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Gene

PRTN3

proteinase 3

Summary

Cytogenetic location
19p13.3
Coordinates
Chromosome 19: 840,999–848,175 (GRCh38)
Exons
5 exons across 7.2 kb
Protein
256 amino acids
Also known as
PR-3, ACPA, C-ANCA, AGP7, MBT, P29
MANE Select transcript
ENST00000234347.10NM_002777.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PRTN3 yet. The test sequences your whole genome, so your data includes it all the same.

How PRTN3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 19, with a bracket where PRTN3 sits. PRTN3 and 44 genes near it on chromosome 19, from 344,587 to 1,344,586.Chromosome 1919p13.3p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.430.4 Mb0.6 Mb0.8 Mb1 Mb1.2 MbMIER2: 305,573–344,824, reverse strandMIER2SPMAP2: 361,747–376,026, reverse strandSPMAP2C2CD4C: 405,443–409,214, reverse strandC2CD4CSHC2: 416,315–461,100, reverse strandSHC2CIMAP1D: 462,728–474,983, reverse strandCIMAP1DMADCAM1: 489,176–505,343, forward strandMADCAM1TPGS1: 507,488–520,846, forward strandTPGS1CDC34: 531,435–542,092, forward strandCDC34GZMM: 544,034–549,924, forward strandGZMMBSG: 571,277–583,498, forward strandBSGHCN2: 589,881–617,159, forward strandHCN2POLRMT: 617,168–633,619, reverse strandPOLRMTFGF22: 639,879–644,373, forward strandFGF22RNF126: 647,526–663,336, reverse strandRNF126FSTL3: 676,366–683,793, forward strandFSTL3PRSS57: 685,546–695,498, reverse strandPRSS57PALM: 708,906–748,329, forward strandPALMMISP: 748,404–764,363, forward strandMISPPTBP1: 797,075–812,327, forward strandPTBP1PLPPR3: 810,908–822,619, reverse strandAZU1: 825,097–832,018, forward strandAZU1PRTN3: 840,999–848,175, forward strandPRTN3ELANE: 850,951–856,247, forward strandELANECFD: 859,426–869,492, forward strandCFDMED16: 867,630–893,222, reverse strandMED16R3HDM4: 896,503–913,245, reverse strandR3HDM4KISS1R: 917,287–921,005, forward strandKISS1RARID3A: 924,528–975,939, forward strandARID3AWDR18: 984,248–998,438, forward strandWDR18GRIN3B: 1,000,419–1,009,732, forward strandGRIN3BTMEM259: 1,009,615–1,021,270, reverse strandTMEM259CNN2: 1,026,270–1,039,077, forward strandCNN2ABCA7: 1,039,997–1,065,572, forward strandABCA7ARHGAP45: 1,065,923–1,087,829, forward strandARHGAP45POLR2E: 1,085,104–1,095,486, reverse strandPOLR2EGPX4: 1,103,982–1,106,791, forward strandGPX4SBNO2: 1,107,634–1,174,295, reverse strandSBNO2STK11: 1,177,558–1,228,431, forward strandSTK11CBARP: 1,228,282–1,239,465, reverse strandCBARPATP5F1D: 1,241,734–1,244,828, forward strandATP5F1DMIDN: 1,248,316–1,259,145, forward strandMIDNCIRBP: 1,259,384–1,274,880, forward strandCIRBPFAM174C: 1,275,509–1,279,244, forward strandFAM174C: 1,276,021–1,279,244, forward strandEFNA2: 1,285,873–1,301,431, forward strandDiagram of PRTN3: 5 exons on the forward strand of chromosome 19Exon 1: 840,999–841,069, 71 basesExon 2: 843,461–843,626, 166 basesExon 3: 843,893–844,034, 142 basesExon 4: 846,147–846,377, 231 basesExon 5: 847,799–848,175, 377 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1 kb of the gene's 7.2 kb; 771 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). PRTN3 gene: proteinase 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/prtn3

Vancouver

Dante Labs. PRTN3 gene: proteinase 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/prtn3

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