Trait
Weight loss
Reduction of total body weight.
Summary
- Also called
- Loss of weight
- Body system
- Growth abnormality
Reference genomeGRCh38hg38
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Get my Genome Test353 genes linked to Weight loss
Changes in these genes cause rare conditions in which Weight loss is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ABCB7ATP binding cassette subfamily B member 7 | Always | In 1 condition |
| CTNScystinosin, lysosomal cystine transporter | Always | In 1 condition |
| FLNAfilamin A | Always | In 1 condition |
| KCNJ18potassium inwardly rectifying channel subfamily J member 18 | Always | In 2 conditions |
| KLF1KLF transcription factor 1 | Always | In 1 condition |
| POLGDNA polymerase gamma, catalytic subunit | Always | In 4 conditions |
| PTCRApre T cell antigen receptor alpha | Always | In 1 condition |
| TYMPthymidine phosphorylase | Always | In 2 conditions |
| ABCC8ATP binding cassette subfamily C member 8 | Very often (80–99%) | In 1 condition |
| ABCD3ATP binding cassette subfamily D member 3 | Very often (80–99%) | In 1 condition |
| ATMATM serine/threonine kinase | Very often (80–99%) | In 2 conditions |
| ATP7BATPase copper transporting beta | Very often (80–99%) | In 1 condition |
| BANK1B cell scaffold protein with ankyrin repeats 1 | Very often (80–99%) | In 1 condition |
| BCL10BCL10 immune signaling adaptor | Very often (80–99%) | In 1 condition |
| BCL2BCL2 apoptosis regulator | Very often (80–99%) | In 1 condition |
| BCL6BCL6 transcription repressor | Very often (80–99%) | In 1 condition |
| BIRC3baculoviral IAP repeat containing 3 | Very often (80–99%) | In 1 condition |
| BLKBLK proto-oncogene, Src family tyrosine kinase | Very often (80–99%) | In 1 condition |
| BMPR1Abone morphogenetic protein receptor type 1A | Very often (80–99%) | In 1 condition |
| BRCA1BRCA1 DNA repair associated | Very often (80–99%) | In 2 conditions |
| BRCA2BRCA2 DNA repair associated | Very often (80–99%) | In 4 conditions |
| C4Acomplement C4A (Chido/Rodgers blood group) | Very often (80–99%) | In 2 conditions |
| C4Bcomplement C4B (Chido/Rodgers blood group) | Very often (80–99%) | In 1 condition |
| CDKN2Acyclin dependent kinase inhibitor 2A | Very often (80–99%) | In 2 conditions |
| CHEK2checkpoint kinase 2 | Very often (80–99%) | In 2 conditions |
| CR2complement C3d receptor 2 | Very often (80–99%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Very often (80–99%) | In 3 conditions |
| DCTN1dynactin subunit 1 | Very often (80–99%) | In 3 conditions |
| DNASE1deoxyribonuclease 1 | Very often (80–99%) | In 1 condition |
| EPCAMepithelial cell adhesion molecule | Very often (80–99%) | In 2 conditions |
| ETS1ETS proto-oncogene 1, transcription factor | Very often (80–99%) | In 1 condition |
| FCGR2BFc gamma receptor IIb | Very often (80–99%) | In 1 condition |
| FCGR3BFc gamma receptor IIIb | Very often (80–99%) | In 1 condition |
| FOXP1forkhead box P1 | Very often (80–99%) | In 1 condition |
| GCKglucokinase | Very often (80–99%) | In 1 condition |
| GIPC1GIPC PDZ domain containing family member 1 | Very often (80–99%) | In 1 condition |
| GJA1gap junction protein alpha 1 | Very often (80–99%) | In 1 condition |
| GJB3gap junction protein beta 3 | Very often (80–99%) | In 1 condition |
| GJB4gap junction protein beta 4 | Very often (80–99%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Very often (80–99%) | In 5 conditions |
