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Trait
Conductive deafness
Clinical name: Conductive hearing impairment
An abnormality of vibrational conductance of sound to the inner ear leading to impairment of sensory perception of sound.
Summary
- Also called
- Conductive hearing loss, Conduction deafness, Hearing loss, conductive
- Body system
- Abnormality of the ear
Conductive deafnessHP:0000405
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Read the genes linked to Conductive deafness, and the rest of your genome, with one test.
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Get my Genome Test379 genes linked to Conductive deafness
Changes in these genes cause rare conditions in which Conductive deafness is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ALPK3alpha kinase 3 | Always | In 1 condition |
| AMMECR1AMMECR nuclear protein 1 | Always | In 1 condition |
| DCHS1dachsous cadherin-related 1 | Always | In 2 conditions |
| EDNRAendothelin receptor type A | Always | In 1 condition |
| FGFR2fibroblast growth factor receptor 2 | Always | In 5 conditions |
| FLT3LGfms related receptor tyrosine kinase 3 ligand | Always | In 1 condition |
| GSCgoosecoid homeobox | Always | In 1 condition |
| KICS2KICSTOR subunit 2 | Always | In 1 condition |
| NOTCH2notch receptor 2 | Always | In 1 condition |
| OFD1OFD1 centriole and centriolar satellite protein | Always | In 4 conditions |
| PIGLphosphatidylinositol glycan anchor biosynthesis class L | Always | In 1 condition |
| POLR1CRNA polymerase I and III subunit C | Always | In 2 conditions |
| RNU5B-1RNA, U5B small nuclear 1 | Always | In 1 condition |
| TAF4TATA-box binding protein associated factor 4 | Always | In 1 condition |
| TSR2TSR2 ribosome maturation factor | Always | In 1 condition |
| ABCA4ATP binding cassette subfamily A member 4 | Very often (80–99%) | In 1 condition |
| AGBL5AGBL carboxypeptidase 5 | Very often (80–99%) | In 1 condition |
| AHI1Abelson helper integration site 1 | Very often (80–99%) | In 1 condition |
| AHRaryl hydrocarbon receptor | Very often (80–99%) | In 1 condition |
| ARHGEF18Rho/Rac guanine nucleotide exchange factor 18 | Very often (80–99%) | In 1 condition |
| ARL2BPARF like GTPase 2 binding protein | Very often (80–99%) | In 1 condition |
| ARL3ARF like GTPase 3 | Very often (80–99%) | In 1 condition |
| ARL6ARF like GTPase 6 | Very often (80–99%) | In 1 condition |
| ARVCFARVCF delta catenin family member | Very often (80–99%) | In 1 condition |
| BBS1Bardet-Biedl syndrome 1 | Very often (80–99%) | In 1 condition |
| BBS2Bardet-Biedl syndrome 2 | Very often (80–99%) | In 1 condition |
| BEST1bestrophin 1 | Very often (80–99%) | In 1 condition |
| CA4carbonic anhydrase 4 | Very often (80–99%) | In 1 condition |
| CC2D2Acoiled-coil and C2 domain containing 2A | Very often (80–99%) | In 1 condition |
| CDHR1cadherin related family member 1 | Very often (80–99%) | In 1 condition |
| CERKLCERK like autophagy regulator | Very often (80–99%) | In 1 condition |
| CFAP20cilia and flagella associated protein 20 | Very often (80–99%) | In 1 condition |
| CFAP418cilia and flagella associated protein 418 | Very often (80–99%) | In 1 condition |
| CLRN1clarin 1 | Very often (80–99%) | In 1 condition |
| CNGA1cyclic nucleotide gated channel subunit alpha 1 | Very often (80–99%) | In 1 condition |
| CNGB1cyclic nucleotide gated channel subunit beta 1 | Very often (80–99%) | In 1 condition |
| COMTcatechol-O-methyltransferase | Very often (80–99%) | In 1 condition |
| COQ8Bcoenzyme Q8B | Very often (80–99%) | In 1 condition |
| CRB1crumbs cell polarity complex component 1 | Very often (80–99%) | In 1 condition |
| CRXcone-rod homeobox | Very often (80–99%) | In 1 condition |
Show 339 more genes
| Gene | How often it is seen | Conditions |
|---|---|---|
| DHDDSdehydrodolichyl diphosphate synthase subunit | Very often (80–99%) | In 1 condition |
