Požymis
Decreased ability to exercise
Klinikinis pavadinimas: Exercise intolerance
A functional motor deficit where individuals whose responses to the challenges of exercise fail to achieve levels considered normal for their age and gender.
Santrauka
- Taip pat vadinama
- Inability to exercise, Low exercise endurance, Poor exercise tolerance
- Kūno sistema
- Constitutional symptom
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Decreased ability to exercise, and the rest of your genome, with one test.
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Įsigyti savo Genome Test171 genas susijęs su Decreased ability to exercise
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Decreased ability to exercise. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| ATP5F1DATP synthase F1 subunit delta | Visada | 2 ligose |
| COA3cytochrome c oxidase assembly factor 3 | Visada | 1 ligoje |
| COL13A1collagen type XIII alpha 1 chain | Visada | 1 ligoje |
| FARSAphenylalanyl-tRNA synthetase subunit alpha | Visada | 1 ligoje |
| FARSBphenylalanyl-tRNA synthetase subunit beta | Visada | 1 ligoje |
| FASTKD5FASTK mitochondrial RNA regulator 5 | Visada | 1 ligoje |
| GAAalpha glucosidase | Visada | 1 ligoje |
| GYS1glycogen synthase 1 | Visada | 2 ligose |
| HSPB8heat shock protein family B (small) member 8 | Visada | 1 ligoje |
| ISCUiron-sulfur cluster assembly enzyme | Visada | 1 ligoje |
| JPH1junctophilin 1 | Visada | 1 ligoje |
| MIEF2mitochondrial elongation factor 2 | Visada | 1 ligoje |
| MLIPmuscular LMNA interacting protein | Visada | 1 ligoje |
| MPV17mitochondrial inner membrane protein MPV17 | Visada | 1 ligoje |
| MSL2MSL complex subunit 2 | Visada | 1 ligoje |
| PACSIN3protein kinase C and casein kinase substrate in neurons 3 | Visada | 1 ligoje |
| PHKA1phosphorylase kinase regulatory subunit alpha 1 | Visada | 2 ligose |
| PIEZO2piezo type mechanosensitive ion channel component 2 | Visada | 1 ligoje |
| POLGDNA polymerase gamma, catalytic subunit | Visada | 5 ligose |
| POLG2DNA polymerase gamma 2, accessory subunit | Visada | 2 ligose |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Visada | 1 ligoje |
| SLC18A3solute carrier family 18 member A3 | Visada | 1 ligoje |
| SLC25A4solute carrier family 25 member 4 | Visada | 3 ligose |
| TAFAZZINtafazzin, phospholipid-lysophospholipid transacylase | Visada | 2 ligose |
| TMEM126Btransmembrane protein 126B | Visada | 1 ligoje |
| TOP3ADNA topoisomerase III alpha | Visada | 2 ligose |
| TRMT5tRNA methyltransferase 5 | Visada | 1 ligoje |
| CCDC78coiled-coil domain containing 78 | Labai dažnai (80–99%) | 1 ligoje |
| CPT2carnitine palmitoyltransferase 2 | Labai dažnai (80–99%) | 2 ligose |
| DMDdystrophin | Labai dažnai (80–99%) | 1 ligoje |
| ENO3enolase 3 | Labai dažnai (80–99%) | 2 ligose |
| HADHAhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha | Labai dažnai (80–99%) | 1 ligoje |
| HADHBhydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | Labai dažnai (80–99%) | 1 ligoje |
| PYGMglycogen phosphorylase, muscle associated | Labai dažnai (80–99%) | 2 ligose |
| RNASEH1ribonuclease H1 | Labai dažnai (80–99%) | 2 ligose |
| RRM2Bribonucleotide reductase regulatory TP53 inducible subunit M2B | Labai dažnai (80–99%) | 4 ligose |
| ABCC9ATP binding cassette subfamily C member 9 | Dažnai (30–79%) | 1 ligoje |
| ACTA1actin alpha 1, skeletal muscle | Dažnai (30–79%) | 1 ligoje |