Show 313 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| HLA-DPA1major histocompatibility complex, class II, DP alpha 1 | Very often (80–99%) | In 1 condition |
| HLA-DPB1major histocompatibility complex, class II, DP beta 1 | Very often (80–99%) | In 2 conditions |
| HLA-DQB1major histocompatibility complex, class II, DQ beta 1 | Very often (80–99%) | In 3 conditions |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Very often (80–99%) | In 7 conditions |
| HLCSholocarboxylase synthetase | Very often (80–99%) | In 1 condition |
| IGHimmunoglobulin heavy locus | Very often (80–99%) | In 3 conditions |
| IGHG1immunoglobulin heavy constant gamma 1 (G1m marker) | Very often (80–99%) | In 1 condition |
| IKZF1IKAROS family zinc finger 1 | Very often (80–99%) | In 1 condition |
| IL10interleukin 10 | Very often (80–99%) | In 3 conditions |
| IL12Binterleukin 12B | Very often (80–99%) | In 1 condition |
| INSinsulin | Very often (80–99%) | In 1 condition |
| IRAK1interleukin 1 receptor associated kinase 1 | Very often (80–99%) | In 1 condition |
| IRF5interferon regulatory factor 5 | Very often (80–99%) | In 1 condition |
| ITGAMintegrin subunit alpha M | Very often (80–99%) | In 1 condition |
| JAK2Janus kinase 2 | Very often (80–99%) | In 3 conditions |
| JAZF1JAZF zinc finger 1 | Very often (80–99%) | In 1 condition |
| KCNJ11potassium inwardly rectifying channel subfamily J member 11 | Very often (80–99%) | In 1 condition |
| KDSR3-ketodihydrosphingosine reductase | Very often (80–99%) | In 1 condition |
| KIAA0319LKIAA0319 like | Very often (80–99%) | In 1 condition |
| KRASKRas proto-oncogene, GTPase | Very often (80–99%) | In 2 conditions |
| KRT1keratin 1 | Very often (80–99%) | In 1 condition |
| KRT10keratin 10 | Very often (80–99%) | In 1 condition |
| LMNAlamin A/C | Very often (80–99%) | In 1 condition |
| LPIN2lipin 2 | Very often (80–99%) | In 1 condition |
| LRP12LDL receptor related protein 12 | Very often (80–99%) | In 3 conditions |
| MALT1MALT1 paracaspase | Very often (80–99%) | In 1 condition |
| MECP2methyl-CpG binding protein 2 | Very often (80–99%) | In 1 condition |
| MLH1mutL homolog 1 | Very often (80–99%) | In 1 condition |
| MLXMAX dimerization protein MLX | Very often (80–99%) | In 1 condition |
| MSH2mutS homolog 2 | Very often (80–99%) | In 1 condition |
| MSH6mutS homolog 6 | Very often (80–99%) | In 1 condition |
| MUTYHmutY DNA glycosylase | Very often (80–99%) | In 1 condition |
| NOTCH2NLCnotch 2 N-terminal like C | Very often (80–99%) | In 1 condition |
| NPATnuclear protein, coactivator of histone transcription | Very often (80–99%) | In 1 condition |
| NUTM2B-AS1NUTM2B antisense RNA 1 | Very often (80–99%) | In 1 condition |
| P4HA2prolyl 4-hydroxylase subunit alpha 2 | Very often (80–99%) | In 1 condition |
| PALB2partner and localizer of BRCA2 | Very often (80–99%) | In 2 conditions |
| PALLDpalladin, cytoskeletal associated protein | Very often (80–99%) | In 1 condition |
| PDCD1programmed cell death 1 | Very often (80–99%) | In 1 condition |
| PDX1pancreatic and duodenal homeobox 1 | Very often (80–99%) | In 1 condition |
| PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Very often (80–99%) | In 1 condition |
| PMS1PMS1 homolog 1, mismatch repair system component | Very often (80–99%) | In 1 condition |