| DHX38DEAH-box helicase 38 | Very often (80–99%) | In 1 condition |
| EYSEGF-like photoreceptor maintenance factor | Very often (80–99%) | In 1 condition |
| FAM161AFAM161 centrosomal protein A | Very often (80–99%) | In 1 condition |
| FGF9fibroblast growth factor 9 | Very often (80–99%) | In 1 condition |
| FSCN2fascin actin-bundling protein 2, retinal | Very often (80–99%) | In 1 condition |
| FSD1Lfibronectin type III and SPRY domain containing 1 like | Very often (80–99%) | In 1 condition |
| GDF5growth differentiation factor 5 | Very often (80–99%) | In 1 condition |
| GDF6growth differentiation factor 6 | Very often (80–99%) | In 2 conditions |
| GP1BBglycoprotein Ib platelet subunit beta | Very often (80–99%) | In 1 condition |
| GUCA1Bguanylate cyclase activator 1B | Very often (80–99%) | In 1 condition |
| HGSNATheparan-alpha-glucosaminide N-acetyltransferase | Very often (80–99%) | In 1 condition |
| HIRAhistone cell cycle regulator | Very often (80–99%) | In 1 condition |
| HKDC1hexokinase domain containing 1 | Very often (80–99%) | In 1 condition |
| IDH3Aisocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha | Very often (80–99%) | In 1 condition |
| IDH3Bisocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta | Very often (80–99%) | In 1 condition |
| IFT140intraflagellar transport 140 | Very often (80–99%) | In 1 condition |
| IFT172intraflagellar transport 172 | Very often (80–99%) | In 1 condition |
| IFT43intraflagellar transport 43 | Very often (80–99%) | In 1 condition |
| IFT88intraflagellar transport 88 | Very often (80–99%) | In 1 condition |
| IMPDH1inosine monophosphate dehydrogenase 1 | Very often (80–99%) | In 1 condition |
| IMPG1interphotoreceptor matrix proteoglycan 1 | Very often (80–99%) | In 1 condition |
| IMPG2interphotoreceptor matrix proteoglycan 2 | Very often (80–99%) | In 1 condition |
| JMJD1Cjumonji domain containing 1C | Very often (80–99%) | In 1 condition |
| KIAA1549KIAA1549 | Very often (80–99%) | In 1 condition |
| KIZkizuna centrosomal protein | Very often (80–99%) | In 1 condition |
| KLHL7kelch like family member 7 | Very often (80–99%) | In 1 condition |
| LMNAlamin A/C | Very often (80–99%) | In 1 condition |
| LRATlecithin retinol acyltransferase | Very often (80–99%) | In 1 condition |
| MAKmale germ cell associated kinase | Very often (80–99%) | In 1 condition |
| MAP3K7mitogen-activated protein kinase kinase kinase 7 | Very often (80–99%) | In 4 conditions |
| MERTKMER proto-oncogene, tyrosine kinase | Very often (80–99%) | In 1 condition |
| NEK2NIMA related kinase 2 | Very often (80–99%) | In 1 condition |
| NOGnoggin | Very often (80–99%) | In 4 conditions |
| NOTCH3notch receptor 3 | Very often (80–99%) | In 2 conditions |
| NR2E3nuclear receptor subfamily 2 group E member 3 | Very often (80–99%) | In 1 condition |
| NRLneural retina leucine zipper | Very often (80–99%) | In 1 condition |
| PCAREphotoreceptor cilium actin regulator | Very often (80–99%) | In 1 condition |
| PDE6Aphosphodiesterase 6A | Very often (80–99%) | In 1 condition |
| PDE6Bphosphodiesterase 6B | Very often (80–99%) | In 1 condition |
| PDE6Gphosphodiesterase 6G | Very often (80–99%) | In 1 condition |
| POLR1BRNA polymerase I subunit B | Very often (80–99%) | In 2 conditions |
| POMGNT1protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) | Very often (80–99%) | In 1 condition |
| PRCDphotoreceptor disc component | Very often (80–99%) | In 1 condition |
| PROM1prominin 1 | Very often (80–99%) | In 1 condition |
| PRPF3pre-mRNA processing factor 3 | Very often (80–99%) | In 1 condition |
| PRPF31pre-mRNA processing factor 31 | Very often (80–99%) | In 1 condition |
| PRPF4pre-mRNA splicing tri-snRNP complex factor PRPF4 | Very often (80–99%) | In 1 condition |
| PRPF6pre-mRNA processing factor 6 | Very often (80–99%) | In 1 condition |
