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Gene

SPP1

secreted phosphoprotein 1

Summary

Cytogenetic location
4q22.1
Coordinates
Chromosome 4: 87,975,714–87,983,411 (GRCh38)
Exons
7 exons across 7.7 kb
Protein
314 amino acids
Also known as
BSPI, ETA-1, lnc-PKD2-2-3
Previous symbols
BNSP, OPN
MANE Select transcript
ENST00000395080.8NM_001040058.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SPP1 yet. The test sequences your whole genome, so your data includes it all the same.

How SPP1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 4, with a bracket where SPP1 sits. SPP1 and 10 genes near it on chromosome 4, from 87,479,563 to 88,479,562.Chromosome 44q22.1p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.287.6 Mb87.8 Mb88 Mb88.2 Mb88.4 MbSPARCL1: 87,473,329–87,531,118, reverse strandSPARCL1DSPP: 87,608,529–87,616,873, forward strandDSPPDMP1: 87,650,278–87,664,361, forward strandDMP1IBSP: 87,799,546–87,813,329, forward strandIBSPMEPE: 87,821,398–87,846,814, forward strandMEPESPP1: 87,975,714–87,983,411, forward strandSPP1PKD2: 88,007,586–88,077,777, forward strandPKD2ABCG2: 88,088,127–88,231,818, reverse strandABCG2PPM1K: 88,257,620–88,284,769, reverse strandPPM1KHERC6: 88,378,734–88,443,098, forward strandHERC6HERC5: 88,457,086–88,506,188, forward strandHERC5Diagram of SPP1: 7 exons on the forward strand of chromosome 4Exon 1: 87,975,714–87,975,800, 87 basesExon 2: 87,976,882–87,976,949, 68 basesExon 3: 87,977,059–87,977,097, 39 basesExon 4: 87,980,046–87,980,126, 81 basesExon 5: 87,980,393–87,980,434, 42 basesExon 6: 87,981,475–87,981,798, 324 basesExon 7: 87,982,492–87,983,411, 920 bases12345675′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.6 kb of the gene's 7.7 kb; 945 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). SPP1 gene: secreted phosphoprotein 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/spp1

Vancouver

Dante Labs. SPP1 gene: secreted phosphoprotein 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/spp1

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