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Gene

PCGF2

polycomb group ring finger 2

Summary

Cytogenetic location
17q12
Coordinates
Chromosome 17: 38,733,898–38,748,336 (GRCh38)
Exons
11 exons across 14.4 kb
Protein
344 amino acids
Also known as
MEL-18
Previous symbols
ZNF144, RNF110
MANE Select transcript
ENST00000620225.5NM_007144.3
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads PCGF2 yet. The test sequences your whole genome, so your data includes it all the same.

How PCGF2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 17, with a bracket where PCGF2 sits. PCGF2 and 21 genes near it on chromosome 17, from 38,241,117 to 39,241,116.Chromosome 1717q12p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.338.4 Mb38.6 Mb38.8 Mb39 Mb39.2 MbMRPL45: 38,297,023–38,324,140, forward strandMRPL45GPR179: 38,324,571–38,343,956, reverse strandGPR179SOCS7: 38,351,844–38,405,593, forward strandSOCS7ARHGAP23: 38,419,260–38,512,385, forward strandARHGAP23SRCIN1: 38,530,031–38,605,952, reverse strandSRCIN1EPOP: 38,671,703–38,674,957, reverse strandEPOPMLLT6: 38,705,244–38,729,799, forward strandMLLT6CISD3: 38,730,151–38,735,605, forward strandCISD3PCGF2: 38,733,898–38,748,336, reverse strandPCGF2PSMB3: 38,752,726–38,803,069, forward strandPSMB3PIP4K2B: 38,765,691–38,800,126, reverse strandPIP4K2BCWC25: 38,800,441–38,825,646, reverse strandCWC25SPMAP1: 38,835,086–38,841,438, reverse strandSPMAP1RPL23: 38,847,860–38,868,644, reverse strandRPL23LASP1: 38,869,185–38,921,771, forward strandLASP1LASP1NB: 38,925,565–38,929,381, forward strandLASP1NBFBXO47: 38,936,432–38,967,407, reverse strandFBXO47PLXDC1: 39,063,313–39,154,394, reverse strandPLXDC1ARL5C: 39,156,894–39,167,484, reverse strandARL5CCACNB1: 39,173,453–39,197,877, reverse strandCACNB1RPL19: 39,200,282–39,204,840, forward strandRPL19STAC2: 39,210,540–39,225,945, reverse strandSTAC2Diagram of PCGF2: 11 exons on the reverse strand of chromosome 17Exon 4: 2 known disease-causing sitesExon 11: 38,733,898–38,735,600, 1,703 basesExon 10: 38,736,090–38,736,170, 81 basesExon 9: 38,738,353–38,738,448, 96 basesExon 8: 38,738,541–38,738,595, 55 basesExon 7: 38,738,753–38,738,861, 109 basesExon 6: 38,739,068–38,739,118, 51 basesExon 5: 38,739,198–38,739,253, 56 basesExon 4: 38,739,586–38,739,682, 97 basesExon 3: 38,740,291–38,740,442, 152 basesExon 2: 38,747,879–38,747,971, 93 basesExon 1: 38,748,196–38,748,336, 141 bases1110864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.6 kb of the gene's 14.4 kb; 1,035 of those bases code for the protein.

Sequencing PCGF2

2

positions in PCGF2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 14.4 kb of PCGF2, introns included, not only the 2.6 kb of exons.

Traits linked to PCGF2

The Human Phenotype Ontology lists these as features of the rare conditions PCGF2 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PCGF2 gene: polycomb group ring finger 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/pcgf2

Vancouver

Dante Labs. PCGF2 gene: polycomb group ring finger 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/pcgf2

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