| PRPF8pre-mRNA processing factor 8 | Very often (80–99%) | In 1 condition |
| PRPH2peripherin 2 | Very often (80–99%) | In 1 condition |
| RBP3retinol binding protein 3 | Very often (80–99%) | In 1 condition |
| RDH12retinol dehydrogenase 12 | Very often (80–99%) | In 1 condition |
| REEP6receptor accessory protein 6 | Very often (80–99%) | In 1 condition |
| RGRretinal G protein coupled receptor | Very often (80–99%) | In 1 condition |
| RHOrhodopsin | Very often (80–99%) | In 1 condition |
| RLBP1retinaldehyde binding protein 1 | Very often (80–99%) | In 1 condition |
| RNU4-2RNA, U4 small nuclear 2 | Very often (80–99%) | In 1 condition |
| RNU6-1RNA, U6 small nuclear 1 | Very often (80–99%) | In 1 condition |
| RNU6-2RNA, U6 small nuclear 2 | Very often (80–99%) | In 1 condition |
| RNU6-8RNA, U6 small nuclear 8 | Very often (80–99%) | In 1 condition |
| RNU6-9RNA, U6 small nuclear 9 | Very often (80–99%) | In 1 condition |
| ROM1retinal outer segment membrane protein 1 | Very often (80–99%) | In 1 condition |
| RP1RP1 axonemal microtubule associated | Very often (80–99%) | In 1 condition |
| RP1L1RP1 like 1 | Very often (80–99%) | In 1 condition |
| RP2RP2 activator of ARL3 GTPase | Very often (80–99%) | In 1 condition |
| RP9RP9 pre-mRNA splicing factor | Very often (80–99%) | In 1 condition |
| RPE65retinoid isomerohydrolase RPE65 | Very often (80–99%) | In 1 condition |
| RPGRretinitis pigmentosa GTPase regulator | Very often (80–99%) | In 2 conditions |
| RREB1ras responsive element binding protein 1 | Very often (80–99%) | In 1 condition |
| SAGS-antigen visual arrestin | Very often (80–99%) | In 1 condition |
| SAXO6stabilizer of axonemal microtubules 6 | Very often (80–99%) | In 1 condition |
| SCAPERS-phase cyclin A associated protein in the ER | Very often (80–99%) | In 1 condition |
| SEC24CSEC24 homolog C, COPII component | Very often (80–99%) | In 1 condition |
| SEMA4Asemaphorin 4A | Very often (80–99%) | In 1 condition |
| SETD2SET domain containing 2, histone lysine methyltransferase | Very often (80–99%) | In 1 condition |
| SF3B4splicing factor 3b subunit 4 | Very often (80–99%) | In 1 condition |
| SLC25A24solute carrier family 25 member 24 | Very often (80–99%) | In 2 conditions |
| SLC7A14solute carrier family 7 member 14 | Very often (80–99%) | In 1 condition |
| SNRNP200small nuclear ribonucleoprotein U5 subunit 200 | Very often (80–99%) | In 1 condition |
| SPATA7spermatogenesis associated 7 | Very often (80–99%) | In 1 condition |
| TBX1T-box transcription factor 1 | Very often (80–99%) | In 1 condition |
| TCOF1treacle ribosome biogenesis factor 1 | Very often (80–99%) | In 2 conditions |
| TCTN3tectonic family member 3 | Very often (80–99%) | In 2 conditions |
| TFAP2Atranscription factor AP-2 alpha | Very often (80–99%) | In 2 conditions |
| TMEM216transmembrane protein 216 | Very often (80–99%) | In 2 conditions |
| TNFRSF11ATNF receptor superfamily member 11a | Very often (80–99%) | In 1 condition |
| TOPORSTOP1 binding arginine/serine rich protein, E3 ubiquitin ligase | Very often (80–99%) | In 2 conditions |
| TTC8tetratricopeptide repeat domain 8 | Very often (80–99%) | In 1 condition |
| TUBTUB bipartite transcription factor | Very often (80–99%) | In 1 condition |
| TULP1TUB like protein 1 | Very often (80–99%) | In 1 condition |
| UFD1ubiquitin recognition factor in ER associated degradation 1 | Very often (80–99%) | In 1 condition |
| USH2Ausherin | Very often (80–99%) | In 1 condition |
| ZBTB20zinc finger and BTB domain containing 20 | Very often (80–99%) | In 1 condition |
| ZMPSTE24zinc metallopeptidase STE24 | Very often (80–99%) | In 1 condition |
| ZNF408zinc finger protein 408 | Very often (80–99%) | In 1 condition |
| ZNF513zinc finger protein 513 | Very often (80–99%) | In 1 condition |
| ADAMTSL2ADAMTS like 2 | Often (30–79%) | In 1 condition |
