Trait
Increased plasma triglycerides
Clinical name: Hypertriglyceridemia
The concentration of triglyceride in the blood circulation is above the upper limit of normal.
Summary
- Also called
- Increased serum triglycerides, Increased triglycerides, Elevated triglyceride concentration, Elevated triglyceride level, Elevated triglyceride level in blood, Increased circulating Tg levels, Increased plasma Tg levels, Increased triglyceride concentration, Increased triglyceride level, Increased triglyceride level in blood
- Body system
- Laboratory abnormality
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Increased plasma triglycerides, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test131 genes linked to Increased plasma triglycerides
Changes in these genes cause rare conditions in which Increased plasma triglycerides is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ADRA2Aadrenoceptor alpha 2A | Always | In 1 condition |
| AK2adenylate kinase 2 | Always | In 1 condition |
| APOC2apolipoprotein C2 | Always | In 1 condition |
| CAV1caveolin 1 | Always | In 2 conditions |
| CIDECcell death inducing DFFA like effector c | Always | In 2 conditions |
| CREB3L3cAMP responsive element binding protein 3 like 3 | Always | In 1 condition |
| FARSAphenylalanyl-tRNA synthetase subunit alpha | Always | In 1 condition |
| GPD1glycerol-3-phosphate dehydrogenase 1 | Always | In 1 condition |
| GPIHBP1glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 | Always | In 1 condition |
| LDLRAP1low density lipoprotein receptor adaptor protein 1 | Always | In 1 condition |
| LIPClipase C, hepatic type | Always | In 2 conditions |
| LMF1lipase maturation factor 1 | Always | In 1 condition |
| MCM10minichromosome maintenance 10 replication initiation factor | Always | In 1 condition |
| NSMCE2NSE2 SUMO ligase component of SMC5/6 complex | Always | In 2 conditions |
| PCYT1Aphosphate cytidylyltransferase 1A, choline | Always | In 1 condition |
| PIK3CGphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Always | In 1 condition |
| PLIN1perilipin 1 | Always | In 2 conditions |
| PLVAPplasmalemma vesicle associated protein | Always | In 1 condition |
| PPARGperoxisome proliferator activated receptor gamma | Always | In 2 conditions |
| RBSNrabenosyn, RAB effector | Always | In 2 conditions |
| RC3H1ring finger and CCCH-type domains 1 | Always | In 1 condition |
| SLC19A1solute carrier family 19 member 1 | Always | In 1 condition |
| STX11syntaxin 11 | Always | In 2 conditions |
| SUPT7LSPT7 like, STAGA complex subunit gamma | Always | In 1 condition |
| WRNWRN RecQ like helicase | Always | In 1 condition |
| YARS1tyrosyl-tRNA synthetase 1 | Always | In 1 condition |
| ABCA1ATP binding cassette subfamily A member 1 | Very often (80–99%) | In 2 conditions |
| AGLamylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase | Very often (80–99%) | In 1 condition |
| AKT2AKT serine/threonine kinase 2 | Very often (80–99%) | In 1 condition |
| ALMS1ALMS1 centrosome and basal body associated protein | Very often (80–99%) | In 2 conditions |
| APOEapolipoprotein E | Very often (80–99%) | In 2 conditions |
| CYP7A1cytochrome P450 family 7 subfamily A member 1 | Very often (80–99%) | In 1 condition |
| LIPElipase E, hormone sensitive type | Very often (80–99%) | In 1 condition |
| LMNAlamin A/C | Very often (80–99%) | In 8 conditions |
| PHKBphosphorylase kinase regulatory subunit beta | Very often (80–99%) | In 1 condition |
| SLC25A13solute carrier family 25 member 13 | Very often (80–99%) | In 4 conditions |
| SLC37A4solute carrier family 37 member 4 | Very often (80–99%) | In 1 condition |
