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Gene

FSCN2

fascin actin-bundling protein 2, retinal

Summary

Cytogenetic location
17q25.3
Coordinates
Chromosome 17: 81,528,377–81,537,130 (GRCh38)
Exons
5 exons across 8.8 kb
Protein
492 amino acids
Also known as
RP30, RFSN
MANE Select transcript
ENST00000417245.7NM_012418.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads FSCN2 yet. The test sequences your whole genome, so your data includes it all the same.

How FSCN2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 17, with a bracket where FSCN2 sits. FSCN2 and 38 genes near it on chromosome 17, from 81,032,754 to 82,032,753.Chromosome 1717q25.3p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.381.2 Mb81.4 Mb81.6 Mb81.8 Mb82 MbBAIAP2: 81,035,122–81,117,434, forward strandBAIAP2LMTK1: 81,110,487–81,166,228, reverse strandLMTK1PVALEF: 81,165,507–81,183,166, forward strandPVALEFCEP131: 81,189,583–81,223,014, reverse strandCEP131TEPSIN: 81,228,277–81,239,095, reverse strandTEPSINNDUFAF8: 81,239,305–81,241,310, forward strandNDUFAF8SLC38A10: 81,244,811–81,295,567, reverse strandSLC38A10BAHCC1: 81,395,450–81,466,331, forward strandBAHCC1ACTG1: 81,509,413–81,523,847, reverse strandACTG1FSCN2: 81,528,377–81,537,130, forward strandFSCN2FAAP100: 81,539,885–81,553,961, reverse strandFAAP100NPLOC4: 81,556,887–81,648,465, reverse strandNPLOC4TSPAN10: 81,637,171–81,648,754, forward strandTSPAN10PDE6G: 81,650,459–81,663,112, reverse strandPDE6GOXLD1: 81,665,033–81,666,635, reverse strandOXLD1CCDC137: 81,666,698–81,673,904, forward strandARL16: 81,681,160–81,683,797, reverse strandHGS: 81,683,326–81,703,138, forward strandMRPL12: 81,703,357–81,711,112, forward strand: 81,703,371–81,720,539, forward strandSLC25A10: 81,711,951–81,721,969, forward strandGCGR: 81,803,105–81,814,023, forward strandGCGRMCRIP1: 81,821,790–81,833,302, reverse strandMCRIP1PPP1R27: 81,833,488–81,835,056, reverse strandPPP1R27P4HB: 81,843,158–81,860,856, reverse strandP4HBARHGDIA: 81,867,719–81,871,378, reverse strandARHGDIAALYREF: 81,887,830–81,891,835, reverse strandALYREFANAPC11: 81,890,669–81,900,991, forward strandNPB: 81,900,745–81,902,905, forward strandNPBPCYT2: 81,900,958–81,911,507, reverse strandSIRT7: 81,911,939–81,921,323, reverse strandMAFG: 81,918,270–81,927,769, reverse strandPYCR1: 81,932,378–81,942,412, reverse strandPYCR1MYADML2: 81,939,645–81,947,233, reverse strandNOTUM: 81,952,507–81,963,328, reverse strandNOTUMASPSCR1: 81,976,807–82,018,698, forward strandASPSCR1CENPX: 82,018,590–82,024,107, reverse strandCENPXLRRC45: 82,023,269–82,031,153, forward strandLRRC45RAC3: 82,031,192–82,034,218, forward strandRAC3Diagram of FSCN2: 5 exons on the forward strand of chromosome 17Exon 1: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 1: 81,528,377–81,529,357, 981 basesExon 2: 81,535,052–81,535,208, 157 basesExon 3: 81,536,146–81,536,267, 122 basesExon 4: 81,536,622–81,536,789, 168 basesExon 5: 81,536,875–81,537,130, 256 bases123455′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.7 kb of the gene's 8.8 kb; 1,479 of those bases code for the protein.

How a genome test reads FSCN2

3

positions in FSCN2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 8.8 kb of FSCN2, introns included, not only the 1.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). FSCN2 gene: fascin actin-bundling protein 2, retinal. Retrieved 16 October 2026, from https://dantelabs.com/genes/fscn2

Vancouver

Dante Labs. FSCN2 gene: fascin actin-bundling protein 2, retinal [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/fscn2

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