Gene
FBXO22
F-box protein 22
- HGNC 13593(opens in a new tab)
- Ensembl gene ENSG00000167196(opens in a new tab)
- NCBI Gene 26263(opens in a new tab)
Summary
- Cytogenetic location
- 15q24.2
- Coordinates
- Chromosome 15: 75,903,878–75,942,511 (GRCh38)
- Exons
- 7 exons across 38.6 kb
- Protein
- 403 amino acids
- Also known as
- FBX22, FISTC1
- MANE Select transcript
- ENST00000308275.8NM_147188.3
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How FBXO22 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 10.7 kb of the gene's 38.6 kb; 1,212 of those bases code for the protein.
Traits linked to FBXO22
The Human Phenotype Ontology lists these as features of the rare conditions FBXO22 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the genitourinary system
- Abnormal kidney location
- Absent kidney
- Bilateral renal dysplasia
- Cystic kidney disease
- Hyperechogenic kidneys
- Short penis
- Small kidneys
- Undescended testes
Show 3 more traits
Abnormality of the cardiovascular system
- Biventricular hypertrophy
- Narrowing of aorta
- An opening in the wall separating the top two chambers of the heart
- Patent ductus arteriosus
- Patent foramen ovale
- Hole in heart wall separating two lower heart chambers
- Hypoplastic tricuspid valve
- Increased blood pressure in blood vessels of lungs
Show 2 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). FBXO22 gene: F-box protein 22. Retrieved 16 October 2026, from https://dantelabs.com/genes/fbxo22
Dante Labs. FBXO22 gene: F-box protein 22 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/fbxo22
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