AtlasKam padedameMūsų mokslasProduktaiRezultatai
PrisijungtiKlaustiSekvenuokite savo genomą↗
Požymis
Liver failure
Klinikinis pavadinimas: Hepatic failure
Santrauka
- Taip pat vadinama
- Hepatic insufficiency
- Kūno sistema
- Abnormality of the digestive system
AtlasKam padedameMūsų mokslasProduktaiRezultatai
PrisijungtiKlaustiSekvenuokite savo genomą↗
Ši puslapis kaip duomenys
Norėdami perskaityti jį kaip JSON, pridėkite .json prie puslapio adreso arba nurodykite application/json.
library(jsonlite)
url <- "https://dantelabs.com/traits/hepatic-failure.json"
page <- fromJSON(url)
page$trait$nameLiver failureHP:0001399
AtlasKam padedameMūsų mokslasProduktaiRezultatai
PrisijungtiKlaustiSekvenuokite savo genomą↗
Vienu tyrimu sužinokite genus, susijusius su Liver failure, ir kitą jūsų genomo dalį.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites
Įsigyti savo Genome Test141 genas susijęs su Liver failure
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Liver failure. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| ABCD3ATP binding cassette subfamily D member 3 | Visada | 1 ligoje |
| APOA1apolipoprotein A1 | Visada | 1 ligoje |
| ATP7BATPase copper transporting beta | Visada | 1 ligoje |
| CYP7B1cytochrome P450 family 7 subfamily B member 1 | Visada | 2 ligose |
| DCDC2doublecortin domain containing 2 | Visada | 1 ligoje |
| DGUOKdeoxyguanosine kinase | Visada | 1 ligoje |
| F8coagulation factor VIII | Visada | 1 ligoje |
| FAHfumarylacetoacetate hydrolase | Visada | 1 ligoje |
| FHfumarate hydratase | Visada | 1 ligoje |
| IL18BPinterleukin 18 binding protein | Visada | 1 ligoje |
| IL27RAinterleukin 27 receptor subunit alpha | Visada | 1 ligoje |
| LIPAlipase A, lysosomal acid type | Visada | 3 ligose |
| MARS1methionyl-tRNA synthetase 1 | Visada | 1 ligoje |
| MRM2mitochondrial rRNA methyltransferase 2 | Visada | 1 ligoje |
| NR1H4nuclear receptor subfamily 1 group H member 4 | Visada | 1 ligoje |
| PCK1phosphoenolpyruvate carboxykinase 1 | Visada | 1 ligoje |
| PEX19peroxisomal biogenesis factor 19 | Visada | 2 ligose |
| PIGAphosphatidylinositol glycan anchor biosynthesis class A | Visada | 2 ligose |
| POT1protection of telomeres 1 | Visada | 1 ligoje |
| PSKH1protein serine kinase H1 | Visada | 1 ligoje |
| RFC4replication factor C subunit 4 | Visada | 1 ligoje |
| TFAMtranscription factor A, mitochondrial | Visada | 1 ligoje |
| UBR1ubiquitin protein ligase E3 component n-recognin 1 | Visada | 1 ligoje |
| CPT1Acarnitine palmitoyltransferase 1A | Labai dažnai (80–99%) | 1 ligoje |
| OTCornithine transcarbamylase | Labai dažnai (80–99%) | 1 ligoje |
| PEX1peroxisomal biogenesis factor 1 | Labai dažnai (80–99%) | 1 ligoje |
| PEX10peroxisomal biogenesis factor 10 | Labai dažnai (80–99%) | 1 ligoje |
| PEX11Bperoxisomal biogenesis factor 11 beta | Labai dažnai (80–99%) | 1 ligoje |
| PEX12peroxisomal biogenesis factor 12 | Labai dažnai (80–99%) | 1 ligoje |
| PEX13peroxisomal biogenesis factor 13 | Labai dažnai (80–99%) | 1 ligoje |
| PEX14peroxisomal biogenesis factor 14 | Labai dažnai (80–99%) | 1 ligoje |
| PEX16peroxisomal biogenesis factor 16 | Labai dažnai (80–99%) | 1 ligoje |
| PEX2peroxisomal biogenesis factor 2 | Labai dažnai (80–99%) | 1 ligoje |
| PEX26peroxisomal biogenesis factor 26 | Labai dažnai (80–99%) | 1 ligoje |
| PEX3peroxisomal biogenesis factor 3 | Labai dažnai (80–99%) | 1 ligoje |
| PEX5peroxisomal biogenesis factor 5 | Labai dažnai (80–99%) | 1 ligoje |
| PEX6peroxisomal biogenesis factor 6 | Labai dažnai (80–99%) | 1 ligoje |
| SMPD1sphingomyelin phosphodiesterase 1 | Labai dažnai (80–99%) | 2 ligose |
| ACTG2actin gamma 2, smooth muscle | Dažnai (30–79%) | 1 ligoje |
| AKR1D1aldo-keto reductase family 1 member D1 | Dažnai (30–79%) | 2 ligose |
Rodyti dar 101 geną
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| COX16cytochrome c oxidase assembly factor COX16 | Dažnai (30–79%) | 1 ligoje |
| CPT2carnitine palmitoyltransferase 2 | Dažnai (30–79%) | 2 ligose |
| DEF6DEF6 guanine nucleotide exchange factor | Dažnai (30–79%) | 1 ligoje |
| FOCADfocadhesin | Dažnai (30–79%) | 1 ligoje |
| GALTgalactose-1-phosphate uridylyltransferase | Dažnai (30–79%) | 1 ligoje |
| GFM1G elongation factor mitochondrial 1 | Dažnai (30–79%) | 1 ligoje |
| H4C3H4 clustered histone 3 | Dažnai (30–79%) | 1 ligoje |
| IL12Ainterleukin 12A | Dažnai (30–79%) | 1 ligoje |
| IL12RB1interleukin 12 receptor subunit beta 1 | Dažnai (30–79%) | 1 ligoje |
| IRF5interferon regulatory factor 5 | Dažnai (30–79%) | 1 ligoje |
| MMEL1membrane metalloendopeptidase like 1 | Dažnai (30–79%) | 1 ligoje |
| MPV17mitochondrial inner membrane protein MPV17 | Dažnai (30–79%) | 1 ligoje |
| MRPS7mitochondrial ribosomal protein S7 | Dažnai (30–79%) | 1 ligoje |
| POLGDNA polymerase gamma, catalytic subunit | Dažnai (30–79%) | 1 ligoje |
| POU2AF1POU class 2 homeobox associating factor 1 | Dažnai (30–79%) | 1 ligoje |
| RBM10RNA binding motif protein 10 | Dažnai (30–79%) | 1 ligoje |
| SC5Dsterol-C5-desaturase | Dažnai (30–79%) | 1 ligoje |
| SERAC1serine active site containing 1 | Dažnai (30–79%) | 1 ligoje |
| SLC7A7solute carrier family 7 member 7 | Dažnai (30–79%) | 1 ligoje |
| SPIBSpi-B transcription factor | Dažnai (30–79%) | 1 ligoje |
| TJP2tight junction protein 2 | Dažnai (30–79%) | 1 ligoje |
| TNFSF15TNF superfamily member 15 | Dažnai (30–79%) | 1 ligoje |
| TNPO3transportin 3 | Dažnai (30–79%) | 1 ligoje |
| VMA22vacuolar ATPase assembly factor VMA22 | Dažnai (30–79%) | 1 ligoje |
| ACDACD shelterin complex subunit and telomerase recruitment factor | Kartais (5–29%) | 1 ligoje |
| ACVRL1activin A receptor like type 1 | Kartais (5–29%) | 1 ligoje |
| ALMS1ALMS1 centrosome and basal body associated protein | Kartais (5–29%) | 1 ligoje |