| ALX1ALX homeobox 1 | Often (30–79%) | In 1 condition |
| AMER1APC membrane recruitment protein 1 | Often (30–79%) | In 2 conditions |
| BMP2bone morphogenetic protein 2 | Often (30–79%) | In 1 condition |
| BRD4bromodomain containing 4 | Often (30–79%) | In 1 condition |
| CACNA1Bcalcium voltage-gated channel subunit alpha1 B | Often (30–79%) | In 1 condition |
| CDH1cadherin 1 | Often (30–79%) | In 2 conditions |
| COG1component of oligomeric golgi complex 1 | Often (30–79%) | In 1 condition |
| CPLANE1ciliogenesis and planar polarity effector complex subunit 1 | Often (30–79%) | In 2 conditions |
| CPLX1complexin 1 | Often (30–79%) | In 2 conditions |
| CTBP1C-terminal binding protein 1 | Often (30–79%) | In 1 condition |
| CTNNB1catenin beta 1 | Often (30–79%) | In 1 condition |
| CTNND1catenin delta 1 | Often (30–79%) | In 1 condition |
| DDR2discoidin domain receptor tyrosine kinase 2 | Often (30–79%) | In 1 condition |
| DHODHdihydroorotate dehydrogenase (quinone) | Often (30–79%) | In 2 conditions |
| DVL1dishevelled segment polarity protein 1 | Often (30–79%) | In 1 condition |
| EYA1EYA transcriptional coactivator and phosphatase 1 | Often (30–79%) | In 4 conditions |
| FAM149B1family with sequence similarity 149 member B1 | Often (30–79%) | In 1 condition |
| FANCFFA complementation group F | Often (30–79%) | In 1 condition |
| FAT4FAT atypical cadherin 4 | Often (30–79%) | In 3 conditions |
| FBN1fibrillin 1 | Often (30–79%) | In 2 conditions |
| FGFR3fibroblast growth factor receptor 3 | Often (30–79%) | In 4 conditions |
| FGFRL1fibroblast growth factor receptor like 1 | Often (30–79%) | In 1 condition |
| FLNAfilamin A | Often (30–79%) | In 3 conditions |
| FOXL1forkhead box L1 | Often (30–79%) | In 1 condition |
| FRAS1Fraser extracellular matrix complex subunit 1 | Often (30–79%) | In 2 conditions |
| GJA1gap junction protein alpha 1 | Often (30–79%) | In 3 conditions |
| GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta | Often (30–79%) | In 2 conditions |
| HAX1HCLS1 associated protein X-1 | Often (30–79%) | In 1 condition |
| HDAC8histone deacetylase 8 | Often (30–79%) | In 1 condition |
| HYAL2hyaluronidase 2 | Often (30–79%) | In 1 condition |
| IL11RAinterleukin 11 receptor subunit alpha | Often (30–79%) | In 1 condition |
| KDM6Alysine demethylase 6A | Often (30–79%) | In 1 condition |
| KIAA0753KIAA0753 | Often (30–79%) | In 1 condition |
| KIF7kinesin family member 7 | Often (30–79%) | In 1 condition |
| KMT2Dlysine methyltransferase 2D | Often (30–79%) | In 2 conditions |
| LETM1leucine zipper and EF-hand containing transmembrane protein 1 | Often (30–79%) | In 1 condition |
| LONP1lon peptidase 1, mitochondrial | Often (30–79%) | In 1 condition |
| LTBP3latent transforming growth factor beta binding protein 3 | Often (30–79%) | In 1 condition |
| MASP1MBL associated serine protease 1 | Often (30–79%) | In 1 condition |
| MAU2MAU2 sister chromatid cohesion factor | Often (30–79%) | In 1 condition |
| NEK1NIMA related kinase 1 | Often (30–79%) | In 2 conditions |
| NFIXnuclear factor I X | Often (30–79%) | In 1 condition |
| NIPBLNIPBL cohesin loading factor | Often (30–79%) | In 2 conditions |
| NSD2nuclear receptor binding SET domain protein 2 | Often (30–79%) | In 1 condition |
| PCGF2polycomb group ring finger 2 | Often (30–79%) | In 1 condition |
| PDE6Dphosphodiesterase 6D | Often (30–79%) | In 1 condition |
| POLR1DRNA polymerase I and III subunit D | Often (30–79%) | In 2 conditions |
| POU3F4POU class 3 homeobox 4 | Often (30–79%) | In 2 conditions |
| PRDM5PR/SET domain 5 | Often (30–79%) | In 1 condition |
| PTH1Rparathyroid hormone 1 receptor | Often (30–79%) | In 1 condition |
| RAD21RAD21 cohesin complex component | Often (30–79%) | In 2 conditions |
| RAI1retinoic acid induced 1 | Often (30–79%) | In 1 condition |