| ACTC1actin alpha cardiac muscle 1 | Dažnai (30–79%) | 1 ligoje |
| ALDH4A1aldehyde dehydrogenase 4 family member A1 | Dažnai (30–79%) | 1 ligoje |
Rodyti dar 131 geną
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| C1QBPcomplement C1q binding protein | Dažnai (30–79%) | 1 ligoje |
| CHCHD10coiled-coil-helix-coiled-coil-helix domain containing 10 | Dažnai (30–79%) | 2 ligose |
| CITED2Cbp/p300 interacting transactivator with ED-rich tail 2 | Dažnai (30–79%) | 2 ligose |
| COQ8Acoenzyme Q8A | Dažnai (30–79%) | 2 ligose |
| DTNAdystrobrevin alpha | Dažnai (30–79%) | 1 ligoje |
| ETFAelectron transfer flavoprotein subunit alpha | Dažnai (30–79%) | 1 ligoje |
| ETFBelectron transfer flavoprotein subunit beta | Dažnai (30–79%) | 1 ligoje |
| ETFDHelectron transfer flavoprotein dehydrogenase | Dažnai (30–79%) | 1 ligoje |
| GATA4GATA binding protein 4 | Dažnai (30–79%) | 2 ligose |
| GATA5GATA binding protein 5 | Dažnai (30–79%) | 1 ligoje |
| GATA6GATA binding protein 6 | Dažnai (30–79%) | 2 ligose |
| GJA5gap junction protein alpha 5 | Dažnai (30–79%) | 1 ligoje |
| GLAgalactosidase alpha | Dažnai (30–79%) | 1 ligoje |
| GMPPBGDP-mannose pyrophosphorylase B | Dažnai (30–79%) | 2 ligose |
| HINT1histidine triad nucleotide binding protein 1 | Dažnai (30–79%) | 1 ligoje |
| KBTBD13kelch repeat and BTB domain containing 13 | Dažnai (30–79%) | 2 ligose |
| KCNA5potassium voltage-gated channel subfamily A member 5 | Dažnai (30–79%) | 1 ligoje |
| KCNE1potassium voltage-gated channel subfamily E regulatory subunit 1 | Dažnai (30–79%) | 1 ligoje |
| KCNE2potassium voltage-gated channel subfamily E regulatory subunit 2 | Dažnai (30–79%) | 1 ligoje |
| KCNJ2potassium inwardly rectifying channel subfamily J member 2 | Dažnai (30–79%) | 1 ligoje |
| KCNJ3potassium inwardly rectifying channel subfamily J member 3 | Dažnai (30–79%) | 1 ligoje |
| KCNJ5potassium inwardly rectifying channel subfamily J member 5 | Dažnai (30–79%) | 1 ligoje |
| KCNQ1potassium voltage-gated channel subfamily Q member 1 | Dažnai (30–79%) | 1 ligoje |
| KLHL41kelch like family member 41 | Dažnai (30–79%) | 1 ligoje |
| MGME1mitochondrial genome maintenance exonuclease 1 | Dažnai (30–79%) | 2 ligose |
| MRPS2mitochondrial ribosomal protein S2 | Dažnai (30–79%) | 1 ligoje |
| MT-TEmitochondrially encoded tRNA-Glu (GAA/G) | Dažnai (30–79%) | 1 ligoje |
| MT-TKmitochondrially encoded tRNA-Lys (AAA/G) | Dažnai (30–79%) | 1 ligoje |
| MYH6myosin heavy chain 6 | Dažnai (30–79%) | 1 ligoje |
| MYL4myosin light chain 4 | Dažnai (30–79%) | 1 ligoje |
| MYPNmyopalladin | Dažnai (30–79%) | 1 ligoje |
| NEBnebulin | Dažnai (30–79%) | 1 ligoje |
| NKX2-5NK2 homeobox 5 | Dažnai (30–79%) | 2 ligose |
| NKX2-6NK2 homeobox 6 | Dažnai (30–79%) | 1 ligoje |
| NPPAnatriuretic peptide A | Dažnai (30–79%) | 1 ligoje |
| NUP155nucleoporin 155 | Dažnai (30–79%) | 1 ligoje |
| OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | Dažnai (30–79%) | 1 ligoje |
| PFKMphosphofructokinase, muscle | Dažnai (30–79%) | 1 ligoje |
| PGAM2phosphoglycerate mutase 2 | Dažnai (30–79%) | 2 ligose |
| PGM1phosphoglucomutase 1 | Dažnai (30–79%) | 1 ligoje |
| PHKG1phosphorylase kinase catalytic subunit gamma 1 | Dažnai (30–79%) | 1 ligoje |
| PITX2paired like homeodomain 2 | Dažnai (30–79%) | 1 ligoje |
| POLR2ARNA polymerase II subunit A | Dažnai (30–79%) | 1 ligoje |
