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Gene

TLR7

toll like receptor 7

Summary

Cytogenetic location
Xp22.2
Coordinates
Chromosome X: 12,867,072–12,890,361 (GRCh38)
Exons
3 exons across 23.3 kb
Protein
1,049 amino acids
MANE Select transcript
ENST00000380659.4NM_016562.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TLR7 yet. The test sequences your whole genome, so your data includes it all the same.

How TLR7 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome X, with a bracket where TLR7 sits. TLR7 and 6 genes near it on chromosome X, from 12,378,717 to 13,378,716.Chromosome XXp22.2p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q2812.4 Mb12.6 Mb12.8 Mb13 Mb13.2 MbFRMPD4: 11,822,423–12,724,523, forward strandFRMPD4PRPS2: 12,791,355–12,825,558, forward strandPRPS2TLR7: 12,867,072–12,890,361, forward strandTLR7TLR8: 12,906,620–12,923,169, forward strandTLR8TMSB4X: 12,975,003–12,977,228, forward strandTMSB4XFAM9C: 13,035,617–13,044,682, reverse strandFAM9CATXN3L: 13,318,647–13,320,053, reverse strandATXN3LDiagram of TLR7: 3 exons on the forward strand of chromosome XExon 3: 2 known disease-causing sitesExon 1: 12,867,072–12,867,123, 52 basesExon 2: 12,867,481–12,867,581, 101 basesExon 3: 12,885,512–12,890,361, 4,850 bases1235′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5 kb of the gene's 23.3 kb; 3,150 of those bases code for the protein.

How a genome test reads TLR7

2

positions in TLR7 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 23.3 kb of TLR7, introns included, not only the 5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TLR7 gene: toll like receptor 7. Retrieved 17 October 2026, from https://dantelabs.com/genes/tlr7

Vancouver

Dante Labs. TLR7 gene: toll like receptor 7 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tlr7

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