Gene
MAD2L2
mitotic arrest deficient 2 like 2
- HGNC 6764↗(opens in a new tab)
- Ensembl gene ENSG00000116670↗(opens in a new tab)
- NCBI Gene 10459↗(opens in a new tab)
Summary
- Cytogenetic location
- 1p36.22
- Coordinates
- Chromosome 1: 11,674,480–11,681,148 (GRCh38)
- Exons
- 9 exons across 6.7 kb
- Protein
- 211 amino acids
- Also known as
- MAD2B, REV7, POLZ2, FANCV
- MANE Select transcript
- ENST00000376692.9NM_006341.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How MAD2L2 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.1 kb of the gene's 6.7 kb; 636 of those bases code for the protein.
Traits linked to MAD2L2
The Human Phenotype Ontology lists these as features of the rare conditions MAD2L2 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the cardiovascular system
- Abnormal cardiac septum morphology
- Abnormal aortic morphology
- Abnormal aortic valve morphology
- Abnormal carotid artery morphology
- An opening in the wall separating the top two chambers of the heart
- Arteriovenous malformation
- Enlarged and thickened heart muscle
- Patent ductus arteriosus
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). MAD2L2 gene: mitotic arrest deficient 2 like 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/mad2l2
Dante Labs. MAD2L2 gene: mitotic arrest deficient 2 like 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mad2l2
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