Tunnus
Fused toes
Kliiniline nimetus: Toe syndactyly
Webbing or fusion of the toes, involving soft parts only or including bone structure. Bony fusions are referred to as "bony" Syndactyly if the fusion occurs in a radio-ulnar axis. Fusions of bones of the toes in a proximo-distal axis are referred to as "Symphalangism".
Kokkuvõte
- Teised nimetused
- Webbed toes, Foot syndactyly, Syndactyly of feet, Syndactyly of toes
VõrdlusgenoomGRCh38hg38
Geeni- ja variandilehtede positsioonid järgivad seda valikut selles brauseris.
Read the genes linked to Fused toes, and the rest of your genome, with one test.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast
Telli oma Genome Test137 geeni on seotud tunnusega Fused toes
Nende geenide muutused põhjustavad haruldasi haigusi, mille puhul esineb Fused toes. Enamikul selle tunnusega inimestest ei ole ühtegi neist haigustest. Selles loendis olev geen ei ütle midagi kellegi enda genoomi kohta.
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| CCNQcyclin Q | Alati | Esineb 2 haiguses |
| DONSONDNA replication fork stabilization factor DONSON | Alati | Esineb 1 haiguses |
| EN1engrailed homeobox 1 | Alati | Esineb 1 haiguses |
| MEGF8multiple EGF like domains 8 | Alati | Esineb 1 haiguses |
| MRPS28mitochondrial ribosomal protein S28 | Alati | Esineb 1 haiguses |
| POLR3GLRNA polymerase III subunit GL | Alati | Esineb 1 haiguses |
| PUM1pumilio RNA binding family member 1 | Alati | Esineb 1 haiguses |
| RAB23RAB23, member RAS oncogene family | Alati | Esineb 2 haiguses |
| SCNM1sodium channel modifier 1 | Alati | Esineb 1 haiguses |
| BHLHA9basic helix-loop-helix family member a9 | Väga sageli (80–99%) | Esineb 1 haiguses |
| BRD4bromodomain containing 4 | Väga sageli (80–99%) | Esineb 1 haiguses |
| FGFR2fibroblast growth factor receptor 2 | Väga sageli (80–99%) | Esineb 8 haiguses |
| GJA1gap junction protein alpha 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| HDAC8histone deacetylase 8 | Väga sageli (80–99%) | Esineb 2 haiguses |
| HOXD13homeobox D13 | Väga sageli (80–99%) | Esineb 1 haiguses |
| IRF6interferon regulatory factor 6 | Väga sageli (80–99%) | Esineb 1 haiguses |
| LMBR1limb development membrane protein 1 | Väga sageli (80–99%) | Esineb 2 haiguses |
| MAU2MAU2 sister chromatid cohesion factor | Väga sageli (80–99%) | Esineb 1 haiguses |
| MYCNMYCN proto-oncogene, bHLH transcription factor | Väga sageli (80–99%) | Esineb 1 haiguses |
| NECTIN1nectin cell adhesion molecule 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| NIPBLNIPBL cohesin loading factor | Väga sageli (80–99%) | Esineb 2 haiguses |
| NR4A2nuclear receptor subfamily 4 group A member 2 | Väga sageli (80–99%) | Esineb 1 haiguses |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Väga sageli (80–99%) | Esineb 1 haiguses |
| RAD21RAD21 cohesin complex component | Väga sageli (80–99%) | Esineb 1 haiguses |
| RIPK4receptor interacting serine/threonine kinase 4 | Väga sageli (80–99%) | Esineb 1 haiguses |
| SMC1Astructural maintenance of chromosomes 1A | Väga sageli (80–99%) | Esineb 1 haiguses |
| SMC3structural maintenance of chromosomes 3 | Väga sageli (80–99%) | Esineb 2 haiguses |
| SMOC1SPARC related modular calcium binding 1 | Väga sageli (80–99%) | Esineb 2 haiguses |
