1 haiguses |
| SASH1SAM and SH3 domain containing 1 | Alati | Esineb 1 haiguses |
| STING1stimulator of interferon response cGAMP interactor 1 | Alati | Esineb 1 haiguses |
| TINF2TERF1 interacting nuclear factor 2 | Alati | Esineb 6 haiguses |
| TP63tumor protein p63 | Alati | Esineb 4 haiguses |
| TYMSthymidylate synthetase | Alati | Esineb 2 haiguses |
| WNT10AWnt family member 10A | Alati | Esineb 1 haiguses |
| WRAP53WD repeat containing antisense to TP53 | Alati | Esineb 2 haiguses |
| WRNWRN RecQ like helicase | Alati | Esineb 1 haiguses |
| ABCA12ATP binding cassette subfamily A member 12 | Väga sageli (80–99%) | Esineb 1 haiguses |
| ACDACD shelterin complex subunit and telomerase recruitment factor | Väga sageli (80–99%) | Esineb 3 haiguses |
| ALOX12Barachidonate 12-lipoxygenase, 12R type | Väga sageli (80–99%) | Esineb 1 haiguses |
| ALOXE3arachidonate epidermal lipoxygenase 3 | Väga sageli (80–99%) | Esineb 1 haiguses |
| ASPRV1aspartic peptidase retroviral like 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
Näita veel 90 geeni
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| CTC1CST telomere replication complex component 1 | Väga sageli (80–99%) | Esineb 2 haiguses |
| CTNNB1catenin beta 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| CYP4F22cytochrome P450 family 4 subfamily F member 22 | Väga sageli (80–99%) | Esineb 1 haiguses |
| DNA2DNA replication helicase/nuclease 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| EVCEvC ciliary complex subunit 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| EVC2EvC ciliary complex subunit 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| GJA1gap junction protein alpha 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| KDF1keratinocyte differentiation factor 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| LIPNlipase family member N | Väga sageli (80–99%) | Esineb 1 haiguses |
| LSSlanosterol synthase | Väga sageli (80–99%) | Esineb 1 haiguses |
| NIPAL4NIPA like domain containing 4 | Väga sageli (80–99%) | Esineb 1 haiguses |
| NPM1nucleophosmin 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| PARNpoly(A)-specific ribonuclease | Väga sageli (80–99%) | Esineb 3 haiguses |
| PORCNporcupine O-acyltransferase | Väga sageli (80–99%) | Esineb 2 haiguses |
| RTEL1regulator of telomere elongation helicase 1 | Väga sageli (80–99%) | Esineb 3 haiguses |
| SDR9C7short chain dehydrogenase/reductase family 9C member 7 | Väga sageli (80–99%) | Esineb 1 haiguses |
| SULT2B1sulfotransferase family 2B member 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| TERCtelomerase RNA component | Väga sageli (80–99%) | Esineb 3 haiguses |
| TERTtelomerase reverse transcriptase | Väga sageli (80–99%) | Esineb 4 haiguses |
| TGM1transglutaminase 1 | Väga sageli (80–99%) | Esineb 3 haiguses |
| USB1U6 snRNA biogenesis phosphodiesterase 1 | Väga sageli (80–99%) | Esineb 2 haiguses |
| ABCA1ATP binding cassette subfamily A member 1 | Sageli (30–79%) | Esineb 2 haiguses |
| AIREautoimmune regulator | Sageli (30–79%) | Esineb 2 haiguses |
| BANF1barrier to autointegration nuclear assembly factor 1 | Sageli (30–79%) | Esineb 1 haiguses |
| CD28CD28 molecule | Sageli (30–79%) | Esineb 1 haiguses |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Sageli (30–79%) | Esineb 1 haiguses |
| CTSCcathepsin C | Sageli (30–79%) | Esineb 1 haiguses |
| DCLRE1BDNA cross-link repair 1B | Sageli (30–79%) | Esineb 1 haiguses |
| DSPdesmoplakin | Sageli (30–79%) | Esineb 2 haiguses |
| FOXN1forkhead box N1 | Sageli (30–79%) | Esineb 2 haiguses |
| GJB2gap junction protein beta 2 | Sageli (30–79%) | Esineb 2 haiguses |
| GJB6gap junction protein beta 6 | Sageli (30–79%) | Esineb 3 haiguses |
| IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gamma | Sageli (30–79%) | Esineb 3 haiguses |
| KRT1keratin 1 | Sageli (30–79%) | Esineb 1 haiguses |
| LAMC2laminin subunit gamma 2 | Sageli (30–79%) | Esineb 3 haiguses |
| MMP1matrix metallopeptidase 1 | Sageli (30–79%) | Esineb 1 haiguses |
| NECTIN1nectin cell adhesion molecule 1 | Sageli (30–79%) | Esineb 1 haiguses |
| NFKB2nuclear factor kappa B subunit 2 | Sageli (30–79%) | Esineb 1 haiguses |
| POLD3DNA polymerase delta 3, accessory subunit | Sageli (30–79%) | Esineb 1 haiguses |
| PQBP1polyglutamine binding protein 1 | Sageli (30–79%) | Esineb 1 haiguses |
| RBCK1RANBP2-type and C3HC4-type zinc finger containing 1 | Sageli (30–79%) | Esineb 1 haiguses |
| RECQL4RecQ like helicase 4 | Sageli (30–79%) | Esineb 1 haiguses |
