Skip to content
Use your HSA or FSA funds

Gene

SRSF2

serine and arginine rich splicing factor 2

Summary

Cytogenetic location
17q25.2
Coordinates
Chromosome 17: 76,734,115–76,737,331 (GRCh38)
Exons
3 exons across 3.2 kb
Protein
221 amino acids
Also known as
SC-35, SC35, PR264, SFRS2A
Previous symbols
SFRS2
MANE Select transcript
ENST00000359995.10NM_001195427.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SRSF2 yet. The test sequences your whole genome, so your data includes it all the same.

How SRSF2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 17, with a bracket where SRSF2 sits. SRSF2 and 20 genes near it on chromosome 17, from 76,235,723 to 77,235,722.Chromosome 1717q25.2p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.376.4 Mb76.6 Mb76.8 Mb77 Mb77.2 MbRNF157: 76,142,460–76,240,662, reverse strandRNF157UBALD2: 76,265,197–76,271,298, forward strandUBALD2QRICH2: 76,274,049–76,308,282, reverse strandQRICH2PRPSAP1: 76,309,478–76,384,521, reverse strandPRPSAP1SPHK1: 76,376,584–76,387,860, forward strandSPHK1UBE2O: 76,389,456–76,453,226, reverse strandUBE2OAANAT: 76,452,749–76,470,122, forward strandAANATRHBDF2: 76,470,884–76,501,790, reverse strandRHBDF2CYGB: 76,527,356–76,551,175, reverse strandCYGBPRCD: 76,527,586–76,553,578, forward strandPRCD: 76,563,710–76,569,724, reverse strandST6GALNAC2: 76,564,424–76,586,956, reverse strandST6GALNAC2ST6GALNAC1: 76,624,228–76,643,907, reverse strandST6GALNAC1MXRA7: 76,672,551–76,711,091, reverse strandMXRA7JMJD6: 76,712,830–76,726,784, reverse strandJMJD6METTL23: 76,725,981–76,735,416, forward strandMETTL23: 76,732,978–76,738,522, forward strandSRSF2: 76,734,115–76,737,331, reverse strandSRSF2MFSD11: 76,735,865–76,789,874, forward strandMGAT5B: 76,868,134–76,950,393, forward strandMGAT5BSEC14L1: 77,088,749–77,217,101, forward strandSEC14L1Diagram of SRSF2: 3 exons on the reverse strand of chromosome 17Exon 3: 76,734,115–76,735,158, 1,044 basesExon 2: 76,736,154–76,736,464, 311 basesExon 1: 76,736,799–76,737,331, 533 bases3215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.9 kb of the gene's 3.2 kb; 666 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). SRSF2 gene: serine and arginine rich splicing factor 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/srsf2

Vancouver

Dante Labs. SRSF2 gene: serine and arginine rich splicing factor 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/srsf2

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test