Požymis
Infection in blood stream
Klinikinis pavadinimas: Sepsis
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection.
Santrauka
- Kūno sistema
- Abnormality of the immune system
Atskaitos genomasGRCh38hg38
Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.
Read the genes linked to Infection in blood stream, and the rest of your genome, with one test.
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Įsigyti savo Genome Test135 genų susiję su Infection in blood stream
Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Infection in blood stream. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| COPZ1coat protein complex I subunit zeta 1 | Visada | 1 ligoje |
| COX8Acytochrome c oxidase subunit 8A | Visada | 1 ligoje |
| DCLRE1CDNA cross-link repair 1C | Visada | 3 ligose |
| DEPDC5DEP domain containing 5, GATOR1 subcomplex subunit | Visada | 1 ligoje |
| EXTL3exostosin like glycosyltransferase 3 | Visada | 1 ligoje |
| HMOX1heme oxygenase 1 | Visada | 1 ligoje |
| HYOU1hypoxia up-regulated 1 | Visada | 1 ligoje |
| KRT5keratin 5 | Visada | 2 ligose |
| LMOD1leiomodin 1 | Visada | 2 ligose |
| LRBALPS responsive beige-like anchor protein | Visada | 1 ligoje |
| MRTFAmyocardin related transcription factor A | Visada | 1 ligoje |
| NEUROG3neurogenin 3 | Visada | 1 ligoje |
| NOTCH3notch receptor 3 | Visada | 1 ligoje |
| PEX1peroxisomal biogenesis factor 1 | Visada | 1 ligoje |
| PEX19peroxisomal biogenesis factor 19 | Visada | 1 ligoje |
| RAG1recombination activating 1 | Visada | 3 ligose |
| RAG2recombination activating 2 | Visada | 2 ligose |
| RFXANKregulatory factor X associated ankyrin containing protein | Visada | 1 ligoje |
| RNU6ATACRNA, U6atac small nuclear | Visada | 1 ligoje |
| SEC61A1SEC61 translocon subunit alpha 1 | Visada | 2 ligose |
| SEL1LSEL1L adaptor subunit of SYVN1 ubiquitin ligase | Visada | 1 ligoje |
| SMARCD2SWI/SNF related BAF chromatin remodeling complex subunit D2 | Visada | 1 ligoje |
| STIM1stromal interaction molecule 1 | Visada | 1 ligoje |
| AK2adenylate kinase 2 | Labai dažnai (80–99%) | 2 ligose |
| BTKBruton tyrosine kinase | Labai dažnai (80–99%) | 2 ligose |
| C1QBcomplement C1q B chain | Dažnai (30–79%) | 1 ligoje |
| DEF6DEF6 guanine nucleotide exchange factor | Dažnai (30–79%) | 1 ligoje |
| IL2RGinterleukin 2 receptor subunit gamma | Dažnai (30–79%) | 2 ligose |
| PGM3phosphoglucomutase 3 | Dažnai (30–79%) | 1 ligoje |
| RAC2Rac family small GTPase 2 | Dažnai (30–79%) | 1 ligoje |
| RFX5regulatory factor X5 | Dažnai (30–79%) | 1 ligoje |
| SASH3SAM and SH3 domain containing 3 | Dažnai (30–79%) | 1 ligoje |
| SPINK5serine peptidase inhibitor Kazal type 5 | Dažnai (30–79%) | 1 ligoje |
| STK4serine/threonine kinase 4 | Dažnai (30–79%) | 1 ligoje |
| TFRCtransferrin receptor | Dažnai (30–79%) | 1 ligoje |
| YARS1tyrosyl-tRNA synthetase 1 | Dažnai (30–79%) | 1 ligoje |
| ABCD1ATP binding cassette subfamily D member 1 | Kartais (5–29%) | 1 ligoje |
| ACTG2actin gamma 2, smooth muscle | Kartais (5–29%) | 1 ligoje |
| ADAadenosine deaminase | Kartais (5–29%) | 1 ligoje |
| AIREautoimmune regulator | Kartais (5–29%) | 1 ligoje |
Rodyti dar 95 genų
| Genas | Kaip dažnai pasireiškia | Ligos |
|---|---|---|
| ALG1ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase | Kartais (5–29%) | 1 ligoje |
| APCAPC regulator of Wnt signaling pathway | Kartais (5–29%) | 1 ligoje |
| ATP7AATPase copper transporting alpha | Kartais (5–29%) | 2 ligose |
| BLNKB cell linker | Kartais (5–29%) | 1 ligoje |
| CD27CD27 molecule | Kartais (5–29%) | 1 ligoje |
| CD40LGCD40 ligand | Kartais (5–29%) | 1 ligoje |
| CD79ACD79a molecule | Kartais (5–29%) | 1 ligoje |
| CD79BCD79b molecule | Kartais (5–29%) | 1 ligoje |
| CHD7chromodomain helicase DNA binding protein 7 | Kartais (5–29%) | 1 ligoje |
| CTCFCCCTC-binding factor | Kartais (5–29%) | 1 ligoje |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Kartais (5–29%) | 2 ligose |
| CTNNB1catenin beta 1 | Kartais (5–29%) | 1 ligoje |
| CYBAcytochrome b-245 alpha chain | Kartais (5–29%) | 1 ligoje |
| CYBBcytochrome b-245 beta chain | Kartais (5–29%) | 1 ligoje |
| CYBC1cytochrome b-245 chaperone 1 | Kartais (5–29%) | 1 ligoje |
| DOCK8dedicator of cytokinesis 8 | Kartais (5–29%) | 1 ligoje |
| ECE1endothelin converting enzyme 1 | Kartais (5–29%) | 1 ligoje |
| EDN3endothelin 3 | Kartais (5–29%) | 1 ligoje |
| EDNRBendothelin receptor type B | Kartais (5–29%) | 1 ligoje |
| ERBB2erb-b2 receptor tyrosine kinase 2 | Kartais (5–29%) | 1 ligoje |
| ERBB3erb-b2 receptor tyrosine kinase 3 | Kartais (5–29%) | 1 ligoje |
| FBXO22F-box protein 22 | Kartais (5–29%) | 1 ligoje |
| FCGR3BFc gamma receptor IIIb | Kartais (5–29%) | 1 ligoje |
| FOCADfocadhesin | Kartais (5–29%) | 1 ligoje |
| FOXN1forkhead box N1 | Kartais (5–29%) | 1 ligoje |
| G6PC3glucose-6-phosphatase catalytic subunit 3 | Kartais (5–29%) | 1 ligoje |
| GALTgalactose-1-phosphate uridylyltransferase | Kartais (5–29%) | 1 ligoje |
| GDNFglial cell derived neurotrophic factor | Kartais (5–29%) | 1 ligoje |
| HLA-Bmajor histocompatibility complex, class I, B | Kartais (5–29%) | 1 ligoje |
| IDH1isocitrate dehydrogenase (NADP(+)) 1 | Kartais (5–29%) | 1 ligoje |
| IGHMimmunoglobulin heavy constant mu | Kartais (5–29%) | 1 ligoje |
| IGLL1immunoglobulin lambda like polypeptide 1 | Kartais (5–29%) | 1 ligoje |
| IKZF1IKAROS family zinc finger 1 | Kartais (5–29%) | 1 ligoje |
| IL7Rinterleukin 7 receptor | Kartais (5–29%) | 1 ligoje |
| KRT14keratin 14 | Kartais (5–29%) | 1 ligoje |
| LAMA3laminin subunit alpha 3 | Kartais (5–29%) | 1 ligoje |
| LAMB3laminin subunit beta 3 | Kartais (5–29%) | 1 ligoje |
| LAMC2laminin subunit gamma 2 | Kartais (5–29%) | 1 ligoje |
| LRRC8Aleucine rich repeat containing 8 VRAC subunit A | Kartais (5–29%) | 1 ligoje |
| MMUTmethylmalonyl-CoA mutase | Kartais (5–29%) | 1 ligoje |
| MYD88MYD88 innate immune signal transduction adaptor | Kartais (5–29%) | 1 ligoje |
| MYH11myosin heavy chain 11 | Kartais (5–29%) | 1 ligoje |
| MYLKmyosin light chain kinase | Kartais (5–29%) | 1 ligoje |
| NCF1neutrophil cytosolic factor 1 | Kartais (5–29%) | 1 ligoje |
| NCF2neutrophil cytosolic factor 2 | Kartais (5–29%) | 1 ligoje |
| NCF4neutrophil cytosolic factor 4 | Kartais (5–29%) | 1 ligoje |
| NFKB2nuclear factor kappa B subunit 2 | Kartais (5–29%) | 1 ligoje |
| NRTNneurturin | Kartais (5–29%) | 1 ligoje |
| NUDCD3NudC domain containing 3 | Kartais (5–29%) | 1 ligoje |
| PIK3CDphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Kartais (5–29%) | 1 ligoje |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Kartais (5–29%) | 1 ligoje |