| TNFRSF1BTNF receptor superfamily member 1B | Sageli (30–79%) | Esineb 1 haiguses |
| UBE2Aubiquitin conjugating enzyme E2 A | Sageli (30–79%) | Esineb 2 haiguses |
| ZMPSTE24zinc metallopeptidase STE24 | Sageli (30–79%) | Esineb 1 haiguses |
| ANAPC1anaphase promoting complex subunit 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| ATRATR checkpoint kinase | Mõnikord (5–29%) | Esineb 1 haiguses |
| CDSNcorneodesmosin | Mõnikord (5–29%) | Esineb 1 haiguses |
| COX7Bcytochrome c oxidase subunit 7B | Mõnikord (5–29%) | Esineb 1 haiguses |
| CSTAcystatin A | Mõnikord (5–29%) | Esineb 1 haiguses |
| FGFR2fibroblast growth factor receptor 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| FOCADfocadhesin | Mõnikord (5–29%) | Esineb 1 haiguses |
| FOXP3forkhead box P3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| GABBR1gamma-aminobutyric acid type B receptor subunit 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| IL36RNinterleukin 36 receptor antagonist | Mõnikord (5–29%) | Esineb 1 haiguses |
| ITGA6integrin subunit alpha 6 | Mõnikord (5–29%) | Esineb 2 haiguses |
| KIF15kinesin family member 15 | Mõnikord (5–29%) | Esineb 1 haiguses |
| KMT2Dlysine methyltransferase 2D | Mõnikord (5–29%) | Esineb 1 haiguses |
| LORICRINloricrin cornified envelope precursor protein | Mõnikord (5–29%) | Esineb 1 haiguses |
| LRP1LDL receptor related protein 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MAFMAF bZIP transcription factor | Mõnikord (5–29%) | Esineb 1 haiguses |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Mõnikord (5–29%) | Esineb 3 haiguses |
| MTX2metaxin 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MVKmevalonate kinase | Mõnikord (5–29%) | Esineb 1 haiguses |
| NAF1nuclear assembly factor 1 ribonucleoprotein | Mõnikord (5–29%) | Esineb 1 haiguses |
| NFKBIANFKB inhibitor alpha | Mõnikord (5–29%) | Esineb 1 haiguses |
| PPP1R13Lprotein phosphatase 1 regulatory subunit 13 like | Mõnikord (5–29%) | Esineb 1 haiguses |
| RPA1replication protein A1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SAT1spermidine/spermine N1-acetyltransferase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SEL1LSEL1L adaptor subunit of SYVN1 ubiquitin ligase | Mõnikord (5–29%) | Esineb 1 haiguses |
| SMARCAD1SNF2 related chromatin remodeling ATPase with DExD box 1 | Mõnikord (5–29%) | Esineb 2 haiguses |
| SREBF1sterol regulatory element binding transcription factor 1 | Mõnikord (5–29%) | Esineb 2 haiguses |
| AAGABalpha and gamma adaptin binding protein | Harva (1–4%) | Esineb 1 haiguses |
| COL14A1collagen type XIV alpha 1 chain | Harva (1–4%) | Esineb 1 haiguses |
| GSNgelsolin | Harva (1–4%) | Esineb 1 haiguses |
| PI4KAphosphatidylinositol 4-kinase alpha | Harva (1–4%) | Esineb 1 haiguses |
| TTC7Atetratricopeptide repeat domain 7A | Harva (1–4%) | Esineb 1 haiguses |
| AP1S3adaptor related protein complex 1 subunit sigma 3 | Pole registreeritud | Esineb 1 haiguses |
| ATL1atlastin GTPase 1 | Pole registreeritud | Esineb 1 haiguses |
| CD151CD151 molecule (Raph blood group) | Pole registreeritud | Esineb 1 haiguses |
| DNAJC21DnaJ heat shock protein family (Hsp40) member C21 | Pole registreeritud | Esineb 1 haiguses |
| ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit | Pole registreeritud | Esineb 1 haiguses |
| FLNAfilamin A | Pole registreeritud | Esineb 1 haiguses |
| JUPjunction plakoglobin | Pole registreeritud | Esineb 1 haiguses |
| KRT86keratin 86 | Pole registreeritud | Esineb 1 haiguses |
| NTRK1neurotrophic receptor tyrosine kinase 1 | Pole registreeritud | Esineb 1 haiguses |
| POMPproteasome maturation protein | Pole registreeritud | Esineb 1 haiguses |
| RSPO1R-spondin 1 | Pole registreeritud | Esineb 1 haiguses |
| TRPV3transient receptor potential cation channel subfamily V member 3 | Pole registreeritud | Esineb 1 haiguses |
Kui sageli see esineb geenist tulenevate seisunditega inimeste seas, kõige sagedamini nende kõigi seas, nagu on märgitud Inimese fenotüübi ontoloogias. Need lehed kirjeldavad tunnuseid ja nende taga olevaid uuringuid; need ei ole diagnoos ning sümptomite kohta tuleks küsida arstilt või geneetilt nõustajalt.
Kitsamad tunnused
Laiemad tunnused
Allikas
- Inimese fenotüübi ontoloogia, versioon 2026-09-01: tunnus, selle nimetused, määratlus ja sellega seotud geenid. Lisateave leiab aadressilt hpo.jax.org.
- Andmeversioon 2026.10.16-c6eea6bf.
Üks test. Vastused kogu eluks.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast