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Požymis

Increased plasma triglycerides

Klinikinis pavadinimas: Hypertriglyceridemia

The concentration of triglyceride in the blood circulation is above the upper limit of normal.

HPO HP:0002155

Santrauka

Taip pat vadinama
Increased serum triglycerides, Increased triglycerides, Elevated triglyceride concentration, Elevated triglyceride level, Elevated triglyceride level in blood, Increased circulating Tg levels, Increased plasma Tg levels, Increased triglyceride concentration, Increased triglyceride level, Increased triglyceride level in blood
Kūno sistema
Laboratory abnormality

Atskaitos genomasGRCh38

Pozicijos genų ir variantų puslapiuose rodomos pagal šį pasirinkimą šioje naršyklėje.

131 genas susijęs su Increased plasma triglycerides

Šių genų pakitimai sukelia retas ligas, kuriose pasireiškia Increased plasma triglycerides. Dauguma žmonių, turinčių šį požymį, neturi nė vienos iš tų ligų, o šiame sąraše esantis genas nieko nesako apie kieno nors paties genomą.

GenasKaip dažnai pasireiškiaLigos
ADRA2Aadrenoceptor alpha 2AVisada1 ligoje
AK2adenylate kinase 2Visada1 ligoje
APOC2apolipoprotein C2Visada1 ligoje
CAV1caveolin 1Visada2 ligose
CIDECcell death inducing DFFA like effector cVisada2 ligose
CREB3L3cAMP responsive element binding protein 3 like 3Visada1 ligoje
FARSAphenylalanyl-tRNA synthetase subunit alphaVisada1 ligoje
GPD1glycerol-3-phosphate dehydrogenase 1Visada1 ligoje
GPIHBP1glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1Visada1 ligoje
LDLRAP1low density lipoprotein receptor adaptor protein 1Visada1 ligoje
LIPClipase C, hepatic typeVisada2 ligose
LMF1lipase maturation factor 1Visada1 ligoje
MCM10minichromosome maintenance 10 replication initiation factorVisada1 ligoje
NSMCE2NSE2 SUMO ligase component of SMC5/6 complexVisada2 ligose
PCYT1Aphosphate cytidylyltransferase 1A, cholineVisada1 ligoje
PIK3CGphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gammaVisada1 ligoje
PLIN1perilipin 1Visada2 ligose
PLVAPplasmalemma vesicle associated proteinVisada1 ligoje
PPARGperoxisome proliferator activated receptor gammaVisada2 ligose
RBSNrabenosyn, RAB effectorVisada2 ligose
RC3H1ring finger and CCCH-type domains 1Visada1 ligoje
SLC19A1solute carrier family 19 member 1Visada1 ligoje
STX11syntaxin 11Visada2 ligose
SUPT7LSPT7 like, STAGA complex subunit gammaVisada1 ligoje
WRNWRN RecQ like helicaseVisada1 ligoje
YARS1tyrosyl-tRNA synthetase 1Visada1 ligoje
ABCA1ATP binding cassette subfamily A member 1Labai dažnai (80–99%)2 ligose
AGLamylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferaseLabai dažnai (80–99%)1 ligoje
AKT2AKT serine/threonine kinase 2Labai dažnai (80–99%)1 ligoje
ALMS1ALMS1 centrosome and basal body associated proteinLabai dažnai (80–99%)2 ligose
APOEapolipoprotein ELabai dažnai (80–99%)2 ligose
CYP7A1cytochrome P450 family 7 subfamily A member 1Labai dažnai (80–99%)1 ligoje
LIPElipase E, hormone sensitive typeLabai dažnai (80–99%)1 ligoje
LMNAlamin A/CLabai dažnai (80–99%)8 ligose
PHKBphosphorylase kinase regulatory subunit betaLabai dažnai (80–99%)1 ligoje
SLC25A13solute carrier family 25 member 13Labai dažnai (80–99%)4 ligose