| SALL4spalt like transcription factor 4 | Often (30–79%) | In 1 condition |
| SIX1SIX homeobox 1 | Often (30–79%) | In 4 conditions |
| SIX5SIX homeobox 5 | Often (30–79%) | In 1 condition |
| SMC1Astructural maintenance of chromosomes 1A | Often (30–79%) | In 1 condition |
| SMC3structural maintenance of chromosomes 3 | Often (30–79%) | In 1 condition |
| SNRPBsmall nuclear ribonucleoprotein polypeptides B and B1 | Often (30–79%) | In 2 conditions |
| SOSTsclerostin | Often (30–79%) | In 1 condition |
| SOX9SRY-box transcription factor 9 | Often (30–79%) | In 1 condition |
| SP7Sp7 transcription factor | Often (30–79%) | In 1 condition |
| TMEM231transmembrane protein 231 | Often (30–79%) | In 1 condition |
| ZNF469zinc finger protein 469 | Often (30–79%) | In 1 condition |
| ABCC6ATP binding cassette subfamily C member 6 | Sometimes (5–29%) | In 1 condition |
| ADAMTS3ADAM metallopeptidase with thrombospondin type 1 motif 3 | Sometimes (5–29%) | In 1 condition |
| AFF4ALF transcription elongation factor 4 | Sometimes (5–29%) | In 1 condition |
| ANKHANKH inorganic pyrophosphate transport regulator | Sometimes (5–29%) | In 1 condition |
| ARHGAP29Rho GTPase activating protein 29 | Sometimes (5–29%) | In 1 condition |
| ARHGEF38Rho guanine nucleotide exchange factor 38 | Sometimes (5–29%) | In 1 condition |
| ARID2AT-rich interaction domain 2 | Sometimes (5–29%) | In 1 condition |
| B3GLCTbeta 3-glucosyltransferase | Sometimes (5–29%) | In 1 condition |
| BMP4bone morphogenetic protein 4 | Sometimes (5–29%) | In 1 condition |
| BORCS5BLOC-1 related complex subunit 5 | Sometimes (5–29%) | In 1 condition |
| BRWD1bromodomain and WD repeat domain containing 1 | Sometimes (5–29%) | In 1 condition |
| CASZ1castor zinc finger 1 | Sometimes (5–29%) | In 1 condition |
| CCBE1collagen and calcium binding EGF domains 1 | Sometimes (5–29%) | In 2 conditions |
| CCDC39coiled-coil domain 39 molecular ruler complex subunit | Sometimes (5–29%) | In 1 condition |
| CCDC40coiled-coil domain 40 molecular ruler complex subunit | Sometimes (5–29%) | In 1 condition |
| CCNOcyclin O | Sometimes (5–29%) | In 1 condition |
| CFAP221cilia and flagella associated protein 221 | Sometimes (5–29%) | In 1 condition |
| CFAP298cilia and flagella associated protein 298 | Sometimes (5–29%) | In 1 condition |
| CFAP300cilia and flagella associated protein 300 | Sometimes (5–29%) | In 2 conditions |
| CFAP74cilia and flagella associated protein 74 | Sometimes (5–29%) | In 1 condition |
| CHRNGcholinergic receptor nicotinic gamma subunit | Sometimes (5–29%) | In 2 conditions |
| CLXNcalaxin | Sometimes (5–29%) | In 1 condition |
| CNOT3CCR4-NOT transcription complex subunit 3 | Sometimes (5–29%) | In 1 condition |
| COBLL1cordon-bleu WH2 repeat protein like 1 | Sometimes (5–29%) | In 1 condition |
| COL2A1collagen type II alpha 1 chain | Sometimes (5–29%) | In 3 conditions |
| CREBBPCREB binding lysine acetyltransferase | Sometimes (5–29%) | In 2 conditions |
| DAW1dynein assembly factor with WD repeats 1 | Sometimes (5–29%) | In 1 condition |
| DLG1discs large MAGUK scaffold protein 1 | Sometimes (5–29%) | In 1 condition |
| DLSTdihydrolipoamide S-succinyltransferase | Sometimes (5–29%) | In 1 condition |
| DLX4distal-less homeobox 4 | Sometimes (5–29%) | In 1 condition |
| DNAAF1dynein axonemal assembly factor 1 | Sometimes (5–29%) | In 1 condition |
| DNAAF11dynein axonemal assembly factor 11 | Sometimes (5–29%) | In 1 condition |
| DNAAF19dynein axonemal assembly factor 19 | Sometimes (5–29%) | In 1 condition |
| DNAAF2dynein axonemal assembly factor 2 | Sometimes (5–29%) | In 1 condition |
| DNAAF3dynein axonemal assembly factor 3 | Sometimes (5–29%) | In 1 condition |
| DNAAF4dynein axonemal assembly factor 4 | Sometimes (5–29%) | In 1 condition |
| DNAAF5dynein axonemal assembly factor 5 | Sometimes (5–29%) | In 1 condition |