| TBR1T-box brain transcription factor 1 | Väga sageli (80–99%) | Esineb 1 haiguses |
| TP63tumor protein p63 | Väga sageli (80–99%) | Esineb 5 haiguses |
| APCAPC regulator of Wnt signaling pathway | Sageli (30–79%) | Esineb 1 haiguses |
| B3GLCTbeta 3-glucosyltransferase | Sageli (30–79%) | Esineb 1 haiguses |
| CPLANE1ciliogenesis and planar polarity effector complex subunit 1 | Sageli (30–79%) | Esineb 1 haiguses |
| ESCO2establishment of sister chromatid cohesion N-acetyltransferase 2 | Sageli (30–79%) | Esineb 1 haiguses |
| FGFR1fibroblast growth factor receptor 1 | Sageli (30–79%) | Esineb 1 haiguses |
| FLI1Fli-1 proto-oncogene, ETS transcription factor | Sageli (30–79%) | Esineb 1 haiguses |
| FRAS1Fraser extracellular matrix complex subunit 1 | Sageli (30–79%) | Esineb 1 haiguses |
| FREM2FRAS1 related extracellular matrix 2 | Sageli (30–79%) | Esineb 1 haiguses |
| GLI3GLI family zinc finger 3 | Sageli (30–79%) | Esineb 3 haiguses |
| GPC3glypican 3 | Sageli (30–79%) | Esineb 1 haiguses |
Näita veel 97 geeni
| Geen | Kui sageli seda täheldatakse | Haigused |
|---|---|---|
| GPC4glypican 4 | Sageli (30–79%) | Esineb 1 haiguses |
| GRIP1glutamate receptor interacting protein 1 | Sageli (30–79%) | Esineb 1 haiguses |
| HDAC4histone deacetylase 4 | Sageli (30–79%) | Esineb 1 haiguses |
| IQSEC2IQ motif and Sec7 domain ArfGEF 2 | Sageli (30–79%) | Esineb 1 haiguses |
| KIF7kinesin family member 7 | Sageli (30–79%) | Esineb 1 haiguses |
| LRP4LDL receptor related protein 4 | Sageli (30–79%) | Esineb 1 haiguses |
| MIR17HGmiR-17-92a-1 cluster host gene | Sageli (30–79%) | Esineb 1 haiguses |
| NOGnoggin | Sageli (30–79%) | Esineb 1 haiguses |
| PIGYphosphatidylinositol glycan anchor biosynthesis class Y | Sageli (30–79%) | Esineb 1 haiguses |
| PSAT1phosphoserine aminotransferase 1 | Sageli (30–79%) | Esineb 1 haiguses |
| RAI1retinoic acid induced 1 | Sageli (30–79%) | Esineb 1 haiguses |
| SC5Dsterol-C5-desaturase | Sageli (30–79%) | Esineb 1 haiguses |
| SHHsonic hedgehog signaling molecule | Sageli (30–79%) | Esineb 1 haiguses |
| SMAD2SMAD family member 2 | Sageli (30–79%) | Esineb 1 haiguses |
| SMOsmoothened, frizzled class receptor | Sageli (30–79%) | Esineb 2 haiguses |
| TSHZ3teashirt zinc finger homeobox 3 | Sageli (30–79%) | Esineb 1 haiguses |
| WLSWnt ligand secretion mediator | Sageli (30–79%) | Esineb 1 haiguses |
| WNT7AWnt family member 7A | Sageli (30–79%) | Esineb 1 haiguses |
| ARL6IP6ARF like GTPase 6 interacting protein 6 | Mõnikord (5–29%) | Esineb 1 haiguses |
| BCRBCR activator of RhoGEF and GTPase | Mõnikord (5–29%) | Esineb 1 haiguses |
| BMS1BMS1 ribosome biogenesis factor | Mõnikord (5–29%) | Esineb 1 haiguses |
| BRCA1BRCA1 DNA repair associated | Mõnikord (5–29%) | Esineb 1 haiguses |
| BRCA2BRCA2 DNA repair associated | Mõnikord (5–29%) | Esineb 1 haiguses |
| BRIP1BRCA1 interacting DNA helicase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| CD96CD96 molecule | Mõnikord (5–29%) | Esineb 2 haiguses |
| CEP120centrosomal protein 120 | Mõnikord (5–29%) | Esineb 1 haiguses |
| CRKLCRK like proto-oncogene, adaptor protein | Mõnikord (5–29%) | Esineb 1 haiguses |
| CUL4Bcullin 4B | Mõnikord (5–29%) | Esineb 1 haiguses |
