Skip to content
Use your HSA or FSA funds

Gene

FLNB

filamin B

Summary

Cytogenetic location
3p14.3
Coordinates
Chromosome 3: 58,008,422–58,172,251 (GRCh38)
Exons
46 exons across 163.8 kb
Protein
2,602 amino acids
Also known as
TAP, TABP, ABP-278, FH1
Previous symbols
FLN1L, LRS1
MANE Select transcript
ENST00000295956.9NM_001457.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads FLNB yet. The test sequences your whole genome, so your data includes it all the same.

How FLNB is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 3, with a bracket where FLNB sits. FLNB and 13 genes near it on chromosome 3, from 57,590,337 to 58,590,336.Chromosome 33p14.3p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q2957.6 Mb57.8 Mb58 Mb58.2 Mb58.4 MbPDE12: 57,556,249–57,656,494, forward strandPDE12ARF4: 57,571,363–57,598,220, reverse strandARF4DENND6A: 57,625,454–57,693,127, reverse strandDENND6ASLMAP: 57,755,450–57,931,461, forward strandSLMAPFLNB: 58,008,422–58,172,251, forward strandFLNBDNASE1L3: 58,191,375–58,214,697, reverse strandDNASE1L3ABHD6: 58,237,502–58,296,814, forward strandABHD6RPP14: 58,306,239–58,324,695, forward strandRPP14HTD2: 58,306,239–58,324,695, forward strandHTD2PXK: 58,332,579–58,426,867, forward strandPXKPDHB: 58,425,143–58,434,012, reverse strandPDHBKCTD6: 58,491,078–58,502,584, forward strandKCTD6ACOX2: 58,504,544–58,537,400, reverse strandACOX2FAM107A: 58,564,114–58,627,651, reverse strandFAM107ADiagram of FLNB: 46 exons on the forward strand of chromosome 3Exon 1: 2 known disease-causing sitesExon 2: 3 known disease-causing sitesExon 3: 1 known disease-causing siteExon 4: 4 known disease-causing sitesExon 6: 1 known disease-causing siteExon 7: 3 known disease-causing sitesExon 8: 2 known disease-causing sitesExon 9: 1 known disease-causing siteExon 10: 2 known disease-causing sitesExon 11: 1 known disease-causing siteExon 13: 1 known disease-causing siteExon 16: 1 known disease-causing siteExon 19: 3 known disease-causing sitesExon 21: 3 known disease-causing sitesExon 24: 1 known disease-causing siteExon 27: 5 known disease-causing sitesExon 28: 5 known disease-causing sitesExon 29: 4 known disease-causing sitesExon 30: 1 known disease-causing siteExon 34: 1 known disease-causing siteExon 35: 1 known disease-causing siteExon 1: 58,008,422–58,008,856, 435 basesExon 2: 58,077,046–58,077,294, 249 basesExon 3: 58,078,717–58,078,814, 98 basesExon 4: 58,081,629–58,081,776, 148 basesExon 5: 58,094,836–58,094,954, 119 basesExon 6: 58,096,141–58,096,218, 78 basesExon 7: 58,097,815–58,097,977, 163 basesExon 8: 58,098,711–58,098,908, 198 basesExon 9: 58,102,203–58,102,340, 138 basesExon 10: 58,103,959–58,104,085, 127 basesExon 11: 58,105,080–58,105,216, 137 basesExon 12: 58,106,680–58,106,873, 194 basesExon 13: 58,108,458–58,108,571, 114 basesExon 14: 58,109,179–58,109,322, 144 basesExon 15: 58,109,576–58,109,699, 124 basesExon 16: 58,110,010–58,110,170, 161 basesExon 17: 58,111,791–58,111,881, 91 basesExon 18: 58,112,149–58,112,318, 170 basesExon 19: 58,118,872–58,118,989, 118 basesExon 20: 58,121,241–58,121,503, 263 basesExon 21: 58,123,093–58,123,690, 598 basesExon 22: 58,124,332–58,124,505, 174 basesExon 23: 58,125,581–58,125,743, 163 basesExon 24: 58,126,602–58,126,762, 161 basesExon 25: 58,130,741–58,130,908, 168 basesExon 26: 58,132,808–58,132,931, 124 basesExon 27: 58,134,616–58,134,772, 157 basesExon 28: 58,135,979–58,136,168, 190 basesExon 29: 58,138,282–58,138,529, 248 basesExon 30: 58,141,858–58,141,929, 72 basesExon 31: 58,142,650–58,142,752, 103 basesExon 32: 58,143,473–58,143,613, 141 basesExon 33: 58,145,921–58,146,049, 129 basesExon 34: 58,146,820–58,146,993, 174 basesExon 35: 58,148,206–58,148,364, 159 basesExon 36: 58,148,649–58,148,852, 204 basesExon 37: 58,149,850–58,150,002, 153 basesExon 38: 58,150,105–58,150,227, 123 basesExon 39: 58,153,375–58,153,641, 267 basesExon 40: 58,154,791–58,154,928, 138 basesExon 41: 58,155,960–58,156,075, 116 basesExon 42: 58,159,554–58,159,686, 133 basesExon 43: 58,163,154–58,163,330, 177 basesExon 44: 58,168,440–58,168,658, 219 basesExon 45: 58,169,590–58,169,793, 204 basesExon 46: 58,170,575–58,172,251, 1,677 bases110203040465′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 9.4 kb of the gene's 163.8 kb; 7,809 of those bases code for the protein.

How a genome test reads FLNB

53

positions in FLNB where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 163.8 kb of FLNB, introns included, not only the 9.4 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). FLNB gene: filamin B. Retrieved 16 October 2026, from https://dantelabs.com/genes/flnb

Vancouver

Dante Labs. FLNB gene: filamin B [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/flnb

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test