| PMS2PMS1 homolog 2, mismatch repair system component | Very often (80–99%) | In 1 condition |
| POLD1DNA polymerase delta 1, catalytic subunit | Very often (80–99%) | In 1 condition |
| POLEDNA polymerase epsilon, catalytic subunit | Very often (80–99%) | In 1 condition |
| PRTN3proteinase 3 | Very often (80–99%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Very often (80–99%) | In 4 conditions |
| PXKPX domain containing serine/threonine kinase like | Very often (80–99%) | In 1 condition |
| RABL3RAB, member of RAS oncogene family like 3 | Very often (80–99%) | In 1 condition |
| RILPL1Rab interacting lysosomal protein like 1 | Very often (80–99%) | In 1 condition |
| RPS20ribosomal protein S20 | Very often (80–99%) | In 1 condition |
| SEMA4Asemaphorin 4A | Very often (80–99%) | In 1 condition |
| SLC5A1solute carrier family 5 member 1 | Very often (80–99%) | In 1 condition |
| SMAD4SMAD family member 4 | Very often (80–99%) | In 1 condition |
| SPP1secreted phosphoprotein 1 | Very often (80–99%) | In 1 condition |
| STAT3signal transducer and activator of transcription 3 | Very often (80–99%) | In 2 conditions |
| STAT4signal transducer and activator of transcription 4 | Very often (80–99%) | In 3 conditions |
| TGFBR2transforming growth factor beta receptor 2 | Very often (80–99%) | In 1 condition |
| TLR7toll like receptor 7 | Very often (80–99%) | In 1 condition |
| TNFAIP3TNF alpha induced protein 3 | Very often (80–99%) | In 1 condition |
| TNFSF4TNF superfamily member 4 | Very often (80–99%) | In 1 condition |
| TNIP1TNFAIP3 interacting protein 1 | Very often (80–99%) | In 1 condition |
| TP53tumor protein p53 | Very often (80–99%) | In 3 conditions |
| TREX1three prime repair exonuclease 1 | Very often (80–99%) | In 1 condition |
| TSHRthyroid stimulating hormone receptor | Very often (80–99%) | In 2 conditions |
| UBE2L3ubiquitin conjugating enzyme E2 L3 | Very often (80–99%) | In 1 condition |
| ZMPSTE24zinc metallopeptidase STE24 | Very often (80–99%) | In 1 condition |
| AAASaladin WD repeat nucleoporin | Often (30–79%) | In 1 condition |
| ABCD1ATP binding cassette subfamily D member 1 | Often (30–79%) | In 1 condition |
| ACTA1actin alpha 1, skeletal muscle | Often (30–79%) | In 1 condition |
| AK2adenylate kinase 2 | Often (30–79%) | In 1 condition |
| ALKALK receptor tyrosine kinase | Often (30–79%) | In 1 condition |
| ANGangiogenin | Often (30–79%) | In 1 condition |
| ANO1anoctamin 1 | Often (30–79%) | In 1 condition |
| ANXA11annexin A11 | Often (30–79%) | In 1 condition |
| ASXL1ASXL transcriptional regulator 1 | Often (30–79%) | In 2 conditions |
| ATP7AATPase copper transporting alpha | Often (30–79%) | In 1 condition |
| ATRXATRX chromatin remodeler | Often (30–79%) | In 1 condition |
| ATXN2ataxin 2 | Often (30–79%) | In 1 condition |
| AVParginine vasopressin | Often (30–79%) | In 1 condition |
| B2Mbeta-2-microglobulin | Often (30–79%) | In 1 condition |
| BAP1BRCA1 associated deubiquitinase 1 | Often (30–79%) | In 1 condition |
| BCORBCL6 corepressor | Often (30–79%) | In 1 condition |
| BTNL2butyrophilin like 2 | Often (30–79%) | In 1 condition |
| CACNA1Scalcium voltage-gated channel subunit alpha1 S | Often (30–79%) | In 2 conditions |
| CBLCbl proto-oncogene | Often (30–79%) | In 1 condition |
| CCND1cyclin D1 | Often (30–79%) | In 2 conditions |
| CCNFcyclin F | Often (30–79%) | In 1 condition |
| CDC73cell division cycle 73 | Often (30–79%) | In 1 condition |
