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Gene

GLE1

GLE1 RNA export mediator

Summary

Cytogenetic location
9q34.11
Coordinates
Chromosome 9: 128,504,719–128,542,288 (GRCh38)
Exons
16 exons across 37.6 kb
Protein
698 amino acids
Also known as
hGLE1
Previous symbols
GLE1L, LCCS1
MANE Select transcript
ENST00000309971.9NM_001003722.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads GLE1 yet. The test sequences your whole genome, so your data includes it all the same.

How GLE1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 9, with a bracket where GLE1 sits. GLE1 and 32 genes near it on chromosome 9, from 128,023,504 to 129,023,503.Chromosome 99q34.11p24.3p24.2p24.1p23p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q13q21.11q21.12q21.13q21.2q21.31q21.32q21.33q22.1q22.2q22.31q22.32q22.33q31.1q31.2q31.3q32q33.1q33.2q33.3q34.11q34.12q34.13q34.2q34.3128.2 Mb128.4 Mb128.6 Mb128.8 Mb129 MbNAIF1: 128,061,233–128,068,206, reverse strandNAIF1SLC25A25: 128,068,169–128,109,245, forward strandSLC25A25PTGES2: 128,120,693–128,128,462, reverse strandPTGES2LCN2: 128,149,071–128,153,454, forward strandLCN2BBLN: 128,160,219–128,163,928, forward strandBBLNCIZ1: 128,161,233–128,204,482, reverse strandCIZ1DNM1: 128,191,655–128,255,254, forward strandDNM1GOLGA2: 128,255,829–128,276,036, reverse strandGOLGA2SWI5: 128,275,379–128,316,123, forward strandSWI5TRUB2: 128,305,159–128,322,741, reverse strandTRUB2COQ4: 128,322,483–128,334,073, forward strandCOQ4SLC27A4: 128,340,475–128,363,283, forward strandSLC27A4URM1: 128,371,341–128,392,017, forward strandURM1CERCAM: 128,411,575–128,437,362, forward strandCERCAMODF2: 128,455,181–128,502,162, forward strandODF2GLE1: 128,504,719–128,542,288, forward strandGLE1SPTAN1: 128,552,558–128,633,663, forward strandSPTAN1DYNC2I2: 128,633,646–128,656,847, reverse strandDYNC2I2SET: 128,683,424–128,696,400, forward strandSETPKN3: 128,702,489–128,720,924, forward strandPKN3ZDHHC12: 128,720,862–128,724,146, reverse strandZDHHC12ZER1: 128,729,785–128,772,414, reverse strandZER1TBC1D13: 128,787,227–128,810,432, forward strandTBC1D13ENDOG: 128,818,451–128,822,683, forward strandENDOGSPOUT1: 128,819,651–128,829,838, reverse strandSPOUT1KYAT1: 128,819,663–128,881,931, reverse strandKYAT1KYAT1: 128,832,937–128,882,556, reverse strandLRRC8A: 128,882,120–128,918,042, forward strandLRRC8APHYHD1: 128,920,966–128,942,051, forward strandPHYHD1: 128,941,478–128,957,021, forward strandDOLK: 128,945,530–128,947,603, reverse strandDOLKNUP188: 128,947,681–129,007,836, forward strandNUP188SH3GLB2: 128,992,788–129,028,369, reverse strandSH3GLB2Diagram of GLE1: 16 exons on the forward strand of chromosome 9Exon 2: 3 known disease-causing sitesExon 3: 3 known disease-causing sitesExon 4: 4 known disease-causing sitesExon 6: 3 known disease-causing sitesExon 7: 2 known disease-causing sitesExon 8: 1 known disease-causing siteExon 10: 1 known disease-causing siteExon 12: 4 known disease-causing sitesExon 13: 2 known disease-causing sitesExon 15: 1 known disease-causing siteExon 1: 128,504,719–128,504,904, 186 basesExon 2: 128,508,876–128,509,097, 222 basesExon 3: 128,515,529–128,515,639, 111 basesExon 4: 128,522,668–128,522,816, 149 basesExon 5: 128,523,280–128,523,340, 61 basesExon 6: 128,523,592–128,523,846, 255 basesExon 7: 128,525,192–128,525,423, 232 basesExon 8: 128,527,179–128,527,291, 113 basesExon 9: 128,527,456–128,527,525, 70 basesExon 10: 128,533,513–128,533,655, 143 basesExon 11: 128,533,761–128,533,951, 191 basesExon 12: 128,536,355–128,536,484, 130 basesExon 13: 128,537,986–128,538,090, 105 basesExon 14: 128,539,616–128,539,698, 83 basesExon 15: 128,540,275–128,540,338, 64 basesExon 16: 128,541,102–128,542,288, 1,187 bases12468101214165′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.3 kb of the gene's 37.6 kb; 2,097 of those bases code for the protein.

How a genome test reads GLE1

29

positions in GLE1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 37.6 kb of GLE1, introns included, not only the 3.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). GLE1 gene: GLE1 RNA export mediator. Retrieved 17 October 2026, from https://dantelabs.com/genes/gle1

Vancouver

Dante Labs. GLE1 gene: GLE1 RNA export mediator [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gle1

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