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Gene

NUMA1

nuclear mitotic apparatus protein 1

Summary

Cytogenetic location
11q13.4
Coordinates
Chromosome 11: 72,002,864–72,080,542 (GRCh38)
Exons
27 exons across 77.7 kb
Protein
2,115 amino acids
Also known as
NUMA
MANE Select transcript
ENST00000393695.8NM_006185.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads NUMA1 yet. The test sequences your whole genome, so your data includes it all the same.

How NUMA1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 11, with a bracket where NUMA1 sits. NUMA1 and 20 genes near it on chromosome 11, from 71,541,703 to 72,541,702.Chromosome 1111q13.4p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2571.6 Mb71.8 Mb72 Mb72.2 Mb72.4 MbKRTAP5-9: 71,548,420–71,549,608, forward strandKRTAP5-9KRTAP5-10: 71,565,563–71,566,735, forward strandKRTAP5-10KRTAP5-11: 71,581,855–71,603,353, reverse strandKRTAP5-11XNDC1N-ZNF705EP-ALG1L9P: 71,804,997–71,928,656, reverse strandXNDC1N-ZNF705EP-ALG1L9PDEFB108B: 71,833,200–71,837,710, forward strandDEFB108BXNDC1N: 71,865,504–71,928,917, reverse strandXNDC1NDEFB131B: 71,878,453–71,884,561, forward strandDEFB131BRNF121: 71,929,005–71,997,597, forward strandRNF121IL18BP: 71,998,613–72,007,315, forward strandIL18BPNUMA1: 72,002,864–72,080,542, reverse strandNUMA1LRRC51: 72,080,286–72,096,895, forward strandLRRC51LRTOMT: 72,080,331–72,110,782, forward strandLRTOMTLAMTOR1: 72,085,520–72,103,393, reverse strandLAMTOR1TOMT: 72,103,506–72,111,546, forward strandANAPC15: 72,106,370–72,113,688, reverse strandFOLR3: 72,114,869–72,141,085, forward strandFOLR1: 72,189,529–72,199,329, forward strandFOLR1FOLR2: 72,216,601–72,221,957, forward strandFOLR2INPPL1: 72,223,524–72,239,184, forward strandINPPL1PHOX2A: 72,239,077–72,245,664, reverse strandPHOX2ACLPB: 72,285,495–72,434,680, reverse strandCLPBDiagram of NUMA1: 27 exons on the reverse strand of chromosome 11Exon 27: 72,002,864–72,003,538, 675 basesExon 26: 72,003,887–72,004,099, 213 basesExon 25: 72,004,225–72,004,341, 117 basesExon 24: 72,004,640–72,004,816, 177 basesExon 23: 72,005,233–72,005,369, 137 basesExon 22: 72,006,035–72,006,263, 229 basesExon 21: 72,007,189–72,007,435, 247 basesExon 20: 72,008,688–72,008,845, 158 basesExon 19: 72,008,967–72,009,185, 219 basesExon 18: 72,009,268–72,009,387, 120 basesExon 17: 72,010,786–72,010,854, 69 basesExon 16: 72,012,401–72,012,442, 42 basesExon 15: 72,012,895–72,016,260, 3,366 basesExon 14: 72,016,408–72,016,530, 123 basesExon 13: 72,017,687–72,017,827, 141 basesExon 12: 72,018,183–72,018,300, 118 basesExon 11: 72,018,396–72,018,513, 118 basesExon 10: 72,018,823–72,018,980, 158 basesExon 9: 72,019,494–72,019,617, 124 basesExon 8: 72,021,204–72,021,291, 88 basesExon 7: 72,022,339–72,022,419, 81 basesExon 6: 72,023,065–72,023,147, 83 basesExon 5: 72,024,274–72,024,353, 80 basesExon 4: 72,029,205–72,029,290, 86 basesExon 3: 72,035,902–72,035,975, 74 basesExon 2: 72,069,842–72,069,911, 70 basesExon 1: 72,080,458–72,080,542, 85 bases27201015′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.2 kb of the gene's 77.7 kb; 6,348 of those bases code for the protein.

Traits linked to NUMA1

The Human Phenotype Ontology lists these as features of the rare conditions NUMA1 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). NUMA1 gene: nuclear mitotic apparatus protein 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/numa1

Vancouver

Dante Labs. NUMA1 gene: nuclear mitotic apparatus protein 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/numa1

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