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Gene

ALX3

ALX homeobox 3

Summary

Cytogenetic location
1p13.3
Coordinates
Chromosome 1: 110,059,870–110,070,672 (GRCh38)
Exons
4 exons across 10.8 kb
Protein
343 amino acids
Previous symbols
FND
MANE Select transcript
ENST00000647563.2NM_006492.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ALX3 yet. The test sequences your whole genome, so your data includes it all the same.

How ALX3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 1, with a bracket where ALX3 sits. ALX3 and 21 genes near it on chromosome 1, from 109,565,271 to 110,565,270.Chromosome 11p13.3p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44109.6 Mb109.8 Mb110 Mb110.2 Mb110.4 MbGNAI3: 109,548,582–109,600,195, forward strandGNAI3GNAT2: 109,601,407–109,619,929, reverse strandGNAT2AMPD2: 109,616,104–109,632,055, forward strandAMPD2GSTM4: 109,656,069–109,665,800, forward strandGSTM4GSTM2: 109,667,348–109,709,552, forward strandGSTM2GSTM1: 109,687,309–109,709,552, forward strandGSTM1GSTM5: 109,711,746–109,776,019, forward strandGSTM5GSTM3: 109,731,688–109,741,038, reverse strandGSTM3EPS8L3: 109,750,078–109,764,062, reverse strandEPS8L3CSF1: 109,910,242–109,930,993, forward strandCSF1AHCYL1: 109,984,721–110,023,742, forward strandAHCYL1STRIP1: 110,031,577–110,074,641, forward strandSTRIP1ALX3: 110,059,870–110,070,672, reverse strandALX3UBL4B: 110,112,443–110,113,947, forward strandUBL4BSLC6A17: 110,150,482–110,202,202, forward strandSLC6A17KCNC4: 110,210,095–110,283,100, forward strandKCNC4RBM15: 110,338,506–110,346,681, forward strandRBM15SLC16A4: 110,362,847–110,391,082, reverse strandSLC16A4LAMTOR5: 110,401,249–110,407,963, reverse strandLAMTOR5PROK1: 110,451,058–110,457,358, forward strandPROK1KCNA10: 110,517,217–110,519,175, reverse strandKCNA10KCNA2: 110,519,837–110,631,474, reverse strandKCNA2Diagram of ALX3: 4 exons on the reverse strand of chromosome 1Exon 4: 1 known disease-causing siteExon 2: 2 known disease-causing sitesExon 4: 110,059,870–110,061,041, 1,172 basesExon 3: 110,061,435–110,061,563, 129 basesExon 2: 110,064,587–110,064,903, 317 basesExon 1: 110,070,336–110,070,672, 337 bases43215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2 kb of the gene's 10.8 kb; 1,032 of those bases code for the protein.

How a genome test reads ALX3

3

positions in ALX3 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 10.8 kb of ALX3, introns included, not only the 2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ALX3 gene: ALX homeobox 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/alx3

Vancouver

Dante Labs. ALX3 gene: ALX homeobox 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/alx3

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