| DNAAF6dynein axonemal assembly factor 6 | Sometimes (5–29%) | In 1 condition |
| DNAH1dynein axonemal heavy chain 1 | Sometimes (5–29%) | In 1 condition |
| DNAH11dynein axonemal heavy chain 11 | Sometimes (5–29%) | In 1 condition |
| DNAH5dynein axonemal heavy chain 5 | Sometimes (5–29%) | In 1 condition |
| DNAH7dynein axonemal heavy chain 7 | Sometimes (5–29%) | In 1 condition |
| DNAH9dynein axonemal heavy chain 9 | Sometimes (5–29%) | In 1 condition |
| DNAI1dynein axonemal intermediate chain 1 | Sometimes (5–29%) | In 2 conditions |
| DNAI2dynein axonemal intermediate chain 2 | Sometimes (5–29%) | In 1 condition |
| DNAJB13DnaJ heat shock protein family (Hsp40) member B13 | Sometimes (5–29%) | In 1 condition |
| DNAL1dynein axonemal light chain 1 | Sometimes (5–29%) | In 1 condition |
| DNMT3ADNA methyltransferase 3 alpha | Sometimes (5–29%) | In 1 condition |
| DOT1LDOT1 like histone lysine methyltransferase | Sometimes (5–29%) | In 1 condition |
| DRC1dynein regulatory complex subunit 1 | Sometimes (5–29%) | In 1 condition |
| DRC2dynein regulatory complex subunit 2 | Sometimes (5–29%) | In 1 condition |
| DRC4dynein regulatory complex subunit 4 | Sometimes (5–29%) | In 2 conditions |
| EFTUD2elongation factor Tu GTP binding domain containing 2 | Sometimes (5–29%) | In 2 conditions |
| EIF5Aeukaryotic translation initiation factor 5A | Sometimes (5–29%) | In 1 condition |
| ELMO2engulfment and cell motility 2 | Sometimes (5–29%) | In 1 condition |
| ENPP1ectonucleotide pyrophosphatase/phosphodiesterase 1 | Sometimes (5–29%) | In 1 condition |
| EP300EP300 lysine acetyltransferase | Sometimes (5–29%) | In 1 condition |
| EPAS1endothelial PAS domain protein 1 | Sometimes (5–29%) | In 1 condition |
| ERCC6ERCC excision repair 6, chromatin remodeling factor | Sometimes (5–29%) | In 1 condition |
| ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit | Sometimes (5–29%) | In 1 condition |
| EXT1exostosin glycosyltransferase 1 | Sometimes (5–29%) | In 1 condition |
| FBXO22F-box protein 22 | Sometimes (5–29%) | In 1 condition |
| FGF10fibroblast growth factor 10 | Sometimes (5–29%) | In 1 condition |
| FHfumarate hydratase | Sometimes (5–29%) | In 1 condition |
| FKBP14FKBP prolyl isomerase 14 | Sometimes (5–29%) | In 1 condition |
| FLNBfilamin B | Sometimes (5–29%) | In 2 conditions |
| FOXJ1forkhead box J1 | Sometimes (5–29%) | In 1 condition |
| FREM2FRAS1 related extracellular matrix 2 | Sometimes (5–29%) | In 1 condition |
| GABRDgamma-aminobutyric acid type A receptor subunit delta | Sometimes (5–29%) | In 1 condition |
| GALNT2polypeptide N-acetylgalactosaminyltransferase 2 | Sometimes (5–29%) | In 1 condition |
| GAS2L2growth arrest specific 2 like 2 | Sometimes (5–29%) | In 1 condition |
| GRHL3grainyhead like transcription factor 3 | Sometimes (5–29%) | In 2 conditions |
| GRIP1glutamate receptor interacting protein 1 | Sometimes (5–29%) | In 1 condition |
| HDAC4histone deacetylase 4 | Sometimes (5–29%) | In 1 condition |
| HLA-Bmajor histocompatibility complex, class I, B | Sometimes (5–29%) | In 1 condition |
| HLA-DRB1major histocompatibility complex, class II, DR beta 1 | Sometimes (5–29%) | In 1 condition |
| HNRNPKheterogeneous nuclear ribonucleoprotein K | Sometimes (5–29%) | In 2 conditions |
| HSPG2heparan sulfate proteoglycan 2 | Sometimes (5–29%) | In 1 condition |
| HYDINHYDIN axonemal central pair apparatus protein | Sometimes (5–29%) | In 1 condition |
| IRF6interferon regulatory factor 6 | Sometimes (5–29%) | In 2 conditions |
| KCNAB2potassium voltage-gated channel subfamily A regulatory beta subunit 2 | Sometimes (5–29%) | In 1 condition |
| KIF1Bkinesin family member 1B | Sometimes (5–29%) | In 1 condition |
| LRRC56leucine rich repeat containing 56 | Sometimes (5–29%) | In 1 condition |
| LUZP1leucine zipper protein 1 | Sometimes (5–29%) | In 1 condition |
