Gene
MST1
macrophage stimulating 1
- HGNC 7380↗(opens in a new tab)
- Ensembl gene ENSG00000173531↗(opens in a new tab)
- NCBI Gene 4485↗(opens in a new tab)
Summary
- Cytogenetic location
- 3p21.31
- Coordinates
- Chromosome 3: 49,683,947–49,689,474 (GRCh38)
- Exons
- 18 exons across 5.5 kb
- Protein
- 725 amino acids
- Also known as
- MSP, NF15S2
- Previous symbols
- D3F15S2, HGFL, DNF15S2
- MANE Select transcript
- ENST00000449682.3NM_020998.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How MST1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 3 kb of the gene's 5.5 kb; 2,178 of those bases code for the protein.
Traits linked to MST1
The Human Phenotype Ontology lists these as features of the rare conditions MST1 can cause. Each trait's page lists the other genes linked to it.
Laboratory abnormality
- Elevated alkaline phosphatase of hepatic origin
- Fever
- High liver enzymes
- Decreased circulating vitamin K concentration
- Deficient in vitamin D
- Fluid around lungs
- Low albumin
- Type 1 diabetes
Show 3 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). MST1 gene: macrophage stimulating 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/mst1
Dante Labs. MST1 gene: macrophage stimulating 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mst1
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