| SMPD1sphingomyelin phosphodiesterase 1 | Very often (80–99%) | In 3 conditions |
| XIAPX-linked inhibitor of apoptosis | Very often (80–99%) | In 1 condition |
| XRCC4X-ray repair cross complementing 4 | Very often (80–99%) | In 1 condition |
Show 91 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABHD5abhydrolase domain containing 5, lysophosphatidic acid acyltransferase | Often (30–79%) | In 1 condition |
| ADCY3adenylate cyclase 3 | Often (30–79%) | In 1 condition |
| ARL6ARF like GTPase 6 | Often (30–79%) | In 1 condition |
| BBIP1BBSome interacting protein 1 | Often (30–79%) | In 1 condition |
| BBS1Bardet-Biedl syndrome 1 | Often (30–79%) | In 1 condition |
| BBS10Bardet-Biedl syndrome 10 | Often (30–79%) | In 1 condition |
| BBS12Bardet-Biedl syndrome 12 | Often (30–79%) | In 1 condition |
| BBS2Bardet-Biedl syndrome 2 | Often (30–79%) | In 1 condition |
| BBS4Bardet-Biedl syndrome 4 | Often (30–79%) | In 1 condition |
| BBS5Bardet-Biedl syndrome 5 | Often (30–79%) | In 1 condition |
| BBS7Bardet-Biedl syndrome 7 | Often (30–79%) | In 1 condition |
| BBS9Bardet-Biedl syndrome 9 | Often (30–79%) | In 1 condition |
| BSCL2BSCL2 lipid droplet biogenesis associated, seipin | Often (30–79%) | In 3 conditions |
| CAVIN1caveolae associated protein 1 | Often (30–79%) | In 1 condition |
| CELA2Achymotrypsin like elastase 2A | Often (30–79%) | In 1 condition |
| CEP19centrosomal protein 19 | Often (30–79%) | In 2 conditions |
| CEP290centrosomal protein 290 | Often (30–79%) | In 1 condition |
| CFAP418cilia and flagella associated protein 418 | Often (30–79%) | In 1 condition |
| DEF6DEF6 guanine nucleotide exchange factor | Often (30–79%) | In 1 condition |
| EMDemerin | Often (30–79%) | In 1 condition |
| EXTL3exostosin like glycosyltransferase 3 | Often (30–79%) | In 1 condition |
| FHL1four and a half LIM domains 1 | Often (30–79%) | In 1 condition |
| GUK1guanylate kinase 1 | Often (30–79%) | In 1 condition |
| IFT172intraflagellar transport 172 | Often (30–79%) | In 1 condition |
| IFT27intraflagellar transport 27 | Often (30–79%) | In 1 condition |
| IFT74intraflagellar transport 74 | Often (30–79%) | In 1 condition |
| LEPleptin | Often (30–79%) | In 1 condition |
| LEPRleptin receptor | Often (30–79%) | In 1 condition |
| LIPAlipase A, lysosomal acid type | Often (30–79%) | In 2 conditions |
| LZTFL1leucine zipper transcription factor like 1 | Often (30–79%) | In 1 condition |
| MKKSMKKS centrosomal shuttling protein | Often (30–79%) | In 1 condition |
| MKS1MKS transition zone complex subunit 1 | Often (30–79%) | In 1 condition |
| NPHP1nephrocystin 1 | Often (30–79%) | In 1 condition |
| PHKA2phosphorylase kinase regulatory subunit alpha 2 | Often (30–79%) | In 2 conditions |
| PHKG2phosphorylase kinase catalytic subunit gamma 2 | Often (30–79%) | In 2 conditions |
| PIGHphosphatidylinositol glycan anchor biosynthesis class H | Often (30–79%) | In 1 condition |
| PLAAT3phospholipase A and acyltransferase 3 | Often (30–79%) | In 1 condition |
| PNPLA2patatin like domain 2, triacylglycerol lipase | Often (30–79%) | In 2 conditions |
| POLD1DNA polymerase delta 1, catalytic subunit | Often (30–79%) | In 1 condition |
| POLR3ARNA polymerase III subunit A | Often (30–79%) | In 2 conditions |
| PRF1perforin 1 | Often (30–79%) | In 2 conditions |
| RAI1retinoic acid induced 1 | Often (30–79%) | In 2 conditions |
| SCAPERS-phase cyclin A associated protein in the ER | Often (30–79%) | In 1 condition |
| SCLT1sodium channel and clathrin linker 1 | Often (30–79%) | In 1 condition |