| MAXMYC associated transcriptional regulator X | Sometimes (5–29%) | In 1 condition |
| MCIDASmulticiliate differentiation and DNA synthesis associated cell cycle protein | Sometimes (5–29%) | In 1 condition |
| MDH2malate dehydrogenase 2 | Sometimes (5–29%) | In 1 condition |
| MED16mediator complex subunit 16 | Sometimes (5–29%) | In 1 condition |
| MMP23Bmatrix metallopeptidase 23B | Sometimes (5–29%) | In 1 condition |
| MSX1msh homeobox 1 | Sometimes (5–29%) | In 2 conditions |
| MYCNMYCN proto-oncogene, bHLH transcription factor | Sometimes (5–29%) | In 1 condition |
| MYH3myosin heavy chain 3 | Sometimes (5–29%) | In 1 condition |
| NAXDNAD(P)HX dehydratase | Sometimes (5–29%) | In 1 condition |
| NECTIN1nectin cell adhesion molecule 1 | Sometimes (5–29%) | In 2 conditions |
| NEK10NIMA related kinase 10 | Sometimes (5–29%) | In 1 condition |
| NF1neurofibromin 1 | Sometimes (5–29%) | In 1 condition |
| NME5NME/NM23 family member 5 | Sometimes (5–29%) | In 1 condition |
| NME8NME/NM23 family member 8 | Sometimes (5–29%) | In 1 condition |
| NOTCH2NLCnotch 2 N-terminal like C | Sometimes (5–29%) | In 1 condition |
| ODAD1outer dynein arm docking complex subunit 1 | Sometimes (5–29%) | In 1 condition |
| ODAD2outer dynein arm docking complex subunit 2 | Sometimes (5–29%) | In 1 condition |
| ODAD3outer dynein arm docking complex subunit 3 | Sometimes (5–29%) | In 1 condition |
| ODAD4outer dynein arm docking complex subunit 4 | Sometimes (5–29%) | In 1 condition |
| P4HA2prolyl 4-hydroxylase subunit alpha 2 | Sometimes (5–29%) | In 1 condition |
| PDGFRAplatelet derived growth factor receptor alpha | Sometimes (5–29%) | In 1 condition |
| PDPNpodoplanin | Sometimes (5–29%) | In 1 condition |
| PGM3phosphoglucomutase 3 | Sometimes (5–29%) | In 2 conditions |
| PIK3C2Aphosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha | Sometimes (5–29%) | In 1 condition |
| PORcytochrome p450 oxidoreductase | Sometimes (5–29%) | In 2 conditions |
| PRDM16PR/SET domain 16 | Sometimes (5–29%) | In 1 condition |
| PRKCZprotein kinase C zeta | Sometimes (5–29%) | In 1 condition |
| PTPN22protein tyrosine phosphatase non-receptor type 22 | Sometimes (5–29%) | In 1 condition |
| RECQL4RecQ like helicase 4 | Sometimes (5–29%) | In 2 conditions |
| REREarginine-glutamic acid dipeptide repeats | Sometimes (5–29%) | In 1 condition |
| RETret proto-oncogene | Sometimes (5–29%) | In 2 conditions |
| RIC1RIC1 partner of RAB6A GEF complex | Sometimes (5–29%) | In 1 condition |
| RPS26ribosomal protein S26 | Sometimes (5–29%) | In 1 condition |
| RSPH1radial spoke head component 1 | Sometimes (5–29%) | In 1 condition |
| RSPH3radial spoke head 3 | Sometimes (5–29%) | In 1 condition |
| RSPH4Aradial spoke head component 4A | Sometimes (5–29%) | In 1 condition |
| RSPH9radial spoke head component 9 | Sometimes (5–29%) | In 1 condition |
| SDHAsuccinate dehydrogenase complex flavoprotein subunit A | Sometimes (5–29%) | In 1 condition |
| SDHAF2succinate dehydrogenase complex assembly factor 2 | Sometimes (5–29%) | In 1 condition |
| SDHBsuccinate dehydrogenase complex iron sulfur subunit B | Sometimes (5–29%) | In 2 conditions |
| SDHCsuccinate dehydrogenase complex subunit C | Sometimes (5–29%) | In 1 condition |
| SDHDsuccinate dehydrogenase complex subunit D | Sometimes (5–29%) | In 3 conditions |
| SH2B1SH2B adaptor protein 1 | Sometimes (5–29%) | In 1 condition |
| SKISKI proto-oncogene | Sometimes (5–29%) | In 3 conditions |
| SLC25A11solute carrier family 25 member 11 | Sometimes (5–29%) | In 1 condition |
| SLC35C1solute carrier family 35 member C1 | Sometimes (5–29%) | In 1 condition |
| SMCHD1structural maintenance of chromosomes flexible hinge domain containing 1 | Sometimes (5–29%) | In 1 condition |
| SNF8SNF8 subunit of ESCRT-II | Sometimes (5–29%) | In 1 condition |
| SPAG1sperm associated antigen 1 | Sometimes (5–29%) | In 1 condition |
