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Gene

IRF5

interferon regulatory factor 5

Summary

Cytogenetic location
7q32.1
Coordinates
Chromosome 7: 128,937,927–128,950,038 (GRCh38)
Exons
9 exons across 12.1 kb
Protein
514 amino acids
Also known as
IRF-5
MANE Select transcript
ENST00000357234.10NM_001098629.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads IRF5 yet. The test sequences your whole genome, so your data includes it all the same.

How IRF5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 7, with a bracket where IRF5 sits. IRF5 and 16 genes near it on chromosome 7, from 128,443,983 to 129,443,982.Chromosome 77q32.1p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.3128.6 Mb128.8 Mb129 Mb129.2 Mb129.4 MbHILPDA: 128,455,825–128,458,423, forward strandHILPDAMETTL2B: 128,476,729–128,506,602, forward strandMETTL2BGARIN1A: 128,671,693–128,687,877, forward strandGARIN1AGARIN1B: 128,709,061–128,731,743, forward strandGARIN1BCALU: 128,739,292–128,773,400, forward strandCALUOPN1SW: 128,771,755–128,775,794, reverse strandOPN1SWCCDC136: 128,790,750–128,822,135, forward strandCCDC136FLNC: 128,830,292–128,859,275, forward strandFLNCKCP: 128,862,042–128,910,719, reverse strandKCPATP6V1F: 128,862,816–128,865,849, forward strandATP6V1FSPMIP1: 128,866,330–128,872,047, forward strandSPMIP1IRF5: 128,937,927–128,950,038, forward strandIRF5TNPO3: 128,954,180–129,055,208, reverse strandTNPO3TSPAN33: 129,144,690–129,177,456, forward strandTSPAN33SMO: 129,188,501–129,213,546, forward strandSMOAHCYL2: 129,225,020–129,431,841, forward strandAHCYL2STRIP2: 129,434,392–129,488,399, forward strandSTRIP2Diagram of IRF5: 9 exons on the forward strand of chromosome 7Exon 1: 128,937,927–128,938,049, 123 basesExon 2: 128,942,071–128,942,276, 206 basesExon 3: 128,945,845–128,946,034, 190 basesExon 4: 128,946,501–128,946,562, 62 basesExon 5: 128,947,023–128,947,056, 34 basesExon 6: 128,947,230–128,947,535, 306 basesExon 7: 128,947,729–128,948,121, 393 basesExon 8: 128,948,210–128,948,328, 119 basesExon 9: 128,948,573–128,950,038, 1,466 bases1234567895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.9 kb of the gene's 12.1 kb; 1,545 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). IRF5 gene: interferon regulatory factor 5. Retrieved 17 October 2026, from https://dantelabs.com/genes/irf5

Vancouver

Dante Labs. IRF5 gene: interferon regulatory factor 5 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/irf5

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