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Gene

CTBP1

C-terminal binding protein 1

Summary

Cytogenetic location
4p16.3
Coordinates
Chromosome 4: 1,211,445–1,249,130 (GRCh38)
Exons
10 exons across 37.7 kb
Protein
429 amino acids
Also known as
BARS
MANE Select transcript
ENST00000382952.8NM_001012614.2
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads CTBP1 yet. The test sequences your whole genome, so your data includes it all the same.

How CTBP1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 4, with a bracket where CTBP1 sits. CTBP1 and 17 genes near it on chromosome 4, from 730,288 to 1,730,287.Chromosome 44p16.3p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.20.8 Mb1 Mb1.2 Mb1.4 Mb1.6 MbPCGF3: 705,748–770,089, forward strandPCGF3CPLX1: 784,957–827,043, reverse strandCPLX1GAK: 849,275–932,411, reverse strandGAKTMEM175: 932,153–958,989, forward strandTMEM175DGKQ: 958,884–986,895, reverse strandDGKQSLC26A1: 978,992–997,659, reverse strandSLC26A1IDUA: 986,997–1,008,344, forward strandIDUAFGFRL1: 1,008,649–1,026,901, forward strandFGFRL1RNF212: 1,056,247–1,113,697, reverse strandRNF212SPON2: 1,166,928–1,208,962, reverse strandSPON2CTBP1: 1,211,445–1,249,130, reverse strandCTBP1MAEA: 1,289,839–1,340,148, forward strandMAEAUVSSA: 1,345,691–1,395,989, forward strandUVSSANKX1-1: 1,402,932–1,406,442, reverse strandNKX1-1FAM53A: 1,617,915–1,684,356, reverse strandFAM53ASLBP: 1,692,731–1,712,344, reverse strandSLBPTACC3: 1,712,858–1,745,178, forward strandTACC3TMEM129: 1,715,951–1,721,367, reverse strandTMEM129Diagram of CTBP1: 10 exons on the reverse strand of chromosome 4Exon 9: 1 known disease-causing siteExon 10: 1,211,445–1,212,423, 979 basesExon 9: 1,212,913–1,213,030, 118 basesExon 8: 1,213,478–1,213,605, 128 basesExon 7: 1,214,343–1,214,473, 131 basesExon 6: 1,215,991–1,216,205, 215 basesExon 5: 1,225,360–1,225,566, 207 basesExon 4: 1,228,199–1,228,343, 145 basesExon 3: 1,238,183–1,238,337, 155 basesExon 2: 1,241,325–1,241,519, 195 basesExon 1: 1,248,916–1,249,130, 215 bases10864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.5 kb of the gene's 37.7 kb; 1,290 of those bases code for the protein.

Sequencing CTBP1

1

position in CTBP1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 37.7 kb of CTBP1, introns included, not only the 2.5 kb of exons.

Traits linked to CTBP1

The Human Phenotype Ontology lists these as features of the rare conditions CTBP1 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.17-8666dff2.

Cite this page

APA

Dante Labs. (n.d.). CTBP1 gene: C-terminal binding protein 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/ctbp1

Vancouver

Dante Labs. CTBP1 gene: C-terminal binding protein 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ctbp1

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