Gene
MLX
MAX dimerization protein MLX
- HGNC 11645↗(opens in a new tab)
- Ensembl gene ENSG00000108788↗(opens in a new tab)
- NCBI Gene 6945↗(opens in a new tab)
Summary
- Cytogenetic location
- 17q21.2
- Coordinates
- Chromosome 17: 42,567,100–42,573,203 (GRCh38)
- Exons
- 8 exons across 6.1 kb
- Protein
- 244 amino acids
- Also known as
- MAD7, MXD7, bHLHd13
- Previous symbols
- TCFL4
- MANE Select transcript
- ENST00000435881.7NM_198204.2
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read MLX, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome TestCurated reports relevant to this gene
No Genome Test report reads MLX yet. The test sequences your whole genome, so your data includes it all the same.
How MLX is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.4 kb of the gene's 6.1 kb; 735 of those bases code for the protein.
Traits linked to MLX
The Human Phenotype Ontology lists these as features of the rare conditions MLX can cause. Each trait's page lists the other genes linked to it.
Abnormality of the cardiovascular system
- Abnormal heart valve morphology
- Aneurysm
- Hypertensive crisis
- Inflammation of artery
- Inflammation of blood vessel
- Narrowing of an artery
- Abnormal aortic valve morphology
- Absent pulse
Show 15 more traits
- Asymmetric blood pressure between arms
- Blood pressure substantially higher in legs than arms
- Bulging of wall of large artery located above heart
- Heart attack
- High blood pressure
- Increased blood pressure in blood vessels of lungs
- Intermittent claudication
- Narrowing of kidney artery
- Abnormal endocardium morphology
- Aortic regurgitation
- Cardiac failure
- Disruption of blood oxygen supply to brain
- Mini stroke
- Stretched and thinned heart muscle
- Stroke
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). MLX gene: MAX dimerization protein MLX. Retrieved 16 October 2026, from https://dantelabs.com/genes/mlx
Dante Labs. MLX gene: MAX dimerization protein MLX [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/mlx
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks