Gene
IL6
interleukin 6
- HGNC 6018(opens in a new tab)
- Ensembl gene ENSG00000136244(opens in a new tab)
- NCBI Gene 3569(opens in a new tab)
Summary
- Cytogenetic location
- 7p15.3
- Coordinates
- Chromosome 7: 22,727,200–22,731,998 (GRCh38)
- Exons
- 5 exons across 4.8 kb
- Protein
- 212 amino acids
- Also known as
- IL-6, BSF2, HGF, HSF
- Previous symbols
- IFNB2
- MANE Select transcript
- ENST00000258743.10NM_000600.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Sports & Performance
- Inflammatory Recovery
How IL6 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.1 kb of the gene's 4.8 kb; 639 of those bases code for the protein.
Traits linked to IL6
The Human Phenotype Ontology lists these as features of the rare conditions IL6 can cause. Each trait's page lists the other genes linked to it.
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). IL6 gene: interleukin 6. Retrieved 16 October 2026, from https://dantelabs.com/genes/il6
Dante Labs. IL6 gene: interleukin 6 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/il6
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