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Gene

MYCN

MYCN proto-oncogene, bHLH transcription factor

Summary

Cytogenetic location
2p24.3
Coordinates
Chromosome 2: 15,940,550–15,947,004 (GRCh38)
Exons
3 exons across 6.5 kb
Protein
464 amino acids
Also known as
bHLHe37, N-myc, MYCNOT
Previous symbols
NMYC
MANE Select transcript
ENST00000281043.4NM_005378.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MYCN yet. The test sequences your whole genome, so your data includes it all the same.

How MYCN is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 2, with a bracket where MYCN sits. MYCN and 2 genes near it on chromosome 2, from 15,443,777 to 16,443,776.Chromosome 22p24.3p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.315.6 Mb15.8 Mb16 Mb16.2 Mb16.4 MbNBAS: 15,166,913–15,561,340, reverse strandNBASDDX1: 15,591,178–15,634,346, forward strandDDX1MYCN: 15,940,550–15,947,004, forward strandMYCNDiagram of MYCN: 3 exons on the forward strand of chromosome 2Exon 2: 17 known disease-causing sitesExon 3: 15 known disease-causing sitesExon 1: 15,940,550–15,940,743, 194 basesExon 2: 15,941,948–15,942,854, 907 basesExon 3: 15,945,493–15,947,004, 1,512 bases1235′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.6 kb of the gene's 6.5 kb; 1,395 of those bases code for the protein.

How a genome test reads MYCN

32

positions in MYCN where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 6.5 kb of MYCN, introns included, not only the 2.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). MYCN gene: MYCN proto-oncogene, bHLH transcription factor. Retrieved 17 October 2026, from https://dantelabs.com/genes/mycn

Vancouver

Dante Labs. MYCN gene: MYCN proto-oncogene, bHLH transcription factor [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mycn

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