| PKP1plakophilin 1 | Kartais (5–29%) | 1 ligoje |
| PSMB10proteasome 20S subunit beta 10 | Kartais (5–29%) | 1 ligoje |
| RETret proto-oncogene | Kartais (5–29%) | 1 ligoje |
| RMRPRNA component of mitochondrial RNA processing endoribonuclease | Kartais (5–29%) | 1 ligoje |
| RNF13ring finger protein 13 | Kartais (5–29%) | 1 ligoje |
| SAMD9sterile alpha motif domain containing 9 | Kartais (5–29%) | 1 ligoje |
| SEMA3Csemaphorin 3C | Kartais (5–29%) | 1 ligoje |
| SEMA3Dsemaphorin 3D | Kartais (5–29%) | 1 ligoje |
| SMOsmoothened, frizzled class receptor | Kartais (5–29%) | 1 ligoje |
| SPI1Spi-1 proto-oncogene | Kartais (5–29%) | 1 ligoje |
| SREBF1sterol regulatory element binding transcription factor 1 | Kartais (5–29%) | 1 ligoje |
| TCF3transcription factor 3 | Kartais (5–29%) | 1 ligoje |
| TREX1three prime repair exonuclease 1 | Kartais (5–29%) | 1 ligoje |
| VPS33AVPS33A core subunit of CORVET and HOPS complexes | Kartais (5–29%) | 2 ligose |
| WASWASP actin nucleation promoting factor | Kartais (5–29%) | 2 ligose |
| ABCA12ATP binding cassette subfamily A member 12 | Retai (1–4 %) | 1 ligoje |
| ABCA3ATP binding cassette subfamily A member 3 | Retai (1–4 %) | 1 ligoje |
| ALG12ALG12 alpha-1,6-mannosyltransferase | Retai (1–4 %) | 1 ligoje |
| ALOX12Barachidonate 12-lipoxygenase, 12R type | Retai (1–4 %) | 1 ligoje |
| ALOXE3arachidonate epidermal lipoxygenase 3 | Retai (1–4 %) | 1 ligoje |
| AP1S3adaptor related protein complex 1 subunit sigma 3 | Retai (1–4 %) | 1 ligoje |
| ASPRV1aspartic peptidase retroviral like 1 | Retai (1–4 %) | 1 ligoje |
| CXCR4C-X-C motif chemokine receptor 4 | Retai (1–4 %) | 1 ligoje |
| CYP4F22cytochrome P450 family 4 subfamily F member 22 | Retai (1–4 %) | 1 ligoje |
| DNAJC21DnaJ heat shock protein family (Hsp40) member C21 | Retai (1–4 %) | 1 ligoje |
| EFL1elongation factor like GTPase 1 | Retai (1–4 %) | 1 ligoje |
| ELANEelastase, neutrophil expressed | Retai (1–4 %) | 1 ligoje |
| FOXP3forkhead box P3 | Retai (1–4 %) | 1 ligoje |
| GALMgalactose mutarotase | Retai (1–4 %) | 1 ligoje |
| GJB2gap junction protein beta 2 | Retai (1–4 %) | 1 ligoje |
| GJB6gap junction protein beta 6 | Retai (1–4 %) | 1 ligoje |
| IGHG2immunoglobulin heavy constant gamma 2 (G2m marker) | Retai (1–4 %) | 1 ligoje |
| IGKCimmunoglobulin kappa constant | Retai (1–4 %) | 1 ligoje |
| IL36RNinterleukin 36 receptor antagonist | Retai (1–4 %) | 1 ligoje |
| LIPNlipase family member N | Retai (1–4 %) | 1 ligoje |
| NIPAL4NIPA like domain containing 4 | Retai (1–4 %) | 1 ligoje |
| SBDSSBDS ribosome maturation factor | Retai (1–4 %) | 1 ligoje |
| SDR9C7short chain dehydrogenase/reductase family 9C member 7 | Retai (1–4 %) | 1 ligoje |
| SFTPBsurfactant protein B | Retai (1–4 %) | 1 ligoje |
| SFTPCsurfactant protein C | Retai (1–4 %) | 1 ligoje |
| SULT2B1sulfotransferase family 2B member 1 | Retai (1–4 %) | 1 ligoje |
| TGM1transglutaminase 1 | Retai (1–4 %) | 1 ligoje |
| FERMT3FERM domain containing kindlin 3 | Neužfiksuota | 1 ligoje |
| MNX1motor neuron and pancreas homeobox 1 | Neužfiksuota | 1 ligoje |
Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.
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- Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
- Duomenų leidimas 2026.10.16-c6eea6bf.
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