| SDCCAG8SHH signaling and ciliogenesis regulator SDCCAG8 | Often (30–79%) | In 1 condition |
| SLC7A7solute carrier family 7 member 7 | Often (30–79%) | In 1 condition |
| STXBP2syntaxin binding protein 2 | Often (30–79%) | In 2 conditions |
| SYNE1spectrin repeat containing nuclear envelope protein 1 | Often (30–79%) | In 1 condition |
| SYNE2spectrin repeat containing nuclear envelope protein 2 | Often (30–79%) | In 1 condition |
| TBCKTBC1 domain containing kinase | Often (30–79%) | In 1 condition |
| TMEM43transmembrane protein 43 | Often (30–79%) | In 1 condition |
| TNFRSF9TNF receptor superfamily member 9 | Often (30–79%) | In 1 condition |
| TRIM32tripartite motif containing 32 | Often (30–79%) | In 1 condition |
| TTC8tetratricopeptide repeat domain 8 | Often (30–79%) | In 1 condition |
| UNC13Dunc-13 homolog D | Often (30–79%) | In 2 conditions |
| WDPCPWD repeat containing planar cell polarity effector | Often (30–79%) | In 1 condition |
| AEBP1AE binding protein 1 | Sometimes (5–29%) | In 1 condition |
| AIPAHR interacting HSP90 co-chaperone | Sometimes (5–29%) | In 1 condition |
| ASLargininosuccinate lyase | Sometimes (5–29%) | In 1 condition |
| DYRK1Bdual specificity tyrosine phosphorylation regulated kinase 1B | Sometimes (5–29%) | In 1 condition |
| GPR101G protein-coupled receptor 101 | Sometimes (5–29%) | In 1 condition |
| HERC2HECT and RLD domain containing E3 ubiquitin protein ligase 2 | Sometimes (5–29%) | In 1 condition |
| LYSTlysosomal trafficking regulator | Sometimes (5–29%) | In 1 condition |
| MAGEL2MAGE family member L2 | Sometimes (5–29%) | In 1 condition |
| MC4Rmelanocortin 4 receptor | Sometimes (5–29%) | In 1 condition |
| MKRN3makorin ring finger protein 3 | Sometimes (5–29%) | In 1 condition |
| MTX2metaxin 2 | Sometimes (5–29%) | In 1 condition |
| NPAP1nuclear pore associated protein 1 | Sometimes (5–29%) | In 1 condition |
| PIGTphosphatidylinositol glycan anchor biosynthesis class T | Sometimes (5–29%) | In 1 condition |
| PSMB8proteasome 20S subunit beta 8 | Sometimes (5–29%) | In 1 condition |
| PWAR1Prader Willi/Angelman region RNA 1 | Sometimes (5–29%) | In 1 condition |
| PWRN1Prader-Willi region non-protein coding RNA 1 | Sometimes (5–29%) | In 1 condition |
| SLC29A3solute carrier family 29 member 3 | Sometimes (5–29%) | In 1 condition |
| SLC2A2solute carrier family 2 member 2 | Sometimes (5–29%) | In 1 condition |
| SNORD115-1small nucleolar RNA, C/D box 115-1 | Sometimes (5–29%) | In 1 condition |
| SNORD116-1small nucleolar RNA, C/D box 116-1 | Sometimes (5–29%) | In 1 condition |
| AGPAT21-acylglycerol-3-phosphate O-acyltransferase 2 | Not recorded | In 1 condition |
| APOA5apolipoprotein A5 | Not recorded | In 1 condition |
| FECHferrochelatase | Not recorded | In 1 condition |
| GKglycerol kinase | Not recorded | In 1 condition |
| HAVCR2hepatitis A virus cellular receptor 2 | Not recorded | In 1 condition |
| JAG1jagged canonical Notch ligand 1 | Not recorded | In 1 condition |
| LCATlecithin-cholesterol acyltransferase | Not recorded | In 2 conditions |
| LRP6LDL receptor related protein 6 | Not recorded | In 1 condition |
| NOTCH3notch receptor 3 | Not recorded | In 1 condition |
| PSMB4proteasome 20S subunit beta 4 | Not recorded | In 1 condition |
| PYGLglycogen phosphorylase L | Not recorded | In 1 condition |
| RSPO1R-spondin 1 | Not recorded | In 1 condition |
| SAR1Bsecretion associated Ras related GTPase 1B | Not recorded | In 1 condition |
| SGPL1sphingosine-1-phosphate lyase 1 | Not recorded | In 1 condition |
| TTPAalpha tocopherol transfer protein | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks