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Gene

KIAA0753

KIAA0753

Summary

Cytogenetic location
17p13.1
Coordinates
Chromosome 17: 6,578,147–6,640,711 (GRCh38)
Exons
19 exons across 62.6 kb
Protein
967 amino acids
Also known as
OFIP, MNR
MANE Select transcript
ENST00000361413.8NM_014804.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads KIAA0753 yet. The test sequences your whole genome, so your data includes it all the same.

How KIAA0753 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 17, with a bracket where KIAA0753 sits. KIAA0753 and 21 genes near it on chromosome 17, from 6,109,429 to 7,109,428.Chromosome 1717p13.1p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.36.2 Mb6.4 Mb6.6 Mb6.8 Mb7 MbWSCD1: 6,057,807–6,124,427, forward strandWSCD1AIPL1: 6,393,693–6,435,199, reverse strandAIPL1PIMREG: 6,443,544–6,451,469, forward strandPIMREGPITPNM3: 6,451,263–6,556,567, reverse strandPITPNM3: 6,578,031–6,640,711, reverse strandKIAA0753: 6,578,147–6,640,711, reverse strandKIAA0753TXNDC17: 6,640,712–6,646,374, forward strandTXNDC17MED31: 6,643,311–6,652,290, reverse strandMED31C17orf100: 6,651,762–6,693,202, forward strandSLC13A5: 6,684,715–6,713,377, reverse strandSLC13A5XAF1: 6,755,375–6,775,647, forward strandXAF1FBXO39: 6,776,210–6,797,101, forward strandFBXO39TEKT1: 6,789,133–6,831,761, reverse strandTEKT1ALOX12: 6,996,049–7,010,754, forward strandALOX12RNASEK: 7,012,412–7,014,535, forward strandRNASEKRNASEK-C17orf49: 7,012,635–7,017,520, forward strandRNASEK-C17orf49BACC1: 7,014,480–7,017,544, forward strandBACC1BCL6B: 7,023,050–7,030,290, forward strandSLC16A13: 7,035,981–7,041,031, forward strandSLC16A11: 7,041,605–7,044,092, reverse strandCLEC10A: 7,074,537–7,081,166, reverse strandCLEC10AASGR2: 7,100,166–7,116,603, reverse strandASGR2Diagram of KIAA0753: 19 exons on the reverse strand of chromosome 17Exon 18: 2 known disease-causing sitesExon 15: 1 known disease-causing siteExon 11: 1 known disease-causing siteExon 10: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 4: 2 known disease-causing sitesExon 3: 1 known disease-causing siteExon 19: 6,578,147–6,579,864, 1,718 basesExon 18: 6,589,779–6,590,003, 225 basesExon 17: 6,590,510–6,590,630, 121 basesExon 16: 6,594,972–6,595,053, 82 basesExon 15: 6,596,158–6,596,343, 186 basesExon 14: 6,599,237–6,599,320, 84 basesExon 13: 6,600,380–6,600,458, 79 basesExon 12: 6,606,873–6,606,962, 90 basesExon 11: 6,607,181–6,607,270, 90 basesExon 10: 6,608,348–6,608,464, 117 basesExon 9: 6,609,994–6,610,160, 167 basesExon 8: 6,611,919–6,612,148, 230 basesExon 7: 6,620,788–6,620,998, 211 basesExon 6: 6,622,882–6,623,097, 216 basesExon 5: 6,623,509–6,623,571, 63 basesExon 4: 6,624,755–6,624,861, 107 basesExon 3: 6,628,117–6,628,741, 625 basesExon 2: 6,635,011–6,635,171, 161 basesExon 1: 6,640,637–6,640,711, 75 bases191816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.6 kb of the gene's 62.6 kb; 2,904 of those bases code for the protein.

How a genome test reads KIAA0753

11

positions in KIAA0753 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 62.6 kb of KIAA0753, introns included, not only the 4.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). KIAA0753 gene: KIAA0753. Retrieved 17 October 2026, from https://dantelabs.com/genes/kiaa0753

Vancouver

Dante Labs. KIAA0753 gene: KIAA0753 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/kiaa0753

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