| ASLargininosuccinate lyase | Kartais (5–29%) | 1 ligoje |
| BAATbile acid-CoA:amino acid N-acyltransferase | Kartais (5–29%) | 1 ligoje |
| BTNL2butyrophilin like 2 | Kartais (5–29%) | 1 ligoje |
| CILK1ciliogenesis associated kinase 1 | Kartais (5–29%) | 1 ligoje |
| CLDN1claudin 1 | Kartais (5–29%) | 1 ligoje |
| COG4component of oligomeric golgi complex 4 | Kartais (5–29%) | 1 ligoje |
| CTC1CST telomere replication complex component 1 | Kartais (5–29%) | 1 ligoje |
| DKC1dyskerin pseudouridine synthase 1 | Kartais (5–29%) | 1 ligoje |
| DLDdihydrolipoamide dehydrogenase | Kartais (5–29%) | 1 ligoje |
| ENGendoglin | Kartais (5–29%) | 1 ligoje |
| EPM2AEPM2A glucan phosphatase, laforin | Kartais (5–29%) | 2 ligose |
| GDF2growth differentiation factor 2 | Kartais (5–29%) | 1 ligoje |
| HLA-Bmajor histocompatibility complex, class I, B | Kartais (5–29%) | 1 ligoje |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Kartais (5–29%) | 2 ligose |
| IARS1isoleucyl-tRNA synthetase 1 | Kartais (5–29%) | 1 ligoje |
| IARS2isoleucyl-tRNA synthetase 2, mitochondrial | Kartais (5–29%) | 1 ligoje |
| IL21Rinterleukin 21 receptor | Kartais (5–29%) | 1 ligoje |
| JAG1jagged canonical Notch ligand 1 | Kartais (5–29%) | 1 ligoje |
| MED12mediator complex subunit 12 | Kartais (5–29%) | 1 ligoje |
| MT-ATP6mitochondrially encoded ATP synthase membrane subunit 6 | Kartais (5–29%) | 1 ligoje |
| MT-ND1mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 | Kartais (5–29%) | 1 ligoje |
| MT-ND2mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 | Kartais (5–29%) | 1 ligoje |
| MT-ND3mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 3 | Kartais (5–29%) | 1 ligoje |
| MT-ND4mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4 | Kartais (5–29%) | 1 ligoje |
| MT-ND5mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 | Kartais (5–29%) | 1 ligoje |
| MT-ND6mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 | Kartais (5–29%) | 1 ligoje |
| MT-TKmitochondrially encoded tRNA-Lys (AAA/G) | Kartais (5–29%) | 1 ligoje |
| MT-TL1mitochondrially encoded tRNA-Leu (UUA/G) 1 | Kartais (5–29%) | 1 ligoje |
| MT-TVmitochondrially encoded tRNA-Val (GUN) | Kartais (5–29%) | 1 ligoje |
| MT-TWmitochondrially encoded tRNA-Trp (UGA/G) | Kartais (5–29%) | 1 ligoje |
| NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1 | Kartais (5–29%) | 1 ligoje |
| NHP2NHP2 ribonucleoprotein | Kartais (5–29%) | 1 ligoje |
| NOP10NOP10 ribonucleoprotein | Kartais (5–29%) | 1 ligoje |
| NPM1nucleophosmin 1 | Kartais (5–29%) | 1 ligoje |
| P4HA2prolyl 4-hydroxylase subunit alpha 2 | Kartais (5–29%) | 1 ligoje |
| PARNpoly(A)-specific ribonuclease | Kartais (5–29%) | 1 ligoje |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Kartais (5–29%) | 1 ligoje |
