Gene
CCND1
cyclin D1
- HGNC 1582↗(opens in a new tab)
- Ensembl gene ENSG00000110092↗(opens in a new tab)
- NCBI Gene 595↗(opens in a new tab)
Summary
- Cytogenetic location
- 11q13.3
- Coordinates
- Chromosome 11: 69,641,156–69,654,474 (GRCh38)
- Exons
- 5 exons across 13.3 kb
- Protein
- 295 amino acids
- Also known as
- U21B31
- Previous symbols
- BCL1, D11S287E, PRAD1
- MANE Select transcript
- ENST00000227507.3NM_053056.3
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How CCND1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4.2 kb of the gene's 13.3 kb; 888 of those bases code for the protein.
Traits linked to CCND1
The Human Phenotype Ontology lists these as features of the rare conditions CCND1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the digestive system
- Anorexia
- Abdominal pain
- Abnormality of the gastrointestinal tract
- Functional abnormality of the gastrointestinal tract
- Pancreatic cysts
- Pancreatic islet cell adenoma
- Cancer of the pancreas
- Colon cancer
Show 2 more traits
Abnormality of the genitourinary system
- Acute kidney injury
- Cancer starting in small tubes in kidneys
- Kidney damage
- Nephrotic syndrome
- Abnormality of the bladder
- Multiple kidney cysts
- Papillary cystadenoma of the epididymis
- Epididymal cyst
Show 2 more traits
Abnormality of the musculoskeletal system
- Osteopenia
- Spontaneous fracture
- Bone pain
- Breakdown of bone
- Generalized muscle weakness
- Back pain
- Compression fracture of a vertebral body
- Hunched back
Show 1 more trait
Abnormality of the nervous system
- Cerebellar hemangioblastoma
- Anxiety
- Constrictive median neuropathy
- Headache
- Peripheral neuropathy
- Pins and needles feeling
- Pressure on spinal cord
- Rise in pressure inside skull
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). CCND1 gene: cyclin D1. Retrieved 16 October 2026, from https://dantelabs.com/genes/ccnd1
Dante Labs. CCND1 gene: cyclin D1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/ccnd1
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