| CDH23cadherin related 23 | Often (30–79%) | In 1 condition |
| CDKN1Bcyclin dependent kinase inhibitor 1B | Often (30–79%) | In 1 condition |
| CDKN2Bcyclin dependent kinase inhibitor 2B | Often (30–79%) | In 1 condition |
| CFAP410cilia and flagella associated protein 410 | Often (30–79%) | In 1 condition |
| CHCHD10coiled-coil-helix-coiled-coil-helix domain containing 10 | Often (30–79%) | In 1 condition |
| CHMP2Bcharged multivesicular body protein 2B | Often (30–79%) | In 1 condition |
| CRLF1cytokine receptor like factor 1 | Often (30–79%) | In 1 condition |
| CTNNB1catenin beta 1 | Often (30–79%) | In 1 condition |
| DAOD-amino acid oxidase | Often (30–79%) | In 1 condition |
| DLSTdihydrolipoamide S-succinyltransferase | Often (30–79%) | In 1 condition |
| DNMT3ADNA methyltransferase 3 alpha | Often (30–79%) | In 1 condition |
| ECE1endothelin converting enzyme 1 | Often (30–79%) | In 1 condition |
| EDN3endothelin 3 | Often (30–79%) | In 1 condition |
| EDNRBendothelin receptor type B | Often (30–79%) | In 1 condition |
| EHHADHenoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase | Often (30–79%) | In 1 condition |
| ELF4E74 like ETS transcription factor 4 | Often (30–79%) | In 1 condition |
| EPAS1endothelial PAS domain protein 1 | Often (30–79%) | In 1 condition |
| ERBB2erb-b2 receptor tyrosine kinase 2 | Often (30–79%) | In 1 condition |
| ERBB3erb-b2 receptor tyrosine kinase 3 | Often (30–79%) | In 1 condition |
| ERBB4erb-b2 receptor tyrosine kinase 4 | Often (30–79%) | In 1 condition |
| EWSR1EWS RNA binding protein 1 | Often (30–79%) | In 1 condition |
| FHfumarate hydratase | Often (30–79%) | In 1 condition |
| FIG4FIG4 phosphoinositide 5-phosphatase | Often (30–79%) | In 1 condition |
| FIP1L1factor interacting with PAPOLA and CPSF1 | Often (30–79%) | In 1 condition |
| FUSFUS RNA binding protein | Often (30–79%) | In 1 condition |
| GABRA3gamma-aminobutyric acid type A receptor subunit alpha3 | Often (30–79%) | In 1 condition |
| GATA2GATA binding protein 2 | Often (30–79%) | In 1 condition |
| GATA4GATA binding protein 4 | Often (30–79%) | In 1 condition |
| GATMglycine amidinotransferase | Often (30–79%) | In 1 condition |
| GDNFglial cell derived neurotrophic factor | Often (30–79%) | In 1 condition |
| GLE1GLE1 RNA export mediator | Often (30–79%) | In 1 condition |
| GLT8D1glycosyltransferase 8 domain containing 1 | Often (30–79%) | In 1 condition |
| GMPPAGDP-mannose pyrophosphorylase A | Often (30–79%) | In 1 condition |
| GPR35G protein-coupled receptor 35 | Often (30–79%) | In 1 condition |
| HACD13-hydroxyacyl-CoA dehydratase 1 | Often (30–79%) | In 1 condition |
| HACE1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 | Often (30–79%) | In 1 condition |
| HAVCR2hepatitis A virus cellular receptor 2 | Often (30–79%) | In 1 condition |
| HLA-DQA1major histocompatibility complex, class II, DQ alpha 1 | Often (30–79%) | In 2 conditions |
| HNRNPA1heterogeneous nuclear ribonucleoprotein A1 | Often (30–79%) | In 1 condition |
| HTThuntingtin | Often (30–79%) | In 2 conditions |
| IRF2BP2interferon regulatory factor 2 binding protein 2 | Often (30–79%) | In 1 condition |
| ITGA7integrin subunit alpha 7 | Often (30–79%) | In 1 condition |
| KIF1Bkinesin family member 1B | Often (30–79%) | In 2 conditions |
| KITKIT proto-oncogene, receptor tyrosine kinase | Often (30–79%) | In 1 condition |
| LIG3DNA ligase 3 | Often (30–79%) | In 1 condition |
| LIN28Blin-28 RNA binding posttranscriptional regulator B | Often (30–79%) | In 1 condition |
| LMO1LIM domain only 1 | Often (30–79%) | In 1 condition |
| MAP3K20mitogen-activated protein kinase kinase kinase 20 | Often (30–79%) | In 1 condition |
| MATR3matrin 3 | Often (30–79%) | In 1 condition |
| MAXMYC associated transcriptional regulator X | Often (30–79%) | In 1 condition |
| MC2Rmelanocortin 2 receptor | Often (30–79%) | In 1 condition |
| MDH2malate dehydrogenase 2 | Often (30–79%) | In 1 condition |
| MEN1menin 1 | Often (30–79%) | In 1 condition |
| MRAPmelanocortin 2 receptor accessory protein | Often (30–79%) | In 1 condition |
| MST1macrophage stimulating 1 | Often (30–79%) | In 1 condition |
| MYCNMYCN proto-oncogene, bHLH transcription factor | Often (30–79%) | In 1 condition |
| MYL2myosin light chain 2 | Often (30–79%) | In 1 condition |
| NABP1nucleic acid binding protein 1 | Often (30–79%) | In 1 condition |
| NDUFAF6NADH:ubiquinone oxidoreductase complex assembly factor 6 | Often (30–79%) | In 1 condition |
| NEFHneurofilament heavy chain | Often (30–79%) | In 1 condition |
| NEK1NIMA related kinase 1 | Often (30–79%) | In 1 condition |
| NF1neurofibromin 1 | Often (30–79%) | In 1 condition |
| NNTnicotinamide nucleotide transhydrogenase | Often (30–79%) | In 1 condition |
| NOD2nucleotide binding oligomerization domain containing 2 | Often (30–79%) | In 2 conditions |
| NOS1nitric oxide synthase 1 | Often (30–79%) | In 1 condition |
| NPM1nucleophosmin 1 | Often (30–79%) | In 1 condition |
| NRTNneurturin | Often (30–79%) | In 1 condition |
| NUMA1nuclear mitotic apparatus protein 1 | Often (30–79%) | In 1 condition |
| OPTNoptineurin | Often (30–79%) | In 1 condition |
| PFN1profilin 1 | Often (30–79%) | In 1 condition |
| PHOX2Bpaired like homeobox 2B | Often (30–79%) | In 1 condition |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Often (30–79%) | In 1 condition |
| PMLPML nuclear body scaffold | Often (30–79%) | In 1 condition |
| PRKAR1Aprotein kinase cAMP-dependent type I regulatory subunit alpha | Often (30–79%) | In 2 conditions |
| PRPHperipherin | Often (30–79%) | In 1 condition |
| RARAretinoic acid receptor alpha | Often (30–79%) | In 1 condition |
| RETret proto-oncogene | Often (30–79%) | In 3 conditions |
| RHBDF2rhomboid 5 homolog 2 | Often (30–79%) | In 1 condition |
| RRM2Bribonucleotide reductase regulatory TP53 inducible subunit M2B | Often (30–79%) | In 2 conditions |
| RUNX1RUNX family transcription factor 1 | Often (30–79%) | In 1 condition |
| SDHAsuccinate dehydrogenase complex flavoprotein subunit A | Often (30–79%) | In 3 conditions |
| SDHAF1succinate dehydrogenase complex assembly factor 1 | Often (30–79%) | In 1 condition |
| SDHAF2succinate dehydrogenase complex assembly factor 2 | Often (30–79%) | In 1 condition |
| SDHBsuccinate dehydrogenase complex iron sulfur subunit B | Often (30–79%) | In 4 conditions |
| SDHCsuccinate dehydrogenase complex subunit C | Often (30–79%) | In 2 conditions |
| SDHDsuccinate dehydrogenase complex subunit D | Often (30–79%) | In 4 conditions |
| SELENONselenoprotein N | Often (30–79%) | In 1 condition |
| SEMA3Csemaphorin 3C | Often (30–79%) | In 1 condition |
| SEMA3Dsemaphorin 3D | Often (30–79%) | In 1 condition |
| SEMA4Dsemaphorin 4D | Often (30–79%) | In 1 condition |