| DACT1dishevelled binding antagonist of beta catenin 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| DLL4delta like canonical Notch ligand 4 | Mõnikord (5–29%) | Esineb 1 haiguses |
| DYNC2H1dynein cytoplasmic 2 heavy chain 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| DYNC2I1dynein 2 intermediate chain 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| DYNC2I2dynein 2 intermediate chain 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| DYNC2LI1dynein cytoplasmic 2 light intermediate chain 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Mõnikord (5–29%) | Esineb 1 haiguses |
| FAAP100FA core complex associated protein 100 | Mõnikord (5–29%) | Esineb 1 haiguses |
| FANCAFA complementation group A | Mõnikord (5–29%) | Esineb 1 haiguses |
| FANCBFA complementation group B | Mõnikord (5–29%) | Esineb 1 haiguses |
| FANCCFA complementation group C | Mõnikord (5–29%) | Esineb 1 haiguses |
| FANCD2FA complementation group D2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| FANCEFA complementation group E | Mõnikord (5–29%) | Esineb 1 haiguses |
| FANCFFA complementation group F | Mõnikord (5–29%) | Esineb 1 haiguses |
| FANCGFA complementation group G | Mõnikord (5–29%) | Esineb 1 haiguses |
| FANCIFA complementation group I | Mõnikord (5–29%) | Esineb 1 haiguses |
| FANCLFA complementation group L | Mõnikord (5–29%) | Esineb 1 haiguses |
| FANCMFA complementation group M | Mõnikord (5–29%) | Esineb 1 haiguses |
| FBXO11F-box protein 11 | Mõnikord (5–29%) | Esineb 1 haiguses |
| FGF10fibroblast growth factor 10 | Mõnikord (5–29%) | Esineb 1 haiguses |
| FGFR3fibroblast growth factor receptor 3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| GNA11G protein subunit alpha 11 | Mõnikord (5–29%) | Esineb 1 haiguses |
| H3-3AH3.3 histone A | Mõnikord (5–29%) | Esineb 1 haiguses |
| IFT140intraflagellar transport 140 | Mõnikord (5–29%) | Esineb 1 haiguses |
| IFT172intraflagellar transport 172 | Mõnikord (5–29%) | Esineb 1 haiguses |
| IFT80intraflagellar transport 80 | Mõnikord (5–29%) | Esineb 1 haiguses |
| ITGB4integrin subunit beta 4 | Mõnikord (5–29%) | Esineb 1 haiguses |
| KIAA0753KIAA0753 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MAD2L2mitotic arrest deficient 2 like 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MAPK1mitogen-activated protein kinase 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| MEF2Cmyocyte enhancer factor 2C | Mõnikord (5–29%) | Esineb 1 haiguses |
| NEK9NIMA related kinase 9 | Mõnikord (5–29%) | Esineb 1 haiguses |
| NXNnucleoredoxin | Mõnikord (5–29%) | Esineb 1 haiguses |
| OTUD6BOTU deubiquitinase 6B | Mõnikord (5–29%) | Esineb 1 haiguses |
| PALB2partner and localizer of BRCA2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| PLECplectin | Mõnikord (5–29%) | Esineb 1 haiguses |
| RAD51RAD51 recombinase | Mõnikord (5–29%) | Esineb 1 haiguses |
| RAD51CRAD51 paralog C | Mõnikord (5–29%) | Esineb 1 haiguses |
| RFWD3ring finger and WD repeat domain 3 | Mõnikord (5–29%) | Esineb 1 haiguses |
| ROR2ROR family WNT receptor 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| RPL10ribosomal protein L10 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SALL1spalt like transcription factor 1 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SALL4spalt like transcription factor 4 | Mõnikord (5–29%) | Esineb 1 haiguses |
