Gene
GPR35
G protein-coupled receptor 35
- HGNC 4492↗(opens in a new tab)
- Ensembl gene ENSG00000178623↗(opens in a new tab)
- NCBI Gene 2859↗(opens in a new tab)
Summary
- Cytogenetic location
- 2q37.3
- Coordinates
- Chromosome 2: 240,625,480–240,633,159 (GRCh38)
- Exons
- 2 exons across 7.7 kb
- Protein
- 309 amino acids
- MANE Select transcript
- ENST00000407714.2NM_005301.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How GPR35 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 3.3 kb of the gene's 7.7 kb; 930 of those bases code for the protein.
Traits linked to GPR35
The Human Phenotype Ontology lists these as features of the rare conditions GPR35 can cause. Each trait's page lists the other genes linked to it.
Laboratory abnormality
- Elevated alkaline phosphatase of hepatic origin
- Fever
- High liver enzymes
- Decreased circulating vitamin K concentration
- Deficient in vitamin D
- Fluid around lungs
- Low albumin
- Type 1 diabetes
Show 3 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). GPR35 gene: G protein-coupled receptor 35. Retrieved 17 October 2026, from https://dantelabs.com/genes/gpr35
Dante Labs. GPR35 gene: G protein-coupled receptor 35 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gpr35
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