Gene
KICS2
KICSTOR subunit 2
- HGNC 26517↗(opens in a new tab)
- Ensembl gene ENSG00000174206↗(opens in a new tab)
- NCBI Gene 144577↗(opens in a new tab)
Summary
- Cytogenetic location
- 12q14.2
- Coordinates
- Chromosome 12: 64,191,080–64,222,296 (GRCh38)
- Exons
- 3 exons across 31.2 kb
- Protein
- 445 amino acids
- Also known as
- FLJ32549
- Previous symbols
- C12orf66
- MANE Select transcript
- ENST00000398055.8NM_152440.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How KICS2 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4.2 kb of the gene's 31.2 kb; 1,338 of those bases code for the protein.
Traits linked to KICS2
The Human Phenotype Ontology lists these as features of the rare conditions KICS2 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Difficulty falling asleep
- Difficulty staying asleep
- Focal autonomic seizure
- Grand mal seizures
- Intellectual disability
- Intellectual disability, mild
- Intellectual disability, severe
- IQ between 34 and 49
Show 21 more traits
- Nail-biting
- Receptive language delay
- Abnormality of movement
- Absent speech development
- Attention deficit
- Delayed ability to walk
- Delayed speech and language development
- Epilepsy
- Gliosis
- Jerking
- Periventricular white matter hyperintensities
- Repetitive movements
- Speech apraxia
- Aggressive behavior
- Autism
- Difficulty sleeping
- Dystonia
- Loss of developmental milestones
- Paroxysmal bursts of laughter
- Self-injurious behavior
- Stereotypical hand wringing
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). KICS2 gene: KICSTOR subunit 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/kics2
Dante Labs. KICS2 gene: KICSTOR subunit 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/kics2
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