| SIN3ASIN3 transcription regulator family member A | Mõnikord (5–29%) | Esineb 1 haiguses |
| SLX4SLX4 structure-specific endonuclease subunit | Mõnikord (5–29%) | Esineb 1 haiguses |
| TBX22T-box transcription factor 22 | Mõnikord (5–29%) | Esineb 1 haiguses |
| TFAP2Btranscription factor AP-2 beta | Mõnikord (5–29%) | Esineb 1 haiguses |
| TTC21Btetratricopeptide repeat domain 21B | Mõnikord (5–29%) | Esineb 1 haiguses |
| TWIST2twist family bHLH transcription factor 2 | Mõnikord (5–29%) | Esineb 2 haiguses |
| UBA2ubiquitin like modifier activating enzyme 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| UBE2Tubiquitin conjugating enzyme E2 T | Mõnikord (5–29%) | Esineb 1 haiguses |
| WDR19WD repeat domain 19 | Mõnikord (5–29%) | Esineb 1 haiguses |
| XRCC2X-ray repair cross complementing 2 | Mõnikord (5–29%) | Esineb 1 haiguses |
| ZNF699zinc finger protein 699 | Mõnikord (5–29%) | Esineb 1 haiguses |
| CTCFCCCTC-binding factor | Harva (1–4%) | Esineb 1 haiguses |
| ARHGAP31Rho GTPase activating protein 31 | Pole registreeritud | Esineb 1 haiguses |
| ATP6V1B2ATPase H+ transporting V1 subunit B2 | Pole registreeritud | Esineb 1 haiguses |
| BMP4bone morphogenetic protein 4 | Pole registreeritud | Esineb 1 haiguses |
| EFNB1ephrin B1 | Pole registreeritud | Esineb 1 haiguses |
| FIG4FIG4 phosphoinositide 5-phosphatase | Pole registreeritud | Esineb 1 haiguses |
| FLNAfilamin A | Pole registreeritud | Esineb 2 haiguses |
| KCNJ2potassium inwardly rectifying channel subfamily J member 2 | Pole registreeritud | Esineb 1 haiguses |
| PHGDHphosphoglycerate dehydrogenase | Pole registreeritud | Esineb 1 haiguses |
| PORCNporcupine O-acyltransferase | Pole registreeritud | Esineb 1 haiguses |
| SF3B4splicing factor 3b subunit 4 | Pole registreeritud | Esineb 1 haiguses |
| TBC1D32TBC1 domain family member 32 | Pole registreeritud | Esineb 1 haiguses |
| TCTN3tectonic family member 3 | Pole registreeritud | Esineb 1 haiguses |
| TWIST1twist family bHLH transcription factor 1 | Pole registreeritud | Esineb 1 haiguses |
| WNT10BWnt family member 10B | Pole registreeritud | Esineb 1 haiguses |
Kui sageli see esineb geenist tulenevate seisunditega inimeste seas, kõige sagedamini nende kõigi seas, nagu on märgitud Inimese fenotüübi ontoloogias. Need lehed kirjeldavad tunnuseid ja nende taga olevaid uuringuid; need ei ole diagnoos ning sümptomite kohta tuleks küsida arstilt või geneetilt nõustajalt.
Kitsamad tunnused
- Webbed 2nd and 3rd toes97 geeni
- Webbed 4th-5th toes14 geeni
- Webbed skin of toes12 geeni
- Webbed 3rd-4th toes7 geeni
- Webbed 2nd-4th toes5 geeni
- Webbed 2nd-5th toes4 geeni
- Webbed first and second toes4 geeni
- Webbed 1st-3rd toes1 geen
- Webbed 1st-5th toes1 geen
- Webbed 3rd-5th toes1 geen
- Webbed first through fourth toes1 geen
Laiemad tunnused
Allikas
- Inimese fenotüübi ontoloogia, versioon 2026-09-01: tunnus, selle nimetused, määratlus ja sellega seotud geenid. Lisateave leiab aadressilt hpo.jax.org.
- Andmeversioon 2026.10.16-c6eea6bf.
Üks test. Vastused kogu eluks.
Alates 449 $Tasuta kohaletoimetamine · Tulemused 6–8 nädala pärast