| SLC25A11solute carrier family 25 member 11 | Often (30–79%) | In 1 condition |
| SLC2A3solute carrier family 2 member 3 | Often (30–79%) | In 1 condition |
| SLC34A1solute carrier family 34 member 1 | Often (30–79%) | In 1 condition |
| SMOsmoothened, frizzled class receptor | Often (30–79%) | In 1 condition |
| SOD1superoxide dismutase 1 | Often (30–79%) | In 1 condition |
| SQSTM1sequestosome 1 | Often (30–79%) | In 1 condition |
| SREBF1sterol regulatory element binding transcription factor 1 | Often (30–79%) | In 1 condition |
| SRSF2serine and arginine rich splicing factor 2 | Often (30–79%) | In 2 conditions |
| STARsteroidogenic acute regulatory protein | Often (30–79%) | In 1 condition |
| STAT1signal transducer and activator of transcription 1 | Often (30–79%) | In 1 condition |
| STAT5Bsignal transducer and activator of transcription 5B | Often (30–79%) | In 1 condition |
| SYKspleen associated tyrosine kinase | Often (30–79%) | In 1 condition |
| TAF15TATA-box binding protein associated factor 15 | Often (30–79%) | In 1 condition |
| TARDBPTAR DNA binding protein | Often (30–79%) | In 1 condition |
| TBK1TANK binding kinase 1 | Often (30–79%) | In 1 condition |
| TBL1XR1TBL1X/Y related 1 | Often (30–79%) | In 1 condition |
| TCF4transcription factor 4 | Often (30–79%) | In 1 condition |
| TERTtelomerase reverse transcriptase | Often (30–79%) | In 1 condition |
| TET2tet methylcytosine dioxygenase 2 | Often (30–79%) | In 2 conditions |
| TMEM127transmembrane protein 127 | Often (30–79%) | In 1 condition |
| TPM2tropomyosin 2 | Often (30–79%) | In 1 condition |
| TPM3tropomyosin 3 | Often (30–79%) | In 1 condition |
| TRAPPC11trafficking protein particle complex subunit 11 | Often (30–79%) | In 1 condition |
| TREM2triggering receptor expressed on myeloid cells 2 | Often (30–79%) | In 1 condition |
| TTRtransthyretin | Often (30–79%) | In 1 condition |
| TXNRD2thioredoxin reductase 2 | Often (30–79%) | In 1 condition |
| UBQLN2ubiquilin 2 | Often (30–79%) | In 1 condition |
| UNC13Aunc-13 homolog A | Often (30–79%) | In 1 condition |
| VAPBVAMP associated protein B and C | Often (30–79%) | In 1 condition |
| VCPvalosin containing protein | Often (30–79%) | In 1 condition |
| VHLvon Hippel-Lindau tumor suppressor | Often (30–79%) | In 2 conditions |
| WT1WT1 transcription factor | Often (30–79%) | In 2 conditions |
| ZBTB16zinc finger and BTB domain containing 16 | Often (30–79%) | In 1 condition |
| ZNRF3zinc and ring finger 3 | Often (30–79%) | In 1 condition |
| ACAT1acetyl-CoA acetyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| AMNamnion associated transmembrane protein | Sometimes (5–29%) | In 1 condition |
| ANKRD55ankyrin repeat domain 55 | Sometimes (5–29%) | In 1 condition |
| BMP6bone morphogenetic protein 6 | Sometimes (5–29%) | In 1 condition |
| BRIP1BRCA1 interacting DNA helicase 1 | Sometimes (5–29%) | In 1 condition |
| BTKBruton tyrosine kinase | Sometimes (5–29%) | In 1 condition |
| CALRcalreticulin | Sometimes (5–29%) | In 1 condition |
| CCR1C-C motif chemokine receptor 1 | Sometimes (5–29%) | In 1 condition |
| CD247CD247 molecule | Sometimes (5–29%) | In 1 condition |
| COL4A5collagen type IV alpha 5 chain | Sometimes (5–29%) | In 1 condition |
| COL4A6collagen type IV alpha 6 chain | Sometimes (5–29%) | In 1 condition |
| CTR9CTR9 component of Paf1/RNA polymerase II complex | Sometimes (5–29%) | In 1 condition |
