Gene
FGF10
fibroblast growth factor 10
- HGNC 3666↗(opens in a new tab)
- Ensembl gene ENSG00000070193↗(opens in a new tab)
- NCBI Gene 2255↗(opens in a new tab)
Summary
- Cytogenetic location
- 5p12
- Coordinates
- Chromosome 5: 44,300,247–44,389,420 (GRCh38)
- Exons
- 3 exons across 89.2 kb
- Protein
- 208 amino acids
- MANE Select transcript
- ENST00000264664.5NM_004465.2
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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No Genome Test report reads FGF10 yet. The test sequences your whole genome, so your data includes it all the same.
How FGF10 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 6.1 kb of the gene's 89.2 kb; 627 of those bases code for the protein.
How a genome test reads FGF10
16
positions in FGF10 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 89.2 kb of FGF10, introns included, not only the 6.1 kb of exons.
Traits linked to FGF10
The Human Phenotype Ontology lists these as features of the rare conditions FGF10 can cause. Each trait's page lists the other genes linked to it.
Abnormality of head or neck
- Absent lacrimal punctum
- Dental cavities
- Abnormal dentition
- Absent tear duct
- Abnormal lacrimal duct morphology
- Abnormal lacrimal gland morphology
- Abnormal tooth enamel
- Abnormality of the salivary glands
Show 18 more traits
- Absent eyelashes
- Decreased salivary flow
- Dry eye syndrome
- Eye folds
- Thin dental enamel
- Widely spaced teeth
- Abnormal facial shape
- Absent tear gland
- Decreased size of tooth
- Failure of development of between one and six teeth
- Hypoplasia of the lacrimal punctum
- Keratoconjunctivitis
- Bifid uvula
- Blockage of the rear opening of the nasal cavity
- Cleft of the mouth
- Little lower jaw
- Lost smell
- Underdeveloped tear gland
Abnormality of limbs
- Partial duplication of the thumb bones
- Abnormality of fingers or toes
- Short thumb
- Abnormality of the thumb
- Absent thumb
- Curvature of digit
- Duplication of thumb phalanx
- Finger syndactyly
Show 3 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). FGF10 gene: fibroblast growth factor 10. Retrieved 16 October 2026, from https://dantelabs.com/genes/fgf10
Dante Labs. FGF10 gene: fibroblast growth factor 10 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/fgf10
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