| SCN1Bsodium voltage-gated channel beta subunit 1 | Dažnai (30–79%) | 1 ligoje |
| SCN2Bsodium voltage-gated channel beta subunit 2 | Dažnai (30–79%) | 1 ligoje |
| SCN3Bsodium voltage-gated channel beta subunit 3 | Dažnai (30–79%) | 1 ligoje |
| SCN4Bsodium voltage-gated channel beta subunit 4 | Dažnai (30–79%) | 1 ligoje |
| SCN5Asodium voltage-gated channel alpha subunit 5 | Dažnai (30–79%) | 1 ligoje |
| SLC4A1solute carrier family 4 member 1 (Diego blood group) | Dažnai (30–79%) | 1 ligoje |
| TBX20T-box transcription factor 20 | Dažnai (30–79%) | 1 ligoje |
| TLL1tolloid like 1 | Dažnai (30–79%) | 2 ligose |
| TPM2tropomyosin 2 | Dažnai (30–79%) | 1 ligoje |
| TPM3tropomyosin 3 | Dažnai (30–79%) | 1 ligoje |
| TTNtitin | Dažnai (30–79%) | 1 ligoje |
| TWNKtwinkle mtDNA helicase | Dažnai (30–79%) | 3 ligose |
| YARS2tyrosyl-tRNA synthetase 2 | Dažnai (30–79%) | 1 ligoje |
| ABCA3ATP binding cassette subfamily A member 3 | Kartais (5–29%) | 1 ligoje |
| ACAD9acyl-CoA dehydrogenase family member 9 | Kartais (5–29%) | 1 ligoje |
| ATP11AATPase phospholipid transporting 11A | Kartais (5–29%) | 1 ligoje |
| ATP5F1AATP synthase F1 subunit alpha | Kartais (5–29%) | 1 ligoje |
| ATP5F1EATP synthase F1 subunit epsilon | Kartais (5–29%) | 1 ligoje |
| ATP5MKATP synthase membrane subunit k | Kartais (5–29%) | 1 ligoje |
| ATP5POATP synthase peripheral stalk subunit OSCP | Kartais (5–29%) | 1 ligoje |
| ATPAF2ATP synthase mitochondrial F1 complex assembly factor 2 | Kartais (5–29%) | 1 ligoje |
| COL12A1collagen type XII alpha 1 chain | Kartais (5–29%) | 1 ligoje |
| DOT1LDOT1 like histone lysine methyltransferase | Kartais (5–29%) | 1 ligoje |
| DPP9dipeptidyl peptidase 9 | Kartais (5–29%) | 1 ligoje |
| DSPdesmoplakin | Kartais (5–29%) | 1 ligoje |
| EPB41erythrocyte membrane protein band 4.1 | Kartais (5–29%) | 1 ligoje |
| FAM13Afamily with sequence similarity 13 member A | Kartais (5–29%) | 1 ligoje |
| GCDHglutaryl-CoA dehydrogenase | Kartais (5–29%) | 1 ligoje |
| GYPCglycophorin C (Gerbich blood group) | Kartais (5–29%) | 1 ligoje |
| HIVEP2HIVEP zinc finger 2 | Kartais (5–29%) | 1 ligoje |
| MT-ATP6mitochondrially encoded ATP synthase membrane subunit 6 | Kartais (5–29%) | 1 ligoje |
| MT-ATP8mitochondrially encoded ATP synthase membrane subunit 8 | Kartais (5–29%) | 2 ligose |
| MT-CO1mitochondrially encoded cytochrome c oxidase I | Kartais (5–29%) | 1 ligoje |
| MT-CO2mitochondrially encoded cytochrome c oxidase II | Kartais (5–29%) | 1 ligoje |
| MT-CO3mitochondrially encoded cytochrome c oxidase III | Kartais (5–29%) | 1 ligoje |
| MT-CYBmitochondrially encoded cytochrome b | Kartais (5–29%) | 1 ligoje |
| MT-ND1mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | Kartais (5–29%) | 1 ligoje |
| MT-ND4mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | Kartais (5–29%) | 1 ligoje |
| MT-ND5mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | Kartais (5–29%) | 1 ligoje |
| MT-ND6mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | Kartais (5–29%) | 1 ligoje |
| MT-TFmitochondrially encoded tRNA-Phe (UUU/C) | Kartais (5–29%) | 1 ligoje |
| MT-THmitochondrially encoded tRNA-His (CAU/C) | Kartais (5–29%) | 1 ligoje |
| MT-TL1mitochondrially encoded tRNA-Leu (UUA/G) 1 | Kartais (5–29%) | 2 ligose |
| MT-TQmitochondrially encoded tRNA-Gln (CAA/G) | Kartais (5–29%) | 1 ligoje |