| CTRCchymotrypsin C | Sometimes (5–29%) | In 1 condition |
| CUBNcubilin | Sometimes (5–29%) | In 1 condition |
| DIS3L2DIS3 like 3'-5' exoribonuclease 2 | Sometimes (5–29%) | In 1 condition |
| DNAJC13DnaJ heat shock protein family (Hsp40) member C13 | Sometimes (5–29%) | In 1 condition |
| EIF4G1eukaryotic translation initiation factor 4 gamma 1 | Sometimes (5–29%) | In 1 condition |
| ERAP1endoplasmic reticulum aminopeptidase 1 | Sometimes (5–29%) | In 1 condition |
| ERCC4ERCC excision repair 4, endonuclease catalytic subunit | Sometimes (5–29%) | In 1 condition |
| F5coagulation factor V | Sometimes (5–29%) | In 1 condition |
| FAAP100FA core complex associated protein 100 | Sometimes (5–29%) | In 1 condition |
| FANCAFA complementation group A | Sometimes (5–29%) | In 1 condition |
| FANCBFA complementation group B | Sometimes (5–29%) | In 1 condition |
| FANCCFA complementation group C | Sometimes (5–29%) | In 1 condition |
| FANCD2FA complementation group D2 | Sometimes (5–29%) | In 1 condition |
| FANCEFA complementation group E | Sometimes (5–29%) | In 1 condition |
| FANCFFA complementation group F | Sometimes (5–29%) | In 1 condition |
| FANCGFA complementation group G | Sometimes (5–29%) | In 1 condition |
| FANCIFA complementation group I | Sometimes (5–29%) | In 1 condition |
| FANCLFA complementation group L | Sometimes (5–29%) | In 1 condition |
| FANCMFA complementation group M | Sometimes (5–29%) | In 1 condition |
| FASFas cell surface death receptor | Sometimes (5–29%) | In 1 condition |
| FLI1Fli-1 proto-oncogene, ETS transcription factor | Sometimes (5–29%) | In 1 condition |
| GALCgalactosylceramidase | Sometimes (5–29%) | In 1 condition |
| GBA1glucosylceramidase beta 1 | Sometimes (5–29%) | In 1 condition |
| GIGYF2GRB10 interacting GYF protein 2 | Sometimes (5–29%) | In 1 condition |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Sometimes (5–29%) | In 1 condition |
| GPC3glypican 3 | Sometimes (5–29%) | In 1 condition |
| H19H19 imprinted maternally expressed transcript | Sometimes (5–29%) | In 1 condition |
| HFEhomeostatic iron regulator | Sometimes (5–29%) | In 1 condition |
| HMGCL3-hydroxy-3-methylglutaryl-CoA lyase | Sometimes (5–29%) | In 1 condition |
| IFIH1interferon induced with helicase C domain 1 | Sometimes (5–29%) | In 1 condition |
| IFNGR1interferon gamma receptor 1 | Sometimes (5–29%) | In 2 conditions |
| IL12Ainterleukin 12A | Sometimes (5–29%) | In 1 condition |
| IL12A-AS1IL12A antisense RNA 1 | Sometimes (5–29%) | In 1 condition |
| IL23Rinterleukin 23 receptor | Sometimes (5–29%) | In 1 condition |
| IL2RAinterleukin 2 receptor subunit alpha | Sometimes (5–29%) | In 1 condition |
| IL2RBinterleukin 2 receptor subunit beta | Sometimes (5–29%) | In 1 condition |
| IVDisovaleryl-CoA dehydrogenase | Sometimes (5–29%) | In 1 condition |
| JPH3junctophilin 3 | Sometimes (5–29%) | In 2 conditions |
| KLRC4killer cell lectin like receptor C4 | Sometimes (5–29%) | In 1 condition |
| LRRK2leucine rich repeat kinase 2 | Sometimes (5–29%) | In 1 condition |
| MAD2L2mitotic arrest deficient 2 like 2 | Sometimes (5–29%) | In 1 condition |
| MAP2K1mitogen-activated protein kinase kinase 1 | Sometimes (5–29%) | In 1 condition |
| MEFVMEFV innate immunity regulator, pyrin | Sometimes (5–29%) | In 1 condition |
| MPLMPL proto-oncogene, thrombopoietin receptor | Sometimes (5–29%) | In 1 condition |
