Tunnus
Abnormality of the nail
Kliiniline nimetus: Abnormal nail morphology
Abnormal structure or appearance of the nail.
Kokkuvõte
- Teised nimetused
- Nail disease
- Kehasüsteem
- Abnormality of the integument
VõrdlusgenoomGRCh38hg38
Geeni- ja variandilehtede positsioonid järgivad seda valikut selles brauseris.
Read the genes linked to Abnormality of the nail, and the rest of your genome, with one test.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast
Telli oma Genome Test85 geeni on seotud tunnusega Abnormality of the nail
Nende geenide muutused põhjustavad haruldasi haigusi, mille puhul esineb Abnormality of the nail. Enamikul selle tunnusega inimestest ei ole ühtegi neist haigustest. Selles loendis olev geen ei ütle midagi kellegi enda genoomi kohta.
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| LAMC2laminin subunit gamma 2 | Alati | Esineb 2 haiguses |
| ACANaggrecan | Väga sageli (80–99%) | Esineb 1 haiguses |
| AP1S3adaptor related protein complex 1 subunit sigma 3 | Väga sageli (80–99%) | Esineb 1 haiguses |
| ATP2A2ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| CLEC7AC-type lectin domain containing 7A | Väga sageli (80–99%) | Esineb 1 haiguses |
| DSG4desmoglein 4 | Väga sageli (80–99%) | Esineb 1 haiguses |
| DYNC2LI1dynein cytoplasmic 2 light intermediate chain 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| EVCEvC ciliary complex subunit 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| EVC2EvC ciliary complex subunit 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| GJA1gap junction protein alpha 1 | Väga sageli (80–99%) | Esineb 3 haiguses |
| GLI1GLI family zinc finger 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| HLA-Bmajor histocompatibility complex, class I, B | Väga sageli (80–99%) | Esineb 1 haiguses |
| IL17Finterleukin 17F | Väga sageli (80–99%) | Esineb 1 haiguses |
| IL17RAinterleukin 17 receptor A | Väga sageli (80–99%) | Esineb 1 haiguses |
| IL17RCinterleukin 17 receptor C | Väga sageli (80–99%) | Esineb 1 haiguses |
| IL36RNinterleukin 36 receptor antagonist | Väga sageli (80–99%) | Esineb 1 haiguses |
| KRT81keratin 81 | Väga sageli (80–99%) | Esineb 1 haiguses |
| KRT83keratin 83 | Väga sageli (80–99%) | Esineb 1 haiguses |
| KRT86keratin 86 | Väga sageli (80–99%) | Esineb 1 haiguses |
| LAMA3laminin subunit alpha 3 | Väga sageli (80–99%) | Esineb 1 haiguses |
| LAMB3laminin subunit beta 3 | Väga sageli (80–99%) | Esineb 1 haiguses |
| LMX1BLIM homeobox transcription factor 1 beta | Väga sageli (80–99%) | Esineb 1 haiguses |
| MSX1msh homeobox 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| PDE4Dphosphodiesterase 4D | Väga sageli (80–99%) | Esineb 1 haiguses |
| PRKACAprotein kinase cAMP-activated catalytic subunit alpha | Väga sageli (80–99%) | Esineb 1 haiguses |
| PRKACBprotein kinase cAMP-activated catalytic subunit beta | Väga sageli (80–99%) | Esineb 1 haiguses |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Väga sageli (80–99%) | Esineb 1 haiguses |
| SLC25A24solute carrier family 25 member 24 | Väga sageli (80–99%) | Esineb 1 haiguses |
| SMARCAD1SNF2 related chromatin remodeling ATPase with DExD box 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| TP63tumor protein p63 | Väga sageli (80–99%) | Esineb 1 haiguses |
| TRAF3IP2TRAF3 interacting protein 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| ABCA12ATP binding cassette subfamily A member 12 | Sageli (30–79%) | Esineb 1 haiguses |
| ALOX12Barachidonate 12-lipoxygenase, 12R type | Sageli (30–79%) | Esineb 1 haiguses |
| ALOXE3arachidonate epidermal lipoxygenase 3 | Sageli (30–79%) | Esineb 1 haiguses |
| CARD14caspase recruitment domain family member 14 | Sageli (30–79%) | Esineb 1 haiguses |
| CASRcalcium sensing receptor | Sageli (30–79%) | Esineb 1 haiguses |
| CERS3ceramide synthase 3 | Sageli (30–79%) | Esineb 1 haiguses |
| CTSCcathepsin C | Sageli (30–79%) | Esineb 1 haiguses |
| CTSKcathepsin K | Sageli (30–79%) | Esineb 1 haiguses |
| CYB5Acytochrome b5 type A | Sageli (30–79%) | Esineb 1 haiguses |
Näita veel 45 geeni
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| CYB5R3cytochrome b5 reductase 3 | Sageli (30–79%) | Esineb 1 haiguses |
| DLX3distal-less homeobox 3 | Sageli (30–79%) | Esineb 1 haiguses |
| DSG1desmoglein 1 | Sageli (30–79%) | Esineb 1 haiguses |
| DSPdesmoplakin | Sageli (30–79%) | Esineb 1 haiguses |
| GNA11G protein subunit alpha 11 | Sageli (30–79%) | Esineb 1 haiguses |
| HGDhomogentisate 1,2-dioxygenase | Sageli (30–79%) | Esineb 1 haiguses |
| IFT140intraflagellar transport 140 | Sageli (30–79%) | Esineb 1 haiguses |
| IRF6interferon regulatory factor 6 | Sageli (30–79%) | Esineb 1 haiguses |
| KRT1keratin 1 | Sageli (30–79%) | Esineb 1 haiguses |
| LMNAlamin A/C | Sageli (30–79%) | Esineb 2 haiguses |
| MAP3K20mitogen-activated protein kinase kinase kinase 20 | Sageli (30–79%) | Esineb 1 haiguses |
| MBTPS2membrane bound transcription factor peptidase, site 2 | Sageli (30–79%) | Esineb 1 haiguses |
| NIPAL4NIPA like domain containing 4 | Sageli (30–79%) | Esineb 1 haiguses |
| PNPLA1patatin like domain 1, omega-hydroxyceramide transacylase | Sageli (30–79%) | Esineb 1 haiguses |
| SDR9C7short chain dehydrogenase/reductase family 9C member 7 | Sageli (30–79%) | Esineb 1 haiguses |
| SLC39A4solute carrier family 39 member 4 | Sageli (30–79%) | Esineb 1 haiguses |
| SULT2B1sulfotransferase family 2B member 1 | Sageli (30–79%) | Esineb 1 haiguses |
| TGM1transglutaminase 1 | Sageli (30–79%) | Esineb 1 haiguses |
| ADNPactivity dependent neuroprotector homeobox | Mõnikord (5–29%) | Esineb 1 haiguses |
| AKT1AKT serine/threonine kinase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| CD28CD28 molecule | Mõnikord (5–29%) | Esineb 1 haiguses |
| COX7Bcytochrome c oxidase subunit 7B | Mõnikord (5–29%) | Esineb 1 haiguses |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Mõnikord (5–29%) | Esineb 1 haiguses |
| EBPEBP cholestenol delta-isomerase | Mõnikord (5–29%) | Esineb 1 haiguses |
| FBXO22F-box protein 22 | Mõnikord (5–29%) | Esineb 1 haiguses |
| FGF9fibroblast growth factor 9 | Mõnikord (5–29%) | Esineb 1 haiguses |
| FGFR2fibroblast growth factor receptor 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| FUCA1alpha-L-fucosidase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| GDF5growth differentiation factor 5 | Mõnikord (5–29%) | Esineb 1 haiguses |
| GDF6growth differentiation factor 6 | Mõnikord (5–29%) | Esineb 1 haiguses |
| GJB2gap junction protein beta 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| GJB3gap junction protein beta 3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| GJB4gap junction protein beta 4 | Mõnikord (5–29%) | Esineb 1 haiguses |
| HCCSholocytochrome c synthase | Mõnikord (5–29%) | Esineb 1 haiguses |
| HRHR lysine demethylase and nuclear receptor corepressor | Mõnikord (5–29%) | Esineb 1 haiguses |
| KDSR3-ketodihydrosphingosine reductase | Mõnikord (5–29%) | Esineb 1 haiguses |
| LEF1lymphoid enhancer binding factor 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| NDUFB11NADH:ubiquinone oxidoreductase subunit B11 | Mõnikord (5–29%) | Esineb 1 haiguses |
| NOGnoggin | Mõnikord (5–29%) | Esineb 1 haiguses |
| TATtyrosine aminotransferase | Mõnikord (5–29%) | Esineb 1 haiguses |
| TNFRSF1BTNF receptor superfamily member 1B | Mõnikord (5–29%) | Esineb 1 haiguses |
| TREX1three prime repair exonuclease 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| CDSNcorneodesmosin | Pole registreeritud | Esineb 1 haiguses |
| KRT74keratin 74 | Pole registreeritud | Esineb 1 haiguses |
| UBR1ubiquitin protein ligase E3 component n-recognin 1 | Pole registreeritud | Esineb 1 haiguses |
Kui sageli see esineb geenist tulenevate seisunditega inimeste seas, kõige sagedamini nende kõigi seas, nagu on märgitud Inimese fenotüübi ontoloogias. Need lehed kirjeldavad tunnuseid ja nende taga olevaid uuringuid; need ei ole diagnoos ning sümptomite kohta tuleks küsida arstilt või geneetilt nõustajalt.
Kitsamad tunnused
- Poor nail formation130 geeni
- Abnormal fingernails99 geeni
- Atypical nail growth84 geeni
- Brittle nails35 geeni
- Abnormality of the toenail33 geeni
- Thick nail19 geeni
- Absent/small nails16 geeni
- Thin nail16 geeni
- Abnormal periungual morphology3 geeni
- Abnormality of nail color3 geeni
- Nailfold capillary tortuosity3 geeni
- Chronic monilial nail infection2 geeni
- Nail bed hemorrhage2 geeni
- Nail bed telangiectasia2 geeni
- Abnormal subungual morphology1 geen
- Longitudinal erythronychia1 geen
- Onychoheterotopia1 geen
- Pyramidal skinfold extending from the base to the top of the nails1 geen
- Splinter hemorrhages1 geen
- Abnormal nail attachment
- Abnormal nail growth
- Abnormal nail surface
- Nail tumor
Laiemad tunnused
Allikas
- Inimese fenotüübi ontoloogia, versioon 2026-09-01: tunnus, selle nimetused, määratlus ja sellega seotud geenid. Lisateave leiab aadressilt hpo.jax.org.
- Andmeversioon 2026.10.16-c6eea6bf.
Üks test. Vastused kogu eluks.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast