Gene
SLC25A24
solute carrier family 25 member 24
- HGNC 20662↗(opens in a new tab)
- Ensembl gene ENSG00000085491↗(opens in a new tab)
- NCBI Gene 29957↗(opens in a new tab)
Summary
- Cytogenetic location
- 1p13.3
- Coordinates
- Chromosome 1: 108,134,043–108,200,343 (GRCh38)
- Exons
- 10 exons across 66.3 kb
- Protein
- 477 amino acids
- Also known as
- DKFZp586G0123, APC1, SCAMC1, SCAMC-1
- MANE Select transcript
- ENST00000565488.6NM_013386.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome TestCurated reports relevant to this gene
No Genome Test report reads SLC25A24 yet. The test sequences your whole genome, so your data includes it all the same.
How SLC25A24 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4.2 kb of the gene's 66.3 kb; 1,434 of those bases code for the protein.
How a genome test reads SLC25A24
2
positions in SLC25A24 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 66.3 kb of SLC25A24, introns included, not only the 4.2 kb of exons.
Traits linked to SLC25A24
The Human Phenotype Ontology lists these as features of the rare conditions SLC25A24 can cause. Each trait's page lists the other genes linked to it.
Abnormality of head or neck
- Absent/underdeveloped tear glands
- Beaked nose
- Broad forehead
- Broad head shape
- Coronal craniosynostosis
- Deformity of the skull
- Downward slanting of the opening between the eyelids
- Flattened bony protrusion above eyes
Show 36 more traits
- Midface retrusion
- Short opening between the eyelids
- Triangular face
- Wider-than-typical soft spot of skull
- Abnormal dentition
- Abnormality of the eyelid
- Big lower jaw
- Congenital craniofacial dysostosis
- Decreased bone formation of skull
- Decreased number of teeth
- Drooping lower lip
- Eye folds
- Failure of development of more than six teeth
- Long eyelashes in irregular rows
- Low frontal hairline
- Thick eyebrow
- Abnormality of the skull
- Abnormally small head
- Aplasia/Hypoplasia of the nasal bone
- Decreased size of maxilla
- Little lower jaw
- Cleft upper eyelid
- High, narrow palate
- Decreased size of tooth
- Depressed nasal bridge
- Long philtrum
- Low hairline at back of neck
- Monobrow
- Narrow mouth
- Protruding tongue
- Receding chin
- Short nose
- Smooth philtrum
- Sparse scalp hair
- Tall shaped head
- Thin red part of the upper lip
Abnormality of the eye
- Abnormality of the eye
- Abnormality of vision
- Cross-eyed
- Involuntary, rapid, rhythmic eye movements
- Wide-set eyes
- Astigmatism
- Hardening of skin and connective tissue
- Abnormally small eyeball
Show 2 more traits
Abnormality of the cardiovascular system
- Prominent veins
- Abnormality of the heart
- Bulge in wall of large artery that carries blood away from heart
- Patent ductus arteriosus
- Aortic valve has two leaflets rather than three
- Increased blood pressure in blood vessels of lungs
- An opening in the wall separating the top two chambers of the heart
- Left ventricular hypertrophy
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). SLC25A24 gene: solute carrier family 25 member 24. Retrieved 17 October 2026, from https://dantelabs.com/genes/slc25a24
Dante Labs. SLC25A24 gene: solute carrier family 25 member 24 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/slc25a24
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