| MT-TS1mitochondrially encoded tRNA-Ser (UCN) 1 | Kartais (5–29%) | 2 ligose |
| MT-TS2mitochondrially encoded tRNA-Ser (AGU/C) 2 | Kartais (5–29%) | 1 ligoje |
| MT-TWmitochondrially encoded tRNA-Trp (UGA/G) | Kartais (5–29%) | 1 ligoje |
| MUC5Bmucin 5B, oligomeric mucus/gel-forming | Kartais (5–29%) | 1 ligoje |
| PARNpoly(A)-specific ribonuclease | Kartais (5–29%) | 1 ligoje |
| PHKA2phosphorylase kinase regulatory subunit alpha 2 | Kartais (5–29%) | 1 ligoje |
| PHKBphosphorylase kinase regulatory subunit beta | Kartais (5–29%) | 1 ligoje |
| PHKG2phosphorylase kinase catalytic subunit gamma 2 | Kartais (5–29%) | 1 ligoje |
| PTPMT1protein tyrosine phosphatase mitochondrial 1 | Kartais (5–29%) | 1 ligoje |
| RRM1ribonucleotide reductase catalytic subunit M1 | Kartais (5–29%) | 1 ligoje |
| RTEL1regulator of telomere elongation helicase 1 | Kartais (5–29%) | 1 ligoje |
| SFTPA1surfactant protein A1 | Kartais (5–29%) | 1 ligoje |
| SFTPA2surfactant protein A2 | Kartais (5–29%) | 1 ligoje |
| SFTPCsurfactant protein C | Kartais (5–29%) | 1 ligoje |
| SPTA1spectrin alpha, erythrocytic 1 | Kartais (5–29%) | 1 ligoje |
| SPTBspectrin beta, erythrocytic | Kartais (5–29%) | 1 ligoje |
| STN1STN1 subunit of CST complex | Kartais (5–29%) | 1 ligoje |
| TERCtelomerase RNA component | Kartais (5–29%) | 1 ligoje |
| TERTtelomerase reverse transcriptase | Kartais (5–29%) | 1 ligoje |
| TK2thymidine kinase 2 | Kartais (5–29%) | 1 ligoje |
| AGKacylglycerol kinase | Neužfiksuota | 1 ligoje |
| BCS1LBCS1 ubiquinol-cytochrome c reductase complex chaperone | Neužfiksuota | 1 ligoje |
| CAVIN1caveolae associated protein 1 | Neužfiksuota | 1 ligoje |
| COX10cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 | Neužfiksuota | 1 ligoje |
| COX15cytochrome c oxidase assembly factor COX15 | Neužfiksuota | 1 ligoje |
| COX6B1cytochrome c oxidase subunit 6B1 | Neužfiksuota | 1 ligoje |
| DNA2DNA replication helicase/nuclease 2 | Neužfiksuota | 1 ligoje |
| FASTKD2FASTK mitochondrial RNA regulator 2 | Neužfiksuota | 1 ligoje |
| FLAD1flavin adenine dinucleotide synthetase 1 | Neužfiksuota | 1 ligoje |
| LAMP2lysosome associated membrane protein 2 | Neužfiksuota | 1 ligoje |
| LDHAlactate dehydrogenase A | Neužfiksuota | 1 ligoje |
| MT-TNmitochondrially encoded tRNA-Asn (AAU/C) | Neužfiksuota | 1 ligoje |
| NDUFS4NADH:ubiquinone oxidoreductase subunit S4 | Neužfiksuota | 1 ligoje |
| PGK1phosphoglycerate kinase 1 | Neužfiksuota | 1 ligoje |
| PNPLA2patatin like domain 2, triacylglycerol lipase | Neužfiksuota | 1 ligoje |
| POPDC1popeye domain cAMP effector 1 | Neužfiksuota | 1 ligoje |
| RSPH4Aradial spoke head component 4A | Neužfiksuota | 1 ligoje |
| RSPH9radial spoke head component 9 | Neužfiksuota | 1 ligoje |
| SCO1synthesis of cytochrome C oxidase 1 | Neužfiksuota | 1 ligoje |
| SCO2synthesis of cytochrome C oxidase 2 | Neužfiksuota | 1 ligoje |
| SDHAsuccinate dehydrogenase complex flavoprotein subunit A | Neužfiksuota | 1 ligoje |
| SLC25A32solute carrier family 25 member 32 | Neužfiksuota | 1 ligoje |
| SURF1SURF1 cytochrome c oxidase assembly factor | Neužfiksuota | 1 ligoje |
| TACO1translational activator of cytochrome c oxidase I | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
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- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
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