| NAB2NGFI-A binding protein 2 | Sometimes (5–29%) | In 1 condition |
| NR0B1nuclear receptor subfamily 0 group B member 1 | Sometimes (5–29%) | In 1 condition |
| NRASNRAS proto-oncogene, GTPase | Sometimes (5–29%) | In 1 condition |
| PANK2pantothenate kinase 2 | Sometimes (5–29%) | In 1 condition |
| PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin | Sometimes (5–29%) | In 1 condition |
| POU6F2POU class 6 homeobox 2 | Sometimes (5–29%) | In 1 condition |
| PRNPprion protein (Kanno blood group) | Sometimes (5–29%) | In 4 conditions |
| PSAPprosaposin | Sometimes (5–29%) | In 1 condition |
| PTPN2protein tyrosine phosphatase non-receptor type 2 | Sometimes (5–29%) | In 1 condition |
| RAD51RAD51 recombinase | Sometimes (5–29%) | In 1 condition |
| RAD51CRAD51 paralog C | Sometimes (5–29%) | In 1 condition |
| RESTRE1 silencing transcription factor | Sometimes (5–29%) | In 1 condition |
| RFWD3ring finger and WD repeat domain 3 | Sometimes (5–29%) | In 1 condition |
| RNF168ring finger protein 168 | Sometimes (5–29%) | In 1 condition |
| RNU7-1RNA, U7 small nuclear 1 | Sometimes (5–29%) | In 1 condition |
| SCNN1Asodium channel epithelial 1 subunit alpha | Sometimes (5–29%) | In 1 condition |
| SCNN1Bsodium channel epithelial 1 subunit beta | Sometimes (5–29%) | In 1 condition |
| SCNN1Gsodium channel epithelial 1 subunit gamma | Sometimes (5–29%) | In 1 condition |
| SLC34A2solute carrier family 34 member 2 | Sometimes (5–29%) | In 1 condition |
| SLC39A4solute carrier family 39 member 4 | Sometimes (5–29%) | In 1 condition |
| SLX4SLX4 structure-specific endonuclease subunit | Sometimes (5–29%) | In 1 condition |
| SNCAsynuclein alpha | Sometimes (5–29%) | In 2 conditions |
| SPINK1serine peptidase inhibitor Kazal type 1 | Sometimes (5–29%) | In 1 condition |
| STAT6signal transducer and activator of transcription 6 | Sometimes (5–29%) | In 1 condition |
| THPOthrombopoietin | Sometimes (5–29%) | In 1 condition |
| TLR4toll like receptor 4 | Sometimes (5–29%) | In 1 condition |
| TRIM28tripartite motif containing 28 | Sometimes (5–29%) | In 1 condition |
| TRIP13thyroid hormone receptor interactor 13 | Sometimes (5–29%) | In 1 condition |
| TWNKtwinkle mtDNA helicase | Sometimes (5–29%) | In 1 condition |
| UBAC2UBA domain containing 2 | Sometimes (5–29%) | In 1 condition |
| UBE2Tubiquitin conjugating enzyme E2 T | Sometimes (5–29%) | In 1 condition |
| UNC45Aunc-45 myosin chaperone A | Sometimes (5–29%) | In 1 condition |
| VPS13Avacuolar protein sorting 13 homolog A | Sometimes (5–29%) | In 1 condition |
| VPS35VPS35 retromer complex component | Sometimes (5–29%) | In 1 condition |
| XRCC2X-ray repair cross complementing 2 | Sometimes (5–29%) | In 1 condition |
| CD28CD28 molecule | Rarely (1–4%) | In 1 condition |
| RB1RB transcriptional corepressor 1 | Rarely (1–4%) | In 1 condition |
| TNFRSF1BTNF receptor superfamily member 1B | Rarely (1–4%) | In 1 condition |
| CD244CD244 molecule | Not recorded | In 1 condition |
| CIITAclass II major histocompatibility complex transactivator | Not recorded | In 1 condition |
| CYP24A1cytochrome P450 family 24 subfamily A member 1 | Not recorded | In 1 condition |
| IL6interleukin 6 | Not recorded | In 1 condition |
| NFKBIL1NFKB inhibitor like 1 | Not recorded | In 1 condition |
| SLC22A4solute carrier family 22 member 4 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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