SLC37A4solute carrier family 37 member 4Labai dažnai (80–99%)1 ligoje
SMPD1sphingomyelin phosphodiesterase 1Labai dažnai (80–99%)3 ligose
XIAPX-linked inhibitor of apoptosisLabai dažnai (80–99%)1 ligoje
XRCC4X-ray repair cross complementing 4Labai dažnai (80–99%)1 ligoje
Rodyti dar 91 geną
GenasKaip dažnai pasireiškiaLigos
ABHD5abhydrolase domain containing 5, lysophosphatidic acid acyltransferaseDažnai (30–79%)1 ligoje
ADCY3adenylate cyclase 3Dažnai (30–79%)1 ligoje
ARL6ARF like GTPase 6Dažnai (30–79%)1 ligoje
BBIP1BBSome interacting protein 1Dažnai (30–79%)1 ligoje
BBS1Bardet-Biedl syndrome 1Dažnai (30–79%)1 ligoje
BBS10Bardet-Biedl syndrome 10Dažnai (30–79%)1 ligoje
BBS12Bardet-Biedl syndrome 12Dažnai (30–79%)1 ligoje
BBS2Bardet-Biedl syndrome 2Dažnai (30–79%)1 ligoje
BBS4Bardet-Biedl syndrome 4Dažnai (30–79%)1 ligoje
BBS5Bardet-Biedl syndrome 5Dažnai (30–79%)1 ligoje
BBS7Bardet-Biedl syndrome 7Dažnai (30–79%)1 ligoje
BBS9Bardet-Biedl syndrome 9Dažnai (30–79%)1 ligoje
BSCL2BSCL2 lipid droplet biogenesis associated, seipinDažnai (30–79%)3 ligose
CAVIN1caveolae associated protein 1Dažnai (30–79%)1 ligoje
CELA2Achymotrypsin like elastase 2ADažnai (30–79%)1 ligoje
CEP19centrosomal protein 19Dažnai (30–79%)2 ligose
CEP290centrosomal protein 290Dažnai (30–79%)1 ligoje
CFAP418cilia and flagella associated protein 418Dažnai (30–79%)1 ligoje
DEF6DEF6 guanine nucleotide exchange factorDažnai (30–79%)1 ligoje
EMDemerinDažnai (30–79%)1 ligoje
EXTL3exostosin like glycosyltransferase 3Dažnai (30–79%)1 ligoje
FHL1four and a half LIM domains 1Dažnai (30–79%)1 ligoje
GUK1guanylate kinase 1Dažnai (30–79%)1 ligoje
IFT172intraflagellar transport 172Dažnai (30–79%)1 ligoje
IFT27intraflagellar transport 27Dažnai (30–79%)1 ligoje
IFT74intraflagellar transport 74Dažnai (30–79%)1 ligoje
LEPleptinDažnai (30–79%)1 ligoje
LEPRleptin receptorDažnai (30–79%)1 ligoje
LIPAlipase A, lysosomal acid typeDažnai (30–79%)2 ligose
LZTFL1leucine zipper transcription factor like 1Dažnai (30–79%)1 ligoje
MKKSMKKS centrosomal shuttling proteinDažnai (30–79%)1 ligoje
MKS1MKS transition zone complex subunit 1Dažnai (30–79%)1 ligoje
NPHP1nephrocystin 1Dažnai (30–79%)1 ligoje
PHKA2phosphorylase kinase regulatory subunit alpha 2Dažnai (30–79%)2 ligose
PHKG2phosphorylase kinase catalytic subunit gamma 2Dažnai (30–79%)2 ligose
PIGHphosphatidylinositol glycan anchor biosynthesis class HDažnai (30–79%)1 ligoje
PLAAT3phospholipase A and acyltransferase 3Dažnai (30–79%)1 ligoje
PNPLA2patatin like domain 2, triacylglycerol lipaseDažnai (30–79%)2 ligose
POLD1DNA polymerase delta 1, catalytic subunitDažnai (30–79%)1 ligoje
POLR3ARNA polymerase III subunit ADažnai (30–79%)2 ligose
PRF1perforin 1Dažnai (30–79%)2 ligose
RAI1retinoic acid induced 1Dažnai (30–79%)2 ligose
SCAPERS-phase cyclin A associated protein in the ERDažnai (30–79%)1 ligoje
SCLT1sodium channel and clathrin linker 1Dažnai (30–79%)1 ligoje
SDCCAG8SHH signaling and ciliogenesis regulator SDCCAG8Dažnai (30–79%)1 ligoje
SLC7A7solute carrier family 7 member 7Dažnai (30–79%)1 ligoje
STXBP2syntaxin binding protein 2Dažnai (30–79%)2 ligose
SYNE1spectrin repeat containing nuclear envelope protein 1Dažnai (30–79%)1 ligoje
SYNE2spectrin repeat containing nuclear envelope protein 2Dažnai (30–79%)1 ligoje
TBCKTBC1 domain containing kinaseDažnai (30–79%)1 ligoje
TMEM43transmembrane protein 43Dažnai (30–79%)1 ligoje
TNFRSF9TNF receptor superfamily member 9Dažnai (30–79%)1 ligoje
TRIM32tripartite motif containing 32Dažnai (30–79%)1 ligoje
TTC8tetratricopeptide repeat domain 8Dažnai (30–79%)1 ligoje
UNC13Dunc-13 homolog DDažnai (30–79%)2 ligose
WDPCPWD repeat containing planar cell polarity effectorDažnai (30–79%)1 ligoje
AEBP1AE binding protein 1Kartais (5–29%)1 ligoje
AIPAHR interacting HSP90 co-chaperoneKartais (5–29%)1 ligoje
ASLargininosuccinate lyaseKartais (5–29%)1 ligoje
DYRK1Bdual specificity tyrosine phosphorylation regulated kinase 1BKartais (5–29%)1 ligoje
GPR101G protein-coupled receptor 101Kartais (5–29%)1 ligoje
HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2Kartais (5–29%)1 ligoje
LYSTlysosomal trafficking regulatorKartais (5–29%)1 ligoje
MAGEL2MAGE family member L2Kartais (5–29%)1 ligoje
MC4Rmelanocortin 4 receptorKartais (5–29%)1 ligoje
MKRN3makorin ring finger protein 3Kartais (5–29%)1 ligoje
MTX2metaxin 2Kartais (5–29%)1 ligoje
NPAP1nuclear pore associated protein 1Kartais (5–29%)1 ligoje
PIGTphosphatidylinositol glycan anchor biosynthesis class TKartais (5–29%)1 ligoje
PSMB8proteasome 20S subunit beta 8Kartais (5–29%)1 ligoje
PWAR1Prader Willi/Angelman region RNA 1Kartais (5–29%)1 ligoje
PWRN1Prader-Willi region non-protein coding RNA 1Kartais (5–29%)1 ligoje
SLC29A3solute carrier family 29 member 3Kartais (5–29%)1 ligoje
SLC2A2solute carrier family 2 member 2Kartais (5–29%)1 ligoje
SNORD115-1small nucleolar RNA, C/D box 115-1Kartais (5–29%)1 ligoje
SNORD116-1small nucleolar RNA, C/D box 116-1Kartais (5–29%)1 ligoje
AGPAT21-acylglycerol-3-phosphate O-acyltransferase 2Neužfiksuota1 ligoje
APOA5apolipoprotein A5Neužfiksuota1 ligoje
FECHferrochelataseNeužfiksuota1 ligoje
GKglycerol kinaseNeužfiksuota1 ligoje
HAVCR2hepatitis A virus cellular receptor 2Neužfiksuota1 ligoje
JAG1jagged canonical Notch ligand 1Neužfiksuota1 ligoje
LCATlecithin-cholesterol acyltransferaseNeužfiksuota2 ligose
LRP6LDL receptor related protein 6Neužfiksuota1 ligoje
NOTCH3notch receptor 3Neužfiksuota1 ligoje
PSMB4proteasome 20S subunit beta 4Neužfiksuota1 ligoje
PYGLglycogen phosphorylase LNeužfiksuota1 ligoje
RSPO1R-spondin 1Neužfiksuota1 ligoje
SAR1Bsecretion associated Ras related GTPase 1BNeužfiksuota1 ligoje
SGPL1sphingosine-1-phosphate lyase 1Neužfiksuota1 ligoje
TTPAalpha tocopherol transfer proteinNeužfiksuota1 ligoje

Kaip dažnai šis požymis pasitaiko žmonėms, turintiems vieną iš geno sukeliamų ligų, ir kuris dažnis tarp jų didžiausias, pagal Žmogaus fenotipo ontologijos duomenis. Šiuose puslapiuose aprašomi požymiai ir juos grindžiantys tyrimai; tai nėra diagnozė, o su simptomais kreipkitės į gydytoją ar genetikos konsultantą.

Siauresni požymiai

Platesni požymiai

Elevated lipids in blood

Iš kur tai žinoma

  • Žmogaus fenotipo ontologija, 2026-09-01 leidimas: požymis, jo pavadinimai, apibrėžimas ir su juo susiję genai. Daugiau sužinokite svetainėje hpo.jax.org.
  • Duomenų leidimas 2026.10.16-c6eea6bf.

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