Gene
FCGR3B
Fc gamma receptor IIIb
- HGNC 3620↗(opens in a new tab)
- Ensembl gene ENSG00000162747↗(opens in a new tab)
- NCBI Gene 2215↗(opens in a new tab)
Summary
- Cytogenetic location
- 1q23.3
- Coordinates
- Chromosome 1: 161,623,196–161,631,176 (GRCh38)
- Exons
- 5 exons across 8 kb
- Protein
- 233 amino acids
- Also known as
- HNA-1, CD16, CD16b, FcgammaRIIIb, FcRIIIb
- Previous symbols
- FCGR3, FCG3
- MANE Select transcript
- ENST00000650385.1NM_001244753.2
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How FCGR3B is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.1 kb of the gene's 8 kb; 702 of those bases code for the protein.
Traits linked to FCGR3B
The Human Phenotype Ontology lists these as features of the rare conditions FCGR3B can cause. Each trait's page lists the other genes linked to it.
Abnormality of the immune system
- Antineutrophil antibody positivity
- Antinuclear antibody positivity
- Anti-complement component C1q antibody positivity
- Anti-ribosome Po antibody positivity
- Anti-titin antibody positivity
- Decreased circulating complement C3 concentration
- Decreased circulating complement C4 concentration
- Malar rash
Show 13 more traits
- Pneumonia
- Severe infection
- Anti-dsDNA antibody positivity
- Anti-La/SS-B antibody positivity
- Anti-nucleoporin 62 antibody positivity
- Anti-phosphatidic acid antibody positivity
- Anti-Ro52/TRIM21 antibody positivity
- Anti-Sm antibody positivity
- Anti-U1 ribonucleoprotein antibody positivity
- Discoid lupus rash
- Infection in blood stream
- Meningitis
- Serositis
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). FCGR3B gene: Fc gamma receptor IIIb. Retrieved 16 October 2026, from https://dantelabs.com/genes/fcgr3b
Dante Labs. FCGR3B gene: Fc gamma receptor IIIb [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/fcgr3b
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