Gene
CFAP410
cilia and flagella associated protein 410
- HGNC 1260(opens in a new tab)
- Ensembl gene ENSG00000160226(opens in a new tab)
- NCBI Gene 755(opens in a new tab)
Summary
- Cytogenetic location
- 21q22.3
- Coordinates
- Chromosome 21: 44,328,944–44,339,390 (GRCh38)
- Exons
- 7 exons across 10.4 kb
- Protein
- 256 amino acids
- Also known as
- YF5, A2, LRRC76
- Previous symbols
- C21orf2
- MANE Select transcript
- ENST00000339818.9NM_004928.3
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome TestCurated reports relevant to this gene
No Genome Test report reads CFAP410 yet. The test sequences your whole genome, so your data includes it all the same.
How CFAP410 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.2 kb of the gene's 10.4 kb; 771 of those bases code for the protein.
How a genome test reads CFAP410
21
positions in CFAP410 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 10.4 kb of CFAP410, introns included, not only the 2.2 kb of exons.
Traits linked to CFAP410
The Human Phenotype Ontology lists these as features of the rare conditions CFAP410 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the eye
- Breakdown of light-sensitive cells in back of eye
- Difficulties with night vision
- Optic atrophy
- Posterior staphyloma
- Retinal pigment epithelial mottling
- Abnormal retinal pigmentation
- Cone/cone-rod dystrophy
- Extreme sensitivity of the eyes to light
Show 16 more traits
- Rod-cone dystrophy
- Abnormal color vision
- Abnormal full-field electroretinogram
- Blind spot located at fixation point
- Color blindness
- Decreased clarity of vision
- Optic disc pallor
- Posterior subcapsular cataract
- Progressive loss of vision
- Retinal atrophy
- Spicular pigmentation of the retina
- Involuntary, rapid, rhythmic eye movements
- Metamorphopsia
- Visual impairment
- Retina degeneration
- Yellowish cloudy center of lens
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). CFAP410 gene: cilia and flagella associated protein 410. Retrieved 17 October 2026, from https://dantelabs.com/genes/cfap410
Dante Labs. CFAP410 gene: cilia and flagella associated protein 410 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/cfap410
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