| RTEL1regulator of telomere elongation helicase 1 | Kartais (5–29%) | 1 ligoje |
| SH2D1ASH2 domain containing 1A | Kartais (5–29%) | 1 ligoje |
| SLC25A20solute carrier family 25 member 20 | Kartais (5–29%) | 1 ligoje |
| SLC2A2solute carrier family 2 member 2 | Kartais (5–29%) | 1 ligoje |
| SMAD4SMAD family member 4 | Kartais (5–29%) | 1 ligoje |
| TERCtelomerase RNA component | Kartais (5–29%) | 1 ligoje |
| TERTtelomerase reverse transcriptase | Kartais (5–29%) | 1 ligoje |
| TINF2TERF1 interacting nuclear factor 2 | Kartais (5–29%) | 1 ligoje |
| TYMSthymidylate synthetase | Kartais (5–29%) | 1 ligoje |
| USB1U6 snRNA biogenesis phosphodiesterase 1 | Kartais (5–29%) | 1 ligoje |
| WRAP53WD repeat containing antisense to TP53 | Kartais (5–29%) | 1 ligoje |
| XIAPX-linked inhibitor of apoptosis | Kartais (5–29%) | 2 ligose |
| ASAH1N-acylsphingosine amidohydrolase 1 | Retai (1–4 %) | 1 ligoje |
| ATRXATRX chromatin remodeler | Retai (1–4 %) | 1 ligoje |
| F13A1coagulation factor XIII A chain | Retai (1–4 %) | 1 ligoje |
| F13Bcoagulation factor XIII B chain | Retai (1–4 %) | 1 ligoje |
| GBA1glucosylceramidase beta 1 | Retai (1–4 %) | 2 ligose |
| MAP2K1mitogen-activated protein kinase kinase 1 | Retai (1–4 %) | 1 ligoje |
| NRASNRAS proto-oncogene, GTPase | Retai (1–4 %) | 1 ligoje |
| RYR1ryanodine receptor 1 | Retai (1–4 %) | 1 ligoje |
| SCARB2scavenger receptor class B member 2 | Retai (1–4 %) | 1 ligoje |
| SLC25A15solute carrier family 25 member 15 | Retai (1–4 %) | 1 ligoje |
| ACAD9acyl-CoA dehydrogenase family member 9 | Neužfiksuota | 1 ligoje |
| AMACRalpha-methylacyl-CoA racemase | Neužfiksuota | 1 ligoje |
| APTXaprataxin | Neužfiksuota | 1 ligoje |
| COQ2coenzyme Q2, polyprenyltransferase | Neužfiksuota | 1 ligoje |
| FECHferrochelatase | Neužfiksuota | 1 ligoje |
| GBE11,4-alpha-glucan branching enzyme 1 | Neužfiksuota | 1 ligoje |
| HSD3B7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | Neužfiksuota | 1 ligoje |
| IFT122intraflagellar transport 122 | Neužfiksuota | 1 ligoje |
| IFT172intraflagellar transport 172 | Neužfiksuota | 1 ligoje |
| MPImannose phosphate isomerase | Neužfiksuota | 1 ligoje |
| NDUFS4NADH:ubiquinone oxidoreductase subunit S4 | Neužfiksuota | 1 ligoje |
| OSTM1osteoclastogenesis associated transmembrane protein 1 | Neužfiksuota | 1 ligoje |
| PCK2phosphoenolpyruvate carboxykinase 2, mitochondrial | Neužfiksuota | 1 ligoje |
| SCYL1SCY1 like pseudokinase 1 | Neužfiksuota | 1 ligoje |
| SKIC3SKI3 subunit of superkiller complex | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
Siauresni požymiai
Platesni požymiai
Iš kur tai žinoma
- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.17-8666dff2.
AtlasKam padedameMūsų mokslasProduktaiRezultatai
PrisijungtiKlaustiSekvenuokite savo genomą↗
Vienas testas. Atsakymai visam gyvenimui.
Nuo 449 $Nemokamas pristatymas · Rezultatai per 6–8 savaites