Gene
FCGR2B
Fc gamma receptor IIb
- HGNC 3618↗(opens in a new tab)
- Ensembl gene ENSG00000072694↗(opens in a new tab)
- NCBI Gene 2213↗(opens in a new tab)
Summary
- Cytogenetic location
- 1q23.3
- Coordinates
- Chromosome 1: 161,663,143–161,678,654 (GRCh38)
- Exons
- 8 exons across 15.5 kb
- Protein
- 310 amino acids
- Also known as
- CD32, CD32B, FcgammaRIIb, FcGRIIB
- Previous symbols
- FCG2, FCGR2
- MANE Select transcript
- ENST00000358671.10NM_001394477.1
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How FCGR2B is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.1 kb of the gene's 15.5 kb; 933 of those bases code for the protein.
Traits linked to FCGR2B
The Human Phenotype Ontology lists these as features of the rare conditions FCGR2B can cause. Each trait's page lists the other genes linked to it.
Abnormality of the immune system
- Antinuclear antibody positivity
- Anti-complement component C1q antibody positivity
- Anti-ribosome Po antibody positivity
- Anti-titin antibody positivity
- Antineutrophil antibody positivity
- Decreased circulating complement C3 concentration
- Decreased circulating complement C4 concentration
- Malar rash
Show 11 more traits
- Anti-dsDNA antibody positivity
- Anti-La/SS-B antibody positivity
- Anti-nucleoporin 62 antibody positivity
- Anti-phosphatidic acid antibody positivity
- Anti-Ro52/TRIM21 antibody positivity
- Anti-Sm antibody positivity
- Anti-U1 ribonucleoprotein antibody positivity
- Discoid lupus rash
- Serositis
- Antiphospholipid antibody positivity
- Systemic lupus erythematosus
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). FCGR2B gene: Fc gamma receptor IIb. Retrieved 16 October 2026, from https://dantelabs.com/genes/fcgr2b
Dante Labs. FCGR2B gene: Fc gamma receptor IIb [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/fcgr2b
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