| SPEF2sperm flagellar and cilia associated 2 | Sometimes (5–29%) | In 1 condition |
| SPENspen family transcriptional repressor | Sometimes (5–29%) | In 2 conditions |
| SRCAPSnf2 related CREBBP activator protein | Sometimes (5–29%) | In 2 conditions |
| STAC3SH3 and cysteine rich domain 3 | Sometimes (5–29%) | In 2 conditions |
| STK36serine/threonine kinase 36 | Sometimes (5–29%) | In 1 condition |
| TBX22T-box transcription factor 22 | Sometimes (5–29%) | In 1 condition |
| TMEM127transmembrane protein 127 | Sometimes (5–29%) | In 1 condition |
| TP63tumor protein p63 | Sometimes (5–29%) | In 3 conditions |
| TRPS1transcriptional repressor GATA binding 1 | Sometimes (5–29%) | In 1 condition |
| TTC12tetratricopeptide repeat domain 12 | Sometimes (5–29%) | In 1 condition |
| TWIST1twist family bHLH transcription factor 1 | Sometimes (5–29%) | In 1 condition |
| UBBubiquitin B | Sometimes (5–29%) | In 2 conditions |
| UBE4Bubiquitination factor E4B | Sometimes (5–29%) | In 1 condition |
| VHLvon Hippel-Lindau tumor suppressor | Sometimes (5–29%) | In 2 conditions |
| ZFXzinc finger protein X-linked | Sometimes (5–29%) | In 1 condition |
| ZMYND10zinc finger MYND-type containing 10 | Sometimes (5–29%) | In 1 condition |
| ABCA12ATP binding cassette subfamily A member 12 | Rarely (1–4%) | In 1 condition |
| ALOX12Barachidonate 12-lipoxygenase, 12R type | Rarely (1–4%) | In 1 condition |
| ALOXE3arachidonate epidermal lipoxygenase 3 | Rarely (1–4%) | In 1 condition |
| APC2APC regulator of Wnt signaling pathway 2 | Rarely (1–4%) | In 1 condition |
| ASPRV1aspartic peptidase retroviral like 1 | Rarely (1–4%) | In 1 condition |
| CA2carbonic anhydrase 2 | Rarely (1–4%) | In 1 condition |
| CYP4F22cytochrome P450 family 4 subfamily F member 22 | Rarely (1–4%) | In 1 condition |
| LIPNlipase family member N | Rarely (1–4%) | In 1 condition |
| NIPAL4NIPA like domain containing 4 | Rarely (1–4%) | In 1 condition |
| NSD1nuclear receptor binding SET domain protein 1 | Rarely (1–4%) | In 2 conditions |
| SDR9C7short chain dehydrogenase/reductase family 9C member 7 | Rarely (1–4%) | In 1 condition |
| SULT2B1sulfotransferase family 2B member 1 | Rarely (1–4%) | In 1 condition |
| TAF11TATA-box binding protein associated factor 11 | Rarely (1–4%) | In 1 condition |
| TGM1transglutaminase 1 | Rarely (1–4%) | In 1 condition |
| ACVR1activin A receptor type 1 | Not recorded | In 1 condition |
| ALX3ALX homeobox 3 | Not recorded | In 1 condition |
| CDCA7cell division cycle associated 7 | Not recorded | In 1 condition |
| CREB3L1cAMP responsive element binding protein 3 like 1 | Not recorded | In 1 condition |
| FANCIFA complementation group I | Not recorded | In 1 condition |
| GMNNgeminin DNA replication inhibitor | Not recorded | In 1 condition |
| LRP5LDL receptor related protein 5 | Not recorded | In 1 condition |
| MEOX1mesenchyme homeobox 1 | Not recorded | In 1 condition |
| PRRX1paired related homeobox 1 | Not recorded | In 1 condition |
| RAB23RAB23, member RAS oncogene family | Not recorded | In 1 condition |
| RPS23ribosomal protein S23 | Not recorded | In 1 condition |
| SF3B2splicing factor 3b subunit 2 | Not recorded | In 1 condition |
| TMEM67transmembrane protein 67 | Not recorded | In 1 condition |
| TSHZ1teashirt zinc finger homeobox 1 | Not recorded | In 1 condition |
| TXNL4Athioredoxin like 4A | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
- Mixed hearing impairment42 genes
- Bilateral conductive hearing impairment9 genes
- Progressive conductive hearing impairment3 genes
- Mild conductive hearing impairment2 genes
- Unilateral conductive hearing impairment2 genes
- Congenital conductive hearing impairment1 gene
- Severe conductive hearing impairment1 gene
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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